Search results
- 1.0127207 - BFU-R 20033296 RIV US eng J - Journal Article
Prokop, Radim - Kašpárková, Jana - Nováková, Olga - Marini, Victoria - Pizarro, A. M. - Navarro-Ranninger, C. - Brabec, Viktor
DNA interacions of new antitumor platinum complexes with trans geometry activated by a 2-metylbutylamine of sec-butylamine ligand.
Biochemical Pharmacology. Roč. 67, č. 6 (2004), s. 1097-1109. ISSN 0006-2952. E-ISSN 1873-2968
R&D Projects: GA ČR GA305/02/1552; GA AV ČR KJB5004301; GA AV ČR IBS5004107
Institutional research plan: CEZ:AV0Z5004920
Keywords : cisplatin * transplatin * antitumor drugs
Subject RIV: BO - Biophysics
Impact factor: 3.436, year: 2004
Permanent Link: http://hdl.handle.net/11104/0025428 - 2.0126971 - BFU-R 20033054 RIV US eng J - Journal Article
Kašpárková, Jana - Nováková, Olga - Marini, Victoria - Najajreh, Y. - Gibson, D. - Perez, J.M. - Brabec, Viktor
Activation of trans geometry in bifunctional mononuclear platinum complexes by a piperidine ligand.
Journal of Biological Chemistry. Roč. 278, č. 48 (2003), s. 47516-47525. ISSN 0021-9258. E-ISSN 1083-351X
R&D Projects: GA ČR GA305/02/1552; GA AV ČR KJB5004301
Institutional research plan: CEZ:AV0Z5004920
Keywords : DNA * bifunctional mononuclear platinum complexes * piperidine ligand
Subject RIV: BO - Biophysics
Impact factor: 6.482, year: 2003
Permanent Link: http://hdl.handle.net/11104/0025197 - 3.0126968 - BFU-R 20033049 RIV US eng J - Journal Article
Kašpárková, Jana - Nováková, Olga - Najajreh, Y. - Gibson, D. - Perez, J.M. - Brabec, Viktor
Effects of a piperidine ligand on DNA modification by antitumor cisplatin analogues.
Chemical Research in Toxicology. Roč. 16, č. 11 (2003), s. 1424-1432. ISSN 0893-228X. E-ISSN 1520-5010
R&D Projects: GA ČR GA305/02/1552; GA AV ČR KJB5004301; GA AV ČR IBS5004009
Institutional research plan: CEZ:AV0Z5004920
Keywords : DNA * piperidine ligand * antitumor cisplatin analogues
Subject RIV: BO - Biophysics
Impact factor: 3.332, year: 2003
Permanent Link: http://hdl.handle.net/11104/0025195 - 4.0126967 - BFU-R 20033048 RIV US eng J - Journal Article
Kašpárková, Jana - Marini, Victoria - Najajreh, Y. - Gibson, D. - Brabec, Viktor
DNA binding mode of the cis and trans geometries of new antitumor nonclassical platinum complexes containing piperidine, piperazine or 4-picoline ligand in cell-free media. Relations to their activity in cancer cell lines.
Biochemistry. Roč. 42, č. 20 (2003), s. 6321-6332. ISSN 0006-2960
R&D Projects: GA AV ČR IAA5004101; GA AV ČR KJB5004301; GA ČR GA305/01/0418
Institutional research plan: CEZ:AV0Z5004920
Keywords : cross links * DNA * nonclassical platinum complexes
Subject RIV: BO - Biophysics
Impact factor: 3.922, year: 2003
Permanent Link: http://hdl.handle.net/11104/0025194 - 5.0126966 - BFU-R 20033047 RIV US eng J - Journal Article
Kašpárková, Jana - Mackay, F. S. - Brabec, Viktor - Sadler, P. J.
Formation of platinated GG cross-links on DNA by photoactivation of a Pt(IV) azide complex.
Journal of Biological Inorganic Chemistry. Roč. 8, č. 7 (2003), s. 741-745. ISSN 0949-8257. E-ISSN 1432-1327
R&D Projects: GA AV ČR IAA5004101; GA AV ČR KJB5004301
Institutional research plan: CEZ:AV0Z5004920
Keywords : cross-links * DNA * guanine
Subject RIV: BO - Biophysics
Impact factor: 3.905, year: 2003
Permanent Link: http://hdl.handle.net/11104/0025193 - 6.0104641 - BFU-R 20043023 RIV US eng J - Journal Article
Kašpárková, Jana - Vrána, Oldřich - Farrell, N. - Brabec, Viktor
Effect of the geometry of the central coordination sphere in antitumor trinuclear platinum complexes on DNA binding.
[Vliv geometrie centrální koordinační sféry protinádorově účinných trojjaderných komplexů platiny na jejich vazbu k DNA.]
Journal of Inorganic Biochemistry. Roč. 98, č. 10 (2004), s. 1560-1569. ISSN 0162-0134. E-ISSN 1873-3344.
[International Symposium on Platinum Compounds in Cancer Chemotherapy /9./. New York, 08.10.2004-11.10.2004]
R&D Projects: GA ČR GA305/02/1552; GA AV ČR KJB5004301; GA AV ČR IBS5004009
Grant - others:National Institutes of Health(US) CA-78754
Institutional research plan: CEZ:AV0Z5004920
Keywords : DNA * platinum * antitumor
Subject RIV: BO - Biophysics
Impact factor: 2.225, year: 2004
Permanent Link: http://hdl.handle.net/11104/0011907 - 7.0104638 - BFU-R 20043020 RIV GB eng J - Journal Article
Kašpárková, Jana - Fojta, Miroslav - Farrell, N. - Brabec, Viktor
Differential recognition by the tumor suppressor protein p53 of DNA modified by the novel antitumor trinuclear platinum drug BBR3464 and cisplatin.
[Odlišné rozlišení DNA modifikované novým protinádorově účinným trojjaderným komplexem platiny BBR3464 a cisplatinou nádorově supresorovým proteinem p53.]
Nucleic Acids Research. Roč. 32, č. 18 (2004), s. 5546-5552. ISSN 0305-1048. E-ISSN 1362-4962
R&D Projects: GA AV ČR IAA5004101; GA AV ČR KJB5004301; GA AV ČR IBS5004009; GA ČR GA204/02/0734; GA AV ČR KSK4055109
Grant - others:National Institutes of Health(US) CA-78754
Institutional research plan: CEZ:AV0Z5004920
Keywords : DNA * platinum * p53
Subject RIV: BO - Biophysics
Impact factor: 7.260, year: 2004
Permanent Link: http://hdl.handle.net/11104/0011904 - 8.0104629 - BFU-R 20043011 RIV US eng J - Journal Article
Prokop, Radim - Kašpárková, Jana - Nováková, Olga - Marini, Victoria - Pizarro, A. M. - Navarro-Ranninger, C. - Brabec, Viktor
DNA interacions of new antitumor platinum complexes with trans geometry activated by a 2-metylbutylamine or sec-butylamine ligand.
[Interakce DNA s novými protinádorově účinnými komplexy platiny s geometrií trans kativovanou 2-metylbutylaminem nebo sec-butylamine ligandem.]
Biochemical Pharmacology. Roč. 67, č. 6 (2004), s. 1097-1109. ISSN 0006-2952. E-ISSN 1873-2968
R&D Projects: GA ČR GA305/02/1552; GA AV ČR KJB5004301; GA AV ČR IBS5004107
Grant - others:Ministry of Science and Technology(ES) SAF00-0029; CICYT(ES) SAF 03-01700
Institutional research plan: CEZ:AV0Z5004920
Keywords : cisplatin * transplatin * antitumor drugs
Subject RIV: BO - Biophysics
Impact factor: 3.436, year: 2004
Permanent Link: http://hdl.handle.net/11104/0011895 - 9.0079041 - BFÚ 2007 RIV US eng J - Journal Article
Nováková, Olga - Kašpárková, Jana - Bursová, Vendula - Hofr, Ctirad - Vojtíšková, Marie - Chen, H. - Sadler, P.J. - Brabec, Viktor
Conformation of DNA modified by monofunctional (Ru(II) arene complexes: Recognition by DNA binding proteins and repair. Relationship to cytotoxicity.
[Konformace DNA modifikované monofunkčními RU(II) arénovými komplexy: rozpoznání proteiny vážícími se na DNA a reparace. Vztah k cytotoxicitě.]
Chemistry & Biology. Roč. 12, č. 1 (2006), s. 121-129. ISSN 1074-5521
R&D Projects: GA ČR(CZ) GA305/02/1552; GA AV ČR(CZ) KJB5004301; GA MŠMT OC D20.003
Institutional research plan: CEZ:AV0Z50040507
Keywords : ruthenium * DNA interactions * cytotoxicity
Subject RIV: BO - Biophysics
Impact factor: 6.677, year: 2006
Permanent Link: http://hdl.handle.net/11104/0143937 - 10.0032356 - BFÚ 2006 RIV GB eng J - Journal Article
Nováková, Olga - Kašpárková, Jana - Malina, Jaroslav - Natile, G. - Brabec, Viktor
DNA-protein cross-linking by trans-[PtCl2(E-iminoetherú2]. A concept for activation of the trans geometry in platinum antitumor complexes.
[Tvorba mustků mezi DNA a proteiny komplexem trans-[PtCl2(E-iminoether)].]
Nucleic Acids Research. Roč. 31, č. 22 (2003), s. 6450-6460. ISSN 0305-1048. E-ISSN 1362-4962
R&D Projects: GA MŠMT(CZ) OC D20.004; GA MŠMT(CZ) OC D21.001; GA ČR(CZ) GA305/02/1552; GA AV ČR(CZ) KJB5004301
Institutional research plan: CEZ:AV0Z5004920
Keywords : antitumor drug * DNA * protein
Subject RIV: BO - Biophysics
Impact factor: 6.575, year: 2003
Permanent Link: http://hdl.handle.net/11104/0132893