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- 1.0586165 - ÚOCHB 2025 RIV CZ cze J - Journal Article
Turnovská, Tereza - Jiráček, Jiří - Žáková, Lenka
IGF2: OPOMÍJENÝ HORMON Z RODINY INZULINU S VÝZNAMNÝM TERAPEUTICKÝM POTENCIÁLEM.
[IGF2: A NEGLECTED HORMONE OF THE INSULIN FAMILY WITH SIGNIFICANT THERAPEUTIC POTENTIAL.]
Chemické listy. Roč. 118, č. 6 (2024), s. 321-330. ISSN 0009-2770. E-ISSN 1213-7103
R&D Projects: GA ČR(CZ) GA23-05805S; GA MŠMT(CZ) LX22NPO5104
Institutional support: RVO:61388963
Keywords : IGF2 * insulin * insulin receptor * IGF2 receptor * carcinogenesis * neurodegenerative diseases * embryogenesis
Impact factor: 0.6, year: 2022
Method of publishing: Open access
https://doi.org/10.54779/chl20240321
Permanent Link: https://hdl.handle.net/11104/0353751File Download Size Commentary Version Access 10.54779chl20240321.pdf 0 1.3 MB Publisher’s postprint open-access - 2.0584024 - ÚOCHB 2025 RIV US eng J - Journal Article
Selicharová, Irena - Fabre, Benjamin - Garre Hernández, María Soledad - Lubos, Marta - Pícha, Jan - Voburka, Zdeněk - Mitrová, Katarína - Jiráček, Jiří
Combinatorial libraries of bipodal binders of the insulin receptor.
ChemMedChem. Roč. 19, č. 11 (2024), č. článku e202400145. ISSN 1860-7179. E-ISSN 1860-7187
R&D Projects: GA MŠMT(CZ) LX22NPO5104; GA MŠMT(CZ) EF16_019/0000729
Institutional support: RVO:61388963
Keywords : insulin * receptor * library * scaffold * peptide * combinatorial chemistry
OECD category: Medicinal chemistry
Impact factor: 3.4, year: 2022
Method of publishing: Open access
https://doi.org/10.1002/cmdc.202400145
Permanent Link: https://hdl.handle.net/11104/0352016File Download Size Commentary Version Access 10.1002cmdc.202400145.pdf 0 1.1 MB Publisher’s postprint open-access - 3.0582819 - ÚOCHB 2025 RIV US eng J - Journal Article
Xian, S. - Xiang, Y. - Liu, D. - Fan, B. - Mitrová, Katarína - Ollier, R. C. - Su, B. - Alloosh, M. A. - Jiráček, Jiří - Sturek, M. - Alloosh, M. - Webber, M. J.
Insulin-Dendrimer Nanocomplex for Multi-Day Glucose-Responsive Therapy in Mice and Swine.
Advanced Materials. Roč. 36, č. 5 (2024), č. článku 2308965. ISSN 0935-9648. E-ISSN 1521-4095
R&D Projects: GA MŠMT(CZ) LX22NPO5104
Institutional support: RVO:61388963
Keywords : drug delivery * nanotechnology * materials chemistry * bioconjugation
Impact factor: 29.4, year: 2022
Method of publishing: Limited access
https://doi.org/10.1002/adma.202308965
Permanent Link: https://hdl.handle.net/11104/0350871File Download Size Commentary Version Access 10.1002adma.202308965.pdf 0 4.9 MB Publisher’s postprint require - 4.0581691 - ÚOCHB 2025 RIV NL eng J - Journal Article
Chrudinová, M. - Kirk, N. S. - Chuard, A. - Venugopal, H. - Zhang, F. - Lubos, Marta - Gelfanov, V. - Páníková, Terezie - Žáková, Lenka - Cutone, J. - Mojares, M. - DiMarchi, R. - Jiráček, Jiří - Altindis, E.
A viral insulin-like peptide inhibits IGF-1 receptor phosphorylation and regulates IGF1R gene expression.
Molecular Metabolism. Roč. 80, February (2024), č. článku 101863. ISSN 2212-8778. E-ISSN 2212-8778
R&D Projects: GA MŠMT(CZ) LX22NPO5104
Institutional support: RVO:61388963
Keywords : viral insulin/IGF-1 like peptides (VILPs) * IGF-1 * insulin * IGF1 receptor * IGF1 receptor inhibition * biased signaling * Iridoviridae
OECD category: Biochemistry and molecular biology
Impact factor: 8.1, year: 2022
Method of publishing: Open access
https://doi.org/10.1016/j.molmet.2023.101863
Permanent Link: https://hdl.handle.net/11104/0349880File Download Size Commentary Version Access 10.1016j.molmet.2023.101863.pdf 1 4 MB Publisher’s postprint open-access - 5.0577780 - ÚOCHB 2024 RIV GB eng J - Journal Article
Kertisová, Anna - Žáková, Lenka - Macháčková, Kateřina - Marek, Aleš - Šácha, Pavel - Pompach, Petr - Jiráček, Jiří - Selicharová, Irena
Insulin receptor Arg717 and IGF-1 receptor Arg704 play a key role in ligand binding and in receptor activation.
Open Biology. Roč. 13, č. 11 (2023), č. článku 230142. E-ISSN 2046-2441
R&D Projects: GA MŠMT(CZ) LX22NPO5104; GA MŠMT(CZ) EF16_019/0000729; GA ČR(CZ) GA22-17978S; GA MŠMT(CZ) EF18_046/0015974; GA MŠMT LM2023042
Institutional support: RVO:61388963 ; RVO:86652036
Keywords : mutagenesisin vitro * peptide hormone * eceptor modification * eceptor tyrosine kinase * structure–function
OECD category: Biochemistry and molecular biology
Impact factor: 5.8, year: 2022
Method of publishing: Open access
https://doi.org/10.1098/rsob.230142
Permanent Link: https://hdl.handle.net/11104/0346886File Download Size Commentary Version Access 10.1098rsob.230142.pdf 2 2 MB Publisher’s postprint open-access - 6.0574400 - ÚOCHB 2024 RIV GB eng J - Journal Article
Potalitsyn, Pavlo - Mrázková, Lucie - Selicharová, Irena - Tencerová, Michaela - Ferenčáková, Michaela - Chrudinová, Martina - Turnovská, Tereza - Brzozowski, A. M. - Marek, Aleš - Kaminský, Jakub - Jiráček, Jiří - Žáková, Lenka
Non-glycosylated IGF2 prohormones are more mitogenic than native IGF2.
Communications Biology. Roč. 6, č. 1 (2023), č. článku 863. E-ISSN 2399-3642
R&D Projects: GA ČR(CZ) GA19-14069S; GA MŠMT(CZ) EF16_019/0000729; GA MŠMT(CZ) LX22NPO5104
Institutional support: RVO:61388963 ; RVO:67985823
Keywords : hormone * prohormone * precursor * mitogenic * receptor * IGF
OECD category: Biochemistry and molecular biology
Impact factor: 5.9, year: 2022
Method of publishing: Open access
https://doi.org/10.1038/s42003-023-05239-6
Permanent Link: https://hdl.handle.net/11104/0344735File Download Size Commentary Version Access 10.1038s42003-023-05239-6.pdf 1 2.1 MB Publisher’s postprint open-access - 7.0570637 - ÚOCHB 2024 RIV US eng J - Journal Article
Lin, Jingjing - Asai, Seiya - Selicharová, Irena - Mitrová, Katarína - Kaminský, Jakub - Young, E. - Jiráček, Jiří
Recombinant Insulin-Like Growth Factor 1 Dimers: Receptor Binding Affinities and Activation Abilities.
International Journal of Peptide Research and Therapeutics. Roč. 29, č. 2 (2023), č. článku 33. ISSN 1573-3149. E-ISSN 1573-3904
R&D Projects: GA MŠMT(CZ) LX22NPO5104; GA MŠMT(CZ) EF16_019/0000729
Institutional support: RVO:61388963
Keywords : IGF-1 * receptor * dimer * insulin * binding * phosphorylation * hormone * folding * agonism * antagonism
OECD category: Biochemistry and molecular biology
Impact factor: 2.5, year: 2022
Method of publishing: Open access
https://doi.org/10.1007/s10989-023-10499-1
Permanent Link: https://hdl.handle.net/11104/0341946File Download Size Commentary Version Access 10.1007s10989-023-10499-1.pdf 0 1.2 MB Publisher’s postprint open-access - 8.0567614 - ÚOCHB 2024 RIV GB eng J - Journal Article
Lubos, Marta - Pícha, Jan - Selicharová, Irena - Žák, Jiří - Buděšínský, Miloš - Mitrová, Katarína - Žáková, Lenka - Jiráček, Jiří
Modulation of the antagonistic properties of an insulin mimetic peptide by disulfide bridge modifications.
Journal of Peptide Science. Roč. 29, č. 7 (2023), č. článku e3478. ISSN 1075-2617. E-ISSN 1099-1387
R&D Projects: GA MŠMT(CZ) LX22NPO5104; GA MŠMT(CZ) EF16_019/0000729
Institutional support: RVO:61388963
Keywords : antagonism * dicarba * disulfide mimetics * insulin mimetic peptide * insulin receptor * staple * triazole
OECD category: Biochemistry and molecular biology
Impact factor: 2.1, year: 2022
Method of publishing: Open access
https://doi.org/10.1002/psc.3478
Permanent Link: https://hdl.handle.net/11104/0338851File Download Size Commentary Version Access 10.1002psc.3478.pdf 2 1.1 MB Publisher’s postprint open-access - 9.0566032 - ÚOCHB 2023 RIV GB eng J - Journal Article
Asai, Seiya - Moravcová, J. - Žáková, Lenka - Selicharová, Irena - Hadravová, Romana - Brzozowski, A. M. - Nováček, J. - Jiráček, Jiří
Characterization of insulin crystalline form in isolated β-cell secretory granules.
Open Biology. Roč. 12, č. 12 (2022), č. článku 220322. E-ISSN 2046-2441
R&D Projects: GA MŠMT(CZ) EF16_019/0000729
Research Infrastructure: CIISB II - 90127
Institutional support: RVO:61388963
Keywords : insulin secretory granules * protein crystals * in vivo crystalization * cryo-EM
OECD category: Cell biology
Impact factor: 5.8, year: 2022
Method of publishing: Open access
https://doi.org/10.1098/rsob.220322
Permanent Link: https://hdl.handle.net/11104/0337471 - 10.0564527 - ÚOCHB 2024 RIV GB eng J - Journal Article
Lin, Jingjing - Selicharová, Irena - Mitrová, Katarína - Fabre, Benjamin - Miriyala, Vijay Madhav - Lepšík, Martin - Jiráček, Jiří - Garre Hernández, María Soledad
Targeting the insulin receptor with hormone and peptide dimers.
Journal of Peptide Science. Roč. 29, č. 4 (2023), č. článku e3461. ISSN 1075-2617. E-ISSN 1099-1387
R&D Projects: GA MŠMT(CZ) EF16_019/0000729
Institutional support: RVO:61388963
Keywords : insulin * dimer * bioconjugate * agonism * antagonism * peptidomimetics * receptor * peptide hormone
OECD category: Biochemistry and molecular biology
Impact factor: 2.1, year: 2022
Method of publishing: Limited access
https://doi.org/10.1002/psc.3461
Permanent Link: https://hdl.handle.net/11104/0336187