Search results
- 1.0574023 - FGÚ 2024 RIV US eng J - Journal Article
Pavluch, Vojtěch - Špaček, Tomáš - Engstová, Hana - Dlasková, Andrea - Ježek, Petr
Possible frequent multiple mitochondrial DNA copies in a single nucleoid in HeLa cells.
Scientific Reports. Roč. 13, č. 1 (2023), č. článku 5788. ISSN 2045-2322. E-ISSN 2045-2322
R&D Projects: GA ČR(CZ) GA21-01205S; GA ČR(CZ) GA22-02203S; GA ČR(CZ) GA23-05798S
Institutional support: RVO:67985823
Keywords : HeLa cells * mitochondrial proteins * fluorescence in situ hybridization
OECD category: Physiology (including cytology)
Impact factor: 4.6, year: 2022
Method of publishing: Open access
https://doi.org/10.1038/s41598-023-33012-6
Permanent Link: https://hdl.handle.net/11104/0344385 - 2.0532352 - FGÚ 2021 RIV US eng J - Journal Article
Plecitá-Hlavatá, Lydie - Engstová, Hana - Holendová, Blanka - Tauber, Jan - Špaček, Tomáš - Petrásková, Lucie - Křen, Vladimír - Špačková, Jitka - Gotvaldová, Klára - Ježek, Jan - Dlasková, Andrea - Smolková, Katarína - Ježek, Petr
Mitochondrial Superoxide Production Decreases on Glucose-Stimulated Insulin Secretion in Pancreatic beta Cells Due to Decreasing Mitochondrial Matrix NADH/NAD(+) Ratio.
Antioxidants & Redox Signaling. Roč. 33, č. 12 (2020), s. 789-815. ISSN 1523-0864. E-ISSN 1557-7716
R&D Projects: GA ČR(CZ) GA16-06700S; GA ČR(CZ) GA17-01813S; GA ČR(CZ) GA20-00408S
Institutional support: RVO:67985823 ; RVO:61388971
Keywords : mitochondrial superoxide generation * pancreatic beta cells * glucose-stimulated insulin secretion * Complex I * NADH/NAD(+) ratio * fluorescence lifetime imaging
OECD category: Endocrinology and metabolism (including diabetes, hormones); Analytical chemistry (MBU-M)
Impact factor: 8.401, year: 2020
Method of publishing: Open access
https://www.liebertpub.com/doi/10.1089/ars.2019.7800
Permanent Link: http://hdl.handle.net/11104/0310854 - 3.0517532 - FGÚ 2020 RIV NL eng J - Journal Article
Dlasková, Andrea - Špaček, Tomáš - Engstová, Hana - Špačková, Jitka - Schröfel, A. - Holendová, Blanka - Smolková, Katarína - Plecitá-Hlavatá, Lydie - Ježek, Petr
Mitochondrial cristae narrowing upon higher 2-oxoglutarate load.
Biochimica Et Biophysica Acta-Bioenergetics. Roč. 1860, č. 8 (2019), s. 659-678. ISSN 0005-2728. E-ISSN 1879-2650
R&D Projects: GA MŠMT(CZ) LM2015062
Research Infrastructure: Czech-BioImaging - 90062
Institutional support: RVO:67985823
Keywords : mitochondrial cristae * hypoxia * Dimethyl-2-oxoglutarate * 3D super-resolution microscopy
OECD category: Cell biology
Impact factor: 3.465, year: 2019
Method of publishing: Open access with time embargo
https://doi.org/10.1016/j.bbabio.2019.06.015
Permanent Link: http://hdl.handle.net/11104/0302868 - 4.0504242 - FGÚ 2020 RIV GB eng J - Journal Article
Ježek, Petr - Špaček, Tomáš - Tauber, Jan - Pavluch, Vojtěch
Mitochondrial Nucleoids: Superresolution microscopy analysis.
International Journal of Biochemistry and Cell Biology. Roč. 106, Jan (2019), s. 21-25. ISSN 1357-2725. E-ISSN 1878-5875
R&D Projects: GA ČR(CZ) GA16-04788S; GA ČR(CZ) GA17-01813S
Institutional support: RVO:67985823
Keywords : mtDNA * nucleoids * 3D superresolution microscopy * TFAM
OECD category: Cell biology
Impact factor: 3.673, year: 2019
Method of publishing: Limited access
https://doi.org/10.1016/j.biocel.2018.10.012
Permanent Link: http://hdl.handle.net/11104/0295920 - 5.0493403 - FGÚ 2019 RIV NL eng J - Journal Article
Dlasková, Andrea - Engstová, Hana - Špaček, Tomáš - Kahancová, Anežka - Pavluch, Vojtěch - Smolková, Katarína - Špačková, Jitka - Bartoš, Martin - Plecitá-Hlavatá, Lydie - Ježek, Petr
3D super-resolution microscopy reflects mitochondrial cristae alternations and mtDNA nucleoid size and distribution.
Biochimica Et Biophysica Acta-Bioenergetics. Roč. 1859, č. 9 (2018), s. 829-844. ISSN 0005-2728. E-ISSN 1879-2650
R&D Projects: GA ČR(CZ) GA17-08565S; GA ČR(CZ) GJ15-02022Y; GA ČR(CZ) GA16-06700S; GA ČR(CZ) GA16-04788S
Institutional support: RVO:67985823
Keywords : 3D super-resolution microscopy * Ripley's K-function * distances frequency distribution histogram * mitochondrial cristae ATP-synthase alpha subunit * mitochondrial nucleoids
OECD category: Physiology (including cytology)
Impact factor: 4.441, year: 2018
Permanent Link: http://hdl.handle.net/11104/0286764 - 6.0485798 - FGÚ 2018 RIV GB eng J - Journal Article
Špaček, Tomáš - Pavluch, Vojtěch - Alán, Lukáš - Capková, Nikola - Engstová, Hana - Dlasková, Andrea - Berková, Z. - Saudek, F. - Ježek, Petr
Nkx6.1 decline accompanies mitochondrial DNA reduction but subtle nucleoid size decrease in pancreatic islet beta-cells of diabetic Goto Kakizaki rats.
Scientific Reports. Roč. 7, Nov 15 (2017), č. článku 15674. ISSN 2045-2322. E-ISSN 2045-2322
R&D Projects: GA ČR(CZ) GA13-02033S; GA ČR(CZ) GA13-06666S; GA MŠMT(CZ) ED1.1.00/02.0109
Institutional support: RVO:67985823
Keywords : GK rat * superresolution fluorescence * microscopy reveals * binding-protein * insulin-release
OECD category: Cell biology
Impact factor: 4.122, year: 2017
Permanent Link: http://hdl.handle.net/11104/0281250 - 7.0473778 - BTÚ 2018 RIV US eng J - Journal Article
Rohlenová, Kateřina - Sachaphibulkij, K. - Stursa, J. - Bezawork-Geleta, A. - Blecha, Jan - Endaya, B. - Werner, L. - Černý, Jiří - Zobalová, Renata - Goodwin, J. - Špaček, Tomáš - Pesdar, E.A. - Yan, B. - Nguyen, M.N. - Vondrusová, Magdaléna - Sobol, Margaryta - Ježek, Petr - Hozák, Pavel - Truksa, Jaroslav - Rohlena, Jakub - Dong, L.F. - Neužil, Jiří
Selective Disruption of Respiratory Supercomplexes as a New Strategy to Suppress Her2(high) Breast Cancer.
Antioxidants & Redox Signaling. Roč. 26, č. 2 (2017), s. 84-103. ISSN 1523-0864. E-ISSN 1557-7716
R&D Projects: GA ČR(CZ) GA16-12719S; GA ČR(CZ) GA16-22823S; GA ČR GA13-28830S; GA ČR(CZ) GA16-12816S; GA TA ČR(CZ) TE01020118; GA MPO FR-TI3/588; GA MŠMT(CZ) LQ1604; GA MŠMT(CZ) ED1.1.00/02.0109
Institutional support: RVO:86652036 ; RVO:67985823 ; RVO:68378050
Keywords : mitochondrially targeted tamoxifen * HER2 * respirasome
OECD category: Biochemistry and molecular biology; Oncology (FGU-C); Biochemistry and molecular biology (UMG-J)
Impact factor: 6.530, year: 2017
Permanent Link: http://hdl.handle.net/11104/0270919 - 8.0462874 - FGÚ 2017 RIV DE eng J - Journal Article
Alán, Lukáš - Špaček, Tomáš - Ježek, Petr
Delaunay algorithm and principal component analysis for 3D visualization of mitochondrial DNA nucleoids by Biplane FPALM/dSTORM.
European Biophysics Journal With Biophysics Letters. Roč. 45, č. 5 (2016), s. 443-461. ISSN 0175-7571. E-ISSN 1432-1017
R&D Projects: GA ČR(CZ) GA13-02033S; GA MŠMT(CZ) ED1.1.00/02.0109
Institutional support: RVO:67985823
Keywords : 3D object segmentation * Delaunay algorithm * principal component analysis * 3D super-resolution microscopy * nucleoids * mitochondrial DNA replication
Subject RIV: BO - Biophysics
Impact factor: 1.472, year: 2016
Permanent Link: http://hdl.handle.net/11104/0262234 - 9.0462870 - FGÚ 2017 RIV US eng J - Journal Article
Alán, Lukáš - Špaček, Tomáš - Pajuelo-Reguera, David - Jabůrek, Martin - Ježek, Petr
Mitochondrial nucleoid clusters protect newly synthesized mtDNA during Doxorubicin- and Ethidium Bromide-induced mitochondrial stress.
Toxicology and Applied Pharmacology. Roč. 302, Jul 1 (2016), s. 31-40. ISSN 0041-008X. E-ISSN 1096-0333
R&D Projects: GA ČR(CZ) GAP305/12/1247; GA MŠMT(CZ) LQ1604; GA MŠMT(CZ) ED1.1.00/02.0109
Institutional support: RVO:67985823
Keywords : Doxorubicin * Ethidium Bromide * nucleoid clusters * mitochondrial DNA stress * mitochondrial transcription factor A
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 3.791, year: 2016
Permanent Link: http://hdl.handle.net/11104/0262233 - 10.0459830 - FGÚ 2017 RIV US eng J - Journal Article
Plecitá-Hlavatá, Lydie - Engstová, Hana - Alán, Lukáš - Špaček, Tomáš - Dlasková, Andrea - Smolková, Katarína - Špačková, Jitka - Tauber, Jan - Strádalová, Vendula - Malínský, Jan - Lessard, M. - Bewersdorf, J. - Ježek, Petr
Hypoxic HepG2 cell adaptation decreases ATP synthase dimers and ATP production in inflated cristae by mitofilin down-regulation concomitant to MICOS clustering.
FASEB Journal. Roč. 30, č. 5 (2016), s. 1941-1957. ISSN 0892-6638. E-ISSN 1530-6860
R&D Projects: GA ČR(CZ) GA13-02033S; GA ČR GJ15-02022Y
Institutional support: RVO:67985823 ; RVO:68378041
Keywords : Mitofilin * Mic60 * OPA1 * dSTORM * 3D immunocytochemistry * electron microscopy * mitochondrial cristae morphology
Subject RIV: EA - Cell Biology
Impact factor: 5.498, year: 2016
Permanent Link: http://hdl.handle.net/11104/0259995