Search results
- 1.0586165 - ÚOCHB 2025 RIV CZ cze J - Journal Article
Turnovská, Tereza - Jiráček, Jiří - Žáková, Lenka
IGF2: OPOMÍJENÝ HORMON Z RODINY INZULINU S VÝZNAMNÝM TERAPEUTICKÝM POTENCIÁLEM.
[IGF2: A NEGLECTED HORMONE OF THE INSULIN FAMILY WITH SIGNIFICANT THERAPEUTIC POTENTIAL.]
Chemické listy. Roč. 118, č. 6 (2024), s. 321-330. ISSN 0009-2770. E-ISSN 1213-7103
R&D Projects: GA ČR(CZ) GA23-05805S; GA MŠMT(CZ) LX22NPO5104
Institutional support: RVO:61388963
Keywords : IGF2 * insulin * insulin receptor * IGF2 receptor * carcinogenesis * neurodegenerative diseases * embryogenesis
Impact factor: 0.6, year: 2022
Method of publishing: Open access
https://doi.org/10.54779/chl20240321
Permanent Link: https://hdl.handle.net/11104/0353751File Download Size Commentary Version Access 10.54779chl20240321.pdf 0 1.3 MB Publisher’s postprint open-access - 2.0581691 - ÚOCHB 2025 RIV NL eng J - Journal Article
Chrudinová, M. - Kirk, N. S. - Chuard, A. - Venugopal, H. - Zhang, F. - Lubos, Marta - Gelfanov, V. - Páníková, Terezie - Žáková, Lenka - Cutone, J. - Mojares, M. - DiMarchi, R. - Jiráček, Jiří - Altindis, E.
A viral insulin-like peptide inhibits IGF-1 receptor phosphorylation and regulates IGF1R gene expression.
Molecular Metabolism. Roč. 80, February (2024), č. článku 101863. ISSN 2212-8778. E-ISSN 2212-8778
R&D Projects: GA MŠMT(CZ) LX22NPO5104
Institutional support: RVO:61388963
Keywords : viral insulin/IGF-1 like peptides (VILPs) * IGF-1 * insulin * IGF1 receptor * IGF1 receptor inhibition * biased signaling * Iridoviridae
OECD category: Biochemistry and molecular biology
Impact factor: 8.1, year: 2022
Method of publishing: Open access
https://doi.org/10.1016/j.molmet.2023.101863
Permanent Link: https://hdl.handle.net/11104/0349880File Download Size Commentary Version Access 10.1016j.molmet.2023.101863.pdf 1 4 MB Publisher’s postprint open-access - 3.0577780 - ÚOCHB 2024 RIV GB eng J - Journal Article
Kertisová, Anna - Žáková, Lenka - Macháčková, Kateřina - Marek, Aleš - Šácha, Pavel - Pompach, Petr - Jiráček, Jiří - Selicharová, Irena
Insulin receptor Arg717 and IGF-1 receptor Arg704 play a key role in ligand binding and in receptor activation.
Open Biology. Roč. 13, č. 11 (2023), č. článku 230142. E-ISSN 2046-2441
R&D Projects: GA MŠMT(CZ) LX22NPO5104; GA MŠMT(CZ) EF16_019/0000729; GA ČR(CZ) GA22-17978S; GA MŠMT(CZ) EF18_046/0015974; GA MŠMT LM2023042
Institutional support: RVO:61388963 ; RVO:86652036
Keywords : mutagenesisin vitro * peptide hormone * eceptor modification * eceptor tyrosine kinase * structure–function
OECD category: Biochemistry and molecular biology
Impact factor: 5.8, year: 2022
Method of publishing: Open access
https://doi.org/10.1098/rsob.230142
Permanent Link: https://hdl.handle.net/11104/0346886File Download Size Commentary Version Access 10.1098rsob.230142.pdf 2 2 MB Publisher’s postprint open-access - 4.0574400 - ÚOCHB 2024 RIV GB eng J - Journal Article
Potalitsyn, Pavlo - Mrázková, Lucie - Selicharová, Irena - Tencerová, Michaela - Ferenčáková, Michaela - Chrudinová, Martina - Turnovská, Tereza - Brzozowski, A. M. - Marek, Aleš - Kaminský, Jakub - Jiráček, Jiří - Žáková, Lenka
Non-glycosylated IGF2 prohormones are more mitogenic than native IGF2.
Communications Biology. Roč. 6, č. 1 (2023), č. článku 863. E-ISSN 2399-3642
R&D Projects: GA ČR(CZ) GA19-14069S; GA MŠMT(CZ) EF16_019/0000729; GA MŠMT(CZ) LX22NPO5104
Institutional support: RVO:61388963 ; RVO:67985823
Keywords : hormone * prohormone * precursor * mitogenic * receptor * IGF
OECD category: Biochemistry and molecular biology
Impact factor: 5.9, year: 2022
Method of publishing: Open access
https://doi.org/10.1038/s42003-023-05239-6
Permanent Link: https://hdl.handle.net/11104/0344735File Download Size Commentary Version Access 10.1038s42003-023-05239-6.pdf 1 2.1 MB Publisher’s postprint open-access - 5.0567614 - ÚOCHB 2024 RIV GB eng J - Journal Article
Lubos, Marta - Pícha, Jan - Selicharová, Irena - Žák, Jiří - Buděšínský, Miloš - Mitrová, Katarína - Žáková, Lenka - Jiráček, Jiří
Modulation of the antagonistic properties of an insulin mimetic peptide by disulfide bridge modifications.
Journal of Peptide Science. Roč. 29, č. 7 (2023), č. článku e3478. ISSN 1075-2617. E-ISSN 1099-1387
R&D Projects: GA MŠMT(CZ) LX22NPO5104; GA MŠMT(CZ) EF16_019/0000729
Institutional support: RVO:61388963
Keywords : antagonism * dicarba * disulfide mimetics * insulin mimetic peptide * insulin receptor * staple * triazole
OECD category: Biochemistry and molecular biology
Impact factor: 2.1, year: 2022
Method of publishing: Open access
https://doi.org/10.1002/psc.3478
Permanent Link: https://hdl.handle.net/11104/0338851File Download Size Commentary Version Access 10.1002psc.3478.pdf 2 1.1 MB Publisher’s postprint open-access - 6.0566032 - ÚOCHB 2023 RIV GB eng J - Journal Article
Asai, Seiya - Moravcová, J. - Žáková, Lenka - Selicharová, Irena - Hadravová, Romana - Brzozowski, A. M. - Nováček, J. - Jiráček, Jiří
Characterization of insulin crystalline form in isolated β-cell secretory granules.
Open Biology. Roč. 12, č. 12 (2022), č. článku 220322. E-ISSN 2046-2441
R&D Projects: GA MŠMT(CZ) EF16_019/0000729
Research Infrastructure: CIISB II - 90127
Institutional support: RVO:61388963
Keywords : insulin secretory granules * protein crystals * in vivo crystalization * cryo-EM
OECD category: Cell biology
Impact factor: 5.8, year: 2022
Method of publishing: Open access
https://doi.org/10.1098/rsob.220322
Permanent Link: https://hdl.handle.net/11104/0337471 - 7.0556184 - ÚOCHB 2023 RIV GB eng J - Journal Article
Lubos, Marta - Mrázková, Lucie - Gwozdiaková, Petra - Pícha, Jan - Buděšínský, Miloš - Jiráček, Jiří - Kaminský, Jakub - Žáková, Lenka
Functional stapled fragments of human preptin of minimised length.
Organic & Biomolecular Chemistry. Roč. 20, č. 12 (2022), s. 2446-2454. ISSN 1477-0520. E-ISSN 1477-0539
R&D Projects: GA ČR(CZ) GA19-14069S; GA MŠMT(CZ) EF16_019/0000729; GA MŠMT LTAUSA18085
Research Infrastructure: e-INFRA CZ - 90140
Institutional support: RVO:61388963
Keywords : alpha-helical peptides * secondary structure * force field
OECD category: Biochemistry and molecular biology
Impact factor: 3.2, year: 2022
Method of publishing: Limited access
https://doi.org/10.1039/D1OB02193A
Permanent Link: http://hdl.handle.net/11104/0331047 - 8.0546413 - ÚOCHB 2022 RIV US eng J - Journal Article
Páníková, Terezie - Mitrová, Katarína - Halamová, Tereza - Mrzílková, Karolína - Pícha, Jan - Chrudinová, Martina - Kurochka, Andrii - Selicharová, Irena - Žáková, Lenka - Jiráček, Jiří
Insulin Analogues with Altered Insulin Receptor Isoform Binding Specificities and Enhanced Aggregation Stabilities.
Journal of Medicinal Chemistry. Roč. 64, č. 19 (2021), s. 14848-14859. ISSN 0022-2623. E-ISSN 1520-4804
R&D Projects: GA MŠMT(CZ) EF16_019/0000729
Institutional support: RVO:61388963
Keywords : insulin * hepatoselective * stability
OECD category: Medicinal chemistry
Impact factor: 8.039, year: 2021
Method of publishing: Limited access
https://doi.org/10.1021/acs.jmedchem.1c01388
Permanent Link: http://hdl.handle.net/11104/0322932 - 9.0543107 - ÚOCHB 2022 RIV DE eng J - Journal Article
Asai, Seiya - Žáková, Lenka - Selicharová, Irena - Marek, Aleš - Jiráček, Jiří
A radioligand receptor binding assay for measuring of insulin secreted by MIN6 cells after stimulation with glucose, arginine, ornithine, dopamine, and serotonin.
Analytical and Bioanalytical Chemistry. Roč. 413, č. 17 (2021), s. 4531-4543. ISSN 1618-2642. E-ISSN 1618-2650
R&D Projects: GA MŠMT(CZ) EF16_019/0000729
Institutional support: RVO:61388963
Keywords : binding assay * insulin receptor * insulin secretion * radioligand * secretagogue * β Cells
OECD category: Biochemistry and molecular biology
Impact factor: 4.478, year: 2021
Method of publishing: Limited access
https://doi.org/10.1007/s00216-021-03423-3
Permanent Link: http://hdl.handle.net/11104/0320393 - 10.0538777 - ÚOCHB 2022 RIV NL eng J - Journal Article
Chrudinová, M. - Moreau, F. - Lim Noh, H. - Páníková, Terezie - Žáková, Lenka - Friedline, R. H. - Valenzuela, F. A. - Kim, J. K. - Jiráček, Jiří - Kahn, C. R. - Altindis, E.
Characterization of viral insulins reveals white adipose tissue-specific effects in mice.
Molecular Metabolism. Roč. 44, Feb (2021), č. článku 101121. ISSN 2212-8778. E-ISSN 2212-8778
Institutional support: RVO:61388963
Keywords : viral insulin * adipose tissue * receptor * binding
OECD category: Biochemistry and molecular biology
Impact factor: 8.568, year: 2021
Method of publishing: Open access
https://doi.org/10.1016/j.molmet.2020.101121
Permanent Link: http://hdl.handle.net/11104/0316957