Search results
- 1.0583634 - BFÚ 2024 RIV US eng J - Journal Article
Kostrhunová, Hana - McGhie, B. S. - Marková, Lenka - Nováková, Olga - Kašpárková, Jana - Aldrich-Wright, J.R. - Brabec, Viktor
Platinum(IV) Derivatives of [Pt(1iS/i,2iS/i-diaminocyclohexane)(5,6-dimethyl-1,10-phenanthroline)] with Diclofenac Ligands in the Axial Positions: A New Class of Potent Multi-action Agents Exhibiting Selectivity to Cancer Cells.
Journal of Medicinal Chemistry. Roč. 66, č. 12 (2023), s. 7894-7908. ISSN 0022-2623. E-ISSN 1520-4804
R&D Projects: GA ČR(CZ) GA21-27514S
Institutional support: RVO:68081707
Keywords : cyclooxygenase inhibitors * anticancer activity * in-vitro * death * complexes * mechanism * cisplatin * mitochondrial * cytotoxicity
OECD category: Inorganic and nuclear chemistry
Impact factor: 7.3, year: 2022
Method of publishing: Open access
https://pubs.acs.org/doi/10.1021/acs.jmedchem.3c00269
Permanent Link: https://hdl.handle.net/11104/0351654 - 2.0583469 - BFÚ 2024 RIV IE eng J - Journal Article
Bresciani, G. - Červinka, Jakub - Kostrhunová, Hana - Biancalana, L. - Bortoluzzi, M. - Pampaloni, G. - Novohradský, Vojtěch - Brabec, Viktor - Marchetti, F. - Kašpárková, Jana
N-Indolyl diiron vinyliminium complexes exhibit antiproliferative effects in cancer cells associated with disruption of mitochondrial homeostasis, ROS scavenging, and antioxidant activity.
Chemico-Biological Interactions. Roč. 385, NOV 1 2023 (2023), č. článku 110742. ISSN 0009-2797. E-ISSN 1872-7786
R&D Projects: GA ČR(CZ) GA23-06316S
Institutional support: RVO:68081707
Keywords : basis-sets * mechanisms * cisplatin * molecules * drugs * oxaliplatin * insertion * energies
OECD category: Biochemistry and molecular biology
Impact factor: 5.1, year: 2022
Method of publishing: Open access
https://www.sciencedirect.com/science/article/pii/S000927972300409X?via%3Dihub
Permanent Link: https://hdl.handle.net/11104/0351439 - 3.0582097 - BFÚ 2024 RIV US eng J - Journal Article
Kašpárková, Jana - Hernandez-Garcia, A. - Kostrhunová, Hana - Goicuria, M. - Novohradský, Vojtěch - Bautista, D. - Marková, Lenka - Santana, M.D. - Brabec, Viktor - Ruiz, J.
Novel 2-(5-Arylthiophen-2-yl)-benzoazole Cyclometalated Iridium(III) dppz Complexes Exhibit Selective Phototoxicity in Cancer Cells by Lysosomal Damage and Oncosis.
Journal of Medicinal Chemistry. Roč. 67, č. 1 (2023), s. 691-708. ISSN 0022-2623. E-ISSN 1520-4804
R&D Projects: GA ČR(CZ) GA23-06316S
Institutional support: RVO:68081707
Keywords : photodynamic anticancer * carbene complexes * apoptosis * therapy * necrosis
OECD category: Pharmacology and pharmacy
Impact factor: 7.3, year: 2022
Method of publishing: Open access
https://pubs.acs.org/doi/10.1021/acs.jmedchem.3c01978
Permanent Link: https://hdl.handle.net/11104/0350372 - 4.0577353 - BFÚ 2024 RIV DE eng J - Journal Article
Sarkar, A. - Novohradský, Vojtěch - Maji, M. - Babu, T. - Marková, Lenka - Kostrhunová, Hana - Kašpárková, Jana - Gandin, V. - Brabec, Viktor - Gibson, D.
Multitargeting Prodrugs that Release Oxaliplatin, Doxorubicin and Gemcitabine are Potent Inhibitors of Tumor Growth and Effective Inducers of Immunogenic Cell Death.
Angewandte Chemie - International Edition. Roč. 62, č. 42 (2023). ISSN 1433-7851. E-ISSN 1521-3773
R&D Projects: GA ČR(CZ) GA23-06307S
Institutional support: RVO:68081707
Keywords : Doxorubicin * Gemcitabine * Immunogenic Cell Death * Multi-Targeting Prodrugs * Oxaliplatin
OECD category: Immunology
Impact factor: 16.6, year: 2022
Method of publishing: Open access
https://onlinelibrary.wiley.com/doi/epdf/10.1002/anie.202310774
Permanent Link: https://hdl.handle.net/11104/0349137 - 5.0572135 - BFÚ 2024 RIV US eng J - Journal Article
Hernandez-Garcia, A. - Marková, Lenka - Santana, M.D. - Prachařová, Jitka - Bautista, D. - Kostrhunová, Hana - Novohradský, Vojtěch - Brabec, Viktor - Ruiz, J. - Kašpárková, Jana
Cyclometalated Benzimidazole Osmium(II) Complexes with Antiproliferative Activity in Cancer Cells Disrupt Calcium Homeostasis.
Inorganic Chemistry. Roč. 62, č. 16 (2023), s. 6474-6487. ISSN 0020-1669. E-ISSN 1520-510X
R&D Projects: GA ČR(CZ) GA23-06316S
Institutional support: RVO:68081707
Keywords : ANTICANCER COMPLEXES * PHOTOSENSITIZERS * RUTHENIUM(II)
OECD category: Inorganic and nuclear chemistry
Impact factor: 4.6, year: 2022
Method of publishing: Open access
https://pubs.acs.org/doi/10.1021/acs.inorgchem.3c00501
Permanent Link: https://hdl.handle.net/11104/0350010 - 6.0560259 - BFÚ 2023 RIV US eng J - Journal Article
Červinka, Jakub - Gobbo, A. - Biancalana, L. - Marková, Lenka - Novohradský, Vojtěch - Guelfi, M. - Zacchini, S. - Kašpárková, Jana - Brabec, Viktor - Marchetti, F.
Ruthenium(II)-Tris-pyrazolylmethane Complexes Inhibit Cancer Cell Growth by Disrupting Mitochondrial Calcium Homeostasis.
Journal of Medicinal Chemistry. Roč. 65, č. 15 (2022), s. 10567-10587. ISSN 0022-2623. E-ISSN 1520-4804
R&D Projects: GA ČR(CZ) GA21-27514S
Institutional support: RVO:68081707
Keywords : ARENE COMPLEXES * TRIS(PYRAZOLYL)METHANE LIGANDS * CONDUCTIVITY MEASUREMENTS
OECD category: Pharmacology and pharmacy
Impact factor: 7.3, year: 2022
Method of publishing: Open access
https://pubs.acs.org/doi/10.1021/acs.jmedchem.2c00722
Permanent Link: https://hdl.handle.net/11104/0340532 - 7.0560039 - BFÚ 2023 RIV US eng J - Journal Article
Hreusová, Monika - Novohradský, Vojtěch - Marková, Lenka - Kostrhunová, Hana - Potočňák, I. - Brabec, Viktor - Kašpárková, Jana
Gallium(III) Complex with Cloxyquin Ligands Induces Ferroptosis in Cancer Cells and Is a Potent Agent against Both Differentiated and Tumorigenic Cancer Stem Rhabdomyosarcoma Cells.
Bioinorganic Chemistry and Applications. Roč. 2022, APR 23 2022 (2022), č. článku 3095749. ISSN 1565-3633. E-ISSN 1687-479X
R&D Projects: GA ČR(CZ) GA21-27514S
Institutional support: RVO:68081707
Keywords : TRIS(8-QUINOLINOLATO)GALLIUM(III) * THIOSEMICARBAZONES * POLYPHARMACOLOGY * ANTITUMOR * KP46
OECD category: Biochemistry and molecular biology
Impact factor: 3.8, year: 2022
Method of publishing: Open access
https://www.hindawi.com/journals/bca/2022/3095749/
Permanent Link: https://hdl.handle.net/11104/0340536 - 8.0559611 - BFÚ 2023 RIV GB eng J - Journal Article
Kašpárková, Jana - Kostrhunová, Hana - Novohradský, Vojtěch - Ma, L. - Zhu, G. - Milaeva, E. R. - Shtill, A. A. - Vinck, R. - Gasser, G. - Brabec, Viktor - Nazarov, A. A.
Is antitumor Pt(IV) complex containing two axial lonidamine ligands a true dual- or multi-action prodrug?
Metallomics. Roč. 14, č. 7 (2022), č. článku mfac048. ISSN 1756-5901. E-ISSN 1756-591X
R&D Projects: GA ČR(CZ) GC20-14082J
Institutional support: RVO:68081707
Keywords : bioinorganic chemistry * lonidamine * medicinal inorganic chemistry * metals in medicine * Pt(IV) complexes
OECD category: Biochemistry and molecular biology
Impact factor: 3.4, year: 2022
Method of publishing: Open access
https://academic.oup.com/metallomics/article/14/7/mfac048/6618656?login=true
Permanent Link: https://hdl.handle.net/11104/0340502 - 9.0558795 - BFÚ 2023 RIV GB eng J - Journal Article
Novohradský, Vojtěch - Marková, Lenka - Kostrhunová, Hana - Svitelova, M. - Kašpárková, Jana - Barbanente, A. - Papadia, p. - Margiotta, N. - Hoeschele, J. D. - Brabec, Viktor
Pt(II) complex containing the 1R,2R enantiomer of trans-1,2-diamino-4-cyclohexene ligand effectively and selectively inhibits the viability of aggressive pancreatic adenocarcinoma cells and alters their lipid metabolism.
Inorganic Chemistry Frontiers. Roč. 9, č. 13 (2022), s. 3295-3305. ISSN 2052-1553. E-ISSN 2052-1553
R&D Projects: GA MŠMT(CZ) LTAUSA18009
Institutional support: RVO:68081707
Keywords : cancer-cells * er stress * lipogenesis * droplets * agents * proteins * accumulation
OECD category: Cell biology
Impact factor: 7, year: 2022
Method of publishing: Limited access
https://pubs.rsc.org/en/content/articlelanding/2022/QI/D2QI00778A
Permanent Link: https://hdl.handle.net/11104/0340483 - 10.0557968 - BFÚ 2023 RIV IE eng J - Journal Article
Marková, Lenka - Novohradský, Vojtěch - Kašpárková, Jana - Ruiz, J. - Brabec, Viktor
Dipyridophenazine iridium(III) complex as a phototoxic cancer stem cell selective, mitochondria targeting agent.
Chemico-Biological Interactions. Roč. 360, JUN 1 2022 (2022), č. článku 109955. ISSN 0009-2797. E-ISSN 1872-7786
R&D Projects: GA ČR(CZ) GA21-27514S
Institutional support: RVO:68081707
Keywords : photodynamic therapy * carbene complexes * metal-complexes * anticancer * drug * culture * 2d
OECD category: Biochemistry and molecular biology
Impact factor: 5.1, year: 2022
Method of publishing: Limited access
https://www.sciencedirect.com/science/article/pii/S0009279722001600?via%3Dihub
Permanent Link: https://hdl.handle.net/11104/0339562