Search results
- 1.0583244 - FGÚ 2025 RIV CH eng J - Journal Article
Kysilov, Bohdan - Kuchtiak, Viktor - Hrčka Krausová, Barbora - Balík, Aleš - Kořínek, Miloslav - Fili, Klevinda - Dobrovolski, Mark - Abramová, Vera - Chodounská, Hana - Kudová, Eva - Božíková, Paulina - Černý, Jiří - Smejkalová, Tereza - Vyklický ml., Ladislav
Disease-associated nonsense and frame-shift variants resulting in the truncation of the GluN2A or GluN2B C-terminal domain decrease NMDAR surface expression and reduce potentiating effects of neurosteroids.
Cellular and Molecular Life Sciences. Roč. 81, č. 1 (2024), č. článku 36. ISSN 1420-682X. E-ISSN 1420-9071
R&D Projects: GA ČR(CZ) GA23-04922S; GA TA ČR(CZ) TN02000109; GA MZd(CZ) EF16_025/0007444
Institutional support: RVO:67985823 ; RVO:61388963 ; RVO:86652036
Keywords : glutamate receptors * channelopathy * endogenous neuroactive steroid * GRIN2 genes * surface expression * rescue pharmacology
OECD category: Neurosciences (including psychophysiology
Impact factor: 8, year: 2022
Method of publishing: Open access
https://doi.org/10.1007/s00018-023-05062-6
Permanent Link: https://hdl.handle.net/11104/0351253 - 2.0577525 - ÚOCHB 2024 RIV eng P - Patent Document
Kudová, Eva - Chodounská, Hana - Mareš, Pavel - Valeš, Karel
3α5ß-Neuroactive steroids for the treatment of epilepsy and seizure diseases.
2023. Owner: Ústav organické chemie a biochemie AV ČR, v. v. i. - Fyziologický ústav AV ČR, v. v. i. Date of the patent acceptance: 01.08.2023. Patent Number: CA3128921. Territorial Protection: národní patent v zemi mimo EU ,mezinárodní patentová ochrana dle Smlouvy o patentové spolupráci.
Institutional support: RVO:61388963 ; RVO:67985823
Keywords : pregnanolone * epilepsy * steroid
OECD category: Neurosciences (including psychophysiology
https://worldwide.espacenet.com/patent/search/family/070285346/publication/CA3128921C?q=CA3128921C
Permanent Link: https://hdl.handle.net/11104/0346645 - 3.0575940 - ÚEB 2024 RIV GB eng J - Journal Article
Voňka, Petr - Rárová, L. - Bazgier, V. - Tichý, V. - Kolářová, T. - Holčáková, J. - Berka, K. - Kvasnica, Miroslav - Oklešťková, Jana - Kudová, Eva - Strnad, Miroslav - Hrstka, Roman
Small change – big consequence: The impact of C15-C16 double bond in a D‑ring of estrone on estrogen receptor activity.
Journal of Steroid Biochemistry and Molecular Biology. Roč. 233, OCT (2023), č. článku 106365. ISSN 0960-0760
R&D Projects: GA MŠMT(CZ) LM2023055; GA MŠMT LX22NPO5102
Research Infrastructure: e-INFRA CZ - 90140; BBMRI.cz IV - 90233
Institutional support: RVO:61389030 ; RVO:61388963
Keywords : Apoptosis * Docking of steroid library * Estrogen receptor alpha * Luciferase assay * Mitochondrial membrane potential
OECD category: Biochemistry and molecular biology
Impact factor: 4.1, year: 2022
Method of publishing: Open access
https://doi.org/10.1016/j.jsbmb.2023.106365
Permanent Link: https://hdl.handle.net/11104/0345624File Download Size Commentary Version Access 2023_Vonka_JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY_106365.pdf 3 5.7 MB Other open-access - 4.0573162 - ÚOCHB 2024 RIV cze P - Patent Document
Kudová, Eva - Chodounská, Hana - Mareš, Pavel - Valeš, Karel
3α5ß-Neuroaktivní steroidy pro léčbu epilepsie a záchvatových onemocnění.
[3α5ß-Neuroactive steroids for the treatment of epilepsy and seizure disorders.]
2023. Owner: Ústav organické chemie a biochemie AV ČR, v. v. i. - Fyziologický ústav AV ČR, v. v. i. Date of the patent acceptance: 12.04.2023. Patent Number: 309617. Territorial Protection: národní patent v členském státě EU .
Institutional support: RVO:61388963 ; RVO:67985823
Keywords : pregnanolone * epilepsy * steroid
OECD category: Neurosciences (including psychophysiology
https://isdv.upv.cz/doc/FullFiles/Patents/FullDocuments/309/309617.pdf
Permanent Link: https://hdl.handle.net/11104/0343619 - 5.0573159 - ÚOCHB 2024 RIV jpn P - Patent Document
Kudová, Eva - Chodounská, Hana - Mareš, Pavel - Valeš, Karel
てんかんおよび発作疾患の治療のための3α5β-神経活性ステロイド.
[3α5ß-Neuroactive steroids for the treatment of epilepsy and seizure disorders.]
2023. Owner: Ústav organické chemie a biochemie AV ČR, v. v. i. - Fyziologický ústav AV ČR, v. v. i. Date of the patent acceptance: 29.03.2023. Patent Number: JP7248819. Territorial Protection: národní patent v zemi mimo EU ,mezinárodní patentová ochrana dle Smlouvy o patentové spolupráci.
Institutional support: RVO:61388963 ; RVO:67985823
Keywords : pregnanolone * epilepsy * steroid
OECD category: Neurosciences (including psychophysiology
https://worldwide.espacenet.com/patent/search/family/070285346/publication/JP7248819B2?q=JP7248819
Permanent Link: https://hdl.handle.net/11104/0343617 - 6.0572804 - FGÚ 2024 RIV US eng J - Journal Article
Abramová, Vera - Leal Alvarado, Vanessa - Hill, M. - Smejkalová, Tereza - Malý, Michal - Valeš, Karel - Dittert, Ivan - Božíková, Paulina - Kysilov, Bohdan - Hrčka Krausová, Barbora - Vyklický, Vojtěch - Balík, Aleš - Fili, Klevinda - Kořínek, Miloslav - Chodounská, Hana - Kudová, Eva - Číž, D. - Martinovič, J. - Černý, Jiří - Bartůněk, Petr - Vyklický ml., Ladislav
Effects of Pregnanolone Glutamate and Its Metabolites on GABAA and NMDA Receptors and Zebrafish Behavior.
ACS Chemical Neuroscience. Roč. 14, č. 10 (2023), s. 1870-1883. ISSN 1948-7193. E-ISSN 1948-7193
R&D Projects: GA MZd(CZ) EF16_025/0007444; GA MŠMT LM2023052; GA ČR(CZ) GA23-04922S; GA TA ČR(CZ) TN02000109
Research Infrastructure: CZ-OPENSCREEN IV - 90252
Institutional support: RVO:67985823 ; RVO:86652036 ; RVO:61388963 ; RVO:68378050
Keywords : negative allosteric modulator * thigmotaxis * steroid * glutamate * zebrafish
OECD category: Neurosciences (including psychophysiology; Neurosciences (including psychophysiology (UOCHB-X); Biochemistry and molecular biology (UMG-J); Biochemistry and molecular biology (BTO-N)
Impact factor: 5, year: 2022
Method of publishing: Limited access
https://doi.org/10.1021/acschemneuro.3c00131
Permanent Link: https://hdl.handle.net/11104/0343402 - 7.0566053 - ÚFCH JH 2024 RIV US eng J - Journal Article
Vazquez-Chavez, J. - Martínez-Torres, F. C. - Navarro-Huerta, A. - Flores-Álamo, M. - Maldonado-Domínguez, Mauricio - Blahut, Jan - Štoček, Jakub Radek - Dračínský, Martin - Rodríguez-Molina, B. - Iglesias-Arteaga, M. A.
A Crystalline Dimeric Steroidal Diboronate with Electronically Impeded Rotation.
Journal of Organic Chemistry. Roč. 88, č. 1 (2023), s. 49-59. ISSN 0022-3263. E-ISSN 1520-6904
R&D Projects: GA ČR(CZ) GA20-01472S
Research Infrastructure: e-INFRA CZ - 90140
Institutional support: RVO:61388955 ; RVO:61388963
Keywords : dimeric steroid SMR-3 * NMR data * molecular dynamics
OECD category: Physical chemistry
Impact factor: 3.6, year: 2022
Method of publishing: Limited access
Permanent Link: https://hdl.handle.net/11104/0337490File Download Size Commentary Version Access 0566053preprint.pdf 1 5.4 MB Author´s preprint require - 8.0557651 - MBÚ 2023 RIV NL eng J - Journal Article
Černá, Tereza - Ezechiáš, Martin - Semerád, Jaroslav - Grasserová, Alena - Cajthaml, Tomáš
Evaluation of estrogenic and antiestrogenic activity in sludge and explanation of individual compound contributions.
Journal of Hazardous Materials. Roč. 423, FEB 5 2022 (2022), č. článku 127108. ISSN 0304-3894. E-ISSN 1873-3336
Institutional support: RVO:61388971
Keywords : effect-directed analysis * municipal waste-water * generalized concentration addition * reporter gene assay * sewage-sludge * bisphenol analogs * environmental estrogens * androgenic activity * endocrine activity * steroid estrogens * WWTP sludge * Mixture toxicity * Constructed wetland * Agonistic activity * Antagonistic activity
OECD category: Environmental sciences (social aspects to be 5.7)
Impact factor: 13.6, year: 2022
Method of publishing: Limited access
https://www.sciencedirect.com/science/article/pii/S0304389421020768?via%3Dihub
Permanent Link: http://hdl.handle.net/11104/0331560 - 9.0550825 - MBÚ 2022 RIV CZ eng J - Journal Article
Kolesárová, A. - Michalcová, K. - Roychoudhury, S. - Baldovská, S. - Tvrdá, E. - Vašíček, J. - Chrenek, P. - Sanislo, L. - Křen, Vladimír
Antioxidative Effect of Dietary Flavonoid Isoquercitrin on Human Ovarian Granulosa Cells HGL5 In Vitro.
Physiological Research. Roč. 70, č. 5 (2021), s. 745-754. ISSN 0862-8408. E-ISSN 1802-9973
Institutional support: RVO:61388971
Keywords : Flavonoid * Granulosa cells * Antioxidant * Steroid hormones * Transforming growth factor
OECD category: Pharmacology and pharmacy
Impact factor: 2.139, year: 2021
Method of publishing: Open access
https://www.biomed.cas.cz/physiolres/pdf/2021/70_745.pdf
Permanent Link: http://hdl.handle.net/11104/0326133 - 10.0549377 - ÚFCH JH 2023 RIV DE eng J - Journal Article
Mayorquín-Torres, M. C. - Maldonado-Domínguez, Mauricio - Flores-Álamo, M. - Iglesias-Arteaga, M. A.
Synthesis and Characterization of Hybrid Dimeric Steroid Spiroketals.
Synthesis. Roč. 54, č. 03 (2022), s. 643-654. ISSN 0039-7881. E-ISSN 1437-210X
Research Infrastructure: e-INFRA CZ - 90140
Institutional support: RVO:61388955
Keywords : reduction * Sonogashira coupling * Pd-catalyzed spiroketalization * hybrid steroid dimers * nmr * X-ray diffraction * DFT-NBO calculations
OECD category: Physical chemistry
Impact factor: 2.6, year: 2022
Method of publishing: Limited access
https://www.thieme-connect.de/products/ejournals/abstract/10.1055/a-1647-7610
Permanent Link: http://hdl.handle.net/11104/0325386File Download Size Commentary Version Access 0549377preprint.pdf 2 1.4 MB Author´s preprint open-access