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  1. 1.
    0539089 - ÚOCHB 2021 RIV eng P - Patent Document
    Kotora, Martin - Prchalová, Eva - Adamski, J. - Möller, G. - Štěpánek, Ondřej - Bartůněk, Petr - Sedlák, David - Hajdúch, M. - Džubák, P.
    15β-substituted estrone derivatives as selective inhibitors of 17β-hydroxysteroid-dehydrogenases, method of preparation and use thereof.
    2020. Owner: Ústav organické chemie a biochemie AV ČR, v. v. i. - Ústav molekulární genetiky AV ČR, v. v. i. - Univerzita Palackého v Olomouci - Helmholtz Zentrum München GmbH. Date of the patent acceptance: 01.09.2020. Patent Number: US10579826
    R&D Projects: GA MŠMT LO1220
    Institutional support: RVO:61388963 ; RVO:68378050
    Keywords : 17β-hydroxysteroid dehydrogenase type 1 * 17βHSD1 * inhibitor
    OECD category: Organic chemistry
    https://worldwide.espacenet.com/publicationDetails/originalDocument?CC=US&NR=10759826B2&KC=B2&FT=D&ND=4&date=20200901&DB=&locale=en_EP
    Permanent Link: http://hdl.handle.net/11104/0317085
     
     
  2. 2.
    0499597 - ÚOCHB 2019 RIV cze P - Patent Document
    Kotora, Martin - Prchalová, Eva - Adamski, J. - Möller, G. - Štěpánek, Ondřej - Bartůněk, Petr - Sedlák, David - Hajdúch, M. - Džubák, P.
    15β-substituované deriváty estronu jako selektivní inhibitory 17β-hydroxysteroiddehydrogenáz.
    [15β-substituted estrone derivatives as selective inhibitors of 17β-hydroxysteroid dehydrogenases.]
    2018. Owner: Ústav organické chemie a biochemie AV ČR, v. v. i. - Ústav molekulární genetiky AV ČR, v. v. i. - Univerzita Palackého v Olomouci - Helmholtz Zentrum München GmbH. Date of the patent acceptance: 11.07.2018. Patent Number: 307437
    R&D Projects: GA MŠMT LO1220
    Institutional support: RVO:61388963 ; RVO:68378050
    Keywords : 17β-hydroxysteroid dehydrogenase type 1 * 17βHSD1 * inhibitor
    OECD category: Organic chemistry; Organic chemistry (UMG-J)
    https://isdv.upv.cz/doc/FullFiles/Patents/FullDocuments/307/307437.pdf
    Permanent Link: http://hdl.handle.net/11104/0291958
    FileDownloadSizeCommentaryVersionAccess
    CZ 307437_EN.pdf1181.8 KBOtherrequire
    CZ 307437_CZ.pdf12881.6 KBOtherrequire
     
     
  3. 3.
    0424816 - ÚMG 2015 RIV eng P - Patent Document
    Novák, P. - Sedlák, David - Bartůněk, Petr - Kotora, Martin
    Ligands of estrogen receptors and method of their preparation and pharmaceuticals comprising them.
    2013. Owner: Ústav molekulární genetiky AV ČR, v. v. i. - Ústav organické chemie a biochemie AV ČR, v. v. i. - Univerzita Karlova v Praze, Přírodovědecka fakulta. Date of the patent acceptance: 13.02.2013. Patent Number: EP2274316
    R&D Projects: GA MŠMT LM2011022; GA MŠMT LC06077
    Institutional support: RVO:68378050 ; RVO:61388963
    Keywords : Estrogen receptor * Selective agonist * Cancer * Inflammation
    Subject RIV: EB - Genetics ; Molecular Biology
    https://data.epo.org/publication-server/pdf-document?pn=2274316&ki=B1&cc=EP
    Permanent Link: http://hdl.handle.net/11104/0236244
     
     
  4. 4.
    0388664 - ÚMG 2013 RIV eng P - Patent Document
    Novák, P. - Sedlák, David - Bartůněk, Petr - Kotora, Martin
    Ligands of estrogen receptors α and β, method of their preparation, and pharmaceuticals comprising them.
    2012. Owner: Ústav molekulární genetiky AV ČR, v. v. i. - Ústav organické chemie a biochemie AV ČR, v. v. i. - Přírodovědecká fakulta UK v Praze. Date of the patent acceptance: 18.12.2012. Patent Number: US8334280
    Institutional research plan: CEZ:AV0Z50520514; CEZ:AV0Z40550506
    Keywords : estrogen receptor ligand * hormone therapy * cancer therapy
    Subject RIV: EB - Genetics ; Molecular Biology; CE - Biochemistry (UOCHB-X)
    http://patft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=8334280.PN.&OS=PN/8334280&RS=PN/8334280
    Permanent Link: http://hdl.handle.net/11104/0217584
    FileDownloadSizeCommentaryVersionAccess
    0388664.pdf91.6 MBPublisher’s postprintrequire
     
     
  5. 5.
    0325391 - ÚMG 2009 RIV CZ cze P - Patent Document
    Novák, P. - Sedlák, David - Bartůněk, Petr - Kotora, Martin
    Ligandy estrogenových receptorů alfa a beta, způsob jejich přípravy a farmaceutické prostředky, které je obsahují.
    [Estrogen receptor alpha and beta ligands, methods for their preparation, and pharmaceutical compositions containing them.]
    Česká republika: Úřad průmyslového vlastnictví, 2009. Owner: Přírodovědecká fakulta UK, Ústav molekulární genetiky AV ČR, Ústav organické chemie a biochemie AV ČR. Date of the patent registration: 05.05.2008. Date of the patent acceptance: 26.03.2009. Patent Number: 300 376
    R&D Projects: GA MŠMT(CZ) LC06077
    Institutional research plan: CEZ:AV0Z50520514; CEZ:AV0Z40550506
    Keywords : estrogen receptor * agonist * therapy
    Subject RIV: EB - Genetics ; Molecular Biology
    Permanent Link: http://hdl.handle.net/11104/0172826
     
     


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