Search results
- 1.0584443 - ÚOCHB 2025 RIV US eng J - Journal Article
Hanzlová, M. - Slavíková, Barbora - Morozovová, Marina - Musílek, K. - Rotterová, A. - Zemanová, L. - Kudová, Eva
C-3 Steroidal Hemiesters as Inhibitors of 17β-Hydroxysteroid Dehydrogenase Type 10.
ACS Omega. Roč. 9, č. 10 (2024), s. 12116-12124. ISSN 2470-1343. E-ISSN 2470-1343
Institutional support: RVO:61388963
Keywords : alzheimers-disease * design * roles
Impact factor: 4.1, year: 2022
Method of publishing: Open access
https://doi.org/10.1021/acsomega.3c10148
Permanent Link: https://hdl.handle.net/11104/0352357 - 2.0584427 - FGÚ 2025 RIV GB eng J - Journal Article
Cheema, Marie Munawar - Kotrbová Macáková, Zuzana - Hrčka Krausová, Barbora - Adla, Santosh Kumar - Slavíková, Barbora - Chodounská, Hana - Kratochvíl, Miroslav - Vondrášek, Jiří - Sedlák, David - Balaštík, Martin - Kudová, Eva
5β-reduced neuroactive steroids as modulators of growth and viability of postnatal neurons and glia.
Journal of Steroid Biochemistry and Molecular Biology. Roč. 239, May (2024), č. článku 106464. ISSN 0960-0760
R&D Projects: GA MŠMT(CZ) LX22NPO5107; GA MZd(CZ) NV18-04-00085; GA ČR(CZ) GA21-24571S
Research Infrastructure: CZ-OPENSCREEN III - 90130; CZ-OPENSCREEN II - 90063; CCP II - 90126
Institutional support: RVO:67985823 ; RVO:61388963 ; RVO:68378050
Keywords : neurosteroids * neuroactive steroids * neurite growth * computational analysis * myelin basic protein * high-content screening
OECD category: Clinical neurology
Impact factor: 4.1, year: 2022
https://doi.org/10.1016/j.jsbmb.2024.106464
Permanent Link: https://hdl.handle.net/11104/0352546 - 3.0558330 - ÚOCHB 2023 RIV NL eng J - Journal Article
Voldřich, Jan - Matoušová, Marika - Šmídková, Markéta - Slavíková, Barbora - Chodounská, Hana - Kudová, Eva - Mertlíková-Kaiserová, Helena
Identification of N-methyl-D-aspartate receptor antagonists using the rat postnatal mixed cortical and hippocampal neurons.
European Journal of Pharmacology. Roč. 927, July (2022), č. článku 175056. ISSN 0014-2999. E-ISSN 1879-0712
R&D Projects: GA TA ČR(CZ) TN01000013
Institutional support: RVO:61388963
Keywords : NMDA receptors * primary neurons * iPSC * neurosteroids
OECD category: Biochemistry and molecular biology
Impact factor: 5, year: 2022
Method of publishing: Limited access
https://doi.org/10.1016/j.ejphar.2022.175056
Permanent Link: http://hdl.handle.net/11104/0332052 - 4.0532987 - FGÚ 2021 RIV GB eng J - Journal Article
Sivčev, Sonja - Slavíková, Barbora - Ivetic, Milorad - Knězů, Michal - Kudová, Eva - Zemková, Hana
Lithocholic acid inhibits P2X2 and potentiates P2X4 receptor channel gating.
Journal of Steroid Biochemistry and Molecular Biology. Roč. 202, Sep (2020), č. článku 105725. ISSN 0960-0760
R&D Projects: GA ČR(CZ) GA18-05413S; GA MŠMT(CZ) LQ1604; GA MŠMT(CZ) ED1.1.00/02.0109
Institutional support: RVO:67985823 ; RVO:61388963
Keywords : ATP * purinergic P2X receptors * bile acids * lithocholic acid * ivermectin * allosteric modulation
OECD category: Neurosciences (including psychophysiology; Neurosciences (including psychophysiology (UOCHB-X)
Impact factor: 4.294, year: 2020
Method of publishing: Limited access
https://doi.org/10.1016/j.jsbmb.2020.105725
Permanent Link: http://hdl.handle.net/11104/0311490 - 5.0507827 - FGÚ 2020 RIV US eng J - Journal Article
Sivčev, Sonja - Slavíková, Barbora - Rupert, Marian - Ivetic, Milorad - Nekardová, Michaela - Kudová, Eva - Zemková, Hana
Synthetic testosterone derivatives modulate rat P2X2 and P2X4 receptor channel gating.
Journal of Neurochemistry. Roč. 150, č. 1 (2019), s. 28-43. ISSN 0022-3042. E-ISSN 1471-4159
R&D Projects: GA ČR(CZ) GA16-12695S; GA ČR(CZ) GA18-05413S; GA ČR(CZ) GBP208/12/G016; GA MŠMT(CZ) LQ1604; GA MŠMT(CZ) ED1.1.00/02.0109
Institutional support: RVO:67985823 ; RVO:61388963
Keywords : allosteric modulation * ATP * P2XR * testosterone derivatives * purinergic receptors * ivermectin
OECD category: Neurosciences (including psychophysiology
Impact factor: 4.066, year: 2019
Method of publishing: Open access with time embargo
https://doi.org/10.1111/jnc.14718
Permanent Link: http://hdl.handle.net/11104/0298791 - 6.0505510 - ÚOCHB 2020 RIV GB eng J - Journal Article
Šmídková, Markéta - Hájek, Miroslav - Adla, Santosh Kumar - Slavíková, Barbora - Chodounská, Hana - Matoušová, Marika - Mertlíková-Kaiserová, Helena - Kudová, Eva
Screening of novel 3 alpha 5 beta-neurosteroids for neuroprotective activity against glutamate- or NMDA-induced excitotoxicity.
Journal of Steroid Biochemistry and Molecular Biology. Roč. 189, May (2019), s. 195-203. ISSN 0960-0760
R&D Projects: GA TA ČR(CZ) TE01020028; GA MŠMT LO1302; GA TA ČR(CZ) TN01000013
Institutional support: RVO:61388963
Keywords : neurosteroids * NMDAR * glutamate excitotoxicity * neuroprotection
OECD category: Biochemistry and molecular biology
Impact factor: 3.813, year: 2019
Method of publishing: Limited access
https://www.sciencedirect.com/science/article/abs/pii/S0960076019300378?via%3Dihub
Permanent Link: http://hdl.handle.net/11104/0296991 - 7.0501437 - ÚOCHB 2020 RIV US eng J - Journal Article
Matoušová, Marika - Souček, Radko - Tloušťová, Eva - Slavíková, Barbora - Chodounská, Hana - Mertlíková-Kaiserová, Helena - Kudová, Eva
Pregn-5-en-3beta-ol and androst-5-en-3beta-ol dicarboxylic acid esters as potential therapeutics for NMDA hypofunction: In vitro safety assessment and plasma stability.
Steroids. Roč. 147, Jul (2019), s. 4-9. ISSN 0039-128X. E-ISSN 1878-5867
R&D Projects: GA ČR(CZ) GA17-02300S; GA MZd(CZ) NV15-29370A; GA MŠMT LO1302
Institutional support: RVO:61388963
Keywords : neurosteroid * NMDA receptor hypofunction * hepatotoxicity * mitotoxicity * Caco-2 permeability * plasma stability
OECD category: Neurosciences (including psychophysiology
Impact factor: 1.948, year: 2019
Method of publishing: Limited access
https://www.sciencedirect.com/science/article/abs/pii/S0039128X18301752?via%3Dihub
Permanent Link: http://hdl.handle.net/11104/0296235 - 8.0498559 - ÚOCHB 2019 RIV CH eng J - Journal Article
Adla, Santosh Kumar - Slavíková, Barbora - Chodounská, Hana - Vyklický, Vojtěch - Ladislav, Marek - Hubálková, Pavla - Krausová, Barbora - Smejkalová, Tereza - Nekardová, Michaela - Šmídková, Markéta - Monincová, Lenka - Souček, Radko - Vyklický ml., Ladislav - Kudová, Eva
Strong Inhibitory Effect, Low Cytotoxicity and High Plasma Stability of Steroidal Inhibitors of N-Methyl-D-Aspartate Receptors With C-3 Amide Structural Motif.
Frontiers in Pharmacology. Roč. 9, Nov 12 (2018), č. článku 1299. ISSN 1663-9812. E-ISSN 1663-9812
R&D Projects: GA TA ČR(CZ) TE01020028; GA ČR(CZ) GBP208/12/G016; GA ČR(CZ) GA17-02300S; GA ČR(CZ) GJ16-03913Y; GA MZd(CZ) NV15-29370A; GA MŠMT LO1302; GA MŠMT(CZ) ED1.1.00/02.0109
Grant - others:AV ČR(CZ) MSM200111601
Program: Program na podporu mezinárodní spolupráce začínajících výzkumných pracovníků
Institutional support: RVO:61388963 ; RVO:67985823
Keywords : neurosteroid * amide * NMDA receptor * plasma stability * structure-activity relationship
OECD category: Biochemistry and molecular biology
Impact factor: 3.845, year: 2018
https://www.frontiersin.org/articles/10.3389/fphar.2018.01299/full
Permanent Link: http://hdl.handle.net/11104/0291127 - 9.0490287 - FGÚ 2019 RIV US eng J - Journal Article
Krausová, Barbora - Slavíková, Barbora - Nekardová, Michaela - Hubálková, Pavla - Vyklický, Vojtěch - Chodounská, Hana - Vyklický ml., Ladislav - Kudová, Eva
Positive Modulators of the N-Methyl-D-aspartate Receptor: Structure-Activity Relationship Study of Steroidal 3-Hemiesters.
Journal of Medicinal Chemistry. Roč. 61, č. 10 (2018), s. 4505-4516. ISSN 0022-2623. E-ISSN 1520-4804
R&D Projects: GA ČR(CZ) GA17-02300S; GA ČR(CZ) GBP208/12/G016; GA TA ČR(CZ) TE01020028; GA MZd(CZ) NV15-29370A; GA MŠMT(CZ) ED1.1.00/02.0109
Grant - others:AV ČR(CZ) MSM200111601
Program: Program na podporu mezinárodní spolupráce začínajících výzkumných pracovníků
Institutional support: RVO:67985823 ; RVO:61388963
Keywords : neurosteroids * N-Methyl-D-aspartate receptor * positive modulators
OECD category: Neurosciences (including psychophysiology
Impact factor: 6.054, year: 2018
Permanent Link: http://hdl.handle.net/11104/0284547 - 10.0474432 - ÚOCHB 2018 RIV US eng J - Journal Article
Adla, Santosh Kumar - Slavíková, Barbora - Šmídková, Markéta - Tloušťová, Eva - Svoboda, Martin - Vyklický, Vojtěch - Krausová, Barbora - Hubálková, Pavla - Nekardová, Michaela - Holubová, Kristína - Valeš, Karel - Buděšínský, Miloš - Vyklický ml., Ladislav - Chodounská, Hana - Kudová, Eva
Physicochemical and biological properties of novel amide-based steroidal inhibitors of NMDA receptors.
Steroids. Roč. 117, Jan (2017), s. 52-61. ISSN 0039-128X. E-ISSN 1878-5867.
[Conference on Isoprenoids /23./. Minsk, 04.09.2016-07.09.2016]
R&D Projects: GA TA ČR(CZ) TE01020028; GA ČR(CZ) GAP303/12/1464; GA MŠMT LO1302; GA MZd(CZ) NV15-29370A; GA ČR(CZ) GBP208/12/G016
Institutional support: RVO:61388963 ; RVO:67985823
Keywords : neurosteroid * NMDA receptor * structure-activity relationship * amide * blood-brain-barrier permeability * Caco-2 assay
OECD category: Organic chemistry; Organic chemistry (FGU-C)
Impact factor: 2.523, year: 2017
Permanent Link: http://hdl.handle.net/11104/0271487