Search results

  1. 1.
    0561287 - ÚMG 2023 RIV CH eng J - Journal Article
    Talianova, V. - Kejik, Z. - Kaplánek, R. - Veselá, K. - Abramenko, N. - Lacina, L. - Strnadová, K. - Dvořánková, B. - Martásek, P. - Masarik, M. - Houdová Megová, M. - Bušek, P. - Křížová, J. - Zdražilová, L. - Hansíková, H. - Vlčák, Erik - Filimonenko, Vlada - Šedo, A. - Smetana, K. - Jakubek, M.
    New-Generation Heterocyclic Bis-Pentamethinium Salts as Potential Cytostatic Drugs with Dual IL-6R and Mitochondria-Targeting Activity.
    Pharmaceutics. Roč. 14, č. 8 (2022), č. článku 1712. E-ISSN 1999-4923
    R&D Projects: GA MŠMT(CZ) EF16_019/0000785; GA MŠMT LX22NPO5102; GA MŠMT(CZ) LM2018129; GA MŠMT(CZ) EF18_046/0016045; GA MŠMT(CZ) EF16_013/0001775
    Research Infrastructure: EATRIS-CZ III - 90133
    Institutional support: RVO:68378050
    Keywords : IL-6R synthetic inhibitors * mitochondria * cancer
    OECD category: Pharmacology and pharmacy
    Impact factor: 5.4, year: 2022
    Method of publishing: Open access
    https://www.mdpi.com/1999-4923/14/8/1712
    Permanent Link: https://hdl.handle.net/11104/0333975
    FileDownloadSizeCommentaryVersionAccess
    pharmaceutics-14-01712.pdf03.4 MBPublisher’s postprintopen-access
     
     
  2. 2.
    0544017 - ÚI 2022 RIV CH eng J - Journal Article
    Balážiová, E. - Výmola, P. - Hrabal, P. - Mateu, R. - Zubal, M. - Tomáš, R. - Netuka, D. - Kramář, F. - Zemanová, Z. - Svobodová, K. - Brabec, Marek - Šedo, A. - Bušek, P.
    Fibroblast Activation Protein Expressing Mesenchymal Cells Promote Glioblastoma Angiogenesis.
    Cancers (Basel). Roč. 13, č. 13 (2021), č. článku 3304. E-ISSN 2072-6694
    R&D Projects: GA MZd NU21-04-00100
    Institutional support: RVO:67985807
    Keywords : glioblastoma * angiogenesis * microenvironment * fibroblast activation protein * seprase * angiopoietin * vessel destabilisation
    OECD category: Statistics and probability
    Impact factor: 6.575, year: 2021
    Method of publishing: Open access
    http://dx.doi.org/10.3390/cancers13133304
    Permanent Link: http://hdl.handle.net/11104/0321082
    FileDownloadSizeCommentaryVersionAccess
    0544017-aoa.pdf12 MBOA CC BY 4.0Publisher’s postprintopen-access
     
     
  3. 3.
    0523934 - ÚOCHB 2021 RIV NL eng J - Journal Article
    Šimková, Adéla - Bušek, P. - Šedo, A. - Konvalinka, Jan
    Molecular recognition of fibroblast activation protein for diagnostic and therapeutic applications.
    Biochimica Et Biophysica Acta-Proteins and Proteomics. Roč. 1868, č. 7 (2020), č. článku 140409. ISSN 1570-9639. E-ISSN 1878-1454
    R&D Projects: GA MZd(CZ) NV15-31379A; GA MŠMT(CZ) LM2015064; GA MŠMT(CZ) EF16_019/0000729
    Institutional support: RVO:61388963
    Keywords : fibroblast activation protein * FAP inhibitors * FAP substrates * cancer tissue targeting * activity-based probes
    OECD category: Biochemistry and molecular biology
    Impact factor: 3.036, year: 2020
    Method of publishing: Limited access
    https://www.sciencedirect.com/science/article/abs/pii/S1570963920300546
    Permanent Link: http://hdl.handle.net/11104/0308229
     
     
  4. 4.
    0481818 - ÚOCHB 2018 RIV US eng J - Journal Article
    Dvořáková, Petra - Bušek, P. - Knedlík, Tomáš - Schimer, Jiří - Etrych, Tomáš - Kostka, Libor - Stollinová Šromová, L. - Šubr, Vladimír - Šácha, Pavel - Šedo, A. - Konvalinka, Jan
    Inhibitor-decorated Polymer Conjugates Targeting Fibroblast Activation Protein.
    Journal of Medicinal Chemistry. Roč. 60, č. 20 (2017), s. 8385-8393. ISSN 0022-2623. E-ISSN 1520-4804
    R&D Projects: GA MZd(CZ) NV15-31379A; GA MŠMT(CZ) LM2015064; GA MŠMT LO1302
    Institutional support: RVO:61388963 ; RVO:61389013
    Keywords : dipeptidyl peptidase IV * metastatic colorectal cancer * integral membrane protease
    OECD category: Biochemistry and molecular biology; Polymer science (UMCH-V)
    Impact factor: 6.253, year: 2017
    Permanent Link: http://hdl.handle.net/11104/0277469
     
     
  5. 5.
    0460195 - ÚI 2017 RIV CH eng J - Journal Article
    Bušek, P. - Vaníčková, Z. - Hrabal, P. - Brabec, Marek - Frič, P. - Zavoral, M. - Škrha, J. - Kmochová, K. - Laclav, M. - Bunganič, B. - Augustyns, K. - Van Der Veken, P. - Šedo, A.
    Increased Tissue and Circulating Levels of Dipeptidyl Peptidase-IV Enzymatic Activity in Patients with Pancreatic Ductal Adenocarcinoma.
    Pancreatology. Roč. 16, č. 5 (2016), s. 829-838. ISSN 1424-3903. E-ISSN 1424-3911
    Grant - others:GA MZd(CZ) NT14254
    Institutional support: RVO:67985807
    Keywords : Diabetes mellitus * Fibroblast activation protein alpha * Peptide hydrolases * Plasma * Stromal cells
    Subject RIV: FD - Oncology ; Hematology
    Impact factor: 2.580, year: 2016
    Permanent Link: http://hdl.handle.net/11104/0260315
     
     
  6. 6.
    0387877 - ÚMG 2013 RIV GB eng J - Journal Article
    Busek, P. - Stremeňová, J. - Sromová, L. - Hilser, M. - Balaziová, E. - Kosek, D. - Trylcová, J. - Strnad, Hynek - Křepela, E. - Šedo, A.
    Dipeptidyl peptidase-IV inhibits glioma cell growth independent of its enzymatic activity.
    International Journal of Biochemistry and Cell Biology. Roč. 44, č. 5 (2012), s. 738-747. ISSN 1357-2725. E-ISSN 1878-5875
    Institutional support: RVO:68378050
    Keywords : protease * tumour suppression * primary cell cultures * astrocytoma
    Subject RIV: EB - Genetics ; Molecular Biology
    Impact factor: 4.152, year: 2012
    Permanent Link: http://hdl.handle.net/11104/0218430
     
     
  7. 7.
    0380301 - FGÚ 2013 RIV ES eng J - Journal Article
    Mareš, Vladislav - Stremeňová, J. - Lisá, Věra - Kozáková, Hana - Marek, J. - Syrůček, M. - Šoula, O. - Šedo, A.
    Compartment- and malignance-dependent up-regulation of gamma-glutamyltranspeptidase and dipetidylpeptidase-IV activity in human brain gliomas.
    Histology and Histopathology. Roč. 27, č. 7 (2012), s. 931-940. ISSN 0213-3911. E-ISSN 1699-5848
    Institutional research plan: CEZ:AV0Z50110509; CEZ:AV0Z50200510
    Keywords : gamma-glutamyltranspeptidase * dipeptidylpeptidase IV-like activity * CD26 * FAP-1 alpha * human gliomas
    Subject RIV: FD - Oncology ; Hematology
    Impact factor: 2.281, year: 2012
    Permanent Link: http://hdl.handle.net/11104/0211042
     
     
  8. 8.
    0352515 - FGÚ 2011 RIV GR eng J - Journal Article
    Stremeňová, J. - Mareš, Vladislav - Lisá, Věra - Hilser, M. - Křepela, E. - Vaníčková, Z. - Syrůček, M. - Šoula, O. - Šedo, A.
    Expression of dipeptidyl peptidase-IV activity and/or structure homologs in human meningiomas.
    International Journal of Oncology. Roč. 36, č. 2 (2010), s. 351-358. ISSN 1019-6439. E-ISSN 1791-2423
    Institutional research plan: CEZ:AV0Z50110509
    Keywords : meningioma * CXCR4 * DPP4
    Subject RIV: FH - Neurology
    Impact factor: 2.571, year: 2010
    Permanent Link: http://hdl.handle.net/11104/0192007
     
     
  9. 9.
    0142521 - FGU-C 20030149 RIV US eng J - Journal Article
    Malík, Radek - Bušek, P. - Mareš, Vladislav - Ševčík, J. - Kleibl, Z. - Šedo, A.
    Dipeptidyl peptidase-IV activity and/or structure homologues (DASH) in transformed neuroectodermal cells.
    Advances in Experimental Medicine and Biology. Roč. 524, - (2003), s. 95-102. ISSN 0065-2598. E-ISSN 2214-8019.
    [International Conference on Dipeptidyl Aminopeptidases. Berlin, 26.09.2002-28.09.2002]
    R&D Projects: GA ČR GA301/02/0962
    Grant - others:GA UK(CZ) 7/2002/C
    Institutional research plan: CEZ:AV0Z5011922
    Keywords : DASH molecules * DPP-IV activity * glioma cells
    Subject RIV: FD - Oncology ; Hematology
    Permanent Link: http://hdl.handle.net/11104/0040222
     
     
  10. 10.
    0142474 - FGU-C 20030088 RIV ES eng J - Journal Article
    Mareš, Vladislav - Lisá, Věra - Malík, Radek - Kozáková, Hana - Šedo, A.
    Cisplatin induced gamma-glutamyltransferase up-regulation, hypertrophy and differentiation in astrocytic glioma cells in culture.
    Histology and Histopathology. Roč. 18, č. 3 (2003), s. 687-693. ISSN 0213-3911. E-ISSN 1699-5848
    R&D Projects: GA ČR GA301/02/0962
    Institutional research plan: CEZ:AV0Z5020903; CEZ:AV0Z5011922
    Keywords : glioma * cisplatin * gamma-glutamytranspeptidase
    Subject RIV: FD - Oncology ; Hematology
    Impact factor: 1.830, year: 2003
    Permanent Link: http://hdl.handle.net/11104/0040177
     
     

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