Search results
- 1.0572565 - ÚOCHB 2024 RIV US eng J - Journal Article
Skácel, Jan - Djukic, Stefan - Baszczyňski, Ondřej - Kalčic, Filip - Bílek, Tadeáš - Chalupský, Karel - Kozák, Jaroslav - Dvořáková, Alexandra - Tloušťová, Eva - Kráľová, Zuzana - Šmídková, Markéta - Voldřich, Jan - Rumlová, M. - Pachl, Petr - Brynda, Jiří - Vučková, Tereza - Fábry, Milan - Snášel, Jan - Pichová, Iva - Řezáčová, Pavlína - Mertlíková-Kaiserová, Helena - Janeba, Zlatko
Design, Synthesis, Biological Evaluation, and Crystallographic Study of Novel Purine Nucleoside Phosphorylase Inhibitors.
Journal of Medicinal Chemistry. Roč. 66, č. 10 (2023), s. 6652-6681. ISSN 0022-2623. E-ISSN 1520-4804
R&D Projects: GA TA ČR(CZ) TN01000013; GA MŠMT(CZ) EF16_019/0000729; GA MŠMT LX22NPO5102
Institutional support: RVO:61388963
Keywords : multisubstrate analog inhibitors * transition-state analog * human erythrocytes
OECD category: Organic chemistry
Impact factor: 7.3, year: 2022
Method of publishing: Open access
https://doi.org/10.1021/acs.jmedchem.2c02097
Permanent Link: https://hdl.handle.net/11104/0343213File Download Size Commentary Version Access 10.1021acs.jmedchem.2c02097.pdf 1 5.7 MB Publisher’s postprint open-access - 2.0571248 - ÚOCHB 2024 RIV US eng J - Journal Article
Macháček, Stanislav - Tupec, Michal - Horáček, Natan - Halmová, Martina - Roy, A. - Machara, Aleš - Kyjaková, Pavlína - Lukšan, Ondřej - Pichová, Iva - Hanus, Robert
Evolution of Linoleic Acid Biosynthesis Paved the Way for Ecological Success of Termites.
Molecular Biology and Evolution. Roč. 40, č. 4 (2023), č. článku msad087. ISSN 0737-4038. E-ISSN 1537-1719
R&D Projects: GA ČR(CZ) GA20-17194S
Institutional support: RVO:61388963
Keywords : fatty acyl desaturases * linoleic acid * biosynthesis * termites * Isoptera * Blattodea
OECD category: Biology (theoretical, mathematical, thermal, cryobiology, biological rhythm), Evolutionary biology
Impact factor: 10.7, year: 2022
Method of publishing: Open access
https://doi.org/10.1093/molbev/msad087
Permanent Link: https://hdl.handle.net/11104/0342521 - 3.0568026 - ÚOCHB 2024 RIV CH eng J - Journal Article
Hambalko, J. - Gajdoš, P. - Nicaud, J.-M. - Ledesma-Amaro, R. - Tupec, Michal - Pichová, Iva - Čertík, M.
Biosynthesis of Fatty Acid Derivatives by Recombinant Yarrowia lipolytica Containing MsexD2 and MsexD3 Desaturase Genes from Manduca sexta.
Journal of Fungi. Roč. 9, č. 1 (2023), č. článku 114. E-ISSN 2309-608X
Institutional support: RVO:61388963
Keywords : Yarrowia * pheromone * desaturase * Manduca * conjugase * metabolic engineering
OECD category: Microbiology
Impact factor: 4.7, year: 2022
Method of publishing: Open access
https://doi.org/10.3390/jof9010114
Permanent Link: https://hdl.handle.net/11104/0339363 - 4.0567687 - ÚOCHB 2024 RIV US eng J - Journal Article
Ainelo, A. - Caballero-Montes, J. - Bulvas, Ondřej - Ernits, K. - Wallant, K. C. - Takada, H. - Craig, S. Z. - Mazzucchelli, G. - Zedek, S. - Pichová, Iva - Atkinson, G. C. - Talavera, A. - Martens, C. - Hauryliuk, V. - Garcia-Pino, A.
The structure of DarB in complex with RelNTD reveals nonribosomal activation of Rel stringent factors.
Science Advances. Roč. 9, č. 3 (2023), č. článku eade4077. ISSN 2375-2548. E-ISSN 2375-2548
Institutional support: RVO:61388963
Keywords : di-AMP * ribosome * conservation
OECD category: Microbiology
Impact factor: 13.6, year: 2022
Method of publishing: Open access
https://doi.org/10.1126/sciadv.ade4077
Permanent Link: https://hdl.handle.net/11104/0338915 - 5.0556977 - ÚOCHB 2023 RIV GB eng J - Journal Article
Knejzlík, Zdeněk - Doležal, Michal - Herkommerová, Klára - Clarová, Kamila - Klíma, Martin - Dedola, Matteo - Zborníková, Eva - Rejman, Dominik - Pichová, Iva
The mycobacterial guaB1 gene encodes a guanosine 5 '-monophosphate reductase with a cystathionine-beta-synthase domain.
FEBS Journal. Roč. 289, č. 18 (2022), s. 5571-5598. ISSN 1742-464X. E-ISSN 1742-4658
R&D Projects: GA MŠMT(CZ) EF16_019/0000729
Institutional support: RVO:61388963
Keywords : CBS domain * GMPR * guaB1 * Mycobacterium * purine biosynthesis
OECD category: Biochemistry and molecular biology
Impact factor: 5.4, year: 2022
Method of publishing: Open access
https://doi.org/10.1111/febs.16448
Permanent Link: http://hdl.handle.net/11104/0331102 - 6.0556929 - ÚOCHB 2023 RIV SE eng J - Journal Article
Tupec, Michal - Culka, Martin - Machara, Aleš - Macháček, Stanislav - Bím, Daniel - Svatoš, Aleš - Rulíšek, Lubomír - Pichová, Iva
Understanding desaturation/hydroxylation activity of castor stearoyl Δ9-Desaturase through rational mutagenesis.
Computational and Structural Biotechnology Journal. Roč. 20, March (2022), s. 1378-1388. ISSN 2001-0370. E-ISSN 2001-0370
R&D Projects: GA MŠMT(CZ) LTAUSA19148; GA MŠMT(CZ) LM2015064; GA MŠMT(CZ) EF16_019/0000729
Institutional support: RVO:61388963
Keywords : Δ9 desaturase * methane monooxygenase * reaction mechanism * proton transfer * desaturation * hydroxylation
OECD category: Biochemistry and molecular biology
Impact factor: 6, year: 2022
Method of publishing: Open access
https://doi.org/10.1016/j.csbj.2022.03.010
Permanent Link: http://hdl.handle.net/11104/0331046 - 7.0555722 - ÚOCHB 2023 RIV GB eng J - Journal Article
Zábranská, Helena - Zábranský, Aleš - Lubyová, Barbora - Hodek, Jan - Křenková, Alena - Hubálek, Martin - Weber, Jan - Pichová, Iva
Biogenesis of hepatitis B virus e antigen is driven by translocon-associated protein complex and regulated by conserved cysteine residues within its signal peptide sequence.
FEBS Journal. Roč. 289, č. 10 (2022), s. 2895-2914. ISSN 1742-464X. E-ISSN 1742-4658
R&D Projects: GA MŠMT(CZ) EF16_019/0000729
Institutional support: RVO:61388963
Keywords : HBe * TRAP complex * hepatitis B virus
OECD category: Biochemistry and molecular biology
Impact factor: 5.4, year: 2022
Method of publishing: Open access
https://doi.org/10.1111/febs.16304
Permanent Link: http://hdl.handle.net/11104/0330180 - 8.0542020 - ÚOCHB 2022 RIV GB eng J - Journal Article
Dostál, Jiří - Brynda, Jiří - Vaňková, Lucie - Zia, S. R. - Pichová, Iva - Heidingsfeld, Olga - Lepšík, Martin
Structural determinants for subnanomolar inhibition of the secreted aspartic protease Sapp1p from Candida parapsilosis.
Journal of Enzyme Inhibition and Medicinal Chemistry. Roč. 36, č. 1 (2021), s. 914-921. ISSN 1475-6366. E-ISSN 1475-6374
R&D Projects: GA MŠMT(CZ) EF16_019/0000729
Institutional support: RVO:61388963 ; RVO:86652036
Keywords : inhibitor * crystal structure * peptidomimetics * hydrogen bonds * noncovalent interactions
OECD category: Organic chemistry
Impact factor: 5.756, year: 2021
Method of publishing: Open access
https://doi.org/10.1080/14756366.2021.1906664
Permanent Link: http://hdl.handle.net/11104/0319514 - 9.0541895 - ÚOCHB 2022 RIV US eng J - Journal Article
Wosicki, S. - Kazmierczyk, M. - Gilski, M. - Zábranská, Helena - Pichová, Iva - Jaskolski, M.
Crystal structures of inhibitor complexes of M‐PMV protease with visible flap loops.
Protein Science. Roč. 30, č. 6 (2021), s. 1258-1263. ISSN 0961-8368. E-ISSN 1469-896X
Institutional support: RVO:61388963
Keywords : active site architecture * aspartic protease * dimer * flap structure * inhibitor * Mason‐Pfizer monkey virus * M-PMV * retropepsin * retrovirus
OECD category: Biochemistry and molecular biology
Impact factor: 6.993, year: 2021
Method of publishing: Open access
https://doi.org/10.1002/pro.4072
Permanent Link: http://hdl.handle.net/11104/0319391 - 10.0539494 - ÚOCHB 2022 RIV CH eng J - Journal Article
Snášel, Jan - Machová, Iva - Šolínová, Veronika - Kašička, Václav - Krečmerová, Marcela - Pichová, Iva
Phosphofructokinases a and b from mycobacterium tuberculosis display different catalytic properties and allosteric regulation.
International Journal of Molecular Sciences. Roč. 22, č. 3 (2021), č. článku 1483. E-ISSN 1422-0067
R&D Projects: GA MŠMT(CZ) EF16_019/0000729
Institutional support: RVO:61388963
Keywords : Mycobacterium tuberculosis * glycolysis * phosphofructokinase A and B * allosteric regulation * enzyme kinetics
OECD category: Biochemistry and molecular biology
Impact factor: 6.208, year: 2021
Method of publishing: Open access
https://doi.org/10.3390/ijms22031483
Permanent Link: http://hdl.handle.net/11104/0317591