Search results
- 1.0583634 - BFÚ 2024 RIV US eng J - Journal Article
Kostrhunová, Hana - McGhie, B. S. - Marková, Lenka - Nováková, Olga - Kašpárková, Jana - Aldrich-Wright, J.R. - Brabec, Viktor
Platinum(IV) Derivatives of [Pt(1iS/i,2iS/i-diaminocyclohexane)(5,6-dimethyl-1,10-phenanthroline)] with Diclofenac Ligands in the Axial Positions: A New Class of Potent Multi-action Agents Exhibiting Selectivity to Cancer Cells.
Journal of Medicinal Chemistry. Roč. 66, č. 12 (2023), s. 7894-7908. ISSN 0022-2623. E-ISSN 1520-4804
R&D Projects: GA ČR(CZ) GA21-27514S
Institutional support: RVO:68081707
Keywords : cyclooxygenase inhibitors * anticancer activity * in-vitro * death * complexes * mechanism * cisplatin * mitochondrial * cytotoxicity
OECD category: Inorganic and nuclear chemistry
Impact factor: 7.3, year: 2022
Method of publishing: Open access
https://pubs.acs.org/doi/10.1021/acs.jmedchem.3c00269
Permanent Link: https://hdl.handle.net/11104/0351654 - 2.0555336 - BFÚ 2022 RIV DE eng J - Journal Article
Shi, H. - Kašpárková, Jana - Soulie, C. - Clarkson, G.J. - Imberti, C. - Nováková, Olga - Paterson, M. - Brabec, Viktor - Sadler, P.J.
DNA-Intercalative Platinum Anticancer Complexes Photoactivated by Visible Light.
Chemistry - A European Journal. Roč. 27, č. 41 (2021), s. 10711-10716. ISSN 0947-6539. E-ISSN 1521-3765
R&D Projects: GA ČR(CZ) GA21-27514S
Institutional support: RVO:68081707
Keywords : phase-ii * 1,8-naphthalimide * cancer * conjugate * therapy
OECD category: Physical chemistry
Impact factor: 5.020, year: 2021
Method of publishing: Open access
https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/chem.202101168
Permanent Link: http://hdl.handle.net/11104/0329845 - 3.0554462 - BFÚ 2022 RIV CH eng J - Journal Article
Hreusová, Monika - Brabec, Viktor - Nováková, Olga
Processing and Bypass of a Site-Specific DNA Adduct of the Cytotoxic Platinum-Acridinylthiourea Conjugate by Polymerases Involved in DNA Repair: Biochemical and Thermodynamic Aspects.
International Journal of Molecular Sciences. Roč. 22, č. 19 (2021), č. článku 10838. E-ISSN 1422-0067
R&D Projects: GA ČR(CZ) GA21-27514S
Institutional support: RVO:68081707
Keywords : intrastrand cross-link * i klenow fragment * translesion synthesis * antitumor oxaliplatin * template-primers
OECD category: Biochemistry and molecular biology
Impact factor: 6.208, year: 2021
Method of publishing: Open access
https://www.mdpi.com/1422-0067/22/19/10838
Permanent Link: http://hdl.handle.net/11104/0329174 - 4.0536132 - BFÚ 2021 RIV CH eng J - Journal Article
Hreusová, Monika - Nováková, Olga - Brabec, Viktor
Thermodynamic Insights by Microscale Thermophoresis into Translesion DNA Synthesis Catalyzed by DNA Polymerases Across a Lesion of Antitumor Platinum-Acridine Complex.
International Journal of Molecular Sciences. Roč. 21, č. 20 (2020), č. článku 7806. E-ISSN 1422-0067
R&D Projects: GA ČR(CZ) GA18-09502S
Institutional support: RVO:68081707
Keywords : interstrand cross-links * minor-groove * bypass * mechanism * replication * recognition
OECD category: Biochemistry and molecular biology
Impact factor: 5.924, year: 2020
Method of publishing: Open access
https://apps.webofknowledge.com/full_record.do?product=WOS&search_mode=AdvancedSearch&qid=49&SID=D6z8gkVRPsT8KjTKgCD&page=1&doc=1
Permanent Link: http://hdl.handle.net/11104/0313953 - 5.0536117 - BFÚ 2021 RIV DE eng J - Journal Article
Hoeschele, J. D. - Kašpárková, Jana - Kostrhunová, Hana - Nováková, Olga - Prachařová, Jitka - Pineau, P. - Brabec, Viktor
Synthesis, antiproliferative activity in cancer cells and DNA interaction studies of [Pt(cis-1,3-diaminocycloalkane)Cl-2] analogs.
Journal of Biological Inorganic Chemistry. Roč. 25, č. 6 (2020), s. 913-924. ISSN 0949-8257. E-ISSN 1432-1327
R&D Projects: GA MŠMT(CZ) LTAUSA18009
Institutional support: RVO:68081707
Keywords : oxaliplatin * kiteplatin * cisplatin * derivatives * selectivity * complexes * agents
OECD category: Biochemistry and molecular biology
Impact factor: 3.358, year: 2020
Method of publishing: Limited access
https://link.springer.com/article/10.1007/s00775-020-01809-9
Permanent Link: http://hdl.handle.net/11104/0313944 - 6.0518335 - BFÚ 2020 RIV NL eng J - Journal Article
Hreusová, Monika - Nováková, Olga - Kostrhunová, Hana - Prachařová, J. - Brabec, Viktor - Kašpárková, Jana
DNA modification by cisplatin-like Pt(II) complexes containing 1,1 '-binaphtyl-2,2 '-diamine ligand does not correlate with their antiproliferative activity in cancer cells.
Inorganica chimica acta. Roč. 495, SEP 1 2019 (2019), č. článku 118952. ISSN 0020-1693. E-ISSN 1873-3255
R&D Projects: GA ČR(CZ) GA18-09502S
Institutional support: RVO:68081707
Keywords : interstrand cross-links * supercoiled dna * repair * polynucleotides * conformation
OECD category: Inorganic and nuclear chemistry
Impact factor: 2.304, year: 2019
Method of publishing: Limited access
https://www.sciencedirect.com/science/article/abs/pii/S0020169319305912?via%3Dihub
Permanent Link: http://hdl.handle.net/11104/0303498 - 7.0518313 - BFÚ 2020 RIV CH eng J - Journal Article
Hrabina, Ondřej - Brabec, Viktor - Nováková, Olga
Translesion DNA Synthesis Across Lesions Induced by Oxidative Products of Pyrimidines: An Insight into the Mechanism by Microscale Thermophoresis.
International Journal of Molecular Sciences. Roč. 20, č. 20 (2019), č. článku 5012. E-ISSN 1422-0067
R&D Projects: GA ČR GA17-09436S
Institutional support: RVO:68081707
Keywords : i klenow fragment * polymerase-i * cross-links * abasic site * base-pairs
OECD category: Biochemistry and molecular biology
Impact factor: 4.556, year: 2019
Method of publishing: Open access
https://www.mdpi.com/1422-0067/20/20/5012/pdf
Permanent Link: http://hdl.handle.net/11104/0303475 - 8.0502569 - BFÚ 2019 RIV GB eng J - Journal Article
Nováková, Olga - Farrell, N.P. - Brabec, Viktor
Translesion DNA synthesis across double-base lesions derived from cross-links of an antitumor trinuclear platinum compound: primer extension, conformational and thermodynamic studies.
Metallomics. Roč. 10, č. 1 (2018), s. 132-144. ISSN 1756-5901. E-ISSN 1756-591X
R&D Projects: GA ČR GA17-09436S
Institutional support: RVO:68081707
Keywords : group domain proteins * i klenow fragment * polymerase-i * duplex dna
OECD category: Biochemistry and molecular biology
Impact factor: 3.571, year: 2018
Permanent Link: http://hdl.handle.net/11104/0294472 - 9.0501669 - BFÚ 2019 US eng J - Journal Article
Shi, H. - Romero-Canelon, I. - Hreusová, Monika - Nováková, Olga - Venkatesh, V. - Habtemariam, A. - Clarkson, G.J. - Song, J.I. - Brabec, Viktor - Sadler, P.J.
Photoactivatable Cell-Selective Dinuclear trans-Diazidoplatinum(IV) Anticancer Prodrugs.
Inorganic Chemistry. Roč. 57, č. 22 (2018), s. 14409-14420. ISSN 0020-1669. E-ISSN 1520-510X
Institutional support: RVO:68081707
Keywords : interstrand cross-links * trinuclear platinum complex * photodynamic therapy * amine compounds
Impact factor: 4.850, year: 2018
Permanent Link: http://hdl.handle.net/11104/0293683 - 10.0471985 - BFÚ 2022 GB eng J - Journal Article
Brabec, Viktor - Vrána, Oldřich - Nováková, Olga - Kašpárková, Jana
Comment on ´Delivering a photosensitive transplatin prodrug to overcome cisplatin drug resistance´ by H. Song, W. Li, R. Qi, L. Yan, X. Jing, M. Zheng and H. Xiao, Chem. Commun., 2015, 51, 11493.
2016. Chemical Communications. Roč. 52, č. 21 (2016), s. 4096-4098. ISSN 1359-7345. E-ISSN 1364-548X
Institutional support: RVO:68081707
Keywords : interstrand cross-links * dna * platinum
OECD category: Physical chemistry
Impact factor: 6.319, year: 2016
Method of publishing: Limited access
https://pubs.rsc.org/en/content/articlelanding/2016/CC/C5CC09589A
Permanent Link: http://hdl.handle.net/11104/0269344