Search results
- 1.0108444 - BFU-R 20043157 DE eng A - Abstract
Marini, Victoria - Christofis, P. - Farrell, N. - Brabec, Viktor
DNA cross-links of trans-Pt[Cl2(NH3)(thiazole)]. Conformation and recognition by HMG-domain proteins.
COST D20 Conference: Book of Abstracts. Garmisch-Partenkirchen: European Science Foundation, 2004. s. 34-.
[Metal Compounds in the Treatment of Cancer and Viral Diseases (COST D20 Conference). 27.08.2004-28.08.2004, GarmischůPartenkirchen]
R&D Projects: GA ČR GA305/02/1552; GA AV ČR KJB5004301
Keywords : antitumor drugs * cisplatin * transplatin analogue
Subject RIV: BO - Biophysics
Permanent Link: http://hdl.handle.net/11104/0015573 - 2.0104716 - BFU-R 20043098 DE eng A - Abstract
Kašpárková, Jana - Brabec, Viktor
DNA-binding properties of cis-Pt[(NH3)(adamantylamine)Cl2], a metabolite of novel platinum anticancer drug.
COST D20 Conference: Book of Abstracts. Garmisch-Partenkirchen: European Science Foundation, 2004. L-1.
[Metal Compounds in the Treatment of Cancer and Viral Diseases (COST D20 Conference). 27.08.2004-28.08.2004, GarmischůPartenkirchen]
R&D Projects: GA ČR GA305/02/1552; GA AV ČR KJB5004301; GA AV ČR IBS5004107
Keywords : platinum drugs * DNA interaction * anticancer
Subject RIV: BO - Biophysics
Permanent Link: http://hdl.handle.net/11104/0011982 - 3.0104710 - BFU-R 20043092 GB eng A - Abstract
Kašpárková, Jana - Mackay, F. S. - Nováková, Olga - Brabec, Viktor - Sadler, P. J.
Formation of cross-links on DNA by photoactivation of a platinum(IV) azide complex.
European Journal of Biochemistry. Roč. 271, Suppl. 1 (2004), s. 7. ISSN 0014-2956.
[Meeting of the Federation of the European Biochemical Societies /29./. 26.06.2004-01.07.2004, Warsaw]
R&D Projects: GA AV ČR KJB5004301
Keywords : DNA * antitumor * platinum drugs
Subject RIV: BO - Biophysics
Permanent Link: http://hdl.handle.net/11104/0011976 - 4.0022863 - BFÚ 2006 RIV CZ eng A - Abstract
Kašpárková, Jana - Farrell, N. - Brabec, Viktor
Reduced afinity of tumor suppressor protein p53 to DNA modified by antitumor platinum drugs correlates with their antitumor efficacy.
[Snížená afinita nádorového supresoru p53 k DNA modifikované protinádorově účinnými platinovými sloučeninami koreluje s jejich protinádorovou účinností.]
Journal of Applied Biomedicine. Roč. 3, č. 1 (2005), S24. ISSN 1214-021X. E-ISSN 1214-0287.
[Cells VI - Biological Days /18./. 24.10.2005-26.10.2005, České Budějovice]
R&D Projects: GA MZd(CZ) NR8562; GA AV ČR(CZ) KJB5004301
Institutional research plan: CEZ:AV0Z50040507
Keywords : protein p53 * cisplatin
Subject RIV: BO - Biophysics
Permanent Link: http://hdl.handle.net/11104/0111572 - 5.0021989 - BFÚ 2006 IT eng A - Abstract
Nováková, Olga - Kašpárková, Jana - Bursová, Vendula - Hofr, Ctirad - Vojtíšková, Marie - Chen, Haimei - Sadler, Peter J. - Brabec, Viktor
Conformation of DNA modified by monofunctional Ru(II) arene complexes: Recognition by DNA binding proteins and repair. Relationship to cytotoxicity.
[Konformace DNA modifikované monofunkčními Ru(II) arénovými komplexy: Rozpoznání DNA-vazebnými proteiny a oprava. Vztah k cytotoxicitě.]
Book of Abstracts. Rimini, 2005. s. 185.
[European Conference on Chemistry for Life Sciences /1./. 04.10.2005-08.10.2005, Rimini]
R&D Projects: GA ČR(CZ) GA305/02/1552; GA AV ČR(CZ) KJB5004301
Institutional research plan: CEZ:AV0Z50040507
Keywords : antitumor Ru complexes * translesions synthesis * DNA repair
Subject RIV: BO - Biophysics
Permanent Link: http://hdl.handle.net/11104/0110817 - 6.0020977 - BFÚ 2006 IL eng A - Abstract
Kašpárková, Jana - Fojta, Miroslav - Farrell, N. - Brabec, Viktor
Differential recognition by the tumor suppressor protein p53 of DNA modified by the novel antitumor trinuclear platinum drug BBR3464 and cisplatin.
Book of abstracts. Jerusalem, 2005. s. 25.
[Biochemistry, structural and cellular biology of non-classical antitumor platinum compounds (COST working group D20/0003). 17.04.2005-18.04.2005, Jerusalem]
R&D Projects: GA AV ČR(CZ) KJB5004301; GA MZd NR8562
Institutional research plan: CEZ:AV0Z50040507
Keywords : protein p53 * platinum * BBR3464
Subject RIV: BO - Biophysics
Permanent Link: http://hdl.handle.net/11104/0110015 - 7.0001115 - BFÚ 2006 CZ cze A - Abstract
Kašpárková, Jana - Delalande, Olivier - Vojtíšková, Marie - Kozelka, J. - Brabec, Viktor
Rozlišení DNA obsahující meziřetězcový můstek cisplatiny proteinem HMGB1.
[Recognition of DNA interstrand cross-link of antitumor cisplatin by HMGB1 protein.]
Sborník abstrakt XXVIII. Dnů lékařské biofyziky. Brno: Masarykova univerzita v Brně, 2005 - (Vlk, D.; Mornstein, V.). s. 40-40. ISBN 80-210-3695-8.
[Dny lékařské biofyziky /28./. 25.05.2005-27.05.2005, Valtice]
R&D Projects: GA AV ČR(CZ) KJB5004301; GA MZd(CZ) NR8562
Keywords : DNA * platinum * cisplatin
Subject RIV: BO - Biophysics
Permanent Link: http://hdl.handle.net/11104/0018292 - 8.0001114 - BFÚ 2006 CZ cze A - Abstract
Heringová, Pavla - Kašpárková, Jana - Sadler, P. J. - Brabec, Viktor
Světlocitlivé komplexy platiny: nový přístup k vývoji cytostatik.
[Photosensitive platinum complexes: new approach of cytostatic´s development.]
Sborník abstrakt XXVIII. Dnů lékařské biofyziky. Brno: Masarykova univerzita v Brně, 2005 - (Vlk, D.; Mornstein, V.). s. 26-26. ISBN 80-210-3695-8.
[Dny lékařské biofyziky /28./. 25.05.2005-27.05.2005, Valtice]
R&D Projects: GA ČR(CZ) GD204/03/H016; GA AV ČR(CZ) KJB5004301; GA MZd(CZ) NR8562
Keywords : cisplatina * DNA * photosensitive complex
Subject RIV: BO - Biophysics
Permanent Link: http://hdl.handle.net/11104/0018291