Search results

  1. 1.
    0519413 - BC 2020 RIV GB eng J - Journal Article
    Dufková, L. - Širmarová, J. - Salát, J. - Hönig, Václav - Palus, Martin - Růžek, Daniel - Fooks, A. R. - Mansfield, K. L. - Tordo, N. - Jochmans, D. - Neyts, J. - Martina, B. - Koraka, P. - Osterhaus, D. M. E. … Total 15 authors
    Mannitol treatment is not effective in therapy of rabies virus infection in mice.
    Vaccine. Roč. 37, č. 33 (2019), s. 4710-4714. ISSN 0264-410X. E-ISSN 1873-2518
    Institutional support: RVO:60077344
    Keywords : blood-brain-barrier * innate immune-responses * central-nervous-system * permeability * delivery * Rabies * Blood-brain barrier * Mannitol * Therapy
    OECD category: Immunology
    Impact factor: 3.143, year: 2019
    Method of publishing: Limited access
    https://www.sciencedirect.com/science/article/pii/S0264410X17317814?via%3Dihub
    Permanent Link: http://hdl.handle.net/11104/0304385
     
     
  2. 2.
    0463545 - ÚOCHB 2017 RIV US eng J - Journal Article
    Plačková, Pavla - Šála, Michal - Šmídková, Markéta - Dejmek, Milan - Hřebabecký, Hubert - Nencka, Radim - Thibaut, H. J. - Neyts, J. - Mertlíková-Kaiserová, Helena
    9-Norbornyl-6-chloropurine (NCP) induces cell death through GSH depletion-associated ER stress and mitochondrial dysfunction.
    Free Radical Biology and Medicine. Roč. 97, Aug (2016), s. 223-235. ISSN 0891-5849. E-ISSN 1873-4596
    R&D Projects: GA MŠMT LO1302; GA ČR GAP303/11/1297
    Institutional support: RVO:61388963
    Keywords : glutathione-S-transferase * oxidative stress * leukemia
    Subject RIV: CE - Biochemistry
    Impact factor: 5.606, year: 2016
    http://www.sciencedirect.com/science/article/pii/S0891584916302921
    Permanent Link: http://hdl.handle.net/11104/0262713
    FileDownloadSizeCommentaryVersionAccess
    0463545.pdf52 MBPublisher’s postprintopen-access
     
     
  3. 3.
    0443135 - ÚOCHB 2016 RIV GB eng J - Journal Article
    Dejmek, Milan - Šála, Michal - Hřebabecký, Hubert - Dračínský, Martin - Procházková, Eliška - Chalupská, Dominika - Klíma, Martin - Plačková, Pavla - Hájek, Miroslav - Andrei, G. - Naesens, L. - Leyssen, P. - Neyts, J. - Balzarini, J. - Bouřa, Evžen - Nencka, Radim
    Norbornane-based nucleoside and nucleotide analogues locked in North conformation.
    Bioorganic & Medicinal Chemistry. Roč. 23, č. 1 (2015), s. 184-191. ISSN 0968-0896. E-ISSN 1464-3391
    R&D Projects: GA ČR GPP207/12/P625; GA MŠMT LO1302
    Institutional support: RVO:61388963
    Keywords : carbocyclic nucleosides * purines * norbornane * antiviral * PI4KIIalpha
    Subject RIV: CC - Organic Chemistry
    Impact factor: 2.923, year: 2015
    Permanent Link: http://hdl.handle.net/11104/0245898
     
     
  4. 4.
    0430390 - ÚOCHB 2015 RIV DE eng J - Journal Article
    Dejmek, Milan - Šála, Michal - Plačková, Pavla - Hřebabecký, Hubert - Borreda, L. M. - Neyts, J. - Dračínský, Martin - Procházková, Eliška - Jansa, Petr - Leyssen, P. - Mertlíková-Kaiserová, Helena - Nencka, Radim
    Synthesis of Novel Purine-Based Coxsackievirus Inhibitors Bearing Polycylic Substituents at the N-9 Position.
    Archiv der Pharmazie. Roč. 347, č. 7 (2014), s. 478-485. ISSN 0365-6233. E-ISSN 1521-4184
    R&D Projects: GA ČR GAP303/11/1297
    Institutional support: RVO:61388963
    Keywords : antiviral * coxsackievirus B3 * enteroviruses * phosphatidylinositol 4-kinase (PI4K) * purines
    Subject RIV: CC - Organic Chemistry
    Impact factor: 1.531, year: 2014
    Permanent Link: http://hdl.handle.net/11104/0235359
     
     
  5. 5.
    0428690 - ÚOCHB 2015 RIV GB eng J - Journal Article
    Dejmek, Milan - Hřebabecký, Hubert - Šála, Michal - Dračínský, Martin - Procházková, Eliška - Leyssen, P. - Neyts, J. - Balzarini, J. - Nencka, Radim
    From norbornane-based nucleotide analogs locked in South conformation to novel inhibitors of feline herpes virus.
    Bioorganic & Medicinal Chemistry. Roč. 22, č. 11 (2014), s. 2974-2983. ISSN 0968-0896. E-ISSN 1464-3391
    R&D Projects: GA MV VG20102015046
    Institutional support: RVO:61388963
    Keywords : carbocyclic nucleosides * nucleoside phosphonates * purine * norbornane * feline herpes virus
    Subject RIV: CC - Organic Chemistry
    Impact factor: 2.793, year: 2014
    Permanent Link: http://hdl.handle.net/11104/0234000
     
     
  6. 6.
    0391954 - ÚOCHB 2014 RIV GB eng J - Journal Article
    Krečmerová, Marcela - Jansa, Petr - Dračínský, Martin - Sázelová, Petra - Kašička, Václav - Neyts, J. - Auwerx, J. - Kiss, E. - Goris, N. - Stepan, G. - Janeba, Zlatko
    9-[2-(R)-(Phosphonomethoxy)propyl]-2,6-diaminopurine (R)-PMPDAP and its prodrugs: Optimized preparation, including identification of by-products formed, and antiviral evaluation in vitro.
    Bioorganic & Medicinal Chemistry. Roč. 21, č. 5 (2013), s. 1199-1208. ISSN 0968-0896. E-ISSN 1464-3391
    R&D Projects: GA MŠMT(CZ) ME10040
    Institutional support: RVO:61388963
    Keywords : PMPDAP * Acyclic nucleoside phosphonates * (Phosphonomethoxy)propyl * purine * antivirals * HIV
    Subject RIV: CC - Organic Chemistry
    Impact factor: 2.951, year: 2013
    Permanent Link: http://hdl.handle.net/11104/0220970
     
     
  7. 7.
    0376557 - ÚOCHB 2013 RIV GB eng J - Journal Article
    Hřebabecký, Hubert - Dejmek, Milan - Šála, Michal - Mertlíková-Kaiserová, Helena - Dračínský, Martin - Leyssen, P. - Neyts, J. - Nencka, Radim
    Synthesis of novel thienonorbornylpurine derivatives.
    Tetrahedron. Roč. 68, č. 15 (2012), s. 3195-3204. ISSN 0040-4020. E-ISSN 1464-5416
    R&D Projects: GA ČR GAP303/11/1297; GA MŠMT 1M0508
    Institutional research plan: CEZ:AV0Z40550506
    Keywords : hepatitis virus * Coxsackie virus * sulfur heterocycles
    Subject RIV: CC - Organic Chemistry
    Impact factor: 2.803, year: 2012
    Permanent Link: http://hdl.handle.net/11104/0208925
     
     
  8. 8.
    0376440 - ÚOCHB 2013 RIV GB eng J - Journal Article
    Šála, Michal - Hřebabecký, Hubert - Leyssen, P. - Dejmek, Milan - Dračínský, Martin - De Palma, A. M. - Neyts, J. - Nencka, Radim
    Novel substituted 9-norbornylpurines and their activities against RNA viruses.
    Bioorganic and Medicinal Chemistry Letters. Roč. 22, č. 5 (2012), s. 1963-1968. ISSN 0960-894X. E-ISSN 1464-3405
    R&D Projects: GA ČR GAP303/11/1297; GA MŠMT 1M0508
    Grant - others:FP7 SILVER(XE) 260644
    Institutional research plan: CEZ:AV0Z40550506
    Keywords : antiviral * coxsackievirus * norbornane * picornaviruses * purine
    Subject RIV: CC - Organic Chemistry
    Impact factor: 2.338, year: 2012
    Permanent Link: http://hdl.handle.net/11104/0208836
     
     
  9. 9.
    0376064 - ÚOCHB 2013 RIV GB eng J - Journal Article
    Hřebabecký, Hubert - Dejmek, Milan - Dračínský, Martin - Šála, Michal - Leyssen, P. - Neyts, J. - Kaniaková, Martina - Krůšek, Jan - Nencka, Radim
    Synthesis of novel azanorbornylpurine derivatives.
    Tetrahedron. Roč. 68, č. 4 (2012), s. 1286-1298. ISSN 0040-4020. E-ISSN 1464-5416
    R&D Projects: GA MŠMT 1M0508; GA ČR(CZ) GA202/09/0806; GA MŠMT(CZ) LC554
    Institutional research plan: CEZ:AV0Z40550506; CEZ:AV0Z50110509
    Keywords : azanorbornane * purines * coxsackievirus
    Subject RIV: CC - Organic Chemistry
    Impact factor: 2.803, year: 2012
    Permanent Link: http://hdl.handle.net/11104/0208565
     
     
  10. 10.
    0369985 - ÚOCHB 2013 RIV CZ eng J - Journal Article
    Dejmek, Milan - Hřebabecký, Hubert - Dračínský, Martin - Neyts, J. - Leyssen, P. - Mertlíková-Kaiserová, Helena - Nencka, Radim
    Conformationally locked nucleoside analogues based on the bridgehead substituted 7-oxonorbornane and their antiviral properties.
    Collection of Czechoslovak Chemical Communications. Roč. 76, č. 12 (2011), s. 1549-1566. ISSN 0010-0765
    R&D Projects: GA MŠMT 1M0508
    Institutional research plan: CEZ:AV0Z40550506
    Keywords : 1'-homonucleosides * Diels-Alder reaction * antiviral agents
    Subject RIV: CC - Organic Chemistry
    Impact factor: 1.283, year: 2011
    Permanent Link: http://hdl.handle.net/11104/0203913
     
     

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