Search results

  1. 1.
    0578776 - ÚMG 2024 RIV DE eng J - Journal Article
    Burocziová, Monika - Daněk, Petr - Oravetzová, Anna - Chalupová, Zuzana - Alberich-Jorda, Meritxell - Macůrek, Libor
    Ppm1d truncating mutations promote the development of genotoxic stress-induced AML.
    Leukemia. Roč. 37, Sep (2023), s. 2209-2220. ISSN 0887-6924. E-ISSN 1476-5551
    R&D Projects: GA ČR GA20-11931S; GA MŠMT LX22NPO5102; GA MŠMT(CZ) LM2018129; GA MŠMT(CZ) EF18_046/0016045
    Institutional support: RVO:68378050
    Keywords : cell self-renewal * stem-cell * phosphatase wip1 * p53 * cycle * hematopoiesis * tumorigenesis * quiescence * maturation * proteins
    OECD category: Biochemistry and molecular biology
    Impact factor: 11.4, year: 2022
    Method of publishing: Open access
    https://www.nature.com/articles/s41375-023-02030-8
    Permanent Link: https://hdl.handle.net/11104/0347691
    FileDownloadSizeCommentaryVersionAccess
    Buroziova_2023.pdf12.4 MBPublisher’s postprintopen-access
     
     
  2. 2.
    0578357 - ÚMG 2025 RIV US eng J - Journal Article
    Martiníková, Andra Stefania - Stoyanov, Miroslav - Oravetzová, Anna - Kok, Y. P. - Yu, S. - Dobrovolná, Jana - Janščák, Pavel - van Vugt, M. - Macůrek, Libor
    PPM1D activity promotes the replication stress caused by cyclin E1 overexpression.
    Molecular Oncology. Roč. 18, č. 1 (2024), s. 6-20. ISSN 1574-7891. E-ISSN 1878-0261
    R&D Projects: GA MŠMT LX22NPO5102; GA MŠMT(CZ) LM2018129; GA ČR GX21-22593X; GA MŠMT(CZ) EF18_046/0016045
    Institutional support: RVO:68378050
    Keywords : dna-damage response * wip1 phosphatase * p53 * cancer * mutations * barrier * tumorigenesis * instability * inhibition * chromatin * cancer * cell cycle * cyclin E1 * PPM1D phosphatase * replication stress
    OECD category: Biochemistry and molecular biology
    Impact factor: 6.6, year: 2022
    Method of publishing: Open access
    https://febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13433
    Permanent Link: https://hdl.handle.net/11104/0349661
     
     
  3. 3.
    0533406 - FGÚ 2021 RIV IE eng J - Journal Article
    Balounová, Kateřina - Soták, Matúš - Ergang, Peter - Vodička, Martin - Vagnerová, Karla - Pácha, Jiří
    Effects of aging and tumorigenesis on coupling between the circadian clock and cell cycle in colonic mucosa.
    Mechanisms of Ageing and Development. Roč. 190, Sep (2020), č. článku 111317. ISSN 0047-6374. E-ISSN 1872-6216
    R&D Projects: GA ČR(CZ) GA13-08304S
    Institutional support: RVO:67985823
    Keywords : cell cycle * aging * tumorigenesis * circadian rhythms * colon
    OECD category: Physiology (including cytology)
    Impact factor: 5.432, year: 2020
    Method of publishing: Limited access
    https://doi.org/10.1016/j.mad.2020.111317
    Permanent Link: http://hdl.handle.net/11104/0311796
     
     
  4. 4.
    0522732 - ÚMG 2020 RIV CH eng J - Journal Article
    Šťastná, Monika - Janečková, Lucie - Hrčkulák, Dušan - Kříž, Vítězslav - Kořínek, Vladimír
    Human Colorectal Cancer from the Perspective of Mouse Models.
    Genes. Roč. 10, č. 10 (2019), č. článku 788. E-ISSN 2073-4425
    R&D Projects: GA ČR(CZ) GA18-26324S; GA MŠMT LO1419
    Institutional support: RVO:68378050
    Keywords : carcinoma * consensus molecular subtypes * intestine * oncogenes * signaling cascades * tumor suppressors * tumorigenesis
    OECD category: Biochemistry and molecular biology
    Impact factor: 3.759, year: 2019
    Method of publishing: Open access
    https://www.mdpi.com/2073-4425/10/10/788
    Permanent Link: http://hdl.handle.net/11104/0307178
     
     
  5. 5.
    0520680 - ÚMG 2020 RIV GB eng J - Journal Article
    Burocziová, Monika - Burdová, Kamila - Martiníková, Andra Stefania - Kašpárek, Petr - Kleiblová, P. - Danielsen, S.A. - Borecka, M. - Jeníková, Gabriela - Janečková, Lucie - Pavel, Jozef - Zemankova, P. - Schneiderová, M. - Schwarzová, L. - Tichá, I. - Sun, X.-F. - Jirásková, Kateřina - Liška, V. - Vodičková, Ludmila - Vodička, Pavel - Sedláček, Radislav - Kleibl, Z. - Lothe, R. A. - Kořínek, Vladimír - Macůrek, Libor
    Truncated PPM1D impairs stem cell response to genotoxic stress and promotes growth of APC-deficient tumors in the mouse colon.
    Cell Death & Disease. Roč. 10, č. 11 (2019), č. článku 818. ISSN 2041-4889. E-ISSN 2041-4889
    R&D Projects: GA ČR GA16-19437S; GA ČR(CZ) GA18-09709S; GA MŠMT 7F14061; GA MŠMT(CZ) LM2015040; GA MŠMT(CZ) ED1.1.00/02.0109; GA MŠMT ED2.1.00/19.0395
    Institutional support: RVO:68378050 ; RVO:68378041
    Keywords : dna-damage response * multiple intestinal neoplasia * consensus molecular subtypes * wip1 phosphatase * wip1-dependent regulation * cancer cells * mutations * gene * breast * tumorigenesis
    OECD category: Cell biology; Cell biology (UEM-P)
    Impact factor: 6.304, year: 2019
    Method of publishing: Open access
    https://www.nature.com/articles/s41419-019-2057-4
    Permanent Link: http://hdl.handle.net/11104/0305939
    FileDownloadSizeCommentaryVersionAccess
    Cell_Death_Disease_M_Burocziova_2019.pdf34.3 MBPublisher’s postprintrequire
     
     
  6. 6.
    0520477 - BFÚ 2020 RIV CH eng J - Journal Article
    Machala, M. - Procházková, J. - Hofmanová, Jiřina - Kralikova, L. - Slavík, J. - Tylichová, Zuzana - Ovesna, Petra - Kozubík, Alois - Vondráček, Jan
    Colon Cancer and Perturbations of the Sphingolipid Metabolism.
    International Journal of Molecular Sciences. Roč. 20, č. 23 (2019), č. článku 6051. E-ISSN 1422-0067
    R&D Projects: GA MZd(CZ) NV15-30585A
    Institutional support: RVO:68081707
    Keywords : membrane-associated sialidase * sphingosine kinase 1 * alkaline sphingomyelinase * intestinal tumorigenesis
    OECD category: Biochemistry and molecular biology
    Impact factor: 4.556, year: 2019
    Method of publishing: Open access
    https://www.mdpi.com/1422-0067/20/23/6051/pdf
    Permanent Link: http://hdl.handle.net/11104/0305146
     
     
  7. 7.
    0500434 - ÚMG 2019 RIV CH eng J - Journal Article
    Hrčkulák, Dušan - Janečková, Lucie - Láníková, Lucie - Kříž, Vítězslav - Horázná, Monika - Babošová, Oľga - Vojtěchová, Martina - Galušková, Kateřina - Šloncová, Eva - Kořínek, Vladimír
    Wnt Effector TCF4 Is Dispensable for Wnt Signaling in Human Cancer Cells.
    Genes. Roč. 9, č. 9 (2018), č. článku 439. E-ISSN 2073-4425
    R&D Projects: GA ČR GA15-25100S; GA MŠMT LO1419; GA MŠMT(CZ) LM2015040; GA MŠMT(CZ) LM2015062
    Institutional support: RVO:68378050
    Keywords : colorectal cancer * conditional gene inactivation * epithelium * gut * organoids * tcf7l2 * tumorigenesis * Wnt signaling
    OECD category: Biochemistry and molecular biology
    Impact factor: 3.331, year: 2018
    Permanent Link: http://hdl.handle.net/11104/0292514
    FileDownloadSizeCommentaryVersionAccess
    Genes_D_Hrckulak_2018.pdf12.9 MBPublisher’s postprintrequire
     
     
  8. 8.
    0470415 - BTÚ 2020 RIV CH eng J - Journal Article
    Tomasetti, M. - Amati, M. - Santarelli, L. - Neužil, Jiří
    MicroRNA in Metabolic Re-Programming and Their Role in Tumorigenesis.
    International Journal of Molecular Sciences. Roč. 17, č. 5 (2016), č. článku 754. E-ISSN 1422-0067
    Institutional support: RVO:86652036
    Keywords : miRNAs * tumorigenesis * miR-126 and cancer-stroma environment * metabolic reprogramming
    OECD category: Biochemistry and molecular biology
    Impact factor: 3.226, year: 2016
    Method of publishing: Open access
    https://www.mdpi.com/1422-0067/17/5/754
    Permanent Link: http://hdl.handle.net/11104/0268056
     
     
  9. 9.
    0455817 - ÚMG 2016 RIV US eng J - Journal Article
    Katsetos, C.D. - Reginato, M.J. - Baas, P.W. - D'Agostino, L. - Legido, A. - Tuszynski, J. A. - Dráberová, Eduarda - Dráber, Pavel
    Emerging microtubule targets in glioma therapy.
    Seminars in Pediatric Neurology. Roč. 22, č. 1 (2015), s. 49-72. ISSN 1071-9091. E-ISSN 1558-0776
    R&D Projects: GA MŠMT LH12050; GA MZd NT14467
    Grant - others:GA AV ČR M200521203PIPP; NIH(US) R01 NS028785; Philadelphia Health Education Corporation (PHEC)–St. Christopher’s Hospital for Children Reunified Endowment (C.D.K.)(US) 323256
    Institutional support: RVO:68378050
    Keywords : glioma tumorigenesis * glioblastoma * tubulin * microtubules
    Subject RIV: EB - Genetics ; Molecular Biology
    Impact factor: 1.303, year: 2015
    Permanent Link: http://hdl.handle.net/11104/0256439
     
     
  10. 10.
    0039136 - BFÚ 2007 CZ cze A - Abstract
    Brázdová, Marie - Walter, K. - Dvořák, Jakub - Němcová, Kateřina - Paleček, Emil - Deppert, W.
    Úloha interakce mutantního proteinu p53 s DNA v tumorgenezi.
    [The rolel of mutp53-DNA interaction in tumorigenesis.]
    Sborník příspěvků: X. Pracovní setkání biochemiků a molekulárních biologů. Brno: Masarykova univerzita v Brně, 2006 - (Wimmerová, M.; Beneš, P.). s. 4-4. ISBN 80-210-3942-6.
    [Pracovní setkání biochemiků a molekulárních biologů /10./. 08.02.2006-09.02.2006, Brno]
    R&D Projects: GA MŠMT(CZ) 1K04119; GA ČR(CZ) GP204/06/P369
    Institutional research plan: CEZ:AV0Z50040507
    Keywords : mutant p53 * tumorigenesis * chromatin
    Subject RIV: BO - Biophysics
    Permanent Link: http://hdl.handle.net/11104/0133299
     
     


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