Search results

  1. 1.
    0582771 - FGÚ 2025 RIV US eng J - Journal Article
    Chiang, A. C. Y. - Ježek, J. - Mu, P. - Di, Y. - Klucnika, A. - Jabůrek, Martin - Ježek, Petr - Ma, H.
    Two mitochondrial DNA polymorphisms modulate cardiolipin binding and lead to synthetic lethality.
    Nature Communications. Roč. 15, č. 1 (2024), č. článku 611. E-ISSN 2041-1723
    R&D Projects: GA ČR(CZ) GA22-17173S; GA ČR(CZ) GA21-01205S
    Institutional support: RVO:67985823
    Keywords : mitochondria * eukaryote * genetic interaction
    OECD category: Biochemistry and molecular biology
    Impact factor: 16.6, year: 2022
    Method of publishing: Open access
    https://doi.org/10.1038/s41467-024-44964-2
    Permanent Link: https://hdl.handle.net/11104/0351176
     
     
  2. 2.
    0577681 - FGÚ 2024 RIV US eng J - Journal Article
    Ježek, Petr - Jabůrek, Martin - Holendová, Blanka - Engstová, Hana - Dlasková, Andrea
    Mitochondrial Cristae Morphology Reflecting Metabolism, Superoxide Formation, Redox Homeostasis, and Pathology.
    Antioxidants & Redox Signaling. Roč. 39, 10-12 (2023), s. 635-683. ISSN 1523-0864. E-ISSN 1557-7716
    R&D Projects: GA ČR(CZ) GA21-01205S; GA ČR(CZ) GA23-05798S; GA ČR(CZ) GA22-02203S; GA MŠMT(CZ) EF18_046/0016045
    Institutional support: RVO:67985823
    Keywords : mitochondrial cristae * mitochondrial superoxide formation * ATP-synthase dimeric rows * MICOS * OPA1 * respiratory chain supercomplexes
    OECD category: Physiology (including cytology)
    Impact factor: 6.6, year: 2022
    Method of publishing: Open access
    https://doi.org/10.1089/ars.2022.0173
    Permanent Link: https://hdl.handle.net/11104/0346809
     
     
  3. 3.
    0557977 - FGÚ 2023 RIV US eng J - Journal Article
    Ježek, Petr - Holendová, Blanka - Jabůrek, Martin - Dlasková, Andrea - Plecitá-Hlavatá, Lydie
    Contribution of Mitochondria to Insulin Secretion by Various Secretagogues.
    Antioxidants & Redox Signaling. Roč. 36, č. 13 (2022), s. 920-952. ISSN 1523-0864. E-ISSN 1557-7716
    R&D Projects: GA ČR(CZ) GA20-00408S
    Institutional support: RVO:67985823
    Keywords : pancreatic beta-cell metabolism * insulin secretion * redox signaling * mitochondrial Ca2+ transport * branched-chain ketoacid oxidation * fatty acid-stimulated insulin secretion * ATP-sensitive K+ channel * TRPM channels * GLP-1
    OECD category: Endocrinology and metabolism (including diabetes, hormones)
    Impact factor: 6.6, year: 2022
    Method of publishing: Open access
    https://doi.org/10.1089/ars.2021.0113
    Permanent Link: http://hdl.handle.net/11104/0331854
     
     
  4. 4.
    0556528 - FGÚ 2023 RIV CH eng J - Journal Article
    Průchová, Pavla - Gotvaldová, Klára - Smolková, Katarína - Alán, Lukáš - Holendová, Blanka - Tauber, Jan - Galkin, A. - Ježek, Petr - Jabůrek, Martin
    Antioxidant Role and Cardiolipin Remodeling by Redox-Activated Mitochondrial Ca2+-Independent Phospholipase A(2)gamma in the Brain.
    Antioxidants. Roč. 11, č. 2 (2022), č. článku 198. E-ISSN 2076-3921
    R&D Projects: GA MŠMT(CZ) LTAUSA17174; GA ČR(CZ) GA22-17173S
    Institutional support: RVO:67985823
    Keywords : mitochondria * phospholipase iPLA(2)gamma/PNPLA8 * adenine nucleotide translocase * redox homeostasis * cardiolipin remodeling
    OECD category: Biochemistry and molecular biology
    Impact factor: 7, year: 2022
    Method of publishing: Open access
    https://www.mdpi.com/2076-3921/11/2/198
    Permanent Link: http://hdl.handle.net/11104/0331137
     
     
  5. 5.
    0542843 - FGÚ 2022 RIV CH eng J - Journal Article
    Jabůrek, Martin - Průchová, Pavla - Holendová, Blanka - Galkin, A. - Ježek, Petr
    Antioxidant Synergy of Mitochondrial Phospholipase PNPLA8/iPLA2 gamma with Fatty Acid-Conducting SLC25 Gene Family Transporters.
    Antioxidants. Roč. 10, č. 5 (2021), č. článku 678. E-ISSN 2076-3921
    R&D Projects: GA MŠMT(CZ) LTAUSA17174
    Institutional support: RVO:67985823
    Keywords : antioxidant synergy * mitochondrial phospholipase A2γ * mitochondrial uncoupling proteins * adenine nucleotide translocase * mitochondrial carriers * SLC25 gene family * lipid peroxidation * cytoprotection
    OECD category: Biochemistry and molecular biology
    Impact factor: 7.675, year: 2021
    Method of publishing: Open access
    https://www.mdpi.com/2076-3921/10/5/678
    Permanent Link: http://hdl.handle.net/11104/0320184
     
     
  6. 6.
    0541624 - FGÚ 2022 RIV CH eng J - Journal Article
    Ježek, Petr - Holendová, Blanka - Jabůrek, Martin - Tauber, Jan - Dlasková, Andrea - Plecitá-Hlavatá, Lydie
    The Pancreatic beta-Cell: The Perfect Redox System.
    Antioxidants. Roč. 10, č. 2 (2021), č. článku 197. E-ISSN 2076-3921
    R&D Projects: GA ČR(CZ) GA20-00408S
    Institutional support: RVO:67985823
    Keywords : pancreatic beta-cells * insulin secretion * redox signaling * NADPH oxidase 4 * branched-chain ketoacid oxidation * fatty-acid-stimulated insulin secretion * TRPM channels * ATP-sensitive K+ channel * GLP-1 * GPR40
    OECD category: Endocrinology and metabolism (including diabetes, hormones)
    Impact factor: 7.675, year: 2021
    Method of publishing: Open access
    https://www.mdpi.com/2076-3921/10/2/197
    Permanent Link: http://hdl.handle.net/11104/0319157
     
     
  7. 7.
    0531109 - FGÚ 2021 RIV US eng J - Journal Article
    Plecitá-Hlavatá, Lydie - Jabůrek, Martin - Holendová, Blanka - Tauber, Jan - Pavluch, Vojtěch - Berková, Z. - Cahová, M. - Schröder, K. - Brandes, R. P. - Siemen, D. - Ježek, Petr
    Glucose-Stimulated Insulin Secretion Fundamentally Requires H(2)O(2)Signaling by NADPH Oxidase 4.
    Diabetes. Roč. 69, č. 7 (2020), s. 1341-1354. ISSN 0012-1797. E-ISSN 1939-327X
    R&D Projects: GA ČR(CZ) GA20-00408S; GA ČR(CZ) GA16-06700S; GA ČR(CZ) GA17-01813S
    Institutional support: RVO:67985823
    Keywords : glucose-stimulated insulin secretion * NADPH oxidase NOX4 * ATP-sensitive potassium channel * cytosolic H2O2 redox signaling * beta-cell-specific NOX4 knockout mice * 2-oxo-isocaproate
    OECD category: Endocrinology and metabolism (including diabetes, hormones)
    Impact factor: 9.461, year: 2020
    Method of publishing: Open access
    https://doi.org/10.2337/db19-1130
    Permanent Link: http://hdl.handle.net/11104/0309847
     
     
  8. 8.
    0510404 - FGÚ 2020 RIV US eng J - Journal Article
    Ježek, Petr - Jabůrek, Martin - Plecitá-Hlavatá, Lydie
    Contribution of Oxidative Stress and Impaired Biogenesis of Pancreatic beta-Cells to Type 2 Diabetes.
    Antioxidants & Redox Signaling. Roč. 31, č. 10 (2019), s. 722-751. ISSN 1523-0864. E-ISSN 1557-7716
    R&D Projects: GA ČR(CZ) GA16-06700S; GA ČR(CZ) GA17-01813S
    Institutional support: RVO:67985823
    Keywords : pancreatic beta-cells * type 2 diabetes * oxidative stress * impaired redox signaling * beta-cell identity self-checking * dedifferentiation
    OECD category: Endocrinology and metabolism (including diabetes, hormones)
    Impact factor: 7.040, year: 2019
    Method of publishing: Open access
    https://doi.org/10.1089/ars.2018.7656
    Permanent Link: http://hdl.handle.net/11104/0300914
     
     
  9. 9.
    0504243 - FGÚ 2020 RIV NL eng J - Journal Article
    Ježek, Petr - Jabůrek, Martin - Porter, R. K.
    Uncoupling mechanism and redox regulation of mitochondrial uncoupling protein 1 (UCP1).
    Biochimica Et Biophysica Acta-Bioenergetics. Roč. 1860, č. 3 (2019), s. 259-269. ISSN 0005-2728. E-ISSN 1879-2650
    R&D Projects: GA ČR(CZ) GA17-01813S; GA MŠMT(CZ) LTAUSA17174
    Institutional support: RVO:67985823
    Keywords : mitochondrial uncoupling protein1 * UCP1 * fatty acid cycling * brown adipose tissue * redox regulation
    OECD category: Physiology (including cytology)
    Impact factor: 3.465, year: 2019
    Method of publishing: Open access
    https://doi.org/10.1016/j.bbabio.2018.11.007
    Permanent Link: http://hdl.handle.net/11104/0295921
     
     
  10. 10.
    0493406 - FGÚ 2019 RIV CH eng J - Journal Article
    Ježek, Petr - Jabůrek, Martin - Holendová, Blanka - Plecitá-Hlavatá, Lydie
    Fatty Acid-Stimulated Insulin Secretion vs. Lipotoxicity.
    Molecules. Roč. 23, č. 6 (2018), č. článku 1483. E-ISSN 1420-3049
    R&D Projects: GA ČR(CZ) GA16-06700S
    Institutional support: RVO:67985823
    Keywords : fatty acids * fatty acid-stimulated insulin secretion * GPR40 * pancreatic beta-cells * oxidative stress * lipotoxicity * type 2 diabetes * low-grade inflammation
    OECD category: Endocrinology and metabolism (including diabetes, hormones)
    Impact factor: 3.060, year: 2018
    Permanent Link: http://hdl.handle.net/11104/0286770
     
     

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