Search results
- 1.0585892 - ÚMCH 2025 RIV US eng J - Journal Article
Sansee, A. - Kostka, Libor - Marcalíková, Adéla - Kudláčová, Júlia - Sedlák, František - Kotrchová, Lenka - Šácha, Pavel - Etrych, Tomáš - Kielar, F.
Iridium-based polymeric multifunctional imaging tools for biochemistry.
ChemPlusChem. Roč. 89, č. 5 (2024), č. článku e202300647. ISSN 2192-6506. E-ISSN 2192-6506
R&D Projects: GA ČR(CZ) GA23-05642S; GA MŠMT LX22NPO5102
Institutional support: RVO:61389013 ; RVO:61388963
Keywords : HPMA * iridium complex * imaging
OECD category: Polymer science; Medicinal chemistry (UOCHB-X)
Impact factor: 3.4, year: 2022
Method of publishing: Open access
https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/cplu.202300647
Permanent Link: https://hdl.handle.net/11104/0353702 - 2.0583976 - ÚOCHB 2025 RIV US eng J - Journal Article
Sedlák, František - Kvasnička, A. - Marešová, Barbora - Brumarová, R. - Dobešová, D. - Dostálová, K. - Šrámková, Karolína - Pehr, Martin - Šácha, Pavel - Friedecký, D. - Konvalinka, Jan
Parallel Metabolomics and Lipidomics of a PSMA/GCPII Deficient Mouse Model Reveal Alteration of NAAG Levels and Brain Lipid Composition.
ACS Chemical Neuroscience. Roč. 15, č. 7 (2024), s. 1342-1355. ISSN 1948-7193. E-ISSN 1948-7193
R&D Projects: GA ČR(CZ) GA21-04166S; GA MŠMT LX22NPO5102
Institutional support: RVO:61388963
Keywords : lipidomics * metabolomics * N-acetyl-aspartyl-glutamate * glutamatecarboxypeptidase II * folh1 * folyl-poly-gamma-glutamylhydrolase I
Impact factor: 5, year: 2022
Method of publishing: Open access
https://doi.org/10.1021/acschemneuro.3c00494
Permanent Link: https://hdl.handle.net/11104/0351973File Download Size Commentary Version Access 10.1021acschemneuro.3c00494.pdf 0 4.6 MB Publisher’s postprint open-access - 3.0582834 - ÚMCH 2025 RIV US eng J - Journal Article
Elter, Johanna K. - Liščáková, Veronika - Moravec, Oliver - Vragović, Martina - Filipová, Marcela - Štěpánek, Petr - Šácha, Pavel - Hrubý, Martin
Solid-phase synthesis as a tool to create exactly defined, branched polymer vectors for cell membrane targeting.
Macromolecules. Roč. 57, č. 3 (2024), s. 1050-1071. ISSN 0024-9297. E-ISSN 1520-5835
R&D Projects: GA ČR(CZ) GA21-04166S; GA MŠMT LX22NPO5102; GA MZd(CZ) NU22-03-00318
Institutional support: RVO:61389013 ; RVO:61388963
Keywords : peptoids * sequence-defined polymer * solid-phase synthesis
OECD category: Polymer science; Medicinal chemistry (UOCHB-X)
Impact factor: 5.5, year: 2022
Method of publishing: Open access
https://pubs.acs.org/doi/10.1021/acs.macromol.3c02600
Permanent Link: https://hdl.handle.net/11104/0351055File Download Size Commentary Version Access 0582834.pdf 0 15.1 MB License CC-BY 4.0 Publisher’s postprint open-access - 4.0577780 - ÚOCHB 2024 RIV GB eng J - Journal Article
Kertisová, Anna - Žáková, Lenka - Macháčková, Kateřina - Marek, Aleš - Šácha, Pavel - Pompach, Petr - Jiráček, Jiří - Selicharová, Irena
Insulin receptor Arg717 and IGF-1 receptor Arg704 play a key role in ligand binding and in receptor activation.
Open Biology. Roč. 13, č. 11 (2023), č. článku 230142. E-ISSN 2046-2441
R&D Projects: GA MŠMT(CZ) LX22NPO5104; GA MŠMT(CZ) EF16_019/0000729; GA ČR(CZ) GA22-17978S; GA MŠMT(CZ) EF18_046/0015974; GA MŠMT LM2023042
Institutional support: RVO:61388963 ; RVO:86652036
Keywords : mutagenesisin vitro * peptide hormone * eceptor modification * eceptor tyrosine kinase * structure–function
OECD category: Biochemistry and molecular biology
Impact factor: 5.8, year: 2022
Method of publishing: Open access
https://doi.org/10.1098/rsob.230142
Permanent Link: https://hdl.handle.net/11104/0346886File Download Size Commentary Version Access 10.1098rsob.230142.pdf 2 2 MB Publisher’s postprint open-access - 5.0575786 - ÚMCH 2024 RIV NL eng J - Journal Article
Lobaz, Volodymyr - Liščáková, Veronika - Sedlák, František - Musil, Dominik - Lukáš Petrova, Svetlana - Šeděnková, Ivana - Pánek, Jiří - Kučka, Jan - Konefal, Rafal - Tihlaříková, Eva - Neděla, Vilém - Pankrác, J. - Šefc, L. - Hrubý, Martin - Šácha, Pavel - Štěpánek, Petr
Tuning polymer-blood and polymer-cytoplasm membrane interactions by manipulating the architecture of poly(2-oxazoline) triblock copolymers.
Colloids and Surfaces B-Biointerfaces. Roč. 231, November (2023), č. článku 113564. ISSN 0927-7765. E-ISSN 1873-4367
R&D Projects: GA MZd(CZ) NU22-03-00318; GA ČR(CZ) GA21-04166S; GA ČR(CZ) GA22-25799S; GA MŠMT LX22NPO5102; GA MŠMT(CZ) LM2023053
Institutional support: RVO:61389013 ; RVO:61388963 ; RVO:68081731
Keywords : amphiphilic triblock polyoxazoline * drug delivery * blood proteins
OECD category: Polymer science; Biochemistry and molecular biology (UOCHB-X); Electrical and electronic engineering (UPT-D)
Impact factor: 5.8, year: 2022
Method of publishing: Open access
https://www.sciencedirect.com/science/article/pii/S0927776523004423?via%3Dihub
Permanent Link: https://hdl.handle.net/11104/0345639File Download Size Commentary Version Access 0575786.pdf 5 2.3 MB CC BY License Publisher’s postprint open-access - 6.0571308 - ÚOCHB 2024 RIV NL eng J - Journal Article
Freitas-Lima, Leandro Ceotto - Pačesová, Andrea - Staňurová, Jana - Šácha, Pavel - Marek, Aleš - Hubálek, Martin - Kuneš, Jaroslav - Železná, Blanka - Maletínská, Lenka
GPR160 is not a receptor of anorexigenic cocaine- and amphetamine-regulated transcript peptide.
European Journal of Pharmacology. Roč. 949, June (2023), č. článku 175713. ISSN 0014-2999. E-ISSN 1879-0712
R&D Projects: GA MŠMT(CZ) LX22NPO5104; GA ČR(CZ) GA23-05642S
Institutional support: RVO:61388963
Keywords : binding assay * CARTp * GPCR * GPR160 * transfection
OECD category: Pharmacology and pharmacy
Impact factor: 5, year: 2022
Method of publishing: Open access
https://doi.org/10.1016/j.ejphar.2023.175713
Permanent Link: https://hdl.handle.net/11104/0342562File Download Size Commentary Version Access 10.1016j.ejphar.2023.175713.pdf 2 5.1 MB Publisher’s postprint open-access - 7.0547609 - ÚOCHB 2022 RIV US eng J - Journal Article
Blažková, Kristýna - Beranová, Jana - Hradilek, Martin - Kostka, Libor - Šubr, Vladimír - Etrych, Tomáš - Šácha, Pavel - Konvalinka, Jan
The Development of a High-Affinity Conformation-Sensitive Antibody Mimetic Using a Biocompatible Copolymer Carrier (iBody).
Journal of Biological Chemistry. Roč. 297, č. 5 (2021), č. článku 101342. ISSN 0021-9258. E-ISSN 1083-351X
R&D Projects: GA ČR(CZ) GA21-04166S; GA ČR(CZ) GA19-05649S; GA MŠMT(CZ) EF16_019/0000729
Institutional support: RVO:61388963 ; RVO:61389013
Keywords : antibody mimetics * bicyclic phage display * molecular recognition * HPMA copolymer * PSMA * phage display * cyclic peptide * protein targeting * nanotechnology * chemical biology
OECD category: Biochemistry and molecular biology; Polymer science (UMCH-V)
Impact factor: 5.485, year: 2021
Method of publishing: Open access
https://doi.org/10.1016/j.jbc.2021.101342
Permanent Link: http://hdl.handle.net/11104/0323818 - 8.0547173 - ÚMCH 2022 RIV GB eng J - Journal Article
Šubr, Vladimír - Ormsby, Tereza - Šácha, Pavel - Konvalinka, Jan - Etrych, Tomáš - Kostka, Libor
The role of the biotin linker in polymer antibody mimetics, iBodies, in biochemical assays.
Polymer Chemistry. Roč. 12, č. 41 (2021), s. 6009-6021. ISSN 1759-9954. E-ISSN 1759-9962
R&D Projects: GA ČR(CZ) GA19-05649S; GA ČR(CZ) GA19-10280S; GA MŠMT(CZ) EF16_019/0000729
Institutional support: RVO:61389013 ; RVO:61388963
Keywords : HPMA * iBody * biotin
OECD category: Polymer science; Biochemical research methods (UOCHB-X)
Impact factor: 5.364, year: 2021
Method of publishing: Limited access
https://pubs.rsc.org/en/content/articlelanding/2021/PY/D1PY00707F
Permanent Link: http://hdl.handle.net/11104/0324045 - 9.0544791 - ÚOCHB 2022 RIV FR eng J - Journal Article
Šimková, Adéla - Ormsby, Tereza - Sidej, Natan - Poštová Slavětínská, Lenka - Brynda, Jiří - Beranová, Jana - Šácha, Pavel - Majer, Pavel - Konvalinka, Jan
Structure-activity relationship and biochemical evaluation of novel fibroblast activation protein and prolyl endopeptidase inhibitors with α-ketoamide warheads.
European Journal of Medicinal Chemistry. Roč. 224, Nov 15 (2021), č. článku 113717. ISSN 0223-5234. E-ISSN 1768-3254
R&D Projects: GA ČR(CZ) GA19-10280S; GA MZd(CZ) NV15-31379A; GA MŠMT(CZ) EF16_019/0000729; GA MŠMT(CZ) LM2015064
Institutional support: RVO:61388963
Keywords : fibroblast activation protein * seprase * FAP inhibitor * serine protease inhibition * prolyl endopeptidase * α-Ketoamide inhibitor
OECD category: Medicinal chemistry
Impact factor: 7.088, year: 2021
Method of publishing: Open access
https://doi.org/10.1016/j.ejmech.2021.113717
Permanent Link: http://hdl.handle.net/11104/0321598 - 10.0543118 - ÚOCHB 2022 RIV US eng J - Journal Article
Kryštůfek, Robin - Šácha, Pavel - Starková, Jana - Brynda, Jiří - Hradilek, Martin - Tloušťová, Eva - Grzymska, J. - Rut, W. - Boucher, M. J. - Drag, M. - Majer, Pavel - Hájek, Miroslav - Řezáčová, Pavlína - Madhani, H. D. - Craik, C. S. - Konvalinka, Jan
Re-emerging Aspartic Protease Targets: Examining Cryptococcus neoformans Major Aspartyl Peptidase 1 as a Target for Antifungal Drug Discovery.
Journal of Medicinal Chemistry. Roč. 64, č. 10 (2021), s. 6706-6719. ISSN 0022-2623. E-ISSN 1520-4804
R&D Projects: GA MŠMT(CZ) EF16_019/0000729
Institutional support: RVO:61388963
Keywords : immunodeficiency virus HIV * in-vitro * virulence factors
OECD category: Medicinal chemistry
Impact factor: 8.039, year: 2021
Method of publishing: Open access
https://doi.org/10.1021/acs.jmedchem.0c02177
Permanent Link: http://hdl.handle.net/11104/0320402