Search results
- 1.0583492 - BFÚ 2024 RIV NL eng J - Journal Article
Sladekova, L. - Zgarbova, E. - Vrzal, R. - Vanda, D. - Soural, M. - Jakubcová, Klára - Vazquez-Gomez, Gerardo - Vondráček, Jan - Dvořák, Z.
Switching on/off aryl hydrocarbon receptor and pregnane X receptor activities by chemically modified tryptamines.
Toxicology Letters. Roč. 387, SEP 15 2023 (2023), s. 63-75. ISSN 0378-4274. E-ISSN 1879-3169
R&D Projects: GA ČR(CZ) GA22-00355S
Institutional support: RVO:68081707
Keywords : nuclear receptors * pxr * ahr * activation * antagonists * metabolism * tryptophan * ligands * target
OECD category: Toxicology
Impact factor: 3.5, year: 2022
Method of publishing: Limited access
https://www.sciencedirect.com/science/article/pii/S037842742301055X?via%3Dihub
Permanent Link: https://hdl.handle.net/11104/0351455 - 2.0576971 - BFÚ 2024 RIV GB eng J - Journal Article
Holmej, J. A. - Vondráček, Jan - Machala, M. - Lagadic-Gossmann, D. - Vogel, C. - Le Ferrec, E. - Sparfel, L. - Ovrevik, J.
Lung cancer associated with combustion particles and fine particulate matter (PM2.5) The roles of polycyclic aromatic hydrocarbons (PAHs) and the aryl hydrocarbon receptor (AhR).
Biochemical Pharmacology. Roč. 216, OCT 2023 (2023), č. článku 115801. ISSN 0006-2952. E-ISSN 1873-2968
R&D Projects: GA ČR(CZ) GA21-00533S
Institutional support: RVO:68081707
Keywords : Air pollution * Diesel exhaust * Smoking * Occupational exposure * Carcinogenesis * Genotoxicity * Inflammation * Tumor promotion * Tumor microenvironment
OECD category: Pharmacology and pharmacy
Impact factor: 5.8, year: 2022
Method of publishing: Open access
https://www.sciencedirect.com/science/article/pii/S0006295223003921?via%3Dihub
Permanent Link: https://hdl.handle.net/11104/0350475 - 3.0576968 - BFÚ 2024 RIV GB eng J - Journal Article
Vazquez-Gomez, Gerardo - Petráš, Jiří - Dvořák, Z. - Vondráček, Jan
Aryl hydrocarbon receptor (AhR) and pregnane X receptor (PXR) play both distinct and common roles in the regulation of colon homeostasis and intestinal carcinogenesis.
Biochemical Pharmacology. Roč. 216, OCT 2023 (2023), č. článku 115797. ISSN 0006-2952. E-ISSN 1873-2968
R&D Projects: GA ČR(CZ) GA22-00355S
Institutional support: RVO:68081707
Keywords : Colon cancer * Aryl hydrocarbon receptor * Pregnane X receptor * Intestine * Microbial agonists * Inflammation * Epithelial barrier * Dietary contaminants
OECD category: Pharmacology and pharmacy
Impact factor: 5.8, year: 2022
Method of publishing: Limited access
https://www.sciencedirect.com/science/article/pii/S000629522300388X?via%3Dihub
Permanent Link: https://hdl.handle.net/11104/0350474 - 4.0571976 - BFÚ 2024 RIV NL eng J - Journal Article
Marvanová, S. - Pěnčíková, K. - Palková, L. - Ciganek, M. - Petráš, Jiří - Lněničková, Anna - Vondráček, Jan - Machala, M.
Benzo[b]naphtho[d]thiophenes and naphthylbenzo[b]thiophenes: Their aryl hydrocarbon receptor-mediated activities and environmental presence.
Science of the Total Environment. Roč. 879, JUN 25 2023 (2023), č. článku 162924. ISSN 0048-9697. E-ISSN 1879-1026
R&D Projects: GA ČR(CZ) GA21-00533S
Institutional support: RVO:68081707
Keywords : Polycyclic aromatic sulfur heterocyclic * compounds * AhR activity * Gap junctional intercellular communication * Airborne particulate matter * Freshwater sediments
OECD category: Ecology
Impact factor: 9.8, year: 2022
Method of publishing: Limited access
https://www.sciencedirect.com/science/article/pii/S0048969723015401?via%3Dihub
Permanent Link: https://hdl.handle.net/11104/0349923 - 5.0569428 - BFÚ 2023 RIV NL eng J - Journal Article
Bernal, K. - Touma, C. - Erradhouani, C. - Boronat-Belda, T. - Gaillard, L. - Al Kassir, S. - Le Mentec, H. - Martin-Chouly, C. - Podechard, N. - Lagadic-Gossmann, D. - Langouet, S. - Brion, F. - Knoll-Gellida, A. - Babin, P. J. - Sovadinová, I. - Babica, P. - Andreau, K. - Barouki, R. - Vondráček, Jan - Alonso-Magdalena, P. - Blanc, E. - Kim, M. - J. - Coumoul, X.
Combinatorial pathway disruption is a powerful approach to delineate metabolic impacts of endocrine disruptors.
FEBS Letters. Roč. 596, č. 24 (2022), s. 3107-3123. ISSN 0014-5793. E-ISSN 1873-3468
Institutional support: RVO:68081707
Keywords : appetite * bisphenol * dioxin * inflammation * insulin resistance * microbiota * perfluorinated compounds
OECD category: Biochemistry and molecular biology
Impact factor: 3.5, year: 2022
Method of publishing: Open access
https://febs.onlinelibrary.wiley.com/doi/10.1002/1873-3468.14465
Permanent Link: https://hdl.handle.net/11104/0340757 - 6.0561061 - BFÚ 2023 RIV CH eng J - Journal Article
Karasová, Martina - Procházková, Jiřina - Tylichová, Zuzana - Fedr, Radek - Ciganek, M. - Machala, M. - Dvořák, Z. - Vyhlidalova, B. - Zuvalova, I. - Ehrmann, J. - Bouchal, J. - Andrysík, Z. - Vondráček, Jan
Inhibition of Aryl Hydrocarbon Receptor (AhR) Expression Disrupts Cell Proliferation and Alters Energy Metabolism and Fatty Acid Synthesis in Colon Cancer Cells.
Cancers (Basel). Roč. 14, č. 17 (2022), č. článku 4245. E-ISSN 2072-6694
R&D Projects: GA ČR(CZ) GA19-00236S; GA MZd(CZ) NU21-03-00421
Institutional support: RVO:68081707
Keywords : colon cancer cells * AhR * metabolism * proliferation * fatty acid synthesis * Akt pathway
OECD category: Oncology
Impact factor: 5.2, year: 2022
Method of publishing: Open access
https://www.mdpi.com/2072-6694/14/17/4245
Permanent Link: https://hdl.handle.net/11104/0340614 - 7.0560190 - ÚŽFG 2023 RIV GB eng J - Journal Article
Smutná, Tereza - Dumková, J. - Kristeková, Daniela - Laštovičková, Markéta - Jedličková, Adriena - Vrlíková, Lucie - Dočekal, Bohumil - Alexa, Lukáš - Kotasová, H. - Pelková, V. - Večeřa, Zbyněk - Křůmal, Kamil - Petráš, Jiří - Coufalík, Pavel - Všianský, D. - Záchej, S. - Pinkas, Dominik - Vondráček, Jan - Hampl, A. - Mikuška, Pavel - Buchtová, Marcela
Macrophage-mediated tissue response evoked by subchronic inhalation of lead oxide nanoparticles is associated with the alteration of phospholipases C and cholesterol transporters.
Particle and Fibre Toxicology. Roč. 19, č. 1 (2022), č. článku 52. ISSN 1743-8977. E-ISSN 1743-8977
R&D Projects: GA ČR(CZ) GA20-02203S
Institutional support: RVO:67985904 ; RVO:68081715 ; RVO:68081707 ; RVO:68378050
Keywords : lead oxide nanoparticles * inhalation * lung macrophages * liver macrophages * cholesterol metabolism
OECD category: Toxicology; Analytical chemistry (UIACH-O); Analytical chemistry (BFU-R)
Impact factor: 10, year: 2022
Method of publishing: Open access
https://particleandfibretoxicology.biomedcentral.com/articles/10.1186/s12989-022-00494-7
Permanent Link: https://hdl.handle.net/11104/0333197 - 8.0558379 - BFÚ 2023 RIV US eng J - Journal Article
Heindel, J. J. - Howard, S. - Agay-Shay, K. - Arrebola, J. - Audouze, K. - Babin, P. - Barouki, R. - Bansal, A. - Blanc, E. - Cave, M. - Chatterjee, S. - Chevalier, N. - Choudhury, M. - Collier, D. - Connolly, L. - Coumoul, X. - Garruti, G. - Gilbertson, M. - Hoepner, L. - Holloway, A. K. - Howell Iii, G. - Kassotis, C. - Kay, M. - Kim, M. - Lagadic-Gossmann, D. - Langouet, S. - Legrand, A. - Li, Z. - Le Mentec, H. - Lind, A. L. - Vondráček, Jan … Total 43 authors
Obesity II: Establishing causal links between chemical exposures and obesity.
Biochemical Pharmacology. Roč. 199, MAY 2022 (2022), č. článku 115015. ISSN 0006-2952. E-ISSN 1873-2968
R&D Projects: GA ČR(CZ) GA21-00533S
Institutional support: RVO:68081707
Keywords : endocrine-disrupting chemicals * persistent organic pollutants * ambient air-pollution * organophosphate flame-retardants * activated-receptor-gamma * aryl-hydrocarbon receptor
OECD category: Pharmacology and pharmacy
Impact factor: 5.8, year: 2022
Method of publishing: Limited access
https://www.sciencedirect.com/science/article/pii/S0006295222001095?via%3Dihub
Permanent Link: https://hdl.handle.net/11104/0340824 - 9.0558378 - BFÚ 2023 RIV US eng J - Journal Article
Lustig, R. - Collier, D. - Kassotis, C. - Roepke, T. - Kim, M. - J. - Blanc, E. - Barouki, R. - Bansal, U. - Cave, M. - Chatterjee, S. - Choudhury, M. - Gilbertson, M. - Lagadic-Gossmann, D. - Howard, S. - Lind, L. - Tomlinson, C. - Vondráček, Jan - Heindel, J. J.
Obesity I: Overview and molecular and biochemical mechanisms.
Biochemical Pharmacology. Roč. 199, MAY 2022 (2022), č. článku 115012. ISSN 0006-2952. E-ISSN 1873-2968
R&D Projects: GA ČR(CZ) GA21-00533S
Institutional support: RVO:68081707
Keywords : farnesoid-x-receptor * fatty liver-disease * mesenchymal stem-cells * body-mass index * nutrition examination survey * flutamide-metformin therapy * adipose-tissue inflammation * cardiovascular risk-factors
OECD category: Pharmacology and pharmacy
Impact factor: 5.8, year: 2022
Method of publishing: Limited access
https://www.sciencedirect.com/science/article/pii/S000629522200106X?via%3Dihub
Permanent Link: https://hdl.handle.net/11104/0340828 - 10.0556112 - BFÚ 2023 RIV NL eng J - Journal Article
Šimečková, P. - Pěnčíková, K. - Kováč, O. - Slavík, J. - Parenicova, M. - Vondráček, Jan - Machala, M.
In vitro profiling of toxic effects of environmental polycyclic aromatic hydrocarbons on nuclear receptor signaling, disruption of endogenous metabolism and induction of cellular stress.
Science of the Total Environment. Roč. 815, APR 1 2022 (2022), č. článku 151967. ISSN 0048-9697. E-ISSN 1879-1026
R&D Projects: GA ČR(CZ) GA21-00533S
Institutional support: RVO:68081707
Keywords : pregnane-x-receptor * primary human hepatocytes * aryl-hydrocarbon * estrogen-receptor * mediated activity * hepg2 cells * cross-talk * activation
OECD category: Ecology
Impact factor: 9.8, year: 2022
Method of publishing: Limited access
https://www.sciencedirect.com/science/article/pii/S0048969721070431?via%3Dihub
Permanent Link: https://hdl.handle.net/11104/0339759