Search results
- 1.0576971 - BFÚ 2024 RIV GB eng J - Journal Article
Holmej, J. A. - Vondráček, Jan - Machala, M. - Lagadic-Gossmann, D. - Vogel, C. - Le Ferrec, E. - Sparfel, L. - Ovrevik, J.
Lung cancer associated with combustion particles and fine particulate matter (PM2.5) The roles of polycyclic aromatic hydrocarbons (PAHs) and the aryl hydrocarbon receptor (AhR).
Biochemical Pharmacology. Roč. 216, OCT 2023 (2023), č. článku 115801. ISSN 0006-2952. E-ISSN 1873-2968
R&D Projects: GA ČR(CZ) GA21-00533S
Institutional support: RVO:68081707
Keywords : Air pollution * Diesel exhaust * Smoking * Occupational exposure * Carcinogenesis * Genotoxicity * Inflammation * Tumor promotion * Tumor microenvironment
OECD category: Pharmacology and pharmacy
Impact factor: 5.8, year: 2022
Method of publishing: Open access
https://www.sciencedirect.com/science/article/pii/S0006295223003921?via%3Dihub
Permanent Link: https://hdl.handle.net/11104/0350475 - 2.0571976 - BFÚ 2024 RIV NL eng J - Journal Article
Marvanová, S. - Pěnčíková, K. - Palková, L. - Ciganek, M. - Petráš, Jiří - Lněničková, Anna - Vondráček, Jan - Machala, M.
Benzo[b]naphtho[d]thiophenes and naphthylbenzo[b]thiophenes: Their aryl hydrocarbon receptor-mediated activities and environmental presence.
Science of the Total Environment. Roč. 879, JUN 25 2023 (2023), č. článku 162924. ISSN 0048-9697. E-ISSN 1879-1026
R&D Projects: GA ČR(CZ) GA21-00533S
Institutional support: RVO:68081707
Keywords : Polycyclic aromatic sulfur heterocyclic * compounds * AhR activity * Gap junctional intercellular communication * Airborne particulate matter * Freshwater sediments
OECD category: Ecology
Impact factor: 9.8, year: 2022
Method of publishing: Limited access
https://www.sciencedirect.com/science/article/pii/S0048969723015401?via%3Dihub
Permanent Link: https://hdl.handle.net/11104/0349923 - 3.0561061 - BFÚ 2023 RIV CH eng J - Journal Article
Karasová, Martina - Procházková, Jiřina - Tylichová, Zuzana - Fedr, Radek - Ciganek, M. - Machala, M. - Dvořák, Z. - Vyhlidalova, B. - Zuvalova, I. - Ehrmann, J. - Bouchal, J. - Andrysík, Z. - Vondráček, Jan
Inhibition of Aryl Hydrocarbon Receptor (AhR) Expression Disrupts Cell Proliferation and Alters Energy Metabolism and Fatty Acid Synthesis in Colon Cancer Cells.
Cancers (Basel). Roč. 14, č. 17 (2022), č. článku 4245. E-ISSN 2072-6694
R&D Projects: GA ČR(CZ) GA19-00236S; GA MZd(CZ) NU21-03-00421
Institutional support: RVO:68081707
Keywords : colon cancer cells * AhR * metabolism * proliferation * fatty acid synthesis * Akt pathway
OECD category: Oncology
Impact factor: 5.2, year: 2022
Method of publishing: Open access
https://www.mdpi.com/2072-6694/14/17/4245
Permanent Link: https://hdl.handle.net/11104/0340614 - 4.0556112 - BFÚ 2023 RIV NL eng J - Journal Article
Šimečková, P. - Pěnčíková, K. - Kováč, O. - Slavík, J. - Parenicova, M. - Vondráček, Jan - Machala, M.
In vitro profiling of toxic effects of environmental polycyclic aromatic hydrocarbons on nuclear receptor signaling, disruption of endogenous metabolism and induction of cellular stress.
Science of the Total Environment. Roč. 815, APR 1 2022 (2022), č. článku 151967. ISSN 0048-9697. E-ISSN 1879-1026
R&D Projects: GA ČR(CZ) GA21-00533S
Institutional support: RVO:68081707
Keywords : pregnane-x-receptor * primary human hepatocytes * aryl-hydrocarbon * estrogen-receptor * mediated activity * hepg2 cells * cross-talk * activation
OECD category: Ecology
Impact factor: 9.8, year: 2022
Method of publishing: Limited access
https://www.sciencedirect.com/science/article/pii/S0048969721070431?via%3Dihub
Permanent Link: https://hdl.handle.net/11104/0339759 - 5.0555924 - BFÚ 2023 RIV CH eng J - Journal Article
Vazquez-Gomez, Gerardo - Karasová, Martina - Tylichová, Zuzana - Kabátková, Markéta - Hampl, A. - Matthews, J. - Neca, J. - Ciganek, M. - Machala, M. - Vondráček, Jan
Aryl Hydrocarbon Receptor (AhR) Limits the Inflammatory Responses in Human Lung Adenocarcinoma A549 Cells via Interference with NF-kappa B Signaling.
Cells. Roč. 11, č. 4 (2022), č. článku 707. E-ISSN 2073-4409
R&D Projects: GA ČR(CZ) GA18-00145S
Institutional support: RVO:68081707
Keywords : polycyclic aromatic-hydrocarbons * particulate matter * epithelial-cells * cigarette-smoke * synergistic induction * oxidative stress * air-pollution
OECD category: Cell biology
Impact factor: 6, year: 2022
Method of publishing: Open access
https://www.mdpi.com/2073-4409/11/4/707
Permanent Link: https://hdl.handle.net/11104/0340062 - 6.0555644 - BFÚ 2022 RIV AE eng J - Journal Article
Vondráček, Jan - Machala, M.
The Role of Metabolism in Toxicity of Polycyclic Aromatic Hydrocarbons and their Non-genotoxic Modes of Action.
Current Drug Metabolism. Roč. 22, č. 8 (2021), s. 584-595. ISSN 1389-2002. E-ISSN 1875-5453
R&D Projects: GA ČR(CZ) GA18-00145S
Institutional support: RVO:68081707
Keywords : junctional intercellular communication * activated protein-kinases * cancer-risk assessment * estrogen-receptor-alpha * cell-cycle progression * growth-factor receptor * knockout mouse lines
OECD category: Biochemistry and molecular biology
Impact factor: 3.408, year: 2021
Method of publishing: Limited access
https://www.eurekaselect.com/article/111851
Permanent Link: http://hdl.handle.net/11104/0330101 - 7.0554488 - BFÚ 2022 RIV CH eng J - Journal Article
Machala, M. - Slavík, J. - Kováč, O. - Procházková, J. - Pěnčíková, K. - Parenicova, M. - Straková, N. - Kotouček, J. - Kulich, P. - Mollerup, S. - Vondráček, Jan - Hýžd'alová, M.
Changes in Sphingolipid Profile of Benzo[a]pyrene-Transformed Human Bronchial Epithelial Cells Are Reflected in the Altered Composition of Sphingolipids in Their Exosomes.
International Journal of Molecular Sciences. Roč. 22, č. 17 (2021), č. článku 9195. E-ISSN 1422-0067
Institutional support: RVO:68081707
Keywords : mesenchymal transition * tumor-growth * cancer * lung * globotriaosylceramide * transformation
OECD category: Biochemistry and molecular biology
Impact factor: 6.208, year: 2021
Method of publishing: Open access
https://www.mdpi.com/1422-0067/22/17/9195
Permanent Link: http://hdl.handle.net/11104/0329203 - 8.0554413 - BFÚ 2022 RIV IE eng J - Journal Article
Slováčková, J. - Slavík, J. - Kulich, P. - Večeřa, J. - Kováč, O. - Paculova, H. - Straková, N. - Fedr, Radek - Silva, J. P. - Carvalho, F. - Machala, M. - Procházková, Jiřina
Polychlorinated environmental toxicants affect sphingolipid metabolism during neurogenesis in vitro.
Toxicology. Roč. 463, NOV 2021 (2021), č. článku 152986. ISSN 0300-483X
R&D Projects: GA ČR(CZ) GA21-11585S
Institutional support: RVO:68081707
Keywords : junctional intercellular communication * ceramide 1-phosphate * pcb congeners * biphenyls * sulfatide * cells
OECD category: Pharmacology and pharmacy
Impact factor: 4.571, year: 2021
Method of publishing: Limited access
https://www.sciencedirect.com/science/article/pii/S0300483X21003085?via%3Dihub
Permanent Link: http://hdl.handle.net/11104/0329110 - 9.0551564 - ÚEM 2022 RIV NL eng J - Journal Article
Líbalová, Helena - Závodná, Táňa - Vrbová, Kristýna - Sikorová, Jitka - Vojtisek-Lom, M. - Beránek, V. - Pechout, Martin - Kléma, J. - Cigánek, M. - Machala, M. - Neca, J. - Rössner ml., Pavel - Topinka, Jan
Transcription profiles in BEAS-2B cells exposed to organic extracts from particulate emissions produced by a port-fuel injection vehicle, fueled with conventional fossil gasoline and gasoline-ethanol blend.
Mutation Research - Genetic Toxicology and Environmental Mutagenesis. Roč. 872, dec (2021), č. článku 503414. ISSN 1383-5718. E-ISSN 1879-3592
R&D Projects: GA ČR(CZ) GJ18-06548Y; GA MŠMT(CZ) LM2018124; GA MŠMT(CZ) LM2018133
Institutional support: RVO:68378041
Keywords : particulate matter emissions * gasoline * alternative fuels * toxicity * gene expression profiling
OECD category: Toxicology
Impact factor: 3.189, year: 2021
Method of publishing: Open access
https://www.sciencedirect.com/science/article/pii/S1383571821001054?via%3Dihub
Permanent Link: http://hdl.handle.net/11104/0326830 - 10.0541994 - BFÚ 2022 RIV GB eng J - Journal Article
Hýžd'alová, M. - Procházková, J. - Strapáčová, S. - Svrzkova, L. - Vacek, Ondřej - Fedr, Radek - Andrysik, Z. - Hrubá, E. - Líbalová, Helena - Kléma, J. - Topinka, Jan - Mašek, J. - Souček, Karel - Vondráček, Jan - Machala, M.
A prolonged exposure of human lung carcinoma epithelial cells to benzo[a]pyrene induces p21-dependent epithelial-to-mesenchymal transition (EMT)-like phenotype.
Chemosphere. Roč. 263, JAN 2021 (2021), č. článku 128126. ISSN 0045-6535. E-ISSN 1879-1298
Institutional support: RVO:68081707 ; RVO:68378041
Keywords : aryl-hydrocarbon receptor * polycyclic aromatic-hydrocarbons * tgf-beta * a549 cells * cigarette-smoking
OECD category: Cell biology; Cell biology (UEM-P)
Impact factor: 8.943, year: 2021
Method of publishing: Open access
https://www.sciencedirect.com/science/article/pii/S0045653520323213?via%3Dihub
Permanent Link: http://hdl.handle.net/11104/0319497