Search results
- 1.0556294 - ÚMG 2022 RIV CH eng J - Journal Article
Reiberger, R. - Radilova, K. - Král, M. - Zima, V. - Majer, P. - Brynda, Jiří - Dračínský, M. - Konvalinka, J. - Kožíšek, M. - Machara, A.
Synthesis and In Vitro Evaluation of C-7 and C-8 Luteolin Derivatives as Influenza Endonuclease Inhibitors.
International Journal of Molecular Sciences. Roč. 22, č. 14 (2021), č. článku 7735. E-ISSN 1422-0067
Institutional support: RVO:68378050
Keywords : bio-isosterism * cross-coupling * endonuclease inhibitor * flavonoids * influenza * Mannich reaction * RNA polymerase
OECD category: Biochemistry and molecular biology
Impact factor: 6.208, year: 2021
Method of publishing: Open access
https://www.mdpi.com/1422-0067/22/14/7735
Permanent Link: http://hdl.handle.net/11104/0330581 - 2.0544834 - ÚMG 2022 RIV US eng J - Journal Article
Kryštůfek, R. - Šácha, P. - Starková, J. - Brynda, Jiří - Hradilek, M. - Tloušťová, E. - Grzymska, J. - Rut, W. - Boucher, M. J. - Drag, M. - Majer, P. - Hájek, M. - Řezáčová, Pavlína - Madhani, H. D. - Craik, C. S. - Konvalinka, J.
Re-emerging Aspartic Protease Targets: Examining Cryptococcus neoformans Major Aspartyl Peptidase 1 as a Target for Antifungal Drug Discovery.
Journal of Medicinal Chemistry. Roč. 64, č. 10 (2021), s. 6706-6719. ISSN 0022-2623. E-ISSN 1520-4804
Institutional support: RVO:68378050
Keywords : immunodeficiency-virus hiv * in-vitro * virulence factors * type-1 protease * inhibitors * pepsin * specificity * meningitis * expression * strategies
OECD category: Biochemistry and molecular biology
Impact factor: 8.039, year: 2021
Method of publishing: Open access
https://pubs.acs.org/doi/10.1021/acs.jmedchem.0c02177
Permanent Link: http://hdl.handle.net/11104/0321646 - 3.0544819 - ÚMG 2022 RIV NL eng J - Journal Article
Hejdanek, J. - Radilova, K. - Pachl, P. - Hodek, J. - Machara, A. - Weber, J. - Řezáčová, Pavlína - Konvalinka, J. - Kožíšek, M.
structural characterization of the interaction between the C-terminal domain of the influenza polymerase PA subunit and an optimized small peptide inhibitor.
Antiviral Research. Roč. 185, January (2021), č. článku 104971. ISSN 0166-3542. E-ISSN 1872-9096
Institutional support: RVO:68378050
Keywords : Antiviral peptides * Influenza a polymerase * Protein-protein interaction * AlphaScreen
OECD category: Pharmacology and pharmacy
Impact factor: 10.103, year: 2021
Method of publishing: Limited access
https://www.sciencedirect.com/science/article/pii/S0166354220303855?via%3Dihub
Permanent Link: http://hdl.handle.net/11104/0321625 - 4.0540277 - ÚMG 2021 RIV US eng J - Journal Article
Tykvart, J. - Navrátil, V. - Kugler, Michael - Šácha, P. - Schimer, J. - Hlaváčková, A. - Tenora, L. - Zemanová, J. - Dejmek, M. - Král, Vlastimil - Potáček, M. - Majer, P. - Jahn, U. - Brynda, Jiří - Řezáčová, Pavlína - Konvalinka, J.
Identification of Novel Carbonic Anhydrase IX Inhibitors Using High-Throughput Screening of Pooled Compound Libraries by DNA-Linked Inhibitor Antibody Assay (DIANA).
SLAS Discovery. Roč. 25, č. 9 (2020), s. 1026-1037. ISSN 2472-5552. E-ISSN 2472-5560
Institutional support: RVO:68378050
Keywords : high-throughput screening * carbonic anhydrase IX * drug discovery * DNA-linked inhibitor antibody assay
OECD category: Biochemistry and molecular biology
Impact factor: 2.918, year: 2020
Method of publishing: Limited access
https://journals.sagepub.com/doi/10.1177/2472555220918836
Permanent Link: http://hdl.handle.net/11104/0317971 - 5.0539161 - ÚMG 2021 RIV FR eng J - Journal Article
Zima, V. - Radilova, K. - Kožíšek, M. - Albinana, C. B. - Karlukova, E. - Brynda, Jiří - Fanfrlik, J. - Flieger, M. - Hodek, J. - Weber, J. - Majer, P. - Konvalinka, J. - Machara, A.
Unraveling the anti-influenza effect of flavonoids: Experimental validation of luteolin and its congeners as potent influenza endonuclease inhibitors.
European Journal of Medicinal Chemistry. Roč. 208, December (2020), č. článku 112754. ISSN 0223-5234. E-ISSN 1768-3254
Institutional support: RVO:68378050
Keywords : Influenza * Neuraminidase * Polyphenols * PA(N) endonuclease Inhibitors * RNA polymerase
OECD category: Biochemistry and molecular biology
Impact factor: 6.514, year: 2020
Method of publishing: Open access
https://www.sciencedirect.com/science/article/pii/S0223523420307261?via%3Dihub
Permanent Link: http://hdl.handle.net/11104/0316866 - 6.0531481 - ÚACH 2021 RIV NL eng J - Journal Article
Zatloukalová, J. - Dewynter-Marty, V. - Zatloukal, J. - Kolář, K. - Bernachy-Barbe, F. - Bezdička, Petr - Konvalinka, J.
Microstructural and micro-mechanical property changes of cement pastes for ILW immobilization due to irradiation.
Journal of Nuclear Materials. Roč. 540, NOV (2020), č. článku 152346. ISSN 0022-3115. E-ISSN 1873-4820
Institutional support: RVO:61388980
Keywords : gamma irradiation * microstructure * concrete
OECD category: Inorganic and nuclear chemistry
Impact factor: 2.936, year: 2020
Method of publishing: Limited access
https://doi.org/10.1016/j.jnucmat.2020.152346
Permanent Link: http://hdl.handle.net/11104/0310141File Download Size Commentary Version Access Microstructural.pdf 0 2.4 MB CC BY-NC-ND licence Author’s postprint open-access - 7.0523062 - ÚMG 2020 RIV US eng J - Journal Article
Pospíšilová, K. - Knedlik, T. - Šácha, P. - Kostka, L. - Schimer, J. - Brynda, Jiří - Král, Vlastimil - Cigler, P. - Navrátil, V. - Etrych, T. - Šubr, V. - Kugler, Michael - Fábry, Milan - Řezáčová, Pavlína - Konvalinka, J.
Inhibitor-Polymer Conjugates as a Versatile Tool for Detection and Visualization of Cancer-Associated Carbonic Anhydrase Isoforms.
ACS Omega. Roč. 4, č. 4 (2019), s. 6746-6756. ISSN 2470-1343. E-ISSN 2470-1343
Institutional support: RVO:68378050
Keywords : renal-cell carcinoma * molecule-drug conjugate * intrinsic marker * mn/ca ix * ca-ix * expression * hypoxia * antibody * prognosis * tumors
OECD category: Polymer science
Impact factor: 2.870, year: 2019
Method of publishing: Open access
https://pubs.acs.org/doi/10.1021/acsomega.9b00596
Permanent Link: http://hdl.handle.net/11104/0307469 - 8.0522874 - ÚMG 2020 RIV GB eng J - Journal Article
Zima, V. - Albinana, C. B. - Rojíková, K. - Pokorná, J. - Pachl, P. - Řezáčová, Pavlína - Hudlický, J. - Navrátil, V. - Majer, P. - Konvalinka, J. - Kožíšek, M. - Machara, A.
Investigation of flexibility of neuraminidase 150-loop using tamiflu derivatives in influenza A viruses H1N1 and H5N1.
Bioorganic & Medicinal Chemistry. Roč. 27, č. 13 (2019), s. 2935-2947. ISSN 0968-0896. E-ISSN 1464-3391
Institutional support: RVO:68378050
Keywords : Influenza neuraminidase * Oseltamivir * Click chemistry * Crystal structure
OECD category: Cell biology
Impact factor: 3.073, year: 2019
Method of publishing: Limited access
https://www.sciencedirect.com/science/article/pii/S0968089619305358?via%3Dihub
Permanent Link: http://hdl.handle.net/11104/0307288 - 9.0505253 - ÚMG 2020 RIV GB eng J - Journal Article
Srb, P. - Svoboda, M. - Benda, L. - Lepšík, M. - Tarabek, J. - Šícha, V. - Gruener, B. - Grantz-Saskova, K. - Brynda, Jiří - Řezáčová, Pavlína - Konvalinka, J. - Veverka, V.
Capturing a dynamically interacting inhibitor by paramagnetic NMR spectroscopy.
Physical Chemistry Chemical Physics. Roč. 21, č. 10 (2019), s. 5661-5673. ISSN 1463-9076. E-ISSN 1463-9084
R&D Projects: GA ČR(CZ) GA15-05677S
Institutional support: RVO:68378050
Keywords : hiv-1 protease * pseudocontact shifts * proteins * assignment * exchange * restraints * complexes * molecule
OECD category: Biophysics
Impact factor: 3.430, year: 2019
Method of publishing: Limited access
https://pubs.rsc.org/en/content/articlelanding/2019/CP/C9CP00416E#!divAbstract
Permanent Link: http://hdl.handle.net/11104/0297062 - 10.0503521 - ÚMG 2019 RIV GB eng J - Journal Article
Kožíšek, M. - Navrátil, V. - Rojíková, K. - Pokorná, J. - Albinana, C. B. - Pachl, P. - Zemanová, J. - Machara, A. - Šácha, P. - Hudlický, J. - Císařová, I. - Řezáčová, Pavlína - Konvalinka, J.
DNA-linked inhibitor antibody assay (DIANA) as a new method for screening influenza neuraminidase inhibitors.
Biochemical Journal. Roč. 475, č. 23 (2018), s. 3847-3860. ISSN 0264-6021. E-ISSN 1470-8728
Institutional support: RVO:68378050
Keywords : DNA-linked inhibitor antibody assay (DIANA) * influenza neuraminidase * inhibition constant
OECD category: Biochemistry and molecular biology
Impact factor: 4.331, year: 2018
Permanent Link: http://hdl.handle.net/11104/0295338