Search results
- 1.0582771 - FGÚ 2025 RIV US eng J - Journal Article
Chiang, A. C. Y. - Ježek, J. - Mu, P. - Di, Y. - Klucnika, A. - Jabůrek, Martin - Ježek, Petr - Ma, H.
Two mitochondrial DNA polymorphisms modulate cardiolipin binding and lead to synthetic lethality.
Nature Communications. Roč. 15, č. 1 (2024), č. článku 611. E-ISSN 2041-1723
R&D Projects: GA ČR(CZ) GA22-17173S; GA ČR(CZ) GA21-01205S
Institutional support: RVO:67985823
Keywords : mitochondria * eukaryote * genetic interaction
OECD category: Biochemistry and molecular biology
Impact factor: 16.6, year: 2022
Method of publishing: Open access
https://doi.org/10.1038/s41467-024-44964-2
Permanent Link: https://hdl.handle.net/11104/0351176 - 2.0577681 - FGÚ 2024 RIV US eng J - Journal Article
Ježek, Petr - Jabůrek, Martin - Holendová, Blanka - Engstová, Hana - Dlasková, Andrea
Mitochondrial Cristae Morphology Reflecting Metabolism, Superoxide Formation, Redox Homeostasis, and Pathology.
Antioxidants & Redox Signaling. Roč. 39, 10-12 (2023), s. 635-683. ISSN 1523-0864. E-ISSN 1557-7716
R&D Projects: GA ČR(CZ) GA21-01205S; GA ČR(CZ) GA23-05798S; GA ČR(CZ) GA22-02203S; GA MŠMT(CZ) EF18_046/0016045
Institutional support: RVO:67985823
Keywords : mitochondrial cristae * mitochondrial superoxide formation * ATP-synthase dimeric rows * MICOS * OPA1 * respiratory chain supercomplexes
OECD category: Physiology (including cytology)
Impact factor: 6.6, year: 2022
Method of publishing: Open access
https://doi.org/10.1089/ars.2022.0173
Permanent Link: https://hdl.handle.net/11104/0346809 - 3.0557977 - FGÚ 2023 RIV US eng J - Journal Article
Ježek, Petr - Holendová, Blanka - Jabůrek, Martin - Dlasková, Andrea - Plecitá-Hlavatá, Lydie
Contribution of Mitochondria to Insulin Secretion by Various Secretagogues.
Antioxidants & Redox Signaling. Roč. 36, č. 13 (2022), s. 920-952. ISSN 1523-0864. E-ISSN 1557-7716
R&D Projects: GA ČR(CZ) GA20-00408S
Institutional support: RVO:67985823
Keywords : pancreatic beta-cell metabolism * insulin secretion * redox signaling * mitochondrial Ca2+ transport * branched-chain ketoacid oxidation * fatty acid-stimulated insulin secretion * ATP-sensitive K+ channel * TRPM channels * GLP-1
OECD category: Endocrinology and metabolism (including diabetes, hormones)
Impact factor: 6.6, year: 2022
Method of publishing: Open access
https://doi.org/10.1089/ars.2021.0113
Permanent Link: http://hdl.handle.net/11104/0331854 - 4.0556528 - FGÚ 2023 RIV CH eng J - Journal Article
Průchová, Pavla - Gotvaldová, Klára - Smolková, Katarína - Alán, Lukáš - Holendová, Blanka - Tauber, Jan - Galkin, A. - Ježek, Petr - Jabůrek, Martin
Antioxidant Role and Cardiolipin Remodeling by Redox-Activated Mitochondrial Ca2+-Independent Phospholipase A(2)gamma in the Brain.
Antioxidants. Roč. 11, č. 2 (2022), č. článku 198. E-ISSN 2076-3921
R&D Projects: GA MŠMT(CZ) LTAUSA17174; GA ČR(CZ) GA22-17173S
Institutional support: RVO:67985823
Keywords : mitochondria * phospholipase iPLA(2)gamma/PNPLA8 * adenine nucleotide translocase * redox homeostasis * cardiolipin remodeling
OECD category: Biochemistry and molecular biology
Impact factor: 7, year: 2022
Method of publishing: Open access
https://www.mdpi.com/2076-3921/11/2/198
Permanent Link: http://hdl.handle.net/11104/0331137 - 5.0542843 - FGÚ 2022 RIV CH eng J - Journal Article
Jabůrek, Martin - Průchová, Pavla - Holendová, Blanka - Galkin, A. - Ježek, Petr
Antioxidant Synergy of Mitochondrial Phospholipase PNPLA8/iPLA2 gamma with Fatty Acid-Conducting SLC25 Gene Family Transporters.
Antioxidants. Roč. 10, č. 5 (2021), č. článku 678. E-ISSN 2076-3921
R&D Projects: GA MŠMT(CZ) LTAUSA17174
Institutional support: RVO:67985823
Keywords : antioxidant synergy * mitochondrial phospholipase A2γ * mitochondrial uncoupling proteins * adenine nucleotide translocase * mitochondrial carriers * SLC25 gene family * lipid peroxidation * cytoprotection
OECD category: Biochemistry and molecular biology
Impact factor: 7.675, year: 2021
Method of publishing: Open access
https://www.mdpi.com/2076-3921/10/5/678
Permanent Link: http://hdl.handle.net/11104/0320184 - 6.0541624 - FGÚ 2022 RIV CH eng J - Journal Article
Ježek, Petr - Holendová, Blanka - Jabůrek, Martin - Tauber, Jan - Dlasková, Andrea - Plecitá-Hlavatá, Lydie
The Pancreatic beta-Cell: The Perfect Redox System.
Antioxidants. Roč. 10, č. 2 (2021), č. článku 197. E-ISSN 2076-3921
R&D Projects: GA ČR(CZ) GA20-00408S
Institutional support: RVO:67985823
Keywords : pancreatic beta-cells * insulin secretion * redox signaling * NADPH oxidase 4 * branched-chain ketoacid oxidation * fatty-acid-stimulated insulin secretion * TRPM channels * ATP-sensitive K+ channel * GLP-1 * GPR40
OECD category: Endocrinology and metabolism (including diabetes, hormones)
Impact factor: 7.675, year: 2021
Method of publishing: Open access
https://www.mdpi.com/2076-3921/10/2/197
Permanent Link: http://hdl.handle.net/11104/0319157 - 7.0531109 - FGÚ 2021 RIV US eng J - Journal Article
Plecitá-Hlavatá, Lydie - Jabůrek, Martin - Holendová, Blanka - Tauber, Jan - Pavluch, Vojtěch - Berková, Z. - Cahová, M. - Schröder, K. - Brandes, R. P. - Siemen, D. - Ježek, Petr
Glucose-Stimulated Insulin Secretion Fundamentally Requires H(2)O(2)Signaling by NADPH Oxidase 4.
Diabetes. Roč. 69, č. 7 (2020), s. 1341-1354. ISSN 0012-1797. E-ISSN 1939-327X
R&D Projects: GA ČR(CZ) GA20-00408S; GA ČR(CZ) GA16-06700S; GA ČR(CZ) GA17-01813S
Institutional support: RVO:67985823
Keywords : glucose-stimulated insulin secretion * NADPH oxidase NOX4 * ATP-sensitive potassium channel * cytosolic H2O2 redox signaling * beta-cell-specific NOX4 knockout mice * 2-oxo-isocaproate
OECD category: Endocrinology and metabolism (including diabetes, hormones)
Impact factor: 9.461, year: 2020
Method of publishing: Open access
https://doi.org/10.2337/db19-1130
Permanent Link: http://hdl.handle.net/11104/0309847 - 8.0510404 - FGÚ 2020 RIV US eng J - Journal Article
Ježek, Petr - Jabůrek, Martin - Plecitá-Hlavatá, Lydie
Contribution of Oxidative Stress and Impaired Biogenesis of Pancreatic beta-Cells to Type 2 Diabetes.
Antioxidants & Redox Signaling. Roč. 31, č. 10 (2019), s. 722-751. ISSN 1523-0864. E-ISSN 1557-7716
R&D Projects: GA ČR(CZ) GA16-06700S; GA ČR(CZ) GA17-01813S
Institutional support: RVO:67985823
Keywords : pancreatic beta-cells * type 2 diabetes * oxidative stress * impaired redox signaling * beta-cell identity self-checking * dedifferentiation
OECD category: Endocrinology and metabolism (including diabetes, hormones)
Impact factor: 7.040, year: 2019
Method of publishing: Open access
https://doi.org/10.1089/ars.2018.7656
Permanent Link: http://hdl.handle.net/11104/0300914 - 9.0504243 - FGÚ 2020 RIV NL eng J - Journal Article
Ježek, Petr - Jabůrek, Martin - Porter, R. K.
Uncoupling mechanism and redox regulation of mitochondrial uncoupling protein 1 (UCP1).
Biochimica Et Biophysica Acta-Bioenergetics. Roč. 1860, č. 3 (2019), s. 259-269. ISSN 0005-2728. E-ISSN 1879-2650
R&D Projects: GA ČR(CZ) GA17-01813S; GA MŠMT(CZ) LTAUSA17174
Institutional support: RVO:67985823
Keywords : mitochondrial uncoupling protein1 * UCP1 * fatty acid cycling * brown adipose tissue * redox regulation
OECD category: Physiology (including cytology)
Impact factor: 3.465, year: 2019
Method of publishing: Open access
https://doi.org/10.1016/j.bbabio.2018.11.007
Permanent Link: http://hdl.handle.net/11104/0295921 - 10.0493406 - FGÚ 2019 RIV CH eng J - Journal Article
Ježek, Petr - Jabůrek, Martin - Holendová, Blanka - Plecitá-Hlavatá, Lydie
Fatty Acid-Stimulated Insulin Secretion vs. Lipotoxicity.
Molecules. Roč. 23, č. 6 (2018), č. článku 1483. E-ISSN 1420-3049
R&D Projects: GA ČR(CZ) GA16-06700S
Institutional support: RVO:67985823
Keywords : fatty acids * fatty acid-stimulated insulin secretion * GPR40 * pancreatic beta-cells * oxidative stress * lipotoxicity * type 2 diabetes * low-grade inflammation
OECD category: Endocrinology and metabolism (including diabetes, hormones)
Impact factor: 3.060, year: 2018
Permanent Link: http://hdl.handle.net/11104/0286770