Search results
- 1.0561378 - ÚMG 2023 RIV CH eng J - Článek v odborném periodiku
Švec, Jiří - Šťastná, Monika - Janečková, Lucie - Hrčkulák, Dušan - Vojtěchová, Martina - Onhajzer, Jakub - Kříž, Vítězslav - Galušková, Kateřina - Šloncová, Eva - Kubovčiak, Jan - Pfeiferová, Lucie - Hrudka, J. - Matěj, R. - Waldauf, P. - Havluj, L. - Kolář, Michal - Kořínek, Vladimír
TROP2 Represents a Negative Prognostic Factor in Colorectal Adenocarcinoma and Its Expression Is Associated with Features of Epithelial-Mesenchymal Transition and Invasiveness.
Cancers (Basel). Roč. 14, č. 17 (2022), č. článku 4137. E-ISSN 2072-6694
Grant CEP: GA ČR(CZ) GA18-26324S; GA MŠMT LX22NPO5102; GA MŠMT(CZ) LM2018129; GA MŠMT(CZ) EF16_019/0000785
Institucionální podpora: RVO:68378050
Klíčová slova: apc * colorectal cancer * emt * expression profiling * organoids * tacstd2 * WNT/beta-catenin signaling
Obor OECD: Oncology
Impakt faktor: 5.2, rok: 2022
Způsob publikování: Open access
https://doi.org/10.3390/cancers14174137
Trvalý link: https://hdl.handle.net/11104/0338612File Download Size Commentary Version Access cancers-14-04137.pdf 0 8.6 MB Publisher’s postprint open-access - 2.0508788 - ÚMG 2020 RIV GB eng J - Journal Article
Horázná, Monika - Janečková, Lucie - Švec, Jiří - Babošová, Oľga - Hrčkulák, Dušan - Vojtěchová, Martina - Galušková, Kateřina - Šloncová, Eva - Kolář, Michal - Strnad, Hynek - Kořínek, Vladimír
Msx1 loss suppresses formation of the ectopic crypts developed in the Apc-deficient small intestinal epithelium.
Scientific Reports. Roč. 9, č. 1 (2019), č. článku 1629. ISSN 2045-2322. E-ISSN 2045-2322
R&D Projects: GA ČR GA15-25100S; GA MŠMT LO1419; GA MŠMT(CZ) LM2015040; GA MŠMT(CZ) LM2015062; GA MŠMT LO1220; GA MŠMT ED2.1.00/19.0395
Institutional support: RVO:68378050
Keywords : human colon * stem-cells * gene * expression * adenoma * growth * differentiation * adenocarcinoma * identification * transformation
OECD category: Cell biology
Impact factor: 3.998, year: 2019
Method of publishing: Open access
https://www.nature.com/articles/s41598-018-38310-y
Permanent Link: http://hdl.handle.net/11104/0305732File Download Size Commentary Version Access Scientific_Reports_M_Horazna_2019.pdf 4 7.3 MB Publisher’s postprint require - 3.0507870 - ÚMG 2020 RIV CH eng J - Journal Article
Janečková, Lucie - Kostovčíková, Klára - Švec, Jiří - Šťastná, Monika - Strnad, Hynek - Kolář, Michal - Hudcovič, T. - Stančíková, Jitka - Turečková, Jolana - Baloghová, Nikol - Šloncová, Eva - Galušková, Kateřina - Tlaskalová-Hogenová, H. - Kořínek, Vladimír
Unique Gene Expression Signatures in the Intestinal Mucosa and Organoids Derived from Germ-Free and Monoassociated Mice.
International Journal of Molecular Sciences. Roč. 20, č. 7 (2019), č. článku 1581. E-ISSN 1422-0067
R&D Projects: GA ČR(CZ) GA16-06326S; GA MŠMT LO1419
Institutional support: RVO:68378050
Keywords : expression profiling * Enricher tool * microbiota * monoassociation * Onecut2
OECD category: Biochemistry and molecular biology
Impact factor: 4.556, year: 2019
Method of publishing: Open access
https://www.mdpi.com/1422-0067/20/7/1581
Permanent Link: http://hdl.handle.net/11104/0305733 - 4.0500434 - ÚMG 2019 RIV CH eng J - Journal Article
Hrčkulák, Dušan - Janečková, Lucie - Láníková, Lucie - Kříž, Vítězslav - Horázná, Monika - Babošová, Oľga - Vojtěchová, Martina - Galušková, Kateřina - Šloncová, Eva - Kořínek, Vladimír
Wnt Effector TCF4 Is Dispensable for Wnt Signaling in Human Cancer Cells.
Genes. Roč. 9, č. 9 (2018), č. článku 439. E-ISSN 2073-4425
R&D Projects: GA ČR GA15-25100S; GA MŠMT LO1419; GA MŠMT(CZ) LM2015040; GA MŠMT(CZ) LM2015062
Institutional support: RVO:68378050
Keywords : colorectal cancer * conditional gene inactivation * epithelium * gut * organoids * tcf7l2 * tumorigenesis * Wnt signaling
OECD category: Biochemistry and molecular biology
Impact factor: 3.331, year: 2018
Permanent Link: http://hdl.handle.net/11104/0292514File Download Size Commentary Version Access Genes_D_Hrckulak_2018.pdf 1 2.9 MB Publisher’s postprint require - 5.0472044 - ÚMG 2017 RIV US eng J - Journal Article
Janečková, Lucie - Kolář, Michal - Švec, Jiří - Láníková, Lucie - Pospíchalová, Vendula - Baloghová, Nikol - Vojtěchová, Martina - Šloncová, Eva - Strnad, Hynek - Kořínek, Vladimír
HIC1 Expression Distinguishes Intestinal Carcinomas Sensitive to Chemotherapy.
Translational Oncology. Roč. 9, č. 2 (2016), s. 99-107. ISSN 1944-7124. E-ISSN 1936-5233
R&D Projects: GA ČR GAP305/12/2347; GA MŠMT LO1419; GA MŠMT(CZ) ED1.1.00/02.0109
Institutional support: RVO:68378050
Keywords : direct target gene * cancer 1 hic1 * colorectal-cancer * breast-cancer * lung-cancer * tgf-beta * methylation * hypermethylation * subtypes * cells
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 3.025, year: 2016
Permanent Link: http://hdl.handle.net/11104/0269388 - 6.0457224 - ÚMG 2017 RIV US eng J - Journal Article
Janečková, Lucie - Fafílek, Bohumil - Krausová, Michaela - Horázná, Monika - Vojtěchová, Martina - Alberich-Jorda, Meritxell - Šloncová, Eva - Galušková, Kateřina - Sedláček, Radislav - Anděrová, Miroslava - Kořínek, Vladimír
Wnt signaling inhibition deprives small intestinal stem cells of clonogenic capacity.
Genesis. Roč. 54, č. 3 (2016), s. 101-114. ISSN 1526-954X. E-ISSN 1526-968X
R&D Projects: GA ČR(CZ) GA14-33952S; GA ČR(CZ) GAP303/12/0855; GA MŠMT(CZ) ED1.1.00/02.0109; GA MŠMT LO1220; GA MŠMT LK21307; GA MŠMT(CZ) LM2011032; GA MŠMT EE2.3.30.0027
Institutional support: RVO:68378050 ; RVO:68378041
Keywords : b-catenin * Cre/loxP * gene targeting * gut * Wnt pathway * TCF/LEF transcription factors
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 2.143, year: 2016
Permanent Link: http://hdl.handle.net/11104/0257650 - 7.0455295 - ÚMG 2016 RIV US eng J - Journal Article
Janečková, Lucie - Pospíchalová, Vendula - Fafílek, Bohumil - Vojtěchová, Martina - Turečková, Jolana - Dobeš, Jan - Dubuissez, M. - Leprince, D. - Baloghová, Nikol - Horázná, Monika - Hlavatá, Adéla - Stančíková, Jitka - Šloncová, Eva - Galušková, Kateřina - Strnad, Hynek - Kořínek, Vladimír
HIC1 Tumor Suppressor Loss Potentiates TLR2/NF-kappa B Signaling and Promotes Tissue Damage-Associated Tumorigenesis.
Molecular Cancer Research. Roč. 13, č. 7 (2015), s. 1139-1148. ISSN 1541-7786. E-ISSN 1557-3125
R&D Projects: GA ČR GAP305/12/2347; GA MŠMT(CZ) ED1.1.00/02.0109
Institutional support: RVO:68378050
Keywords : hypermethylated in cancer 1 * intestinal epithelium * colorectal cancer
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 4.510, year: 2015
Permanent Link: http://hdl.handle.net/11104/0255958File Download Size Commentary Version Access Molecular_Cancer_Research_L_Janeckova_2015.pdf 2 1.9 MB Publisher’s postprint require - 8.0435312 - ÚMG 2015 RIV US eng J - Journal Article
Tůmová, Lucie - Pombinho, António R. - Vojtěchová, Martina - Stančíková, Jitka - Gradl, D. - Krausová, Michaela - Šloncová, Eva - Horázná, Monika - Kříž, Vítězslav - Machoňová, Olga - Jindřich, Jindřich - Zdráhal, Z. - Bartůněk, Petr - Kořínek, Vladimír
Monensin Inhibits Canonical Wnt Signaling in Human Colorectal Cancer Cells and Suppresses Tumor Growth in Multiple Intestinal Neoplasia Mice.
Molecular Cancer Therapeutics. Roč. 13, č. 4 (2014), s. 812-822. ISSN 1535-7163. E-ISSN 1538-8514
R&D Projects: GA ČR GAP305/12/2347; GA MPO FR-TI4/802; GA MŠMT LM2011022; GA MŠMT LO1220
Institutional support: RVO:68378050
Keywords : bate-catenin * throughput screen * small molecule inhibitors
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 5.683, year: 2014
Permanent Link: http://hdl.handle.net/11104/0239216File Download Size Commentary Version Access 0435312.pdf 8 2.1 MB Publisher’s postprint require 0435312.pdf 8 2.1 MB Publisher’s postprint require - 9.0386281 - ÚMG 2014 RIV US eng J - Journal Article
Fafílek, Bohumil - Krausová, Michaela - Vojtěchová, Martina - Pospíchalová, Vendula - Tůmová, Lucie - Šloncová, Eva - Huranová, Martina - Stančíková, Jitka - Hlavatá, Adéla - Švec, Jiří - Sedláček, Radislav - Lukšan, O. - Olivierus, M. - Voska, L. - Jirsa, M. - Pačes, Jan - Kolář, Michal - Krivjanská, M. - Klimešová, Klára - Tlaskalová-Hogenová, Helena - Kořínek, Vladimír
Troy, a tumor necrosis factor receptor family member, interacts with Lgr5 to inhibit Wnt signaling in intestinal stem cells.
Gastroenterology. Roč. 144, č. 2 (2013), s. 381-391. ISSN 0016-5085. E-ISSN 1528-0012
R&D Projects: GA MŠMT 2B06077; GA ČR GAP305/11/1780; GA ČR(CZ) GAP304/11/1252; GA ČR(CZ) GD204/09/H058; GA ČR GAP305/10/2143; GA AV ČR KAN200520801
Grant - others:MŠMT(CZ) CZ 1.05/1.1.00/02.0109
Institutional support: RVO:68378050 ; RVO:61388971
Keywords : mouse model of colon cancer * β-catenin * TCF * Tnfrsf19
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 13.926, year: 2013
Permanent Link: http://hdl.handle.net/11104/0216390File Download Size Commentary Version Access 0386281.pdf 8 4.4 MB Publisher’s postprint require - 10.0365113 - ÚMG 2012 RIV US eng J - Journal Article
Pospíchalová, Vendula - Turečková, Jolana - Fafílek, Bohumil - Vojtěchová, Martina - Krausová, Michaela - Lukáš, Jan - Šloncová, Eva - Takacova, S. - Divoký, V. - Leprince, D. - Plachý, Jiří - Kořínek, Vladimír
Generation of two modified mouse alleles of the Hic1 tumor suppressor gene.
Genesis. Roč. 49, č. 3 (2011), s. 142-151. ISSN 1526-954X. E-ISSN 1526-968X
R&D Projects: GA ČR(CZ) GA204/07/1567; GA ČR(CZ) GD204/09/H058
Institutional research plan: CEZ:AV0Z50520514
Keywords : Hypermethylated In Cancer 1 * Hic1 tumor suppressor * gene targeting
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 2.527, year: 2011
Permanent Link: http://hdl.handle.net/11104/0200434File Download Size Commentary Version Access 0365113.pdf 3 1.1 MB Publisher’s postprint require