Search results
- 1.0585825 - ÚOCHB 2025 RIV US eng J - Journal Article
Keough, D. T. - Petrová, Magdalena - King, G. - Kratochvil, Michal - Pohl, Radek - Doležalová, E. - Ziková, A. - Guddat, L. W. - Rejman, Dominik
Development of Prolinol Containing Inhibitors of Hypoxanthine-Guanine-Xanthine Phosphoribosyltransferase: Rational Structure-Based Drug Design.
Journal of Medicinal Chemistry. Roč. 67, č. 9 (2024), s. 7158-7175. ISSN 0022-2623. E-ISSN 1520-4804
R&D Projects: GA MŠMT(CZ) LX22NPO5103
Institutional support: RVO:61388963
Keywords : trypanosomiasis * hxgprt * prolinol nucleoside bisphosphonate
OECD category: Organic chemistry
Impact factor: 7.3, year: 2022
Method of publishing: Open access
https://doi.org/10.1021/acs.jmedchem.4c00021
Permanent Link: https://hdl.handle.net/11104/0353500File Download Size Commentary Version Access 10.1021acs.jmedchem.4c00021.pdf 0 12.2 MB Publisher’s postprint open-access - 2.0552686 - ÚOCHB 2023 RIV GB eng J - Journal Article
Lášek, Tomáš - Petrová, Magdalena - Markusová Kóšiová, Ivana - Šimák, Ondřej - Buděšínský, Miloš - Kozák, Jaroslav - Snášel, Jan - Vavřina, Zdeněk - Birkuš, Gabriel - Rosenberg, Ivan - Páv, Ondřej
5′-Phosphonate modified oligoadenylates as potent activators of human RNase L.
Bioorganic & Medicinal Chemistry. Roč. 56, Feb 15 (2022), č. článku 116632. ISSN 0968-0896. E-ISSN 1464-3391
R&D Projects: GA MŠMT(CZ) EF16_019/0000729
Institutional support: RVO:61388963
Keywords : RNase L * Oligoadenylate * Phosphonate oligonucleotide * OAS-RNase L pathway * 2-5A
OECD category: Biochemistry and molecular biology
Impact factor: 3.5, year: 2022
Method of publishing: Limited access
https://doi.org/10.1016/j.bmc.2022.116632
Permanent Link: http://hdl.handle.net/11104/0327809 - 3.0545506 - ÚOCHB 2022 RIV US eng J - Journal Article
Mojr, Viktor - Roghanian, M. - Tamman, H. - Do Pham, Duy Dinh - Petrová, Magdalena - Pohl, Radek - Takada, H. - Van Nerom, K. - Ainelo, H. - Caballero-Montes, J. - Jimmy, S. - Garcia-Pino, A. - Hauryliuk, V. - Rejman, Dominik
Nonhydrolysable Analogues of (p)ppGpp and (p)ppApp Alarmone Nucleotides as Novel Molecular Tools.
ACS Chemical Biology. Roč. 16, č. 9 (2021), s. 1680-1691. ISSN 1554-8929. E-ISSN 1554-8937
R&D Projects: GA MŠMT(CZ) 8F19006
Institutional support: RVO:61388963
Keywords : pppGpp * pppApp * nonhydrolysable * molecular tools
OECD category: Organic chemistry
Impact factor: 4.634, year: 2021
Method of publishing: Limited access
https://doi.org/10.1021/acschembio.1c00398
Permanent Link: http://hdl.handle.net/11104/0322183 - 4.0542802 - BFÚ 2022 RIV GB eng J - Journal Article
Zivkovic, M.L. - Gajarský, M. - Bekova, K. - Stadlbauer, Petr - Vicherek, L. - Petrová, Magdalena - Fiala, R. - Rosenberg, Ivan - Šponer, Jiří - Plavec, J. - Trantírek, L.
Insight into formation propensity of pseudocircular DNA G-hairpins.
Nucleic Acids Research. Roč. 49, č. 4 (2021), s. 2317-2332. ISSN 0305-1048. E-ISSN 1362-4962
R&D Projects: GA ČR(CZ) GA17-12703S; GA MŠMT EF15_003/0000477
Institutional support: RVO:68081707 ; RVO:61388963
Keywords : molecular-dynamics simulations * g-quadruplex structure * amber force-field * g-triplex * folding pathways
OECD category: Biochemistry and molecular biology; Biochemistry and molecular biology (UOCHB-X)
Impact factor: 19.160, year: 2021
Method of publishing: Open access
https://academic.oup.com/nar/article/49/4/2317/6125665
Permanent Link: http://hdl.handle.net/11104/0320148 - 5.0475163 - ÚOCHB 2018 RIV GB eng J - Journal Article
Páv, Ondřej - Barvík, I. - Liboska, Radek - Petrová, Magdalena - Šimák, Ondřej - Rosenbergová, Šárka - Novák, Pavel - Buděšínský, Miloš - Rosenberg, Ivan
Tuning the hybridization properties of modified oligonucleotides: from flexible to conformationally constrained phosphonate internucleotide linkages.
Organic & Biomolecular Chemistry. Roč. 15, č. 3 (2017), s. 701-707. ISSN 1477-0520. E-ISSN 1477-0539
R&D Projects: GA ČR GA13-26526S; GA MZd NV15-31604A
Institutional support: RVO:61388963
Keywords : molecular dynamics simulations * sugar phosphate backbone * nucleic acid recognition
OECD category: Organic chemistry
Impact factor: 3.423, year: 2017
Permanent Link: http://hdl.handle.net/11104/0272011 - 6.0461797 - ÚOCHB 2017 RIV US eng J - Journal Article
Kostov, Ondřej - Páv, Ondřej - Buděšínský, Miloš - Liboska, Radek - Šimák, Ondřej - Petrová, Magdalena - Novák, Pavel - Rosenberg, Ivan
4-Toluenesulfonyloxymethyl-(H)-phosphinate: A Reagent for the Introduction of O- and S-Methyl-(H)-phosphinate Moieties.
Organic Letters. Roč. 18, č. 11 (2016), s. 2704-2707. ISSN 1523-7060. E-ISSN 1523-7052
R&D Projects: GA ČR GA13-26526S; GA MZd NV15-31604A; GA TA ČR TA03010598; GA MŠMT(CZ) LO1304
Institutional support: RVO:61388963
Keywords : acyclic nucleoside phosphonates * phosphinyl dipeptide isosteres * efficient synthesis
Subject RIV: CC - Organic Chemistry
Impact factor: 6.579, year: 2016
Permanent Link: http://hdl.handle.net/11104/0261379 - 7.0446565 - ÚOCHB 2016 RIV US eng J - Journal Article
Petrová, Magdalena - Páv, Ondřej - Buděšínský, Miloš - Zborníková, Eva - Novák, Pavel - Rosenbergová, Šárka - Pačes, Ondřej - Liboska, Radek - Dvořáková, Ivana - Šimák, Ondřej - Rosenberg, Ivan
Straightforward Synthesis of Purine 4 '-Alkoxy-2 '-deoxynucleosides: First Report of Mixed Purine-Pyrimidine 4 '-Alkoxyoligodeoxynucleotides as New RNA Mimics.
Organic Letters. Roč. 17, č. 14 (2015), s. 3426-3429. ISSN 1523-7060. E-ISSN 1523-7052
R&D Projects: GA ČR GA13-26526S; GA ČR GA13-24880S; GA TA ČR TA03010598
Institutional support: RVO:61388963
Keywords : 4'-alkoxyoligodeoxynucleotides * RNA mimics * antisense
Subject RIV: CC - Organic Chemistry
Impact factor: 6.732, year: 2015
Permanent Link: http://hdl.handle.net/11104/0248620 - 8.0435239 - ÚOCHB 2015 RIV GB eng J - Journal Article
Šimák, Ondřej - Pachl, Petr - Fábry, Milan - Buděšínský, Miloš - Jandušík, T. - Hnízda, Aleš - Skleničková, Radka - Petrová, Magdalena - Veverka, Václav - Řezáčová, Pavlína - Brynda, Jiří - Rosenberg, Ivan
Conformationally constrained nucleoside phosphonic acids - potent inhibitors of human mitochondrial and cytosolic 5'(3')-nucleotidases.
Organic & Biomolecular Chemistry. Roč. 12, č. 40 (2014), s. 7971-7982. ISSN 1477-0520. E-ISSN 1477-0539
R&D Projects: GA ČR GA203/09/0820; GA ČR GA13-24880S; GA ČR GA13-26526S; GA MŠMT(CZ) LK11205; GA AV ČR KAN200520801
Institutional support: RVO:61388963 ; RVO:68378050
Keywords : 5'(3')-nucleotidase * structure * inhibition * cdN * mdN * nucleoside * SAR * phosphonic acid
Subject RIV: CC - Organic Chemistry
Impact factor: 3.562, year: 2014
Permanent Link: http://hdl.handle.net/11104/0239546 - 9.0428628 - ÚOCHB 2015 RIV FR eng J - Journal Article
Markusová Kóšiová, Ivana - Šimák, Ondřej - Panova, Natalya - Buděšínský, Miloš - Petrová, Magdalena - Rejman, Dominik - Liboska, Radek - Páv, Ondřej - Rosenberg, Ivan
Inhibition of human thymidine phosphorylase by conformationally constrained pyrimidine nucleoside phosphonic acids and their "open-structure" isosteres.
European Journal of Medicinal Chemistry. Roč. 74, Mar 3 (2014), s. 145-168. ISSN 0223-5234. E-ISSN 1768-3254
R&D Projects: GA ČR GA203/09/0820; GA ČR GA202/09/0193; GA ČR GA13-24880S; GA ČR GA13-26526S
Institutional support: RVO:61388963
Keywords : phosphonate * conformationally constrained nucleotide analog * human thymidine phosphorylase * PBMC * bi-substrate-like inhibitor * Michael addition
Subject RIV: CC - Organic Chemistry
Impact factor: 3.447, year: 2014
Permanent Link: http://hdl.handle.net/11104/0233950 - 10.0428075 - ÚFE 2015 RIV GB eng J - Journal Article
Šípová, Hana - Špringer, Tomáš - Rejman, Dominik - Šimák, Ondřej - Petrová, Magdalena - Novák, Pavel - Rosenbergová, Šárka - Páv, Ondřej - Liboska, Radek - Barvík, I. - Štěpánek, J. - Rosenberg, Ivan - Homola, Jiří
5´-O-Methylphosphonate nucleic acids—new modified DNAs that increase the Escherichia coli RNase H cleavage rate of hybrid duplexes.
Nucleic Acids Research. Roč. 42, č. 8 (2014), s. 5378-5389. ISSN 0305-1048. E-ISSN 1362-4962
R&D Projects: GA ČR GA203/09/0820; GA ČR GA13-26526S
Institutional support: RVO:67985882 ; RVO:61388963
Keywords : Antisense Oligonucleotides * Ribonuclease H * Surface Plasmon Resonance
Subject RIV: JA - Electronics ; Optoelectronics, Electrical Engineering; CC - Organic Chemistry (UOCHB-X)
Impact factor: 9.112, year: 2014
Permanent Link: http://hdl.handle.net/11104/0233466File Download Size Commentary Version Access UFE 0428075.pdf 7 6 MB Publisher’s postprint require