Search results
- 1.0574512 - BFÚ 2024 RIV US eng J - Journal Article
Malina, Jaroslav - Kostrhunová, Hana - Scott, P. - Brabec, Viktor
Metallohelices stabilize DNA three-way junctions and induce DNA damage in cancer cells.
Nucleic Acids Research. Roč. 51, č. 14 (2023), s. 7174-7183. ISSN 0305-1048. E-ISSN 1362-4962
R&D Projects: GA ČR(CZ) GA21-27514S
Institutional support: RVO:68081707
Keywords : RECOGNITION
OECD category: Biochemistry and molecular biology
Impact factor: 14.9, year: 2022
Method of publishing: Open access
https://academic.oup.com/nar/article/51/14/7174/7205766?login=true
Permanent Link: https://hdl.handle.net/11104/0350041 - 2.0571528 - BFÚ 2024 RIV GB eng J - Journal Article
Malina, Jaroslav - Kostrhunová, Hana - Song, H. - Scott, P. - Brabec, Viktor
Asymmetric triplex metallohelices stabilise DNA G-quadruplexes in promoter oncogene sequences and efficiently reduce their expression in cancer cells.
Journal of Enzyme Inhibition and Medicinal Chemistry. Roč. 38, č. 1 (2023), č. článku 2198678. ISSN 1475-6366. E-ISSN 1475-6374
R&D Projects: GA ČR(CZ) GA21-27514S
Institutional support: RVO:68081707
Keywords : Metallohelices * G-quadruplexes * telomeres * expression of oncogenes * DNA synthesis
OECD category: Biochemistry and molecular biology
Impact factor: 5.6, year: 2022
Method of publishing: Open access
https://www.tandfonline.com/doi/full/10.1080/14756366.2023.2198678
Permanent Link: https://hdl.handle.net/11104/0345688 - 3.0563243 - BFÚ 2023 RIV GB eng J - Journal Article
Malina, Jaroslav - Kostrhunová, Hana - Brabec, Viktor
Dinuclear nickel(ii) supramolecular helicates down-regulate gene expression in human cells by stabilizing DNA G-quadruplexes formed in the promoter regions.
Inorganic Chemistry Frontiers. Roč. 9, č. 21 (2022), s. 5597-5606. ISSN 2052-1553. E-ISSN 2052-1553
R&D Projects: GA ČR(CZ) GA20-00735S
Institutional support: RVO:68081707
Keywords : METALLOSUPRAMOLECULAR CYLINDERS * C-MYC * BINDING
OECD category: Organic chemistry
Impact factor: 7, year: 2022
Method of publishing: Limited access
https://pubs.rsc.org/en/content/articlelanding/2022/QI/D2QI01435A
Permanent Link: https://hdl.handle.net/11104/0340612 - 4.0555923 - BFÚ 2023 RIV GB eng J - Journal Article
Malina, Jaroslav - Kostrhunová, Hana - Novohradský, Vojtěch - Scott, P. - Brabec, Viktor
Metallohelix vectors for efficient gene delivery via cationic DNA nanoparticles.
Nucleic Acids Research. Roč. 50, č. 2 (2022), s. 674-683. ISSN 0305-1048. E-ISSN 1362-4962
R&D Projects: GA ČR(CZ) GA20-00735S
Institutional support: RVO:68081707
Keywords : ruthenium(ii) complexes * nonviral vectors * viral vectors * condensation * therapy
OECD category: Biochemistry and molecular biology
Impact factor: 14.9, year: 2022
Method of publishing: Open access
https://academic.oup.com/nar/article/50/2/674/6501240?login=true
Permanent Link: https://hdl.handle.net/11104/0340259 - 5.0555580 - BFÚ 2022 RIV DE eng J - Journal Article
de Paiva, R. E. F. - Peterson, E. J. - Malina, Jaroslav - Zoepfl, M. - Hampton, J. D. - Johnson, W. E. - Graminha, A. - Ourahmane, A. - McVoy, M. A. - Brabec, Viktor - Berners-Price, S.J. - Farrell, N.
On the Biology of Werner's Complex.
Angewandte Chemie - International Edition. Roč. 60, č. 31 (2021), s. 17123-17130. ISSN 1433-7851. E-ISSN 1521-3773
R&D Projects: GA ČR(CZ) GC20-14082J
Institutional support: RVO:68081707
Keywords : heparan-sulfate * platinum complexes * cell-surface * dna-binding * entry * recognition * inhibition * chemistry
OECD category: Organic chemistry
Impact factor: 16.823, year: 2021
Method of publishing: Limited access
https://onlinelibrary.wiley.com/doi/10.1002/anie.202105019
Permanent Link: http://hdl.handle.net/11104/0330042 - 6.0554901 - BFÚ 2022 RIV GB eng J - Journal Article
Malina, Jaroslav - Kostrhunová, Hana - Farrell, N. - Brabec, Viktor
Antitumor substitution-inert polynuclear platinum complexes stabilize G-quadruplex DNA and suppress G-quadruplex-mediated gene expression.
Inorganic Chemistry Frontiers. Roč. 8, č. 13 (2021), s. 3371-3381. ISSN 2052-1553. E-ISSN 2052-1553
R&D Projects: GA ČR(CZ) GC20-14082J
Institutional support: RVO:68081707
Keywords : myc g-quadruplex * promoter region * phosphate clamp * metal-complexes * nucleic-acids
OECD category: Organic chemistry
Impact factor: 7.779, year: 2021
Method of publishing: Limited access
https://pubs.rsc.org/en/content/articlelanding/2021/QI/D1QI00488C
Permanent Link: http://hdl.handle.net/11104/0329516 - 7.0553650 - BFÚ 2022 RIV DE eng J - Journal Article
Malina, Jaroslav - Kostrhunová, Hana - Scott, P. - Brabec, Viktor
Fe-II Metallohelices Stabilize DNA G-Quadruplexes and Downregulate the Expression of G-Quadruplex-Regulated Oncogenes.
Chemistry - A European Journal. Roč. 27, č. 45 (2021), s. 11682-11692. ISSN 0947-6539. E-ISSN 1521-3765
R&D Projects: GA ČR(CZ) GA20-00735S
Institutional support: RVO:68081707
Keywords : displacement assay * promoter region * myc
OECD category: Organic chemistry
Impact factor: 5.020, year: 2021
Method of publishing: Limited access
https://chemistry-europe.onlinelibrary.wiley.com/doi/epdf/10.1002/chem.202101388
Permanent Link: http://hdl.handle.net/11104/0328398 - 8.0544612 - BFÚ 2022 RIV DE eng J - Journal Article
de Paiva, R. E. F. - Peterson, E. J. - Malina, Jaroslav - Zoepfl, M. - Hampton, J. D. - Johnson, W. E. - Graminha, A. - Ourahmane, A. - McVoy, M. A. - Brabec, Viktor - Berners-Price, S.J. - Farrell, N.P.
On the Biology of Werner's Complex.
Angewandte Chemie - International Edition. Roč. 60, č. 31 (2021), s. 17123-17130. ISSN 1433-7851. E-ISSN 1521-3773
R&D Projects: GA ČR(CZ) GC20-14082J
Institutional support: RVO:68081707
Keywords : heparan-sulfate proteoglycan * platinum complexes * cell-surface * dna-binding * entry * recognition
OECD category: Physical chemistry
Impact factor: 16.823, year: 2021
Method of publishing: Open access
https://onlinelibrary.wiley.com/doi/10.1002/anie.202105019
Permanent Link: http://hdl.handle.net/11104/0321449 - 9.0536139 - BFÚ 2021 RIV DE eng J - Journal Article
Hrabina, Ondřej - Malina, Jaroslav - Scott, P. - Brabec, Viktor
Cationic Fe-II Triplex-Forming Metallohelices as DNA Bulge Binders.
Chemistry - A European Journal. Roč. 2020, č. 2020 (2020). ISSN 0947-6539. E-ISSN 1521-3765
R&D Projects: GA ČR(CZ) GA20-00735S
Institutional support: RVO:68081707
Keywords : recognition * binding * bpm=2,2'-bipyrimidine * 2-aminopurine * complex * protein
OECD category: Analytical chemistry
Impact factor: 5.236, year: 2020
Method of publishing: Open access with time embargo
https://chemistry-europe.onlinelibrary.wiley.com/doi/epdf/10.1002/chem.202004060
Permanent Link: http://hdl.handle.net/11104/0313964 - 10.0536128 - BFÚ 2021 RIV US eng J - Journal Article
Malina, Jaroslav - Farrell, N.P. - Brabec, Viktor
Substitution-Inert Polynuclear Platinum Complexes Inhibit Reverse Transcription Preferentially in RNA Triplex-Forming Templates.
Inorganic Chemistry. Roč. 59, č. 20 (2020), s. 15135-15143. ISSN 0020-1669. E-ISSN 1520-510X
R&D Projects: GA ČR(CZ) GC20-14082J
Institutional support: RVO:68081707
Keywords : RNA * Triplex-Forming * Substitution-Inert Polynuclear Platinum Complexes
OECD category: Inorganic and nuclear chemistry
Impact factor: 5.165, year: 2020
Method of publishing: Limited access
https://pubs.acs.org/doi/10.1021/acs.inorgchem.0c02070
Permanent Link: http://hdl.handle.net/11104/0313952