Search results
- 1.0573031 - ÚOCHB 2024 RIV US eng J - Journal Article
Zmudzinski, M. - Rut, W. - Olech, K. - Granda, J. - Giurg, M. - Burda-Grabowska, M. - Kaleta, R. - Zgarbová, Michala - Kasprzyk, R. - Zhang, L. - Sun, X. - Lv, Z. - Nayak, D. - Kesik-Brodacka, M. - Olsen, S. K. - Weber, Jan - Hilgenfeld, R. - Jemielity, J. - Drag, M.
Ebselen derivatives inhibit SARS-CoV-2 replication by inhibition of its essential proteins: PLpro and Mpro proteases, and nsp14 guanine N7-methyltransferase.
Scientific Reports. Roč. 13, June (2023), č. článku 9161. ISSN 2045-2322. E-ISSN 2045-2322
R&D Projects: GA MŠMT(CZ) EF16_019/0000729
Institutional support: RVO:61388963
Keywords : organoselenium compounds * synthetic methodology * SARS
OECD category: Virology
Impact factor: 4.6, year: 2022
Method of publishing: Open access
https://doi.org/10.1038/s41598-023-35907-w
Permanent Link: https://hdl.handle.net/11104/0343565 - 2.0194573 - UOCHB-X 20020244 RIV GB eng J - Journal Article
Weber, Jan - Mesters, J. R. - Lepšík, Martin - Prejdová, Jana - Švec, Martin - Šponarová, Jana - Mlčochová, Petra - Skalická, Kristina - Stříšovský, Kvido - Kondrová, Taťána - Souček, Milan - Machala, L. - Staňková, M. - Vondrášek, Jiří - Klimkait, T. - Kraeusslich, H. G. - Hilgenfeld, R. - Konvalinka, Jan
Unusual binding mode of an HIV-1 protease inhibitor explains its potency against multi-grug-resistant virus strains.
Journal of Molecular Biology. Roč. 324, - (2002), s. 739-754. ISSN 0022-2836. E-ISSN 1089-8638
R&D Projects: GA ČR GA203/00/0828; GA MŠMT LN00A032; GA MZd NI6339
Institutional research plan: CEZ:AV0Z4055905
Keywords : HIV protease inhibitor
Subject RIV: CE - Biochemistry
Impact factor: 5.359, year: 2002
Permanent Link: http://hdl.handle.net/11104/0090248 - 3.0190879 - UMG-J 990292 RIV US eng J - Journal Article
Lange-Savage, G. - Berchtold, H. - Liesum, A. - Budt, K. H. - Peyman, A. - Knolle, J. - Sedláček, Juraj - Fábry, Milan - Hilgenfeld, R.
Structure of HOE-BAY 793 complexed to human immunodeficiency virus (HIV-1) protease in two different crystal forms.
European Journal of Biochemistry. Roč. 248, - (1997), s. 313-322. ISSN 0014-2956
R&D Projects: GA MZd IZ3272
Grant - others:Copernicus(FR) CEC9329
Subject RIV: CE - Biochemistry
Impact factor: 3.136, year: 1997
Permanent Link: http://hdl.handle.net/11104/0086642 - 4.0190661 - UMG-J 990051 RIV GB eng J - Journal Article
Krásný, Libor - Mesters, J. R. - Tieleman, L. N. - Kraal, B. - Fučík, Vladimír - Hilgenfeld, R. - Jonák, Jiří
Structure and Expression of Elongation Factor Tu from Bacillus stearothermophilus.
Journal of Molecular Biology. Roč. 283, č. 2 (1998), s. 371-381. ISSN 0022-2836. E-ISSN 1089-8638
R&D Projects: GA ČR GA204/98/0863
Grant - others:HHMI(US) 75195-540305
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 5.803, year: 1998
Permanent Link: http://hdl.handle.net/11104/0086443 - 5.0189963 - UMBR-M 20033011 RIV CZ eng J - Journal Article
Kutá-Smatanová, Ivana - Hogg, T. - Hilgenfeld, R. - Grandori, R. - Carey, J. - Vácha, František - Štys, D.
Proteins and their crystals.
Materials Structure in Chemistry, Biology, Physics and Technology. Roč. 10, - (2003), s. 30-31. ISSN 1211-5894
R&D Projects: GA MŠMT LN00A141; GA ČR GA206/00/D007
Institutional research plan: CEZ:MSM 123100001
Keywords : antiviral proteins
Subject RIV: CD - Macromolecular Chemistry
Permanent Link: http://hdl.handle.net/11104/0085760 - 6.0154625 - MBU-M 20020226 RIV DK eng J - Journal Article
Hogg, T. - Smatanová, I. - Bezouška, Karel - Ulbrich, N. - Hilgenfeld, R.
Sugar-mediated lettice contacts in crystals of a plant glycoprotein.
Acta Crystallographica Section D-Biological Crystallography. Roč. 58, - (2002), s. 1734-1739. ISSN 0907-4449
R&D Projects: GA MŠMT LN00A141
Grant - others:GA(DE) 05SH8BJA; GA(DE) Hi 611/1-3; GA-(DE) 05KSIGKA/5; GA(DE) HPRI-CT-199-0097
Institutional research plan: CEZ:MSM 113100001
Keywords : pap * glycosylation * deglycosylation
Subject RIV: EE - Microbiology, Virology
Impact factor: 1.760, year: 2002
Permanent Link: http://hdl.handle.net/11104/0001056 - 7.0044735 - ÚOCHB 2007 RIV GB eng J - Journal Article
Mesters, J. R. - Bařinka, Cyril - Li, W. - Tsukamoto, T. - Majer, P. - Slusher, B. - Konvalinka, Jan - Hilgenfeld, R.
Structure of glutamate carboxypeptidase II, a drug target in neuronal damage and prostate cancer.
[Struktura GCP II, léčebného cíle při neuronálním poškození a nádorech prostaty.]
EMBO Journal. Roč. 25, č. 6 (2006), s. 1375-1384. ISSN 0261-4189. E-ISSN 1460-2075
R&D Projects: GA ČR(CZ) GA301/03/0784; GA MŠMT 1M0508
Institutional research plan: CEZ:AV0Z40550506
Keywords : NAALADase * neurodegenerative disease * peptidase * prostate cancer
Subject RIV: CE - Biochemistry
Impact factor: 10.086, year: 2006
Permanent Link: http://hdl.handle.net/11104/0137447