Search results
- 1.0489708 - ÚOCHB 2019 RIV US eng J - Journal Article
Macháčková, Kateřina - Chrudinová, Martina - Radosavljević, Jelena - Potalitsyn, Pavlo - Křížková, Květoslava - Fábry, Milan - Selicharová, Irena - Collinsová, Michaela - Brzozowski, A. M. - Žáková, Lenka - Jiráček, Jiří
Converting Insulin-like Growth Factors 1 and 2 into High-Affinity Ligands for Insulin Receptor Isoform A by the Introduction of an Evolutionarily Divergent Mutation.
Biochemistry. Roč. 57, č. 16 (2018), s. 2373-2382. ISSN 0006-2960
R&D Projects: GA ČR GA15-19018S
Institutional support: RVO:61388963 ; RVO:68378050
Keywords : insulin-like growth factor * insulin * receptor * analog
OECD category: Biochemistry and molecular biology
Impact factor: 2.952, year: 2018
https://pubs.acs.org/doi/10.1021/acs.biochem.7b01260
Permanent Link: http://hdl.handle.net/11104/0284074File Download Size Commentary Version Access 0489708.pdf 5 3.3 MB Publisher’s postprint open-access - 2.0484559 - ÚOCHB 2018 RIV US eng J - Journal Article
Macháčková, Kateřina - Collinsová, Michaela - Chrudinová, Martina - Selicharová, Irena - Pícha, Jan - Buděšínský, Miloš - Vaněk, Václav - Žáková, Lenka - Brzozowski, A. M. - Jiráček, Jiří
Insulin-like Growth Factor 1 Analogs Clicked in the C Domain: Chemical Synthesis and Biological Activities.
Journal of Medicinal Chemistry. Roč. 60, č. 24 (2017), s. 10105-10117. ISSN 0022-2623. E-ISSN 1520-4804
Institutional support: RVO:61388963
Keywords : IGF-1 * receptor * synthesis * triazole
OECD category: Biochemistry and molecular biology
Impact factor: 6.253, year: 2017
http://pubs.acs.org/doi/full/10.1021/acs.jmedchem.7b01331
Permanent Link: http://hdl.handle.net/11104/0279723File Download Size Commentary Version Access 0484559.pdf 6 1.7 MB Publisher’s postprint open-access - 3.0475234 - ÚOCHB 2018 RIV GB eng J - Journal Article
Pícha, Jan - Buděšínský, Miloš - Macháčková, Kateřina - Collinsová, Michaela - Jiráček, Jiří
Optimized syntheses of Fmoc azido amino acids for the preparation of azidopeptides.
Journal of Peptide Science. Roč. 23, č. 3 (2017), s. 202-214. ISSN 1075-2617. E-ISSN 1099-1387
R&D Projects: GA ČR GA14-17305S
Institutional support: RVO:61388963
Keywords : azides * azidopeptides * synthesis
OECD category: Biochemistry and molecular biology
Impact factor: 1.969, year: 2017
http://onlinelibrary.wiley.com/doi/10.1002/psc.2968/full
Permanent Link: http://hdl.handle.net/11104/0272076 - 4.0469437 - ÚOCHB 2017 RIV US eng J - Journal Article
Fabre, Benjamin - Pícha, Jan - Vaněk, Václav - Selicharová, Irena - Chrudinová, Martina - Collinsová, Michaela - Žáková, Lenka - Buděšínský, Miloš - Jiráček, Jiří
Synthesis and Evaluation of a Library of Trifunctional Scaffold-Derived Compounds as Modulators of the Insulin Receptor.
ACS Combinatorial Science. Roč. 18, č. 12 (2016), s. 710-722. ISSN 2156-8952. E-ISSN 2156-8944
R&D Projects: GA ČR GA14-17305S
Institutional support: RVO:61388963
Keywords : insulin mimetics * insulin receptor * library * protein-protein interactions * scaffold * trifunctional
Subject RIV: CE - Biochemistry
Impact factor: 3.168, year: 2016
http://pubs.acs.org/doi/full/10.1021/acscombsci.6b00132
Permanent Link: http://hdl.handle.net/11104/0267220 - 5.0466450 - ÚOCHB 2017 RIV US eng J - Journal Article
Hexnerová, Rozálie - Křížková, Květoslava - Fábry, Milan - Sieglová, Irena - Kedrová, Kateřina - Collinsová, Michaela - Ullrichová, P. - Srb, Pavel - Williams, C. - Crump, M. P. - Tošner, Z. - Jiráček, Jiří - Veverka, Václav - Žáková, Lenka
Probing Receptor Specificity by Sampling the Conformational Space of the Insulin-like Growth Factor II C-domain.
Journal of Biological Chemistry. Roč. 291, č. 40 (2016), s. 21234-21245. ISSN 0021-9258. E-ISSN 1083-351X
R&D Projects: GA ČR GA15-19018S; GA MŠMT(CZ) LK11205; GA MŠMT(CZ) LO1304
Institutional support: RVO:61388963 ; RVO:68378050
Keywords : insulin * IGF-2 * receptor
Subject RIV: CE - Biochemistry
Impact factor: 4.125, year: 2016
http://www.jbc.org/content/291/40/21234.full
Permanent Link: http://hdl.handle.net/11104/0264739File Download Size Commentary Version Access 0466450.pdf 0 1.9 MB Publisher’s postprint open-access - 6.0461800 - ÚOCHB 2017 RIV US eng J - Journal Article
Křížková, Květoslava - Chrudinová, Martina - Povalová, Anna - Selicharová, Irena - Collinsová, Michaela - Vaněk, Václav - Brzozowski, A. M. - Jiráček, Jiří - Žáková, Lenka
Insulin-Insulin-like Growth Factors Hybrids as Molecular Probes of Hormone:Receptor Binding Specificity.
Biochemistry. Roč. 55, č. 21 (2016), s. 2903-2913. ISSN 0006-2960
R&D Projects: GA ČR GA15-19018S
Institutional support: RVO:61388963
Keywords : alanine scanning mutagenesis * high-affinity binding * type 1 IGF receptor
Subject RIV: CE - Biochemistry
Impact factor: 2.938, year: 2016
http://pubs.acs.org/doi/pdf/10.1021/acs.biochem.6b00140
Permanent Link: http://hdl.handle.net/11104/0261380File Download Size Commentary Version Access 0461800.pdf 2 1.9 MB Publisher’s postprint open-access - 7.0458657 - ÚOCHB 2017 RIV GB eng J - Journal Article
Viková, Jitka - Collinsová, Michaela - Kletvíková, Emília - Buděšínský, Miloš - Kaplan, V. - Žáková, Lenka - Veverka, Václav - Hexnerová, Rozálie - Tarazona Avinó, R. J. - Straková, Jana - Selicharová, Irena - Vaněk, Václav - Wright, D. W. - Watson, C. J. - Turkenburg, J. P. - Brzozowski, A. M. - Jiráček, Jiří
Rational steering of insulin binding specificity by intra-chain chemical crosslinking.
Scientific Reports. Roč. 6, Jan 21 (2016), č. článku 19431. ISSN 2045-2322. E-ISSN 2045-2322
R&D Projects: GA MŠMT(CZ) LK11205; GA MŠMT(CZ) LO1304
Institutional support: RVO:61388963
Keywords : insulin * insulin receptor * diabetes * protein design * protein synthesis
Subject RIV: CE - Biochemistry
Impact factor: 4.259, year: 2016
http://www.nature.com/articles/srep19431
Permanent Link: http://hdl.handle.net/11104/0258905File Download Size Commentary Version Access 0458657.pdf 5 2.4 MB Publisher’s postprint open-access - 8.0435229 - ÚOCHB 2015 RIV US eng J - Journal Article
Žáková, Lenka - Kletvíková, Emília - Lepšík, Martin - Collinsová, Michaela - Watson, C. J. - Turkenburg, J. P. - Jiráček, Jiří - Brzozowski, A. M.
Human insulin analogues modified at the B26 site reveal a hormone conformation that is undetected in the receptor complex.
Acta Crystallographica Section D-Biological Crystallography. Roč. 70, č. 10 (2014), s. 2765-2774. ISSN 0907-4449
R&D Projects: GA ČR GPP207/11/P430; GA ČR GBP208/12/G016
Institutional support: RVO:61388963
Keywords : insulin * insulin receptor * complex * active form * analog * structure
Subject RIV: CE - Biochemistry
Impact factor: 7.232, year: 2013
Permanent Link: http://hdl.handle.net/11104/0239539 - 9.0429661 - ÚOCHB 2015 RIV US eng J - Journal Article
Kosinová, Lucie - Veverka, Václav - Novotná, P. - Collinsová, Michaela - Urbanová, M. - Moody, N. R. - Turkenburg, J. P. - Jiráček, Jiří - Brzozowski, A. M. - Žáková, Lenka
Insight into the Structural and Biological Relevance of the T/R Transition of the N-Terminus of the B-Chain in Human Insulin.
Biochemistry. Roč. 53, č. 21 (2014), s. 3392-3402. ISSN 0006-2960
R&D Projects: GA ČR GPP207/11/P430; GA ČR GAP208/11/0105; GA MŠMT(CZ) LK11205
Institutional support: RVO:61388963
Keywords : insulin * structure * N-terminus * B-chain * T/R transition
Subject RIV: CE - Biochemistry
Impact factor: 3.015, year: 2014
Permanent Link: http://hdl.handle.net/11104/0234773 - 10.0194766 - UOCHB-X 20030071 RIV DE eng J - Journal Article
Koval, Dušan - Kašička, Václav - Jiráček, Jiří - Collinsová, Michaela
Separation of diastereomers of phosphinic pseudopeptides by capillary zone electrophoresis and reverse phase high-performance liquid chromatography.
Journal of Separation Science. Roč. 26, - (2003), s. 653-660. ISSN 1615-9306. E-ISSN 1615-9314
R&D Projects: GA ČR GA203/02/1467; GA AV ČR IAB4055003
Institutional research plan: CEZ:AV0Z4055905
Keywords : phosphinate * phosphinic pseudopeptides * capillary zone electrophoresis
Subject RIV: CE - Biochemistry
Impact factor: 2.108, year: 2003
Permanent Link: http://hdl.handle.net/11104/0090437