Search results
- 1.0543910 - FGÚ 2022 RIV GB eng J - Journal Article
Witte, F. - Ruiz-Orera, J. - Mattioli, C. C. - Blachut, S. - Adami, E. - Schulz, J. F. - Schneider-Lunitz, V. - Hummel, O. - Patone, G. - Mücke, M. B. - Šilhavý, Jan - Heinig, M. - Bottolo, L. - Sanchis, D. - Vingron, M. - Chekulaeva, M. - Pravenec, Michal - Hubner, N. - van Heesch, S.
A trans locus causes a ribosomopathy in hypertrophic hearts that affects mRNA translation in a protein length-dependent fashion.
Genome Biology. Roč. 22, č. 1 (2021), č. článku 191. ISSN 1474-760X. E-ISSN 1474-760X
Grant - others:AV ČR(CZ) AP1502
Program: Akademická prémie - Praemium Academiae
Institutional support: RVO:67985823
Keywords : genetic variation * trans QTL mapping * translational efficiency * ribosome profiling * cardiac hypertrophy * spontaneously hypertensive rats (SHR)
OECD category: Cardiac and Cardiovascular systems
Impact factor: 18.010, year: 2021
Method of publishing: Open access
https://doi.org/10.1186/s13059-021-02397-w
Permanent Link: http://hdl.handle.net/11104/0321014 - 2.0474003 - FGÚ 2018 RIV GB eng J - Journal Article
Coan, P. M. - Hummel, O. - Diaz, A. G. - Barrier, M. - Alfazema, N. - Norsworthy, P. J. - Pravenec, Michal - Petretto, E. - Hübner, N. - Aitman, T. J.
Genetic, physiological and comparative genomic studies of hypertension and insulin resistance in the spontaneously hypertensive rat.
Disease Models & Mechanisms. Roč. 10, č. 3 (2017), s. 297-306. ISSN 1754-8403. E-ISSN 1754-8411
R&D Projects: GA ČR(CZ) GAP301/12/0696
Institutional support: RVO:67985823
Keywords : rat * congenic * genomic * hypertension * insulin resistance
OECD category: Endocrinology and metabolism (including diabetes, hormones)
Impact factor: 4.398, year: 2017
Permanent Link: http://hdl.handle.net/11104/0271098 - 3.0429012 - FGÚ 2015 RIV US eng J - Journal Article
Rintisch, C. - Heinig, M. - Bauerfeind, A. - Schafer, S. - Mieth, Ch. - Patone, G. - Hummel, O. - Chen, W. - Cook, S. - Cuppen, E. - Colomé-Tatché, M. - Johannes, F. - Jansen, R. C. - Neil, H. - Werner, M. - Pravenec, Michal - Vingron, M. - Hubner, N.
Natural variation of histone modification and its impact on gene expression in the rat genome.
Genome Research. Roč. 24, JUN (2014), s. 942-953. ISSN 1088-9051. E-ISSN 1549-5469
R&D Projects: GA MŠMT(CZ) 7E10067; GA ČR(CZ) GAP301/10/0290; GA MŠMT(CZ) LL1204
Institutional support: RVO:67985823
Keywords : ChIP-seq * histone modification * gene expression * genetic linkage analysis
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 14.630, year: 2014
Permanent Link: http://hdl.handle.net/11104/0234214 - 4.0348257 - FGÚ 2011 RIV GB eng J - Journal Article
Heinig, M. - Petretto, E. - Wallace, C. - Bottolo, L. - Rotival, M. - Lu, H. - Li, Y. - Sarwar, R. - Langley, S. R. - Bauerfeind, A. - Hummel, O. - Lee, Y. A. - Paskas, S. - Rintisch, C. - Saar, K. - Cooper, J. - Buchan, R. - Gray, C. C. - Cyster, J. G. - Erdmann, J. - Hengstenberg, C. - Maouche, S. - Ouwehand, W. H. - Rice, C. M. - Samani, N. J. - Schunkert, H. - Goodall, A. H. - Schulz, H. - Roider, H. G. - Vingron, M. - Blankenberg, S. - Münzel, T. - Zeller, T. - Szymczak, S. - Ziegler, A. - Tiret, L. - Smyth, D. J. - Pravenec, Michal - Aitman, T. J. - Cambien, F. - Clayton, D. - Todd, J. A. - Hubner, N. - Cook, S.A.
A trans-acting locus regulates an anti-viral expression network and type 1 diabetes risk.
Nature. Roč. 467, č. 7314 (2010), s. 460-464. ISSN 0028-0836. E-ISSN 1476-4687
R&D Projects: GA MŠMT(CZ) 1M0520; GA ČR GAP301/10/0290
Institutional research plan: CEZ:AV0Z50110509
Keywords : IRF7 driven inflammatory network * Ebi2 * type 1 diabetes
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 36.104, year: 2010
Permanent Link: http://hdl.handle.net/11104/0188834 - 5.0345074 - FGÚ 2011 RIV US eng J - Journal Article
Atanur, S. S. - Birol, I. - Guryev, V. - Hirst, M. - Hummel, O. - Morrissey, C. - Behmoaras, J. - Fernandez-Suarez, X.M. - Johnson, M. D. - McLaren, W. M. - Patone, G. - Petretto, E. - Plessy, Ch. - Rockland, K. S. - Rockland, Ch. - Saar, K. - Zhao, Y. - Carninci, P. - Flicek, P. - Kurtz, T. - Cuppen, E. - Pravenec, Michal - Hubner, N. - Jones, S. J. M. - Birney, E. - Aitman, T. J.
The genome sequence of the spontaneously hypertensive rat: Analysis and functional significance.
Genome Research. Roč. 20, č. 6 (2010), s. 791-803. ISSN 1088-9051. E-ISSN 1549-5469
R&D Projects: GA MŠMT(CZ) 1M0520
Grant - others:EC(XE) LSHG-CT-2005-019015; HHMI(US) HHMI; Transatlantic network of excellence(US) Foundation Leducq
Institutional research plan: CEZ:AV0Z50110509
Keywords : spontaneously hypertensive rat * genome sequence * genetics
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 13.588, year: 2010
Permanent Link: http://hdl.handle.net/11104/0186428 - 6.0307224 - FGÚ 2008 RIV US eng J - Journal Article
Saar, K. - Beck, A. - Bihoreau, M. T. - Birney, E. - Brocklebank, D. - Chen, Y. - Cuppen, E. - Demonchy, S. - Dopazo, J. - Flicek, P. - Foglio, M. - Fujiyama, A. - Gut, I. G. - Gauguier, D. - Guigo, R. - Guryev, V. - Heinig, M. - Hummel, O. - Jahn, N. - Klages, S. - Křen, Vladimír - Kube, M. - Kuhl, H. - Kuramoto, T. - Pravenec, Michal
SNP and haplotype mapping for genetic analysis in the rat.
[SNP a haplotypové mapování pro genetické analýzy u potkana.]
Nature Genetics. Roč. 40, č. 5 (2008), s. 560-566. ISSN 1061-4036. E-ISSN 1546-1718
R&D Projects: GA MŠMT(CZ) 1P05ME791; GA MŠMT(CZ) 1M0520; GA MŠMT(CZ) ME08006
Grant - others:HHMI(US) 55005624; -(XE) LSHG-CT-2005-019015
Institutional research plan: CEZ:AV0Z50110509
Source of funding: N - Non-public resources ; R - Framework programmes of European Commission
Keywords : SNP * rat * complete map
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 30.259, year: 2008
Permanent Link: http://hdl.handle.net/11104/0160047 - 7.0001012 - FGÚ 2006 RIV US eng J - Journal Article
Hubner, N. - Wallace, C.A. - Zimdahl, H. - Petretto, E. - Schulz, H. - Maciver, F. - Mueller, M. - Hummel, O. - Monti, J. - Zídek, Václav - Musilová, Alena - Křen, Vladimír - Causton, H. - Game, L. - Born, G. - Schmidt, S. - Müller, A. - Cook, S.A. - Kurtz, T. W. - Whittaker, J. - Pravenec, Michal - Aitman, T. J.
Integrated transcriptional profiling and linkage analysis for identification of genes underlying disease.
[Integrace analýzy profilů genové exprese s vazebnými analýzami pro identifikaci genů odpovědných za choroby.]
Nature Genetics. Roč. 37, č. 3 (2005), s. 243-253. ISSN 1061-4036. E-ISSN 1546-1718
R&D Projects: GA ČR(CZ) GA301/03/0751; GA ČR(CZ) GA301/04/0390
Grant - others:HHMI(US) 55000331; FIRCA(US) TW01236; Wellcome Trust(GB) GR069065MF
Institutional research plan: CEZ:AV0Z50110509
Keywords : genetical genomics * RI strains * spontaneously hypertensive rats
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 25.797, year: 2005
Permanent Link: http://hdl.handle.net/11104/0018207