Search results
- 1.0450872 - ÚMCH 2016 RIV US eng J - Journal Article
Lynn, G. M. - Laga, Richard - Darrah, P. A. - Ishizuka, A. S. - Balaci, A. J. - Dulcey, A. E. - Pechar, Michal - Pola, Robert - Gerner, M. Y. - Yamamoto, A. - Buechler, C. R. - Quinn, K. M. - Smelkinson, M. G. - Vanek, O. - Cawood, R. - Hills, T. - Vasalatiy, O. - Kastenmüller, K. - Francica, J. R. - Stutts, L. - Tom, J. K. - Ah Ryu, K. - Esser-Kahn, A. P. - Etrych, Tomáš - Fisher, K. D. - Seymour, L. W. - Seder, R. A.
In vivo characterization of the physicochemical properties of polymer-linked TLR agonists that enhance vaccine immunogenicity.
Nature Biotechnology. Roč. 33, č. 11 (2015), s. 1201-1210. ISSN 1087-0156. E-ISSN 1546-1696
R&D Projects: GA MŠMT(CZ) EE2.3.30.0029
Institutional support: RVO:61389013
Keywords : adjuvants * biomedical engineering * drug delivery
Subject RIV: CE - Biochemistry
Impact factor: 43.113, year: 2015
Permanent Link: http://hdl.handle.net/11104/0252994 - 2.0384590 - ÚMCH 2013 RIV GB eng J - Journal Article
Green, N. K. - Hale, A. - Cawood, R. - Illingworth, S. - Herbert, C. - Hermiston, T. - Šubr, Vladimír - Ulbrich, Karel - van Rooijen, N. - Seymour, L. W. - Fisher, K. D.
Tropism ablation and stealthing of oncolytic adenovirus enhances systemic delivery to tumors and improves virotherapy of cancer.
Nanomedicine. Roč. 7, č. 11 (2012), s. 1683-1695. ISSN 1743-5889. E-ISSN 1748-6963
R&D Projects: GA AV ČR IAAX00500803
Institutional research plan: CEZ:AV0Z40500505
Institutional support: RVO:61389013
Keywords : clodronate liposomes * polymer-coated adenovirus * predosing strategy
Subject RIV: CD - Macromolecular Chemistry
Impact factor: 5.260, year: 2012
Permanent Link: http://hdl.handle.net/11104/0216116 - 3.0368414 - ÚMCH 2012 RIV NL eng J - Journal Article
Seki, T. - Carroll, F. - Illingworth, S. - Green, N. - Cawood, R. - Bachtarzi, H. - Šubr, Vladimír - Fisher, K. D. - Seymour, L. W.
Tumour necrosis factor-alpha increases extravasation of virus particles into tumour tissue by activating the Rho A/Rho kinase pathway.
Journal of Controlled Release. Roč. 156, č. 3 (2011), s. 381-389. ISSN 0168-3659. E-ISSN 1873-4995
Institutional research plan: CEZ:AV0Z40500505
Keywords : drug delivery * adenovirus * vascular permeability
Subject RIV: CD - Macromolecular Chemistry
Impact factor: 5.732, year: 2011
Permanent Link: http://hdl.handle.net/11104/0202765 - 4.0362894 - ÚMCH 2012 RIV GB eng J - Journal Article
Bachtarzi, H. - Stevenson, M. - Šubr, Vladimír - Seymour, L. W. - Fisher, K. D.
E-selectin is a viable route of infection for polymer-coated adenovirus retargeting in TNF-.alpha.-activated human umbilical vein endothelial cells.
Journal of Drug Targeting. Roč. 19, č. 8 (2011), s. 690-700. ISSN 1061-186X. E-ISSN 1029-2330
Institutional research plan: CEZ:AV0Z40500505
Keywords : polymer-coated virus * vascular targeting * inflammation
Subject RIV: CD - Macromolecular Chemistry
Impact factor: 2.696, year: 2011
Permanent Link: http://hdl.handle.net/11104/0199069 - 5.0358495 - ÚMCH 2012 RIV NL eng J - Journal Article
Bachtarzi, H. - Stevenson, M. - Šubr, Vladimír - Ulbrich, Karel - Seymour, L. W. - Fisher, K. D.
Targeting adenovirus gene delivery to activated tumour-associated vasculature via endothelial selectins.
Journal of Controlled Release. Roč. 150, č. 2 (2011), s. 196-203. ISSN 0168-3659. E-ISSN 1873-4995
R&D Projects: GA MŠMT 1M0505
Institutional research plan: CEZ:AV0Z40500505
Keywords : E-selectin * pHPMA * adenovirus
Subject RIV: EI - Biotechnology ; Bionics
Impact factor: 5.732, year: 2011
Permanent Link: http://hdl.handle.net/11104/0196522 - 6.0322079 - ÚMCH 2009 RIV US eng J - Journal Article
Carlisle, R. C. - Di, Y. - Cerny, A. M. - Sonnen, A. F. P. - Sim, R. B. - Green, N. K. - Šubr, Vladimír - Ulbrich, Karel - Gilbert, R. J. C. - Fisher, K. D. - Finberg, R. W. - Seymour, L. W.
Human erythrocytes bind and inactivate type 5 adenovirus by presenting Coxsackie virus-adenovirus receptor and complement receptor 1.
[Lidské erytrocyty obsahující Coxsakie virus-adenovirus receptor a komplement receptor 1 váží a inaktivují adenovirus typu 5.]
Blood. Roč. 113, č. 9 (2009), s. 1909-1918. ISSN 0006-4971. E-ISSN 1528-0020
EU Projects: European Commission(XE) 512087 - GIANT
Institutional research plan: CEZ:AV0Z40500505
Keywords : adenovirus * erythrocyte * complement receptor 1
Subject RIV: CD - Macromolecular Chemistry
Impact factor: 10.555, year: 2009
Permanent Link: http://hdl.handle.net/11104/0170436 - 7.0306296 - ÚMCH 2008 RIV US eng J - Journal Article
Green, N. K. - Morrison, J. - Hale, S. - Briggs, S. S. - Stevenson, M. - Šubr, Vladimír - Ulbrich, Karel - Chandler, L. - Mautner, V. - Seymour, L. W. - Fisher, K. D.
Retargeting polymer coated adenovirus to the FGF receptor allows productive infection and mediates efficacy in a peritoneal model of human ovarian cancer.
[Přesměrování polymerem modifikovaného adenoviru k FGF receptorům ovlivňuje jeho účinnost a umožňuje účinné infikování peritoneálního modelu lidského ovariálního nádoru.]
Journal of Gene Medicine. Roč. 10, č. 3 (2008), s. 280-289. ISSN 1099-498X. E-ISSN 1521-2254
R&D Projects: GA ČR GA204/05/2255
Grant - others:FP6 European Union (GIANT programme)(EU) LifeSciHealth-I 512087
Institutional research plan: CEZ:AV0Z40500505
Source of funding: R - Framework programmes of European Commission
Keywords : adenovirus * targeting * gene therapy
Subject RIV: CD - Macromolecular Chemistry
Impact factor: 3.141, year: 2008
Permanent Link: http://hdl.handle.net/11104/0159363 - 8.0306294 - ÚMCH 2008 RIV US eng J - Journal Article
Carlisle, R. C. - Benjamin, R. - Briggs, S. S. - Sumner-Jones, S. - McIntosh, J. - Gill, D. - Hyde, S. - Nathwani, A. - Šubr, Vladimír - Ulbrich, Karel - Seymour, L. W. - Fisher, K. D.
Coating of adeno-associated virus with reactive polymers can ablate virus tropism, enable retargeting and provide resistance to neutralising antisera.
[Povrchová modifikace adeno-asociovaných virů reaktivními polymery může odstínit tropismus viru, umožňuje jeho přesměrování a poskytuje odolnost vůči neutralizujícímu antiséru.]
Journal of Gene Medicine. Roč. 10, č. 4 (2008), s. 400-411. ISSN 1099-498X. E-ISSN 1521-2254
R&D Projects: GA AV ČR KAN200200651
Grant - others:BBSRC SBRI(GB) 7633; FP6 European Commission Funded Research(EU) LSHB-CT-2004-512087
Institutional research plan: CEZ:AV0Z40500505
Source of funding: R - Framework programmes of European Commission
Keywords : AAV * HPMA * polymer coating
Subject RIV: CD - Macromolecular Chemistry
Impact factor: 3.141, year: 2008
Permanent Link: http://hdl.handle.net/11104/0159361 - 9.0188460 - UMCH-V 20010238 RIV GB eng J - Journal Article
Fisher, K. D. - Stallwood, Y. - Green, N. K. - Ulbrich, Karel - Mautner, V. - Seymour, L. W.
Polymer-coated adenovirus permits efficient retargeting and evades neutralising antibodies.
Gene Therapy. Roč. 8, - (2001), s. 341-348. ISSN 0969-7128. E-ISSN 1476-5462
R&D Projects: GA AV ČR KSK4055109
Institutional research plan: CEZ:AV0Z4050913
Keywords : adenovirus * gene therapy * targetting
Subject RIV: CC - Organic Chemistry
Impact factor: 5.893, year: 2001
Permanent Link: http://hdl.handle.net/11104/0084410 - 10.0188127 - UMCH-V 20000273 RIV GB eng J - Journal Article
Fisher, K. D. - Ulbrich, Karel - Šubr, Vladimír - Ward, C. M. - Mautner, V. - Blakey, D. - Seymour, L. W.
A versatile system for receptor-mediated gene delivery permits increased entry of DNA into target cells, enhanced delivery to the nucleus and elevated rates of transgene expression.
Gene Therapy. Roč. 7, č. 15 (2000), s. 1337-1343. ISSN 0969-7128. E-ISSN 1476-5462
R&D Projects: GA AV ČR KSK2055603
Grant - others:XE(XC) Copernicus IC20-CT970005
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 5.964, year: 2000
Permanent Link: http://hdl.handle.net/11104/0084121