Search results

  1. 1.
    0495507 - ÚMG 2019 RIV FR eng J - Journal Article
    von Morgen, Patrick - Liďák, Tomáš - Hořejší, Zuzana - Macůrek, Libor
    Nuclear localisation of 53BP1 is regulated by phosphorylation of the nuclear localisation signal.
    Biology of the Cell. Roč. 110, č. 6 (2018), s. 137-146. ISSN 0248-4900. E-ISSN 1768-322X
    R&D Projects: GA MŠMT LO1220
    Institutional support: RVO:68378050
    Keywords : DNA damage * repair * Intracellular compartmentalisation * Post-translational modification
    OECD category: Biochemistry and molecular biology
    Impact factor: 3.863, year: 2018
    Permanent Link: http://hdl.handle.net/11104/0288475
     
     
  2. 2.
    0488090 - ÚMG 2018 RIV US eng J - Journal Article
    Malinová, Anna - Cvačková, Zuzana - Matějů, Daniel - Hořejší, Zuzana - Abeza, C. - Vandermoere, F. - Bertrand, E. - Staněk, David - Verheggen, C.
    Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.
    Journal of Cell Biology. Roč. 216, č. 6 (2017), s. 1579-1596. ISSN 0021-9525. E-ISSN 1540-8140
    R&D Projects: GA ČR GPP301/12/P425; GA ČR GA15-00790S; GA ČR(CZ) GA14-34264S; GA MŠMT LO1419
    Institutional support: RVO:68378050
    Keywords : dominant retinitis-pigmentosa * splicing factor prp8 * rna-polymerase-ii * structural basis * spliceosomal snrnps * coiled bodies * cajal bodies * r2tp complex * mutations * biogenesis
    OECD category: Biochemistry and molecular biology
    Impact factor: 8.784, year: 2017
    Permanent Link: http://hdl.handle.net/11104/0282716
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    J_Cell_Biology_A_Malinova_2017.pdf23 MBPublisher’s postprintrequire
     
     
  3. 3.
    0487326 - ÚMG 2018 RIV GB eng J - Journal Article
    von Morgen, Patrick - Burdová, Kamila - Flower, T.G. - O'Reilly, N.J. - Boulton, S.J. - Smerdon, S.J. - Macůrek, Libor - Hořejší, Zuzana
    MRE11 stability is regulated by CK2-dependent interaction with R2TP complex.
    Oncogene. Roč. 36, č. 34 (2017), s. 4943-4950. ISSN 0950-9232. E-ISSN 1476-5594
    R&D Projects: GA ČR(CZ) GA14-34264S
    Institutional support: RVO:68378050
    Keywords : strand break repair * telangiectasia-like disorder * rna-polymerase-ii * clinical presentation * dna adducts * phosphorylation * hsp90 * protein * cancer * cochaperone
    OECD category: Biochemistry and molecular biology
    Impact factor: 6.854, year: 2017
    Permanent Link: http://hdl.handle.net/11104/0281975
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    Oncogene_P_von_Morgen_2017.pdf151 MBAuthor’s postprintrequire
     
     
  4. 4.
    0442681 - ÚMG 2015 RIV CH eng J - Journal Article
    von Morgen, Patrick - Hořejší, Zuzana - Macůrek, Libor
    Substrate recognition and function of the R2TP complex in response to cellular stress.
    Frontiers in genetics. Roč. 6, February 2015 (2015). E-ISSN 1664-8021
    R&D Projects: GA ČR(CZ) GA14-34264S; GA MŠMT LO1220
    Institutional support: RVO:68378050
    Keywords : R2TPcomplex * proteinfolding * DNAdamageresponse
    Subject RIV: EB - Genetics ; Molecular Biology
    Permanent Link: http://hdl.handle.net/11104/0245494
     
     
  5. 5.
    0333900 - ÚMG 2010 RIV GB eng J - Journal Article
    Nováková, Zora - Hubáčková, Soňa - Košař, Martin - Janderová-Rossmeislová, Lenka - Dobrovolná, Jana - Vašicová, Pavla - Vančurová, Markéta - Hořejší, Zuzana - Hozák, Pavel - Bártek, Jiří - Hodný, Zdeněk
    Cytokine expression and signaling in drug-induced cellular senescence.
    Oncogene. Roč. 29, č. 2 (2010), s. 273-284. ISSN 0950-9232. E-ISSN 1476-5594
    R&D Projects: GA AV ČR IAA500390501; GA ČR GA204/08/1418; GA MŠMT LC545
    Grant - others:EC(XE) TRIREME
    Institutional research plan: CEZ:AV0Z50520514; CEZ:AV0Z50200510
    Keywords : cellular senescence * cytokines * JAK/STAT signaling pathway
    Subject RIV: EB - Genetics ; Molecular Biology
    Impact factor: 7.414, year: 2010
    Permanent Link: http://hdl.handle.net/11104/0178775
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    0333900.pdf3773.3 KBPublisher’s postprintrequire
    0333900.pdf7845.1 KBPublisher’s postprintrequire
     
     
  6. 6.
    0108982 - UMG-J 20043204 RIV GB eng J - Journal Article
    Pajer, Petr - Pečenka, Vladimír - Karafiát, Vít - Králová, Jarmila - Hořejší, Zuzana - Dvořák, Michal
    The twist gene is a common target of retroviral integration and transcriptional deregulation in experimental nephroblastoma.
    [Gen twist je běžným cílem integrace retrovirů a transkripční deregulace u experimentálních nefroblastomů.]
    Oncogene. Roč. 22, č. 5 (2003), s. 665-673. ISSN 0950-9232. E-ISSN 1476-5594
    R&D Projects: GA ČR GV301/98/K042; GA ČR GA204/00/0554
    Institutional research plan: CEZ:AV0Z5052915
    Keywords : twist gene * MAV retrovirus * nephroblastoma
    Subject RIV: EB - Genetics ; Molecular Biology
    Impact factor: 6.495, year: 2003
    Permanent Link: http://hdl.handle.net/11104/0016096
     
     
  7. 7.
    0098551 - ÚMG 2008 RIV GB eng J - Journal Article
    Bartkova, J. - Hořejší, Zuzana - Sehested, M. - Nesland, J.M. - Rajpert-De Meyts, E. - Skakkebaek, N.E. - Stucki, M. - Jackson, S. - Lukas, J. - Bártek, Jiří
    DNA damage response mediators MDC1 and 53BP1: constitutive activation and aberrant loss in breast and lung cancer, but not in testicular germ cell tumours.
    [Zprostředkovatelé odpovědi na poškození DNA MDC1 a 53BP1: konstitutivní aktivace nebo anomální absence v nádorech prsu a plic, nikoli však v nádorech testikulárních zárodečných buněk.]
    Oncogene. Roč. 26, č. 53 (2007), s. 7414-7422. ISSN 0950-9232. E-ISSN 1476-5594
    Institutional research plan: CEZ:AV0Z50520514
    Keywords : DNA damage response * cancer * MDC1 and 53BP1 defects * tumour suppressors
    Subject RIV: EB - Genetics ; Molecular Biology
    Impact factor: 6.440, year: 2007
    Permanent Link: http://hdl.handle.net/11104/0157429
     
     
  8. 8.
    0027591 - ÚMG 2006 RIV GB eng J - Journal Article
    Bartkova, J. - Hořejší, Zuzana - Koed, K. - Krämer, A. - Tort, F. - Zieger, K. - Guldberg, P. - Sehested, M. - Nesland, J.M. - Lukas, C. - Orntoft, T. - Lukas, J. - Bartek, J.
    DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis.
    [Buněčné mechanizmy odpovídající na poškození DNA jako možná bariéra časné nádorové transformace lidských buněk.]
    Nature. Roč. 434, č. 7035 (2005), s. 864-870. ISSN 0028-0836. E-ISSN 1476-4687
    Institutional research plan: CEZ:AV0Z50520514; CEZ:AV0Z5052915
    Keywords : DNA damage * cancer
    Subject RIV: EB - Genetics ; Molecular Biology
    Impact factor: 29.273, year: 2005
    Permanent Link: http://hdl.handle.net/11104/0117679
     
     
  9. 9.
    0000242 - ÚMG 2005 GB eng J - Journal Article
    Hořejší, Zuzana - Falck, J. - Bakkenist, C.J. - Kastan, M.B. - Lukas, J. - Bartek, J.
    Distinct functional domains of Nbs1 modulate the timing and magnitude of ATM activation after low doses of ionizing radiation.
    [Různé fukční domény Nbs1 modulují časování a sílu aktivace ATM po ionizačním ozáření nízkými dávkami.]
    Oncogene. Roč. 23, č. 17 (2004), s. 3122-3127. ISSN 0950-9232. E-ISSN 1476-5594
    Grant - others:NIH(US) CA 71387; NIH(US) CA 21765
    Keywords : Nbs1 * ATM * DNA damage
    Subject RIV: EB - Genetics ; Molecular Biology
    Impact factor: 6.318, year: 2004
    Permanent Link: http://hdl.handle.net/11104/0017521
     
     


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