Search results
- 1.0586779 - ÚMG 2025 US eng J - Journal Article
Gbelcova, H. - Rimpelová, S. - Jariabkova, A. - Macasek, P. - Priscakova, P. - Ruml, T. - Šáchová, Jana - Kubovčiak, Jan - Kolář, Michal - Vítek, L.
Highly variable biological effects of statins on cancer, non-cancer, and stem cells in vitro.
Scientific Reports. Roč. 14, č. 1 (2024), č. článku 11830. ISSN 2045-2322. E-ISSN 2045-2322
R&D Projects: GA MŠMT(CZ) EF16_019/0000785
Institutional support: RVO:68378050
Keywords : gene-expression * synchronization * activation * Pancreatic cancer cells * Stem cells * Microarray analysis * Cell spheroids * 3-Hydroxy-3-methylglutaryl coenzyme A inhibitors * Statins
OECD category: Cell biology
Impact factor: 3.8, year: 2023
Method of publishing: Open access
https://www.nature.com/articles/s41598-024-62615-w
Permanent Link: https://hdl.handle.net/11104/0354461 - 2.0555475 - ÚMG 2022 RIV CH eng J - Journal Article
Rimpelová, S. - Kolář, Michal - Strnad, Hynek - Rumlová, T. - Vítek, L. - Gbelcova, H.
Comparison of Transcriptomic Profiles of MiaPaCa-2 Pancreatic Cancer Cells Treated with Different Statins.
Molecules. Roč. 26, č. 12 (2021), č. článku 3528. ISSN 1420-3049. E-ISSN 1420-3049
R&D Projects: GA MŠMT(CZ) EF16_019/0000785
Institutional support: RVO:68378050
Keywords : statins * pancreatic cancer * DNA microarray * pitavastatin * cerivastatin * simvastatin * fluvastatin * atorvastatin * pravastatin * HMG-CoA reductase inhibitors
OECD category: Biochemistry and molecular biology
Impact factor: 4.927, year: 2021
Method of publishing: Open access
https://www.mdpi.com/1420-3049/26/12/3528
Permanent Link: http://hdl.handle.net/11104/0329987 - 3.0486290 - ÚMG 2018 RIV GB eng J - Journal Article
Gbelcová, H. - Rimpelová, S. - Knejzlík, Z. - Šáchová, Jana - Kolář, Michal - Strnad, Hynek - Repiska, V. - D'Acunto, C.W. - Ruml, T. - Vítek, L.
Isoprenoids responsible for protein prenylation modulate the biological effects of statins on pancreatic cancer cells.
Lipids in Health and Disease. Roč. 16, zima (2017), č. článku 250. ISSN 1476-511X. E-ISSN 1476-511X
R&D Projects: GA MZd(CZ) NT13112
Institutional support: RVO:68378050
Keywords : Farmesyl pyrophosphate * Gene expression * Geranylgeranyl pyrophosphate * HMG-CoA reductase inhibitors * Isoprenoids * K-Ras oncogene * Mevalonate * Pncreatic cancer * Prenylation * Statins
OECD category: Cell biology
Impact factor: 2.663, year: 2017
Permanent Link: http://hdl.handle.net/11104/0281151 - 4.0480628 - ÚŽFG 2018 RIV GB eng J - Journal Article
Fafílek, B. - Hampl, Marek - Říčánková, N. - Veselá, Iva - Bálek, L. - Kunová Bosáková, M. - Gudernová, I. - Vařecha, M. - Buchtová, Marcela - Krejčí, P.
Statins do not inhibit the FGFR signaling in chondrocytes.
Osteoarthritis and Cartilage. Roč. 25, č. 9 (2017), s. 1522-1530. ISSN 1063-4584. E-ISSN 1522-9653
R&D Projects: GA ČR(CZ) GA14-31540S
Grant - others:GA MŠk(CZ) LH12004
Institutional support: RVO:67985904
Keywords : statins * FGF signaling * chondrocytes
OECD category: Developmental biology
Impact factor: 5.454, year: 2017
Permanent Link: http://hdl.handle.net/11104/0276360 - 5.0473134 - BTÚ 2017 RIV GB eng J - Journal Article
Váňová, K. - Boukalová, Štěpána - Gbelcová, H. - Muchová, L. - Neužil, Jiří - Gürlich, R. - Ruml, T. - Vítek, L.
Heme oxygenase is not involved in the anti-proliferative effects of statins on pancreatic cancer cells.
BMC Cancer. Roč. 16, May 12 (2016), č. článku 309. ISSN 1471-2407. E-ISSN 1471-2407
R&D Projects: GA MZd NT14078; GA MŠMT(CZ) ED1.1.00/02.0109
Institutional support: RVO:86652036
Keywords : Heme * Heme oxygenase * Pancreatic cancer * Statins
Subject RIV: FD - Oncology ; Hematology
Impact factor: 3.288, year: 2016
Permanent Link: http://hdl.handle.net/11104/0270305 - 6.0458398 - FGÚ 2017 RIV US eng J - Journal Article
Vevera, J. - Valeš, Karel - Fišar, Z. - Hroudová, J. - Singh, N. - Stuchlík, Aleš - Kačer, P. - Nekovářová, Tereza
The effect of prolonged simvastatin application on serotonin uptake, membrane microviscosity and behavioral changes in the animal model.
Physiology and Behavior. Roč. 158, May 1 (2016), s. 112-120. ISSN 0031-9384. E-ISSN 1873-507X
R&D Projects: GA MZd(CZ) NT13403; GA ČR(CZ) GBP304/12/G069; GA ČR(CZ) GAP303/12/1464
Grant - others:Rada Programu interní podpory projektů mezinárodní spolupráce AV ČR(CZ) M200111204
Institutional support: RVO:67985823
Keywords : statins * rats * cholesterol * brain * serotonergic neurotransmission * behavior
Subject RIV: FH - Neurology
Impact factor: 2.341, year: 2016
Permanent Link: http://hdl.handle.net/11104/0258663 - 7.0428031 - FGÚ 2015 RIV CZ eng J - Journal Article
Soukup, Tomáš
Effects of long-term thyroid hormone level alterations, n-3 polyunsaturated fatty acid supplementation and statin administration in rats.
Physiological Research. Roč. 63, Suppl.1 (2014), S119-S131. ISSN 0862-8408. E-ISSN 1802-9973
R&D Projects: GA ČR(CZ) GA304/08/0256; GA ČR(CZ) GA305/09/1228; GA ČR(CZ) GAP304/12/0259; GA MŠMT(CZ) LH12058; GA MŠMT(CZ) 7AMB12SK158; GA MŠMT(CZ) 7AMB14SK123
Grant - others:EC(XE) LSH-CT-2004-511978
Institutional support: RVO:67985823
Keywords : thyroid hormones * n-3 polyunsaturated fatty acids (n-3 PUFA) * statins * rat muscle proteins * cardiac remodeling
Subject RIV: ED - Physiology
Impact factor: 1.293, year: 2014
Permanent Link: http://hdl.handle.net/11104/0233443 - 8.0332172 - FGÚ 2010 RIV DK eng J - Journal Article
Šimko, F. - Pecháňová, Olga
Potential roles of melatonin and chronotherapy among the new trends in hypertension treatment.
[Možná úloha melatoninu a chronoterapie jako nové trendy v léčbě hypertenze.]
Journal of Pineal Research. Roč. 47, č. 2 (2009), s. 127-133. ISSN 0742-3098. E-ISSN 1600-079X
R&D Projects: GA MŠMT(CZ) 1M0510
Institutional research plan: CEZ:AV0Z50110509
Keywords : chrontherapy * aliskiren * statins
Subject RIV: ED - Physiology
Impact factor: 5.209, year: 2009
Permanent Link: http://hdl.handle.net/11104/0177501 - 9.0315973 - ÚOCHB 2009 RIV DE eng J - Journal Article
Gbelcová, H. - Leníček, M. - Zelenka, J. - Knejzlík, Z. - Dvořáková, G. - Zadinová, M. - Poučková, P. - Kudla, M. - Balaž, P. - Ruml, Tomáš - Vítek, L.
Differences in antitumor effects of various statins on human pancreatic cancer.
[Rozdílná antinádorová účinnost statinů na nádor pankreatu.]
International Journal of Cancer. Roč. 122, č. 6 (2008), s. 1214-1221. ISSN 0020-7136. E-ISSN 1097-0215
R&D Projects: GA ČR(CZ) GD204/03/H066
Grant - others:GA MZd(CZ) NR8132
Institutional research plan: CEZ:AV0Z40550506
Keywords : statins * pancreatic cancer * K-ras oncogene
Subject RIV: CE - Biochemistry
Impact factor: 4.734, year: 2008
Permanent Link: http://hdl.handle.net/11104/0166032 - 10.0045387 - ÚEM 2007 RIV IE eng J - Journal Article
Syka, Josef - Ouda, Ladislav - Nachtigal, P. - Solichová, D. - Semecký, V.
Atorvastatin slows down the deterioration of inner ear function with age in mice.
[Atorvastatin zpomaluje s věkem související poškození vnitřního ucha u myši.]
Neuroscience Letters. Roč. 411, č. 2 (2007), s. 112-116. ISSN 0304-3940. E-ISSN 1872-7972
R&D Projects: GA ČR GA309/04/1074; GA MZd NR8113; GA MŠMT LC554; GA ČR GP304/03/P049
Institutional research plan: CEZ:AV0Z50390512
Keywords : Statins * Presbycusis * Distortion product otoacoustic emission
Subject RIV: FH - Neurology
Impact factor: 2.085, year: 2007
Permanent Link: http://hdl.handle.net/11104/0137925