Search results
- 1.0585467 - MBÚ 2025 RIV NL eng J - Journal Article
Lepesheva, Anna - Grobarčíková, Michaela - Osičková, Adriana - Jurnečka, David - Knoblochová, Šárka - Čížková, Monika - Osička, Radim - Šebo, Peter - Mašín, Jiří
Modification of the RTX domain cap by acyl chains of adapted length rules the formation of functional hemolysin pores.
Biochimica Et Biophysica Acta-Biomembranes. Roč. 1866, č. 5 (2024), s. 184311. ISSN 0005-2736. E-ISSN 1879-2642
R&D Projects: GA ČR(CZ) GA22-15825S; GA ČR(CZ) GA22-01558S; GA ČR(CZ) GX19-27630X; GA MŠMT(CZ) LX22NPO5103; GA MŠMT(CZ) EH22_008/0004597
Research Infrastructure: EATRIS-CZ IV - 90253; CIISB III - 90242
Institutional support: RVO:61388971
Keywords : RTX toxin * Adenylate cyclase toxin * α-Hemolysin * Chimera * Fatty acylation * Cytotoxicity
OECD category: Microbiology
Impact factor: 3.4, year: 2022
Method of publishing: Open access
https://www.sciencedirect.com/science/article/pii/S0005273624000427?via%3Dihub
Permanent Link: https://hdl.handle.net/11104/0353157File Download Size Commentary Version Access Modification of the RTX.pdf 2 3 MB Publisher’s postprint open-access
Research data: the ProteomeXchange Consortium via the PRIDE partner repository with the data set identifier PXD046160 - 2.0579872 - ÚMG 2024 RIV GB eng J - Journal Article
Gruper, Y. - Wolff, A. S. B. - Glanz, L. - Špoutil, František - Marthinussen, M. C. - Osičková, Adriana - Herzig, Y. - Goldfarb, Y. - Aranaz-Novaliches, Gorreti - Dobeš, J. - Kadouri, N. - Ben-Nun, O. - Binyamin, A. - Lavi, B. - Givony, T. - Khalaila, R. - Gome, T. - Wald, Tomáš - Mrázková, Blanka - Sochen, C. - Besnard, M. - Ben-Dor, S. - Feldmesser, E. - Orlova, E. M. - Hegedus, C. - Lampe, I. - Papp, T. - Felszeghy, S. - Sedláček, Radislav - Davidovich, E. - Tal, N. - Shouval, D. S. - Shamir, R. - Guillonneau, C. - Szondy, Z. - Lundin, K. E. A. - Osička, Radim - Procházka, Jan - Husebye, E. S. - Abramson, J.
Autoimmune amelogenesis imperfecta in patients with APS-1 and coeliac disease.
Nature. Roč. 624, č. 7992 (2023), s. 653-662. ISSN 0028-0836. E-ISSN 1476-4687
R&D Projects: GA MŠMT(CZ) LM2023053; GA MŠMT(CZ) LM2018126; GA MŠMT LM2023036; GA MŠMT EF16_013/0001789; GA MŠMT EF18_046/0015861; GA ČR GJ19-19025Y; GA MŠMT(CZ) LM2018129; GA MŠMT(CZ) EF18_046/0016045
Institutional support: RVO:68378050 ; RVO:61388971
Keywords : antibody * enamel * immune response * protein * tolerance * tooth
OECD category: Biochemistry and molecular biology; Immunology (MBU-M)
Impact factor: 64.8, year: 2022
Method of publishing: Limited access
https://www.nature.com/articles/s41586-023-06776-0
Permanent Link: https://hdl.handle.net/11104/0348991 - 3.0573968 - MBÚ 2024 RIV NL eng J - Journal Article
Osičková, Adriana - Knoblochová, Šárka - Bumba, Ladislav - Man, Petr - Kalaninová, Zuzana - Lepesheva, Anna - Jurnečka, David - Čížková, Monika - Biedermannová, Lada - Goldsmith, J. A. - Maynard, J. A. - McLellan, J. S. - Osička, Radim - Šebo, Peter - Mašín, Jiří
A conserved tryptophan in the acylated segment of RTX toxins controls their βinf2/inf integrin–independent cell penetration.
Journal of Biological Chemistry. Roč. 299, č. 8 (2023), č. článku 104978. ISSN 0021-9258. E-ISSN 1083-351X
R&D Projects: GA ČR(CZ) GA22-01558S; GA ČR(CZ) GA22-01558S; GA MŠMT(CZ) LX22NPO5103; GA MŠMT(CZ) EF18_046/0015974; GA ČR(CZ) GX19-27630X
Research Infrastructure: e-INFRA CZ - 90140; EATRIS-CZ IV - 90253; CIISB III - 90242
Institutional support: RVO:61388971 ; RVO:86652036
Keywords : acylated segment * adenylate cyclase toxin * cytotoxicity * hydrogen/deuterium exchange * RTX toxin * thermal stability * tryptophan residue * α-hemolysin * β integrins 2
OECD category: Microbiology
Impact factor: 4.8, year: 2022
Method of publishing: Open access
https://www.sciencedirect.com/science/article/pii/S0021925823020069?via%3Dihub
Permanent Link: https://hdl.handle.net/11104/0344352 - 4.0562903 - MBÚ 2023 RIV CH eng J - Journal Article
Golshani, Maryam - Rahman, Waheed Ur - Osičková, Adriana - Holubová, Jana - Lora, J. - Balashova, N. - Šebo, Peter - Osička, Radim
Filamentous Hemagglutinin of Bordetella pertussis Does Not Interact with the β2 Integrin CD11b/CD18.
International Journal of Molecular Sciences. Roč. 23, č. 20 (2022), č. článku 12598. E-ISSN 1422-0067
R&D Projects: GA MŠMT(CZ) LM2018133; GA MŠMT(CZ) LX22NPO5103
Institutional support: RVO:61388971
Keywords : adenylate cyclase toxin * Bordetella pertussis * CD11b/CD18 * filamentous hemagglutinin * heparin * integrin
OECD category: Microbiology
Impact factor: 5.6, year: 2022
Method of publishing: Open access
https://www.mdpi.com/1422-0067/23/20/12598
Permanent Link: https://hdl.handle.net/11104/0335072File Download Size Commentary Version Access Filamentous Hemagglutinin.pdf 0 4.2 MB Publisher’s postprint open-access - 5.0556379 - MBÚ 2023 RIV CH eng J - Journal Article
Filipi, Kateřina - Rahman, Waheed Ur - Osičková, Adriana - Osička, Radim
Kingella kingae RtxA Cytotoxin in the Context of Other RTX Toxins.
Microorganisms. Roč. 10, č. 3 (2022), č. článku 518. E-ISSN 2076-2607
R&D Projects: GA ČR(CZ) GA22-15825S
Institutional support: RVO:61388971
Keywords : escherichia-coli-hemolysin * adenylate-cyclase toxin * aggregatibacter-actinomycetemcomitans leukotoxin * pasteurella-haemolytica leukotoxin * real-time pcr * polymerase-chain-reaction * outer-membrane vesicles * bordetella-pertussis cyaa * terminal secretion signal * cell-invasive activity * beta(2) integrins * Kingella kingae * membrane * pore-forming * RtxA * RTX toxin
OECD category: Microbiology
Impact factor: 4.5, year: 2022
Method of publishing: Open access
https://www.mdpi.com/2076-2607/10/3/518
Permanent Link: http://hdl.handle.net/11104/0331349 - 6.0549727 - MBÚ 2022 RIV CH eng J - Journal Article
Holubová, Jana - Juhasz, Attila - Mašín, Jiří - Staněk, Ondřej - Jurnečka, David - Osičková, Adriana - Šebo, Peter - Osička, Radim
Selective enhancement of the cell-permeabilizing activity of adenylate cyclase toxin does not increase virulence of bordetella pertussis.
International Journal of Molecular Sciences. Roč. 22, č. 21 (2021), č. článku 11655. E-ISSN 1422-0067
R&D Projects: GA MŠMT(CZ) LM2018133; GA ČR(CZ) GA19-12695S
Research Infrastructure: CIISB II - 90127; CCP II - 90126
Institutional support: RVO:61388971
Keywords : Adenylate cyclase toxin * Bordetella pertussis * CAMP intoxication * Lung colonization * Lung inflammation * Pore-forming activity * RTX toxin * Virulence
OECD category: Microbiology
Impact factor: 6.208, year: 2021
Method of publishing: Open access
https://www.mdpi.com/1422-0067/22/21/11655
Permanent Link: http://hdl.handle.net/11104/0325678 - 7.0547497 - MBÚ 2022 RIV DE eng J - Journal Article
Lepesheva, Anna - Osičková, Adriana - Holubová, Jana - Jurnečka, David - Knoblochová, Šárka - Espinosa-Vinals, Carlos Angel - Bumba, Ladislav - Škopová, Karolína - Fišer, Radovan - Osička, Radim - Šebo, Peter - Mašín, Jiří
Different roles of conserved tyrosine residues of the acylated domains in folding and activity of RTX toxins.
Scientific Reports. Roč. 11, č. 1 (2021), č. článku 19814. ISSN 2045-2322. E-ISSN 2045-2322
R&D Projects: GA MŠMT(CZ) LM2018133; GA ČR(CZ) GA19-12695S; GA ČR(CZ) GX19-27630X; GA ČR(CZ) GA19-04607S
Research Infrastructure: CIISB II - 90127
Institutional support: RVO:61388971
Keywords : adenylate-cyclase toxin * escherichia-coli hemolysin * bordetella-pertussis cyaa * cell-invasive activity * alpha-hemolysin * membrane translocation * complement receptor-3 * fatty-acylation * calcium * binding
OECD category: Biochemistry and molecular biology
Impact factor: 4.997, year: 2021
Method of publishing: Open access
https://www.nature.com/articles/s41598-021-99112-3
Permanent Link: http://hdl.handle.net/11104/0323712 - 8.0547494 - MBÚ 2022 RIV CH eng J - Journal Article
Malandra, Anna - Rahman, Waheed Ur - Klímová, Nela - Streparola, Gaia - Holubová, Jana - Osičková, Adriana - Bariselli, S. - Šebo, Peter - Osička, Radim
Bordetella Adenylate Cyclase Toxin Elicits Airway Mucin Secretion through Activation of the cAMP Response Element Binding Protein.
International Journal of Molecular Sciences. Roč. 22, č. 16 (2021), č. článku 9064. E-ISSN 1422-0067
R&D Projects: GA ČR(CZ) GA19-12695S; GA ČR(CZ) GX19-27630X; GA MŠMT(CZ) LM2018133; GA MŠMT EF18_046/0015861
Research Infrastructure: CCP II - 90126
Institutional support: RVO:61388971
Keywords : adenylate cyclase toxin * Bordetella * cAMP * creb * epithelium * mucin * pertussis toxin
OECD category: Microbiology
Impact factor: 6.208, year: 2021
Method of publishing: Open access
https://www.mdpi.com/1422-0067/22/16/9064
Permanent Link: http://hdl.handle.net/11104/0323707 - 9.0536763 - MBÚ 2021 RIV CH eng J - Journal Article
Rahman, Waheed Ur - Osičková, Adriana - Klímová, Nela - Lora, J. - Balashova, N. - Osička, Radim
Binding of Kingella kingae RtxA Toxin Depends on Cell Surface Oligosaccharides, but Not on beta(2) Integrins.
International Journal of Molecular Sciences. Roč. 21, č. 23 (2020), č. článku 9092. E-ISSN 1422-0067
R&D Projects: GA ČR(CZ) GA18-18079S; GA MŠMT(CZ) LM2018133
Institutional support: RVO:61388971
Keywords : integrins * Kingella kingae * oligosaccharides
OECD category: Microbiology
Impact factor: 5.924, year: 2020
Method of publishing: Open access
https://www.mdpi.com/1422-0067/21/23/9092
Permanent Link: http://hdl.handle.net/11104/0314511 - 10.0533326 - MBÚ 2021 RIV US eng J - Journal Article
Osičková, Adriana - Khaliq, Humaira - Mašín, Jiří - Jurnečka, David - Suková, Anna - Fišer, Radovan - Holubová, Jana - Staněk, Ondřej - Šebo, Peter - Osička, Radim
Acyltransferase-mediated selection of the length of the fatty acyl chain and of the acylation site governs activation of bacterial RTX toxins.
Journal of Biological Chemistry. Roč. 295, č. 28 (2020), s. 9268-9280. ISSN 0021-9258. E-ISSN 1083-351X
R&D Projects: GA MŠMT(CZ) LM2018127
Institutional support: RVO:61388971
Keywords : acylation * acyltransferase * cytotoxicit
OECD category: Microbiology
Impact factor: 5.157, year: 2020
Method of publishing: Open access
Permanent Link: http://hdl.handle.net/11104/0311734