Search results
- 1.0557410 - BC 2023 RIV GB eng J - Journal Article
Holoubek, Jiří - Bednářová, Klára - Haviernik, Jan - Huvarová, I. - Dvořáková, Zuzana - Černý, J. - Outlá, Martina - Salát, Jiří - Konkoľová, Eva - Bouřa, Evžen - Růžek, Daniel - Vorlíčková, Michaela - Eyer, Luděk - Renčiuk, Daniel
Guanine quadruplexes in the RNA genome of the tick-borne encephalitis virus: their role as a new antiviral target and in virus biology.
Nucleic Acids Research. Roč. 50, č. 8 (2022), s. 4574-4600. ISSN 0305-1048. E-ISSN 1362-4962
R&D Projects: GA ČR(CZ) GA20-20229S; GA MŠMT EF15_003/0000477
Institutional support: RVO:60077344 ; RVO:68081707 ; RVO:61388963
Keywords : intercalator displacement assay * forming sequences * small-molecule * binding * dna * fluorescence * zika * identification * pyridostatin * inactivation
OECD category: Biochemistry and molecular biology; Biochemistry and molecular biology (BFU-R); Biochemistry and molecular biology (UOCHB-X)
Impact factor: 14.9, year: 2022
Method of publishing: Open access
https://academic.oup.com/nar/article/50/8/4574/6568495?login=true
Permanent Link: https://hdl.handle.net/11104/0339132 - 2.0557061 - BTÚ 2023 RIV CH eng J - Journal Article
Kumar, S. - El-Kafrawy, S. - Bharadwaj, Shiv - Maitra, S. - Alandijany, T. - Faizo, A. - Khateb, A. - Dwivedi, V. - Azhar, E.
Discovery of Bispecific Lead Compounds from Azadirachta indica against ZIKA NS2B-NS3 Protease and NS5 RNA Dependent RNA Polymerase Using Molecular Simulations.
Molecules. Roč. 27, č. 8 (2022), č. článku 2562. E-ISSN 1420-3049
Institutional support: RVO:86652036
Keywords : Zika virus * NS2B-NS3 protease * NS5 RdRp * therapeutics
OECD category: Biochemistry and molecular biology
Impact factor: 4.6, year: 2022
Method of publishing: Open access
https://www.mdpi.com/1420-3049/27/8/2562
Permanent Link: http://hdl.handle.net/11104/0331290 - 3.0554894 - BFÚ 2022 RIV FR eng J - Journal Article
Bohalova, Natalia - Cantara, Alessio - Bartas, M. - Kaura, P. - Šťastný, J. - Pečinka, P. - Fojta, Miroslav - Mergny, Jean-Louis - Brázda, Václav
Analyses of viral genomes for G-quadruplex forming sequences reveal their correlation with the type of infection.
Biochimie. Roč. 186, JUL 2021 (2021), s. 13-27. ISSN 0300-9084. E-ISSN 1638-6183
R&D Projects: GA ČR(CZ) GA18-15548S; GA MŠMT EF15_003/0000477
Institutional support: RVO:68081707
Keywords : rna * replication * promoter * viruses * binding * zika * G-quadruplex
OECD category: Biochemistry and molecular biology
Impact factor: 4.372, year: 2021
Method of publishing: Open access
https://www.sciencedirect.com/science/article/pii/S0300908421000961?via%3Dihub
Permanent Link: http://hdl.handle.net/11104/0329513 - 4.0540544 - BC 2021 RIV CH eng J - Journal Article
Štefánik, M. - Valdés, James J. - Ezebuo, F.C. - Haviernik, J. - Uzochukwu, I.C. - Fojtiková, M. - Salát, J. - Eyer, Luděk - Růžek, Daniel
FDA-Approved Drugs Efavirenz, Tipranavir, and Dasabuvir Inhibit Replication of Multiple Flaviviruses in Vero Cells.
Microorganisms. Roč. 8, č. 4 (2020), č. článku 599. E-ISSN 2076-2607
R&D Projects: GA MZd(CZ) NV16-34238A
Institutional support: RVO:60077344
Keywords : nucleoside inhibitors * virus * protein * screen * pele * fda * flavivirus * Zika virus * tick-borne encephalitis virus * West Nile virus * antiviral
OECD category: Microbiology
Impact factor: 4.128, year: 2020
Method of publishing: Open access
https://www.mdpi.com/2076-2607/8/4/599
Permanent Link: http://hdl.handle.net/11104/0318171 - 5.0519417 - BC 2020 RIV US eng J - Journal Article
Eyer, Luděk - Nougairede, A. - Uhlířová, M. - Driouich, J.-S. - Zouharová, D. - Valdés, James J. - Haviernik, J. - Gould, E. A. - De Clercq, E. - de Lamballerie, X. - Růžek, Daniel
An E460D Substitution in the NS5 Protein of Tick-Borne Encephalitis Virus Confers Resistance to the Inhibitor Galidesivir (BCX4430) and Also Attenuates the Virus for Mice.
Journal of Virology. Roč. 93, č. 16 (2019), č. článku e00367-19. ISSN 0022-538X. E-ISSN 1098-5514
R&D Projects: GA MZd(CZ) NV16-34238A
Institutional support: RVO:60077344
Keywords : zika virus * nucleoside analog * polymerase * culture * fever * dna * bcx4430 * galidesivir * attenuation * drug resistance * mutation * tick-borne encephalitis virus
OECD category: Microbiology
Impact factor: 4.501, year: 2019
Method of publishing: Open access
https://jvi.asm.org/content/jvi/early/2019/05/23/JVI.00367-19.full.pdf
Permanent Link: http://hdl.handle.net/11104/0304389 - 6.0517405 - ÚOCHB 2020 RIV FR eng J - Journal Article
Majerová, Taťána - Novotný, Pavel - Krýsová, Eliška - Konvalinka, Jan
Exploiting the unique features of Zika and Dengue proteases for inhibitor design.
Biochimie. Roč. 166, Nov (2019), s. 132-141. ISSN 0300-9084. E-ISSN 1638-6183
R&D Projects: GA MŠMT LO1302
Institutional support: RVO:61388963
Keywords : active-site inhibitors * allosteric inhibitors * aptamers * precursor * Dengue protease * Zika protease
OECD category: Biochemistry and molecular biology
Impact factor: 3.413, year: 2019
Method of publishing: Limited access
https://www.sciencedirect.com/science/article/abs/pii/S0300908419301439?via%3Dihub
Permanent Link: http://hdl.handle.net/11104/0302990 - 7.0511116 - BC 2020 RIV US eng J - Journal Article
Eyer, Luděk - Fojtiková, M. - Nencka, Radim - Rudolf, Ivo - Hubálek, Zdeněk - Růžek, Daniel
Viral RNA-Dependent RNA Polymerase Inhibitor 7-Deaza-2 '-C-Methyladenosine Prevents Death in a Mouse Model of West Nile Virus Infection.
Antimicrobial Agents and Chemotherapy. Roč. 63, č. 3 (2019), č. článku e02093-18. ISSN 0066-4804. E-ISSN 1098-6596
R&D Projects: GA ČR(CZ) GA16-20054S
Institutional support: RVO:60077344 ; RVO:68081766 ; RVO:61388963
Keywords : adenosine nucleoside inhibitor * hepatitis-c * tick-borne * dengue virus * uridine phosphorylase * antiviral activity * zika virus * new-york * replication * encephalitis * West Nile virus * antiviral agents * flavivirus * nucleoside analogs
OECD category: Microbiology; Microbiology (UBO-W); Virology (UOCHB-X)
Impact factor: 4.904, year: 2019
Method of publishing: Open access
https://aac.asm.org/content/aac/63/3/e02093-18.full.pdf
Permanent Link: http://hdl.handle.net/11104/0301436 - 8.0498814 - BC 2019 RIV GB eng J - Journal Article
Štefánik, M. - Formanová, P. - Bílý, Tomáš - Vancová, Marie - Eyer, Luděk - Palus, Martin - Salát, J. - Braconi, C. T. - Zanotto, P. M. de A. - Gould, E. A. - Růžek, Daniel
Characterisation of Zika virus infection in primary human astrocytes.
BMC Neuroscience. Roč. 19, č. 1 (2018), č. článku 5. ISSN 1471-2202. E-ISSN 1471-2202
R&D Projects: GA MŠMT(CZ) LM2015062; GA TA ČR(CZ) TE01020118
Institutional support: RVO:60077344
Keywords : Astrocyte * Electron tomography * Flavivirus * Immune response * Luminex * Zika virus
OECD category: Microbiology
Impact factor: 2.620, year: 2018
https://bmcneurosci.biomedcentral.com/articles/10.1186/s12868-018-0407-2
Permanent Link: http://hdl.handle.net/11104/0291090 - 9.0498599 - BC 2019 RIV GB eng J - Journal Article
Füzik, T. - Formanová, P. - Růžek, Daniel - Yoshii, K. - Niedrig, M. - Plevka, P.
Structure of tick-borne encephalitis virus and its neutralization by a monoclonal antibody.
Nature Communications. Roč. 9, JAN 30 (2018), č. článku 436. E-ISSN 2041-1723
Institutional support: RVO:60077344
Keywords : west-nile-virus * dengue virus * membrane-fusion * envelope glycoprotein * electron-microscopy * zika virus * cell entry * acidic ph * maturation * proteins
OECD category: Virology
Impact factor: 11.878, year: 2018
https://www.nature.com/articles/s41467-018-02882-0
Permanent Link: http://hdl.handle.net/11104/0290922 - 10.0468233 - BC 2017 RIV US eng J - Journal Article
Fernando, S. - Fernando, T. - Štefánik, M. - Eyer, Luděk - Růžek, Daniel
An Approach for Zika Virus Inhibition Using Homology Structure of the Envelope Protein.
Molecular Biotechnology. Roč. 58, č. 12 (2016), s. 801-806. ISSN 1073-6085. E-ISSN 1559-0305
Institutional support: RVO:60077344
Keywords : Zika virus * homology model * druggability * drug discovery
Subject RIV: EE - Microbiology, Virology
Impact factor: 1.634, year: 2016
Permanent Link: http://hdl.handle.net/11104/0266074