Search results
- 1.0495507 - ÚMG 2019 RIV FR eng J - Journal Article
von Morgen, Patrick - Liďák, Tomáš - Hořejší, Zuzana - Macůrek, Libor
Nuclear localisation of 53BP1 is regulated by phosphorylation of the nuclear localisation signal.
Biology of the Cell. Roč. 110, č. 6 (2018), s. 137-146. ISSN 0248-4900. E-ISSN 1768-322X
R&D Projects: GA MŠMT LO1220
Institutional support: RVO:68378050
Keywords : DNA damage * repair * Intracellular compartmentalisation * Post-translational modification
OECD category: Biochemistry and molecular biology
Impact factor: 3.863, year: 2018
Permanent Link: http://hdl.handle.net/11104/0288475 - 2.0488090 - ÚMG 2018 RIV US eng J - Journal Article
Malinová, Anna - Cvačková, Zuzana - Matějů, Daniel - Hořejší, Zuzana - Abeza, C. - Vandermoere, F. - Bertrand, E. - Staněk, David - Verheggen, C.
Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.
Journal of Cell Biology. Roč. 216, č. 6 (2017), s. 1579-1596. ISSN 0021-9525. E-ISSN 1540-8140
R&D Projects: GA ČR GPP301/12/P425; GA ČR GA15-00790S; GA ČR(CZ) GA14-34264S; GA MŠMT LO1419
Institutional support: RVO:68378050
Keywords : dominant retinitis-pigmentosa * splicing factor prp8 * rna-polymerase-ii * structural basis * spliceosomal snrnps * coiled bodies * cajal bodies * r2tp complex * mutations * biogenesis
OECD category: Biochemistry and molecular biology
Impact factor: 8.784, year: 2017
Permanent Link: http://hdl.handle.net/11104/0282716File Download Size Commentary Version Access J_Cell_Biology_A_Malinova_2017.pdf 2 3 MB Publisher’s postprint require - 3.0487326 - ÚMG 2018 RIV GB eng J - Journal Article
von Morgen, Patrick - Burdová, Kamila - Flower, T.G. - O'Reilly, N.J. - Boulton, S.J. - Smerdon, S.J. - Macůrek, Libor - Hořejší, Zuzana
MRE11 stability is regulated by CK2-dependent interaction with R2TP complex.
Oncogene. Roč. 36, č. 34 (2017), s. 4943-4950. ISSN 0950-9232. E-ISSN 1476-5594
R&D Projects: GA ČR(CZ) GA14-34264S
Institutional support: RVO:68378050
Keywords : strand break repair * telangiectasia-like disorder * rna-polymerase-ii * clinical presentation * dna adducts * phosphorylation * hsp90 * protein * cancer * cochaperone
OECD category: Biochemistry and molecular biology
Impact factor: 6.854, year: 2017
Permanent Link: http://hdl.handle.net/11104/0281975File Download Size Commentary Version Access Oncogene_P_von_Morgen_2017.pdf 15 1 MB Author’s postprint require - 4.0442681 - ÚMG 2015 RIV CH eng J - Journal Article
von Morgen, Patrick - Hořejší, Zuzana - Macůrek, Libor
Substrate recognition and function of the R2TP complex in response to cellular stress.
Frontiers in genetics. Roč. 6, February 2015 (2015). E-ISSN 1664-8021
R&D Projects: GA ČR(CZ) GA14-34264S; GA MŠMT LO1220
Institutional support: RVO:68378050
Keywords : R2TPcomplex * proteinfolding * DNAdamageresponse
Subject RIV: EB - Genetics ; Molecular Biology
Permanent Link: http://hdl.handle.net/11104/0245494 - 5.0333900 - ÚMG 2010 RIV GB eng J - Journal Article
Nováková, Zora - Hubáčková, Soňa - Košař, Martin - Janderová-Rossmeislová, Lenka - Dobrovolná, Jana - Vašicová, Pavla - Vančurová, Markéta - Hořejší, Zuzana - Hozák, Pavel - Bártek, Jiří - Hodný, Zdeněk
Cytokine expression and signaling in drug-induced cellular senescence.
Oncogene. Roč. 29, č. 2 (2010), s. 273-284. ISSN 0950-9232. E-ISSN 1476-5594
R&D Projects: GA AV ČR IAA500390501; GA ČR GA204/08/1418; GA MŠMT LC545
Grant - others:EC(XE) TRIREME
Institutional research plan: CEZ:AV0Z50520514; CEZ:AV0Z50200510
Keywords : cellular senescence * cytokines * JAK/STAT signaling pathway
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 7.414, year: 2010
Permanent Link: http://hdl.handle.net/11104/0178775File Download Size Commentary Version Access 0333900.pdf 3 773.3 KB Publisher’s postprint require 0333900.pdf 7 845.1 KB Publisher’s postprint require - 6.0108982 - UMG-J 20043204 RIV GB eng J - Journal Article
Pajer, Petr - Pečenka, Vladimír - Karafiát, Vít - Králová, Jarmila - Hořejší, Zuzana - Dvořák, Michal
The twist gene is a common target of retroviral integration and transcriptional deregulation in experimental nephroblastoma.
[Gen twist je běžným cílem integrace retrovirů a transkripční deregulace u experimentálních nefroblastomů.]
Oncogene. Roč. 22, č. 5 (2003), s. 665-673. ISSN 0950-9232. E-ISSN 1476-5594
R&D Projects: GA ČR GV301/98/K042; GA ČR GA204/00/0554
Institutional research plan: CEZ:AV0Z5052915
Keywords : twist gene * MAV retrovirus * nephroblastoma
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 6.495, year: 2003
Permanent Link: http://hdl.handle.net/11104/0016096 - 7.0098551 - ÚMG 2008 RIV GB eng J - Journal Article
Bartkova, J. - Hořejší, Zuzana - Sehested, M. - Nesland, J.M. - Rajpert-De Meyts, E. - Skakkebaek, N.E. - Stucki, M. - Jackson, S. - Lukas, J. - Bártek, Jiří
DNA damage response mediators MDC1 and 53BP1: constitutive activation and aberrant loss in breast and lung cancer, but not in testicular germ cell tumours.
[Zprostředkovatelé odpovědi na poškození DNA MDC1 a 53BP1: konstitutivní aktivace nebo anomální absence v nádorech prsu a plic, nikoli však v nádorech testikulárních zárodečných buněk.]
Oncogene. Roč. 26, č. 53 (2007), s. 7414-7422. ISSN 0950-9232. E-ISSN 1476-5594
Institutional research plan: CEZ:AV0Z50520514
Keywords : DNA damage response * cancer * MDC1 and 53BP1 defects * tumour suppressors
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 6.440, year: 2007
Permanent Link: http://hdl.handle.net/11104/0157429 - 8.0027591 - ÚMG 2006 RIV GB eng J - Journal Article
Bartkova, J. - Hořejší, Zuzana - Koed, K. - Krämer, A. - Tort, F. - Zieger, K. - Guldberg, P. - Sehested, M. - Nesland, J.M. - Lukas, C. - Orntoft, T. - Lukas, J. - Bartek, J.
DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis.
[Buněčné mechanizmy odpovídající na poškození DNA jako možná bariéra časné nádorové transformace lidských buněk.]
Nature. Roč. 434, č. 7035 (2005), s. 864-870. ISSN 0028-0836. E-ISSN 1476-4687
Institutional research plan: CEZ:AV0Z50520514; CEZ:AV0Z5052915
Keywords : DNA damage * cancer
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 29.273, year: 2005
Permanent Link: http://hdl.handle.net/11104/0117679 - 9.0000242 - ÚMG 2005 GB eng J - Journal Article
Hořejší, Zuzana - Falck, J. - Bakkenist, C.J. - Kastan, M.B. - Lukas, J. - Bartek, J.
Distinct functional domains of Nbs1 modulate the timing and magnitude of ATM activation after low doses of ionizing radiation.
[Různé fukční domény Nbs1 modulují časování a sílu aktivace ATM po ionizačním ozáření nízkými dávkami.]
Oncogene. Roč. 23, č. 17 (2004), s. 3122-3127. ISSN 0950-9232. E-ISSN 1476-5594
Grant - others:NIH(US) CA 71387; NIH(US) CA 21765
Keywords : Nbs1 * ATM * DNA damage
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 6.318, year: 2004
Permanent Link: http://hdl.handle.net/11104/0017521