Search results
- 1.0572295 - ÚMG 2024 RIV CH eng J - Journal Article
Kahveci-Tuerkoez, S. - Blaesius, K. - Wozniak, J. - Rinkens, C. - Seifert, A. - Kašpárek, Petr - Ohm, H. - Oltzen, S. - Nieszporek, M. - Schwarz, N. - Babendreyer, A. - Preisinger, C. - Sedláček, Radislav - Ludwig, A. - Duesterhoeft, S.
A structural model of the iRhom-ADAM17 sheddase complex reveals functional insights into its trafficking and activity.
Cellular and Molecular Life Sciences. Roč. 80, č. 5 (2023), č. článku 135. ISSN 1420-682X. E-ISSN 1420-9071
R&D Projects: GA MŠMT(CZ) LM2018126
Institutional support: RVO:68378050
Keywords : iRhom * adam17 * Ectodomain shedding * TNF signalling * EGFR ligand release iRhom-ADAM17 complex structure * iRhom homology domain
OECD category: Biochemistry and molecular biology
Impact factor: 8, year: 2022
Method of publishing: Open access
https://link.springer.com/article/10.1007/s00018-023-04783-y
Permanent Link: https://hdl.handle.net/11104/0343044 - 2.0571652 - MBÚ 2024 RIV NZ eng J - Journal Article
Jirásková Zákostelská, Zuzana - Reiss, Zuzana - Tlaskalová-Hogenová, Helena - Rob, F.
Paradoxical Reactions to Anti-TNFa and Anti-IL-17 Treatment in Psoriasis Patients: Are Skin and/or Gut Microbiota Involved?
Dermatology and Therapy. Roč. 13, č. 4 (2023), s. 911-933. ISSN 2193-8210. E-ISSN 2190-9172
R&D Projects: GA MZd(CZ) NV18-09-00493; GA MZd(CZ) NU22J-05-00056; GA MZd(CZ) NU22-01-00077
Institutional support: RVO:61388971
Keywords : Skin microbiota * Gut microbiota * Psoriasis * ibd * TNF alpha * il-17 * Biologics * Skin adverse events * Gut-skin axis
OECD category: Immunology
Impact factor: 3.4, year: 2022
Method of publishing: Open access
https://link.springer.com/article/10.1007/s13555-023-00904-4
Permanent Link: https://hdl.handle.net/11104/0342919 - 3.0566813 - MBÚ 2023 RIV CH eng J - Journal Article
Reiss, Zuzana - Rob, F. - Kolář, M. - Schierová, Dagmar - Kreisinger, J. - Jacková, Zuzana - Roubalová, Radka - Coufal, Štěpán - Mihula, Martin - Thon, Tomáš - Bajer, Lukáš - Nováková, M. - Vašátko, M. - Kostovčíková, Klára - Galanová, Natálie - Lukáš, M. - Kverka, Miloslav - Třešňák Hercogová, J. - Tlaskalová-Hogenová, Helena - Jirásková Zákostelská, Zuzana
Skin microbiota signature distinguishes IBD patients and reflects skin adverse events during anti-TNF therapy.
Frontiers in Cellular and Infection Microbiology. Roč. 13, January 10 (2023), č. článku 1064537. ISSN 2235-2988. E-ISSN 2235-2988
R&D Projects: GA MZd(CZ) NV18-09-00493; GA MZd(CZ) NU22J-05-00056; GA ČR(CZ) GA20-03997S
Institutional support: RVO:61388971
Keywords : Skin microbiota * IBD * 16S RNA sequencing * Serum biomarker * TNF-alpha antagonist * Skin adverse events
OECD category: Microbiology
Impact factor: 5.7, year: 2022
Method of publishing: Open access
https://www.frontiersin.org/articles/10.3389/fcimb.2022.1064537/full
Permanent Link: https://hdl.handle.net/11104/0338102 - 4.0556113 - BFÚ 2023 RIV DE eng J - Journal Article
Perečková, Jana - Martiniakova, S. - Payer, J. - Falk, Martin - Killinger, Z. - Perečko, Tomáš
ANALYSIS OF HEMATOLOGICAL PARAMETERS IN RHEUMATOID ARTHRITIS PATIENTS RECEIVING BIOLOGICAL THERAPY: CONTRIBUTION TO PREVENTION OF AVOIDABLE HEMATOLOGICAL COMPLICATIONS.
EXCLI Journal. Roč. 21, č. 2022 (2022), s. 580-594. ISSN 1611-2156. E-ISSN 1611-2156
R&D Projects: GA ČR(CZ) GJ17-08066Y; GA MŠMT(CZ) LTAUSA17160
Institutional support: RVO:68081707
Keywords : tumor-necrosis-factor * factor inhibitors * disease-activity * tnf-alpha * tocilizumab * neutrophil
OECD category: Cardiac and Cardiovascular systems
Impact factor: 4.6, year: 2022
Method of publishing: Limited access
https://www.excli.de/index.php/excli/article/view/4702
Permanent Link: https://hdl.handle.net/11104/0340257 - 5.0544132 - ÚMG 2022 RIV CH eng J - Journal Article
Dusterhoft, S. - Kahveci-Tuerkoez, S. - Wozniak, J. - Seifert, A. - Kašpárek, Petr - Ohm, H. - Liu, S. - Kopkanová, Jana - Lokau, J. - Garbers, C. - Preisinger, C. - Sedláček, Radislav - Freeman, M. - Ludwig, A.
The iRhom homology domain is indispensable for ADAM17-mediated TNF alpha and EGF receptor ligand release.
Cellular and Molecular Life Sciences. Roč. 78, č. 11 (2021), s. 5015-5040. ISSN 1420-682X. E-ISSN 1420-9071
Institutional support: RVO:68378050
Keywords : iRhom * adam17 * Ectodomain shedding * tnf * Growth factors * iRhom homology domain
OECD category: Biochemistry and molecular biology
Impact factor: 9.234, year: 2021
Method of publishing: Open access
https://link.springer.com/article/10.1007/s00018-021-03845-3
Permanent Link: http://hdl.handle.net/11104/0321178 - 6.0539726 - ÚMG 2021 RIV CH eng J - Journal Article
Seifert, A. - Wozniak, J. - Duesterhoeft, S. - Kašpárek, Petr - Sedláček, Radislav - Dreschers, S. - Orlikowsky, T.W. - Yildiz, D. - Ludwig, A.
The iRhom2/ADAM17 Axis Attenuates Bacterial Uptake by Phagocytes in a Cell Autonomous Manner.
International Journal of Molecular Sciences. Roč. 21, č. 17 (2020), č. článku 5978. E-ISSN 1422-0067
R&D Projects: GA MŠMT(CZ) LM2015040; GA MŠMT(CZ) LM2018126; GA MŠMT ED2.1.00/19.0395
Institutional support: RVO:68378050
Keywords : necrosis-factor-alpha * mycobacterium-tuberculosis * adam17 deficiency * tnf-alpha * disintegrin * inflammation * neutrophils * activation * receptor * irhom2 * metalloproteinase * adam17 * iRhom2 * bacterial phagocytosis * inflammation * infection * shedding * chemokines * phagocytes
OECD category: Microbiology
Impact factor: 5.924, year: 2020
Method of publishing: Open access
https://www.mdpi.com/1422-0067/21/17/5978
Permanent Link: http://hdl.handle.net/11104/0317429 - 7.0520648 - ÚMG 2020 RIV CH eng J - Journal Article
Seroussi, E. - Knytl, M. - Pitel, F. - Elleder, Daniel - Krylov, V. - Leroux, S. - Morisson, M. - Yosefi, S. - Miyara, S. - Ganesan, S. - Ruzal, M. - Andersson, L. - Friedman-Einat, M.
Avian Expression Patterns and Genomic Mapping Implicate Leptin in Digestion and TNF in Immunity, Suggesting That Their Interacting Adipokine Role Has Been Acquired Only in Mammals.
International Journal of Molecular Sciences. Roč. 20, č. 18 (2019), č. článku 4489. E-ISSN 1422-0067
R&D Projects: GA MŠMT LO1419
Institutional support: RVO:68378050
Keywords : radiation-hybrid mapping * fish-tsa * chicken * tnf * immune system * leptin * digestive tract * duodenum
OECD category: Immunology
Impact factor: 4.556, year: 2019
Method of publishing: Open access
https://www.mdpi.com/1422-0067/20/18/4489
Permanent Link: http://hdl.handle.net/11104/0306721 - 8.0458741 - ÚOCHB 2017 RIV CH eng J - Journal Article
Acikara, O. B. - Hošek, J. - Babula, P. - Cvačka, Josef - Buděšínský, Miloš - Dračínský, Martin - Iscan, G. S. - Kadlecová, D. - Ballová, L. - Šmejkal, K.
Turkish Scorzonera Species Extracts Attenuate Cytokine Secretion via Inhibition of NF-kappa B Activation, Showing Anti-Inflammatory Effect in Vitro.
Molecules. Roč. 21, č. 1 (2016), č. článku 43. E-ISSN 1420-3049
Institutional support: RVO:61388963
Keywords : anti-inflammatory activity * IL-1 beta * NF-kappa B * Scorzonera * phenolic * TNF-alpha * triterpen
Subject RIV: CC - Organic Chemistry
Impact factor: 2.861, year: 2016
http://www.mdpi.com/1420-3049/21/1/43/htm
Permanent Link: http://hdl.handle.net/11104/0258990 - 9.0442265 - ÚEM 2015 HR eng C - Conference Paper (international conference)
Zídek, Zdeněk - Kmoníčková, Eva - Janeba, Zlatko - Kolman, Viktor - Jansa, Petr
Structure-dependent NO-, PGE2- and cytokine-inhibitory effects of pyrimidine derivatives.
Proceedings of the Joint Meeting of the 8th International Symposium Nitric Oxide. organizátor symposia, 2014, s. 6-10. ISBN 978-80-971699-0-9.
[Proceedings of the Joint Meeting of the 8th International Symposium Nitric Oxide: From Basic Regulations to Lifestyle-Related Diseases and The 2nd Genetic and Environmental Factors in Hypertension [0312302]. Vrsan (HR), 15.09.2014-19.09.2014]
R&D Projects: GA ČR(CZ) GAP303/12/0172
Institutional support: RVO:68378041 ; RVO:61388963
Keywords : PGE2 * TNF-a * pyrimidine derivatives
Subject RIV: FR - Pharmacology ; Medidal Chemistry
Permanent Link: http://hdl.handle.net/11104/0245104 - 10.0392656 - ÚMG 2014 RIV CZ cze L - Prototype, f. module
Stegurová, Lucie - Dráber, Petr
Nano-iPCR pro detekci TNF-α (Nano-iPCR- TNF-α).
[Nano-iPCR for TNF-α detection (Nano-iPCR- TNF-α).]
Internal code: - ; 2012
Technical parameters: Nový amplifikační systém založený na přítomnosti nanopartikule zlata (GNP) fukcionalizované protilátkou specifickou pro TNF-α a jednovláknovým oligonukleotidem. Dosud nebyla uzavřena licenční smlouva. Kontaktní osoba RNDr. Petr Dráber, DrSc., petr.draber@img.cas.cz.
Economic parameters: předáno pro komerční využití firně Top-Bio s.r.o., IČ 64578895
R&D Projects: GA TA ČR TA01010436; GA MPO FR-TI3/067; GA ČR GAP302/10/1759
Institutional support: RVO:68378050
Keywords : Nano-iPCR * GNPs * TNF-α
Subject RIV: EB - Genetics ; Molecular Biology
Permanent Link: http://hdl.handle.net/11104/0221859