Search results
- 1.0443963 - ÚOCHB 2016 RIV CZ eng J - Journal Article
Potměšil, P. - Holý, Antonín - Zídek, Zdeněk
Influence of Acyclic Nucleoside Phosphonate Antivirals on Gene Expression of Chemokine Receptors CCR5 and CXCR4.
Folia Biologica. Roč. 61, č. 1 (2015), s. 1-7. ISSN 0015-5500. E-ISSN 0015-5500
R&D Projects: GA ČR GA305/03/1470; GA MŠMT 1M0508
Institutional support: RVO:61388963 ; RVO:68378041
Keywords : acyclic nucleoside phosphonate * HIV * CCR5 * CXCR4 * cytokine * RT-PCR
Subject RIV: CC - Organic Chemistry; FR - Pharmacology ; Medidal Chemistry (UEM-P)
Impact factor: 0.833, year: 2015
Permanent Link: http://hdl.handle.net/11104/0246598 - 2.0173812 - UEM-P 20033138 RIV US eng J - Journal Article
Botros, S. - William, S. - Hammam, O. - Zídek, Zdeněk - Holý, Antonín
Activity of 9-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]adenine against Schistosomiasis mansoni in mice.
Antimicrobial Agents and Chemotherapy. Roč. 47, č. 12 (2003), s. 3853-3858. ISSN 0066-4804. E-ISSN 1098-6596
R&D Projects: GA ČR GA305/00/0048; GA ČR GA305/03/1470
Institutional research plan: CEZ:AV0Z5008914; CEZ:AV0Z5039906
Keywords : schistosoma mansoni
Subject RIV: FH - Neurology
Impact factor: 4.246, year: 2003
Permanent Link: http://hdl.handle.net/11104/0070838 - 3.0107508 - UEM-P 20043105 RIV NL eng J - Journal Article
Zídek, Zdeněk - Kmoníčková, Eva - Holý, Antonín
Involvement of adenosine A1 receptors in upregulation of nitric oxide by acyclic nucleotide analogues.
[Účast adenosinových A1 receptorů při zvýšení oxidu dusnatého acyklickými analogy nukleotidů.]
European Journal of Pharmacology. Roč. 501, - (2004), s. 79-86. ISSN 0014-2999. E-ISSN 1879-0712
R&D Projects: GA ČR GA305/03/1470; GA AV ČR IBS4055109
Institutional research plan: CEZ:AV0Z5008914; CEZ:AV0Z4055905
Keywords : acyclic nucleoside phosphonate
Subject RIV: FR - Pharmacology ; Medidal Chemistry
Impact factor: 2.432, year: 2004
Permanent Link: http://hdl.handle.net/11104/0014665 - 4.0043838 - ÚEM 2007 RIV NL eng J - Journal Article
Kmoníčková, Eva - Potměšil, Petr - Holý, Antonín - Zídek, Zdeněk
Purine P1 receptor-dependent immunostimulatory effects of antiviral acyclic analogues of adenine and 2,6-diaminopurine.
[Závislost imunostimulačních účinků protivirových acyklických analogů adeninu a 2,6-diaminopurinu na purinových P1 receptorech.]
European Journal of Pharmacology. Roč. 530, - (2006), s. 179-187. ISSN 0014-2999. E-ISSN 1879-0712
R&D Projects: GA ČR GA305/03/1470; GA AV ČR 1QS400550501
Institutional research plan: CEZ:AV0Z50390512; CEZ:AV0Z4055905
Keywords : Acyclic nucleoside phosphonate * Cytokine * Chemokine
Subject RIV: FR - Pharmacology ; Medidal Chemistry
Impact factor: 2.522, year: 2006
Permanent Link: http://hdl.handle.net/11104/0136739 - 5.0043826 - ÚEM 2007 RIV CZ eng J - Journal Article
Kmoníčková, Eva - Kutinová-Canová, N. - Farghali, H. - Holý, Antonín
Modulator of intracellular Ca2+, thapsigargin, interferes with in vitro secretion of cytokines and nitric oxide.
[Modulátor intracelulárního Ca2+, thapsigargin, interferuje s in vitro sekrecí cytokinů a oxidu dusnatého.]
Biomedical Papers. Roč. 149, č. 2 (2006), s. 321-324. ISSN 1213-8118. E-ISSN 1804-7521
R&D Projects: GA ČR GA305/05/2425; GA ČR GA305/03/1470; GA MŠMT 1M0508
Institutional research plan: CEZ:AV0Z50390512; CEZ:AV0Z40550506
Keywords : Thapsigargin * IL-10 * Rantes
Subject RIV: FR - Pharmacology ; Medidal Chemistry
Permanent Link: http://hdl.handle.net/11104/0136728 - 6.0043783 - ÚEM 2007 RIV NL eng J - Journal Article
Potměšil, Petr - Krečmerová, Marcela - Kmoníčková, Eva - Holý, Antonín - Zídek, Zdeněk
Nucleotide analogues with immunobiological properties: 9-[2-hydroxy-3-(phosphonomethoxy)propyl]adenine (HPMPA), -2,6-diaminopurine (HPMPDAP), and their N6-substituted derivatives.
[Analogy nukleotidů s imunobiologickými vlastnostmi: 9-[2-hydroxy-3-(fosfonometoxy)propyl]adenin (HPMPA), -2,6-diaminopurin (HPMPDAP), a jejich N6-substituované deriváty.]
European Journal of Pharmacology. Roč. 540, - (2006), s. 191-199. ISSN 0014-2999. E-ISSN 1879-0712
R&D Projects: GA ČR GA305/03/1470; GA MŠMT 1M0508
Institutional research plan: CEZ:AV0Z50390512; CEZ:AV0Z40550506
Keywords : Acyclic nucleotide analogues * HPMPA 9-[2-hydroxy-3-(phosphonomethoxy)propyl]adenine
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 2.522, year: 2006
Permanent Link: http://hdl.handle.net/11104/0136690 - 7.0021697 - ÚOCHB 2006 RIV GB eng J - Journal Article
Doláková, Petra - Holý, Antonín - Zídek, Zdeněk - Masojídková, Milena - Kmoníčková, Eva
Synthesis and immunobiological activity of base substituted 2-amino-3-(purin-9-yl)propanoic acid derivatives.
[Syntéza a immunobiologická aktivita substituovaných derivátů 2-amino-3-(purin-9-yl)propanové kyseliny.]
Bioorganic & Medicinal Chemistry. Roč. 13, č. 7 (2005), s. 2349-2354. ISSN 0968-0896. E-ISSN 1464-3391
R&D Projects: GA AV ČR(CZ) IBS4055109; GA ČR(CZ) GA305/03/1470
Grant - others:amFAR(US) 106456-34-RGNT; EC René Descartes Prize(XE) HPAW-2002-100096
Institutional research plan: CEZ:AV0Z40550506; CEZ:AV0Z5008914
Keywords : purine * acyclic nucleoside * immunobiological activity
Subject RIV: CC - Organic Chemistry
Impact factor: 2.286, year: 2005
Permanent Link: http://hdl.handle.net/11104/0110618 - 8.0021684 - ÚOCHB 2006 RIV GB eng J - Journal Article
Česnek, Michal - Holý, Antonín - Masojídková, Milena - Zídek, Zdeněk
Synthesis of 9-alkyl and 9-heteroalkyl substituted 2-amino-6-guanidinopurines and their influence on the NO-production in macrophages.
[Syntéza 9-alkyl a 9-heteroalkyl substituovaných 2-amino-6-guanidinopurinů a jejich vliv na produkci NO v makrofágách.]
Bioorganic & Medicinal Chemistry. Roč. 13, č. 8 (2005), s. 2917-2926. ISSN 0968-0896. E-ISSN 1464-3391
R&D Projects: GA AV ČR(CZ) IBS4055109; GA ČR(CZ) GA305/03/1470; GA MŠMT(CZ) OC D13.20
Grant - others:AmFAR(US) 106456-34-RGNT
Institutional research plan: CEZ:AV0Z4055905; CEZ:AV0Z5008914
Keywords : 6-guanidinopurines * guanidino derivatives * immunomodulatory activity
Subject RIV: CC - Organic Chemistry
Impact factor: 2.286, year: 2005
Permanent Link: http://hdl.handle.net/11104/0110607