Search results
- 1.0485179 - ÚOCHB 2018 US eng A - Abstract
Nencka, Radim - Hřebabecký, Hubert - Šála, Michal - Dejmek, Milan - Bouřa, Evžen - Hercík, Kamil - Růžek, D. - Eyer, L.
Inhibitors of Emerging Flaviviruses.
30th International Conference on Antiviral Research (ICAR). Atlanta: ISAR, 2017. s. 120.
[International Conference on Antiviral Research /30./. 21.05.2017-25.05.2017, Atlanta]
Institutional support: RVO:61388963
Keywords : Flavivirus * nucleoside derivatives * nucleotide derivatives * pathogen inhibitor
Subject RIV: CC - Organic Chemistry
Permanent Link: http://hdl.handle.net/11104/0280350 - 2.0481138 - ÚOCHB 2018 CZ eng A - Abstract
Nencka, Radim - Hřebabecký, Hubert - Šála, Michal - Dejmek, Milan - Bouřa, Evžen - Hercík, Kamil - Růžek, D. - Eyer, L.
Nucleoside inhibitors of arthropod-borne flaviviruses.
SCNAC 2017. 17th Symposium on Chemistry of Nucleic Acid Components. Praha: Confis Conference, 2017. s. 79-80.
[SCNAC 2017. Symposium on Chemistry of Nucleic Acid Components /17./. 04.06.2017-09.06.2017, Český Krumlov]
R&D Projects: GA MZd(CZ) NV16-34238A; GA ČR(CZ) GA16-20054S
Institutional support: RVO:61388963
Keywords : flavivirus * nucleoside inhibitors
Subject RIV: CC - Organic Chemistry
Permanent Link: http://hdl.handle.net/11104/0276736 - 3.0470978 - ÚOCHB 2017 FR eng A - Abstract
Hřebabecký, Hubert - Šála, Michal - Dejmek, Milan - Procházková, Eliška - Mackman, R. - Barauskas, O. - Nencka, Radim
Synthesis and biological evaluation of the novel 2', 5'-bridged nucleoside analogs.
22nd International Roundtable on Nucleosides, Nucleotides and Nucleic Acids. Paris: International Society of Nucleosides, Nucleotides and Nucleic Acids, 2016. s. 105.
[International Roundtable on Nucleosides, Nucleotides and Nucleic Acids /22./. 18.07.2016-22.07.2016, Paris]
Institutional support: RVO:61388963
Keywords : nucleoside analogs * antiviral * oligonucleotides
Subject RIV: CC - Organic Chemistry
Permanent Link: http://hdl.handle.net/11104/0268696 - 4.0444280 - ÚOCHB 2016 CZ cze A - Abstract
Procházková, Eliška - Hřebabecký, Hubert - Nencka, Radim - Dračínský, Martin
Konformační analýza a enzymové štěpení fosforamidátového proléčiva konformačně uzamčeného nukleosidu.
[Conformational analysis and enzymatic decomposition of phosphoramidate prodrug of conformationally constrained nucleoside.]
Czech Chemical Society Symposium Series. Roč. 13, č. 1 (2015), s. 34. ISSN 2336-7202.
[Mezioborové setkání mladých biologů, biochemiků a chemiků /15./. 12.05.2015-15.5.2015, Milovy]
R&D Projects: GA ČR GA13-24880S; GA ČR GPP207/12/P625
Institutional support: RVO:61388963
Keywords : NMR spectroscopy * locked nucleosides * enzymatic decomposition
Subject RIV: CC - Organic Chemistry
Permanent Link: http://hdl.handle.net/11104/0246990 - 5.0428283 - ÚOCHB 2015 CZ eng A - Abstract
Procházková, Eliška - Hřebabecký, Hubert - Nencka, Radim - Dračínský, Martin
Conformational analysis and enzymatic decomposition of a locked nucleoside phosphoramidates using NMR spectroscopy.
29th NMR Valtice. Central European NMR Meeting (Theoretical NMR Predictions for Guiding Experiments). Brno: Masaryk University, 2014 - (Novotný, J.; Foroutan-Nejad, C.; Marek, R.). C26. ISBN 978-80-86441-45-0.
[NMR Valtice. Central European NMR Meeting /29./. 27.4.-30.4.2014, Valtice]
R&D Projects: GA ČR GA13-24880S
Institutional support: RVO:61388963
Keywords : enzymatic decomposition * locked nucleosides * conformation * NMR spectroscopy * DFT calculations
Subject RIV: CC - Organic Chemistry
Permanent Link: http://hdl.handle.net/11104/0233664 - 6.0399051 - ÚOCHB 2014 US eng A - Abstract
Dejmek, Milan - Šála, Michal - Hřebabecký, Hubert - Andrei, G. - Balzarini, J. - Naesens, L. - Neyts, J. - Nencka, Radim
Novel norbornane-based nucleoside and nucleotide analogues and their antiviral activities.
26th International Conference on Antiviral Research (ICAR). San Francisco: International Society for Antiviral Research (ISAR), 2013. s. 48-48.
[International Conference on Antiviral Research /26./. 11.05.2013-15.05.2013, San Francisco]
Grant - others:European Social Fund(XE) CZ.1.07/2.2.00/28.0184
Institutional support: RVO:61388963
Keywords : HIV * antiviral activity * norbornane-based derivatives
Subject RIV: CC - Organic Chemistry
Permanent Link: http://hdl.handle.net/11104/0226446 - 7.0389345 - ÚOCHB 2013 US eng A - Abstract
Nencka, Radim - Mertlíková-Kaiserová, Helena - Hřebabecký, Hubert - Šála, Michal - Kögler, Martin - Plačková, Pavla
6-Chloropurines with Anti-Picornavirus Activity Are Selective PI4KIIIbeta Inhibitors.
2nd Antivirals Congress. Cambridge MA: Elsevier, 2012. P.47.
[Antivirals Congress /2./. 11.11.2012-13.11.2012, Cambridge MA]
Institutional research plan: CEZ:AV0Z40550506
Keywords : 6-chloropurines * PI4K * picornaviruses * Coxsackievirus
Subject RIV: CC - Organic Chemistry
Permanent Link: http://hdl.handle.net/11104/0218238 - 8.0384644 - ÚOCHB 2013 CA eng A - Abstract
Dejmek, Milan - Kovačková, Soňa - Zborníková, Eva - Hřebabecký, Hubert - Nencka, Radim
Novel method for the construction of various 2,6,9-trisubstituted purine nucleobases from amine substrates.
20th International Round Table on Nucleosides Nucleotides and Nucleic Acids. Montreal: International Society of Nucleosides, Nucleotides and Nucleic Acids, 2012. s. 32-32.
[International Round Table on Nucleosides Nucleotides and Nucleic Acids /20./. 05.08.2012-09.08.2012, Montreal]
Institutional support: RVO:61388963
Keywords : purine nucleobase * Abacavir
Subject RIV: CC - Organic Chemistry
Permanent Link: http://hdl.handle.net/11104/0214220 - 9.0384605 - ÚOCHB 2013 CA eng A - Abstract
Dejmek, Milan - Hřebabecký, Hubert - Dračínský, Martin - Balzarini, J. - Neyts, J. - Nencka, Radim
New norbornane-based nucleosides locked in South conformation.
20th International Round Table on Nucleosides Nucleotides and Nucleic Acids. Montreal: International Society of Nucleosides, Nucleotides and Nucleic Acids, 2012. s. 8-8.
[International Round Table on Nucleosides Nucleotides and Nucleic Acids /20./. 05.08.2012-09.08.2012, Montreal]
Institutional support: RVO:61388963
Keywords : carbocyclic nucleoside * antiviral activity * cytostatic activity
Subject RIV: CC - Organic Chemistry
Permanent Link: http://hdl.handle.net/11104/0214192 - 10.0369987 - ÚOCHB 2012 GR eng A - Abstract
Dejmek, Milan - Hřebabecký, Hubert - Šála, Michal - Nencka, Radim
Carbocyclic nucleosides with norbornane pseudosugar moiety locked in North conformation.
ESOC 2011. 17th European Symposium on Organic Chemistry. Crete: University of Crete, 2011. P2.121-P2.121.
[ESOC 2011. European Symposium on Organic Chemistry /17./. 10.07.2011-15.07.2011, Crete]
R&D Projects: GA MŠMT 1M0508
Institutional research plan: CEZ:AV0Z40550506
Keywords : norbornane * conformationally locked nucleosides * carbocyclic nucleosides
Subject RIV: CC - Organic Chemistry
Permanent Link: http://hdl.handle.net/11104/0203915