Search results
- 1.0543380 - ÚMG 2022 RIV GB eng J - Journal Article
Mihola, Ondřej - Landa, Vladimír - Pratto, F. - Brick, K. - Kobets, Tetyana - Kusari, Fitore - Gašić, Srdjan - Smagulova, F. - Grey, C. - Flachs, Petr - Gergelits, Václav - Třešňák, Karel - Šilhavý, Jan - Mlejnek, Petr - Camerini-Otero, R.D. - Pravenec, Michal - Petukhova, G.V. - Trachtulec, Zdeněk
Rat PRDM9 shapes recombination landscapes, duration of meiosis, gametogenesis, and age of fertility.
BMC BIOLOGY. Roč. 19, č. 1 (2021), č. článku 86. E-ISSN 1741-7007
R&D Projects: GA ČR(CZ) GA14-20728S; GA ČR(CZ) GA16-06548S; GA ČR GA19-06272S; GA MŠMT(CZ) LQ1604; GA MŠMT(CZ) LM2015040; GA MŠMT(CZ) LM2018126; GA MŠMT(CZ) LM2015062; GA MŠMT(CZ) ED1.1.00/02.0109; GA MŠMT ED2.1.00/19.0395; GA MŠMT(CZ) EF16_013/0001775; GA MŠMT EF18_046/0015861
Research Infrastructure: CERIT-SC - 90085; CESNET II - 90042
Institutional support: RVO:68378050 ; RVO:67985823
Keywords : Rattus norvegicus * Meiotic recombination * prdm9 * Fertility
OECD category: Biology (theoretical, mathematical, thermal, cryobiology, biological rhythm), Evolutionary biology; Genetics and heredity (medical genetics to be 3) (FGU-C)
Impact factor: 7.364, year: 2021
Method of publishing: Open access
https://bmcbiol.biomedcentral.com/articles/10.1186/s12915-021-01017-0
Permanent Link: http://hdl.handle.net/11104/0320594 - 2.0506563 - FGÚ 2020 RIV GB eng J - Journal Article
Olson, E. - Pravenec, Michal - Landa, Vladimír - Koh-Tan, H.H.C. - Dominiczak, A. F. - McBride, M. W. - Graham, D.
Transgenic overexpression of glutathione S-transferase mu-type 1 reduces hypertension and oxidative stress in the stroke-prone spontaneously hypertensive rat.
Journal of Hypertension. Roč. 37, č. 5 (2019), s. 985-996. ISSN 0263-6352. E-ISSN 1473-5598
R&D Projects: GA ČR(CZ) GB14-36804G
Grant - others:AV ČR(CZ) AP1502
Program: Akademická prémie - Praemium Academiae
Institutional support: RVO:67985823
Keywords : glutathione S-transferase mu-type 1 * hypertension * oxidative stress * stroke-prone spontaneously hypertensive rat * transgenic
OECD category: Cardiac and Cardiovascular systems
Impact factor: 4.171, year: 2019
Method of publishing: Open access
https://journals.lww.com/jhypertension/Fulltext/2019/05000/Transgenic_overexpression_of_glutathione.16.aspx
Permanent Link: http://hdl.handle.net/11104/0297797 - 3.0489998 - FGÚ 2019 RIV US eng J - Journal Article
Kuda, Ondřej - Březinová, Marie - Šilhavý, Jan - Landa, Vladimír - Zídek, Václav - Dodia, Ch. - Kreuchwig, F. - Vrbacký, Marek - Balas, L. - Durand, T. - Hübner, N. - Fisher, A. B. - Kopecký, Jan - Pravenec, Michal
Nrf2-Mediated Antioxidant Defense and Peroxiredoxin 6 Are Linked to Biosynthesis of Palmitic Acid Ester of 9-Hydroxystearic Acid.
Diabetes. Roč. 67, č. 6 (2018), s. 1190-1199. ISSN 0012-1797. E-ISSN 1939-327X
R&D Projects: GA ČR(CZ) GA16-04859S; GA ČR(CZ) GJ17-10088Y; GA MŠMT(CZ) ED1.1.00/02.0109; GA MŠMT(CZ) LTAUSA17173
Institutional support: RVO:67985823
Keywords : FAHFAs * white adipose tissue * Nrf2 * lipogenesis * diabetes * PAHSA
OECD category: Endocrinology and metabolism (including diabetes, hormones)
Impact factor: 7.199, year: 2018
Permanent Link: http://hdl.handle.net/11104/0284287 - 4.0489317 - FGÚ 2019 RIV US eng J - Journal Article
Pravenec, Michal - Saba, L. M. - Zídek, Václav - Landa, Vladimír - Mlejnek, Petr - Šilhavý, Jan - Šimáková, Miroslava - Strnad, Hynek - Trnovská, J. - Škop, V. - Hüttl, M. - Marková, I. - Oliyarnyk, O. - Malínská, H. - Kazdová, L. - Smith, H. - Tabakoff, B.
Systems genetic analysis of brown adipose tissue function.
Physiological Genomics. Roč. 50, č. 1 (2018), s. 52-66. ISSN 1094-8341. E-ISSN 1531-2267
R&D Projects: GA ČR(CZ) GA13-04420S
Institutional support: RVO:67985823 ; RVO:68378050
Keywords : brown adipose tissue * coexpression modules * quantitative trait locus * recombinant inbred strains * spontaneously hypertensive rat
OECD category: Human genetics
Impact factor: 2.581, year: 2018
Permanent Link: http://hdl.handle.net/11104/0283756 - 5.0484413 - FGÚ 2018 RIV CZ eng J - Journal Article
Pravenec, Michal - Zídek, Václav - Landa, Vladimír - Mlejnek, Petr - Šilhavý, Jan - Šimáková, Miroslava - Trnovská, J. - Škop, V. - Marková, I. - Malínská, H. - Hüttl, M. - Kazdová, L. - Bardová, Kristina - Tauchmannová, Kateřina - Vrbacký, Marek - Nůsková, Hana - Mráček, Tomáš - Kopecký, Jan - Houštěk, Josef
Mutant Wars2 gene in spontaneously hypertensive rats impairs brown adipose tissue function and predisposes to visceral obesity.
Physiological Research. Roč. 66, č. 6 (2017), s. 917-924. ISSN 0862-8408. E-ISSN 1802-9973
R&D Projects: GA ČR(CZ) GA13-04420S
Institutional support: RVO:67985823
Keywords : brown adipose tissue * spontaneously hypertensive rat * quantitative trait loci * transgenic * Wars2 gene * mitochondrial proteosynthesis
OECD category: Endocrinology and metabolism (including diabetes, hormones)
Impact factor: 1.324, year: 2017
Permanent Link: http://hdl.handle.net/11104/0279584 - 6.0477017 - FGÚ 2018 RIV US eng J - Journal Article
Trnovská, J. - Šilhavý, Jan - Kuda, Ondřej - Landa, Vladimír - Zídek, Václav - Mlejnek, Petr - Šimáková, Miroslava - Strnad, Hynek - Škop, V. - Oliyarnyk, O. - Kazdová, L. - Haluzík, M. - Pravenec, Michal
Salsalate ameliorates metabolic disturbances by reducing inflammation in spontaneously hypertensive rats expressing human C-reactive protein and by activating brown adipose tissue in nontransgenic controls.
PLoS ONE. Roč. 12, č. 6 (2017), č. článku e0179063. ISSN 1932-6203. E-ISSN 1932-6203
R&D Projects: GA ČR(CZ) GA13-04420S
Institutional support: RVO:67985823 ; RVO:68378050
Keywords : inflammation * insulin resistance * C-reactive protein * spintaneously hypertensive rat * salsalate
OECD category: Endocrinology and metabolism (including diabetes, hormones); Endocrinology and metabolism (including diabetes, hormones) (UMG-J)
Impact factor: 2.766, year: 2017
Permanent Link: http://hdl.handle.net/11104/0273422 - 7.0474947 - FGÚ 2018 RIV US eng J - Journal Article
Liška, F. - Landa, Vladimír - Zídek, Václav - Mlejnek, Petr - Šilhavý, Jan - Šimáková, Miroslava - Strnad, Hynek - Trnovská, J. - Škop, V. - Kazdová, L. - Starker, C.G. - Voytas, D.F. - Izsvák, Z. - Mancini, M. - Šeda, O. - Křen, V. - Pravenec, Michal
Downregulation of Plzf Gene Ameliorates Metabolic and Cardiac Traits in the Spontaneously Hypertensive Rat.
Hypertension. Roč. 69, č. 6 (2017), s. 1084-1091. ISSN 0194-911X. E-ISSN 1524-4563
R&D Projects: GA ČR(CZ) GB14-36804G; GA MŠMT(CZ) LL1204
Institutional support: RVO:67985823 ; RVO:68378050
Keywords : fibrosis * hypertension * hypertrophy * left ventricular rats * inbred * SHR * transcriptome
OECD category: Cardiac and Cardiovascular systems; Cardiac and Cardiovascular systems (UMG-J)
Impact factor: 6.823, year: 2017
Permanent Link: http://hdl.handle.net/11104/0271844 - 8.0470546 - ÚEM 2017 RIV US eng J - Journal Article
Liška, F. - Peterková, Renata - Peterka, Miroslav - Landa, Vladimír - Zídek, Václav - Mlejnek, Petr - Šilhavý, Jan - Šimáková, Miroslava - Křen, Vladimír - Starker, C.G. - Voytas, D.F. - Izsvák, Z. - Pravenec, Michal
Targeting of the Plzf Gene in the Rat by Transcription Activator-Like Effector Nuclease Results in Caudal Regression Syndrome in Spontaneously Hypertensive Rats.
PLoS ONE. Roč. 11, č. 10 (2016), e0164206. ISSN 1932-6203. E-ISSN 1932-6203
R&D Projects: GA ČR(CZ) GB14-37368G
Institutional support: RVO:68378041 ; RVO:67985823
Keywords : cell self-renewal * blood-pressure * limb * chromosome-8
Subject RIV: EA - Cell Biology; EB - Genetics ; Molecular Biology (FGU-C)
Impact factor: 2.806, year: 2016
Permanent Link: http://hdl.handle.net/11104/0268150 - 9.0467648 - FGÚ 2017 RIV CZ eng J - Journal Article
Pravenec, Michal - Landa, Vladimír - Zídek, Václav - Mlejnek, Petr - Šilhavý, Jan - Mir, S.A. - Vaingankar, S. M. - Wang, J. - Kurtz, T. W.
Effects of transgenic expression of dopamine beta hydroxylase (Dbh) gene on blood pressure in spontaneously hypertensive rats.
Physiological Research. Roč. 65, č. 6 (2016), s. 1039-1044. ISSN 0862-8408. E-ISSN 1802-9973
R&D Projects: GA ČR(CZ) GAP301/12/0696; GA TA ČR(CZ) TA02010013
Institutional support: RVO:67985823
Keywords : spontaneously hypertensive rat * transgenic * dopamine beta hydroxylase * catecholamines * blood pressure * left ventricular mass
Subject RIV: FB - Endocrinology, Diabetology, Metabolism, Nutrition
Impact factor: 1.461, year: 2016
Permanent Link: http://hdl.handle.net/11104/0265717 - 10.0467424 - FGÚ 2017 RIV CZ eng J - Journal Article
Škop, V. - Trnovská, J. - Oliyarnyk, O. - Marková, I. - Malínská, H. - Kazdová, L. - Zídek, Václav - Landa, Vladimír - Mlejnek, Petr - Šimáková, Miroslava - Kůdela, M. - Pravenec, Michal - Šilhavý, Jan
Hepatotoxic effects of fenofibrate in spontaneously hypertensive rats expressing human C-reactive protein.
Physiological Research. Roč. 65, č. 6 (2016), s. 891-899. ISSN 0862-8408. E-ISSN 1802-9973
R&D Projects: GA MZd(CZ) NT14325
Institutional support: RVO:67985823
Keywords : fenofibrate * rosuvastatin * C-reactive protein * transgenic * spontaneously hypertensive rat * inflammation * hepatotoxic
Subject RIV: FB - Endocrinology, Diabetology, Metabolism, Nutrition
Impact factor: 1.461, year: 2016
Permanent Link: http://hdl.handle.net/11104/0265527