Search results
- 1.0508820 - ÚOCHB 2020 RIV DE eng J - Journal Article
Rimpelová, S. - Jurášek, M. - Peterková, L. - Bejček, J. - Spiwok, V. - Majdl, M. - Jirásko, M. - Buděšínský, Miloš - Harmatha, Juraj - Kmoníčková, Eva - Drašar, P. - Ruml, T.
Archangelolide: A sesquiterpene lactone with immunobiological potential from Laserpitium archangelica.
Beilstein Journal of Organic Chemistry. Roč. 15, Aug 13 (2019), s. 1933-1944. ISSN 1860-5397. E-ISSN 1860-5397
R&D Projects: GA MŠMT(CZ) LO1304
Institutional support: RVO:61388963 ; RVO:68378041
Keywords : anti-inflammatory properties * archangelolide * dansyl fluorescent conjugate * sarco/endoplasmic reticulum calcium ATPase * sesquiterpene lactone * trilobolide analogue
OECD category: Organic chemistry; Pharmacology and pharmacy (UEM-P)
Impact factor: 2.622, year: 2019
Method of publishing: Open access
https://www.beilstein-journals.org/bjoc/articles/15/189
Permanent Link: http://hdl.handle.net/11104/0299630 - 2.0505590 - ÚOCHB 2020 RIV IT eng J - Journal Article
Harmatha, Juraj - Buděšínský, Miloš - Jurášek, M. - Zimmermann, T. - Drašar, P. - Zídek, Zdeněk - Kmoníčková, Eva - Vejvodová, L.
Structural modification of trilobolide for upgrading its immunobiological properties and reducing its cytotoxic action.
Fitoterapia. Roč. 134, Apr (2019), s. 88-95. ISSN 0367-326X. E-ISSN 1873-6971
Institutional support: RVO:61388963 ; RVO:68378041
Keywords : sesquiterpene lactones * trilobolide derivatives * cytotoxicity * nitric oxide production * immunomodulatory activity
OECD category: Organic chemistry; Pharmacology and pharmacy (UEM-P)
Impact factor: 2.527, year: 2019
Method of publishing: Limited access
https://www.sciencedirect.com/science/article/abs/pii/S0367326X18320987?via%3Dihub
Permanent Link: http://hdl.handle.net/11104/0297060 - 3.0476521 - ÚEB 2018 RIV DE eng J - Journal Article
Škorpilová, Ludmila - Rimpelová, S. - Jurášek, M. - Buděšínský, Miloš - Lokajová, Jana - Effenberg, R. - Slepička, P. - Ruml, T. - Kmoníčková, Eva - Drašar, P. B. - Wimmer, Zdeněk
BODIPY-based fluorescent liposomes with sesquiterpene lactone trilobolide.
Beilstein Journal of Organic Chemistry. Roč. 13, JUL 4 (2017), s. 1316-1324. ISSN 1860-5397. E-ISSN 1860-5397
R&D Projects: GA MŠMT LD15012; GA MŠMT(CZ) LO1304
Institutional support: RVO:61389030 ; RVO:61388963 ; RVO:68378041
Keywords : BODIPY conjugates * Cancer targeting * Drug delivery * Liposomes * Natural compounds * Sesquiterpene lactone trilobolide
OECD category: Organic chemistry; Pharmacology and pharmacy (UEM-P)
Impact factor: 2.330, year: 2017
Permanent Link: http://hdl.handle.net/11104/0273002File Download Size Commentary Version Access 2017_Skorpilova_BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY_1316.pdf 7 5.5 MB Other open-access - 4.0474379 - ÚOCHB 2018 RIV US eng J - Journal Article
Huml, L. - Jurášek, M. - Mikšátková, P. - Zimmermann, T. - Tomanová, P. - Buděšínský, Miloš - Rottnerová, Z. - Šimková, M. - Harmatha, Juraj - Kmoníčková, Eva - Lapčík, O. - Drašar, P. B.
Immunoassay for determination of trilobolide.
Steroids. Roč. 117, Jan (2017), s. 105-111. ISSN 0039-128X. E-ISSN 1878-5867.
[Conference on Isoprenoids /23./. Minsk, 04.09.2016-07.09.2016]
Institutional support: RVO:61388963 ; RVO:68378041
Keywords : trilobolide * avidin-biotin * ELISA * Laser trilobum * synthesis * immunoassay
OECD category: Biochemical research methods; Pharmacology and pharmacy (UEM-P)
Impact factor: 2.523, year: 2017
Permanent Link: http://hdl.handle.net/11104/0271443 - 5.0473082 - ÚMG 2017 RIV US eng J - Journal Article
Jurášek, M. - Džubák, P. - Rimpelová, S. - Sedlák, David - Konečný, P. - Frydrych, I. - Gurska, S. - Hajdúch, M. - Bogdanová, K. - Kolář, M. - Muller, Tomáš - Kmoníčková, Eva - Ruml, T. - Harmatha, Juraj - Drašar, P. B.
Trilobolide-steroid hybrids: Synthesis, cytotoxic and antimycobacterial activity.
Steroids. Roč. 117, JAN (2017), s. 97-104. ISSN 0039-128X. E-ISSN 1878-5867
R&D Projects: GA MŠMT(CZ) LO1304; GA MŠMT LO1220; GA MŠMT LM2015063
Grant - others:GA ČR(CZ) GA14-04329S
Institutional support: RVO:68378050 ; RVO:68378041 ; RVO:61388963
Keywords : Trilobolide * Steroids * Click chemistry * Cytotoxicity * sar * Steroid receptor
OECD category: Biochemistry and molecular biology; Organic chemistry (UOCHB-X)
Impact factor: 2.523, year: 2017
Permanent Link: http://hdl.handle.net/11104/0270248 - 6.0455314 - ÚOCHB 2016 RIV IT eng J - Journal Article
Harmatha, Juraj - Vokáč, Karel - Buděšínský, Miloš - Zídek, Zdeněk - Kmoníčková, Eva
Immunobiological properties of sesquiterpene lactones obtained by chemically transformed structural modifications of trilobolide.
Fitoterapia. Roč. 107, Dec (2015), s. 90-99. ISSN 0367-326X. E-ISSN 1873-6971
R&D Projects: GA ČR GA305/07/0061
Institutional support: RVO:61388963 ; RVO:68378041
Keywords : sesquiterpene lactones * guaianolides * trilobolide derivatives * nitric oxide * cytokines * immunoactivity
Subject RIV: CC - Organic Chemistry
Impact factor: 2.408, year: 2015
Permanent Link: http://hdl.handle.net/11104/0255933 - 7.0444157 - ÚOCHB 2016 RIV US eng J - Journal Article
Tomanová, P. - Rimpelová, S. - Jurášek, M. - Buděšínský, Miloš - Vejvodová, L. - Ruml, T. - Kmoníčková, E. - Drašar, P. B.
Trilobolide-porphyrin conjugates: On synthesis and biological effects evaluation.
Steroids. Roč. 97, SI (2015), s. 8-12. ISSN 0039-128X. E-ISSN 1878-5867
Grant - others:GA ČR(CZ) GA14-04329S; GA MŠk(CZ) ED2.1.00/03.0076
Institutional support: RVO:61388963
Keywords : trilobolide * porphyrin * nitric oxide * fluorescence microscopy
Subject RIV: CE - Biochemistry
Impact factor: 2.513, year: 2015
Permanent Link: http://hdl.handle.net/11104/0246762 - 8.0436080 - ÚEM 2015 RIV US eng J - Journal Article
Jurášek, M. - Rimpelová, S. - Kmoníčková, Eva - Drašar, P. - Ruml, T.
Tailor-Made Fluorescent Trilobolide To Study Its Biological Relevance.
Journal of Medicinal Chemistry. Roč. 57, č. 19 (2014), s. 7947-7954. ISSN 0022-2623. E-ISSN 1520-4804
Grant - others:GA ČR(CZ) GA14-28334S; GA MŠMT(CZ) 20/2014
Program: GA
Institutional support: RVO:68378041
Keywords : trilobolide * nitric oxide * endoplasmic reticulum
Subject RIV: FR - Pharmacology ; Medidal Chemistry
Impact factor: 5.447, year: 2014
Permanent Link: http://hdl.handle.net/11104/0239877 - 9.0433789 - ÚOCHB 2015 CZ eng A - Abstract
Kmoníčková, E. - Rimpelová, S. - Vejvodová, L. - Harmatha, Juraj - Zídek, Zdeněk - Ruml, T. - Jurášek, M. - Drašar, P.
Immunomodulatory properties of natural sesquiterpene lactone trilobolide and its conjugates.
Chemické listy. Česká společnost chemická. Roč. 108, S2 (2014), L1. ISSN 0009-2770. E-ISSN 1213-7103.
[Conference on Isoprenoids /22./. 07.09.2014-10.09.2014, Praha]
Grant - others:GA ČR(CZ) GA14-04329S
Institutional support: RVO:61388963 ; RVO:68378041
Keywords : trilobolide * nitric oxide * immunobiological activity
Subject RIV: CC - Organic Chemistry
Permanent Link: http://hdl.handle.net/11104/0238219 - 10.0396383 - ÚOCHB 2014 RIV IT eng J - Journal Article
Harmatha, Juraj - Buděšínský, Miloš - Vokáč, Karel - Kostecká, Petra - Kmoníčková, Eva - Zídek, Zdeněk
Trilobolide and related sesquiterpene lactones from Laser trilobum possessing immunobiological properties.
Fitoterapia. Roč. 89, September (2013), s. 157-166. ISSN 0367-326X. E-ISSN 1873-6971
R&D Projects: GA ČR GA305/07/0061
Institutional support: RVO:61388963 ; RVO:68378041
Keywords : Laser trilobum * nitric oxide * trilobolide * thapsigargin * cytokine * sesquiterpene
Subject RIV: CC - Organic Chemistry; FR - Pharmacology ; Medidal Chemistry (UEM-P)
Impact factor: 2.216, year: 2013
Permanent Link: http://hdl.handle.net/11104/0224219