Search results
- 1.0582787 - ÚMG 2025 RIV GB eng J - Journal Article
Tykvartova, T. - Miklovic, M. - Kotrc, M. - Škaroupková, P. - Kazdová, L. - Trnovská, J. - Skop, V. - Kolář, Michal - Novotný, Jiří - Melenovský, V.
The impact of phosphodiesterase-5 inhibition or angiotensin-converting enzyme inhibition on right and left ventricular remodeling in heart failure due to chronic volume overload.
PHARMACOL RES PERSPE. Roč. 12, č. 1 (2024), č. článku e1172. ISSN 2052-1707. E-ISSN 2052-1707
Institutional support: RVO:68378050
Keywords : transgenic hypertensive-rats * soluble epoxide hydrolase * natriuretic-peptide * myocardial-infarction * renal dysfunction * sildenafil * expression * pressure * type-5 * model * heart failure * phosphodiesterase-5 inhibition * rats * right ventricle * volume overload
OECD category: Biochemistry and molecular biology
Impact factor: 2.6, year: 2022
Method of publishing: Open access
https://bpspubs.onlinelibrary.wiley.com/doi/10.1002/prp2.1172
Permanent Link: https://hdl.handle.net/11104/0352873 - 2.0556810 - FGÚ 2023 RIV US eng J - Journal Article
Imig, J. D. - Červenka, L. - Neckář, Jan
Epoxylipids and soluble epoxide hydrolase in heart diseases.
Biochemical Pharmacology. Roč. 195, Jan (2022), č. článku 114866. ISSN 0006-2952. E-ISSN 1873-2968
R&D Projects: GA ČR(CZ) GA18-03207S
Institutional support: RVO:67985823
Keywords : eicosanoids * cytochrome P450 * soluble epoxide hydrolase * hypertension * heart failure * myocardial infarction * inflammation * mitochondrial function * coronary artery
OECD category: Physiology (including cytology)
Impact factor: 5.8, year: 2022
Method of publishing: Limited access
https://doi.org/10.1016/j.bcp.2021.114866
Permanent Link: http://hdl.handle.net/11104/0331112 - 3.0518671 - FGÚ 2020 RIV CH eng J - Journal Article
Čertíková - Chábová, V. - Kujal, P. - Vaňourková, Z. - Škaroupková, P. - Sadowski, J. - Kompanowska - Jezierska, E. - Tesař, V. - Hammock, B. - Imig, J. - Maxová, H. - Červenka, L. - Vaněčková, Ivana
Addition of Endothelin A-Receptor Blockade Spoils the Beneficial Effect of Combined Renin-Angiotensin and Soluble Epoxide Hydrolase Inhibition: Studies on the Course of Chronic Kidney Disease in 5/6 Nephrectomized Ren-2 Transgenic Hypertensive Rats.
Kidney & Blood Pressure Research. Roč. 44, č. 6 (2019), s. 1493-1505. ISSN 1420-4096. E-ISSN 1423-0143
Institutional support: RVO:67985823
Keywords : chronic kidney disease * 5/6 renal mass reduction * hypertension * soluble epoxide hydrolase inhibitor * renin-angiotensin system * endothelin A receptor blocker
OECD category: Cardiac and Cardiovascular systems
Impact factor: 1.898, year: 2019
Method of publishing: Open access
https://doi.org/10.1159/000504137
Permanent Link: http://hdl.handle.net/11104/0303752 - 4.0504092 - FGÚ 2020 RIV CH eng J - Journal Article
Hrdlička, Jaroslav - Neckář, Jan - Papoušek, František - Husková, Z. - Kikerlová, S. - Vaňourková, Z. - Vernerová, Z. - Akat, Firat - Vašinová, Jana - Hammock, B.D. - Hwang, S.H. - Imig, J. D. - Falck, J. R. - Červenka, L. - Kolář, František
Epoxyeicosatrienoic Acid-Based Therapy Attenuates the Progression of Postischemic Heart Failure in Normotensive Sprague-Dawley but Not in Hypertensive Ren-2 Transgenic Rats.
Frontiers in Pharmacology. Roč. 10, Mar 1 (2019), č. článku 159. ISSN 1663-9812. E-ISSN 1663-9812
R&D Projects: GA MZd(CZ) NV15-27735A
Institutional support: RVO:67985823
Keywords : epoxyeicosatrienoic acid * soluble epoxide hydrolase * chronic heart failure * hypertension * myocardial infarction * echocardiography
OECD category: Physiology (including cytology)
Impact factor: 4.225, year: 2019
Method of publishing: Open access
https://doi.org/10.3389/fphar.2019.00159
Permanent Link: http://hdl.handle.net/11104/0295795 - 5.0489812 - FGÚ 2019 RIV GB eng J - Journal Article
Červenka, L. - Husková, Z. - Kopkan, L. - Kikerlová, S. - Sedláková, L. - Vaňourková, Z. - Alánová, Petra - Kolář, František - Hammock, B.D. - Hwang, S.H. - Imig, J. D. - Falck, J. R. - Sadowski, J. - Kompanowska - Jezierska, E. - Neckář, Jan
Two pharmacological epoxyeicosatrienoic acid-enhancing therapies are effectively antihypertensive and reduce the severity of ischemic arrhythmias in rats with angiotensin II-dependent hypertension.
Journal of Hypertension. Roč. 36, č. 6 (2018), s. 1326-1341. ISSN 0263-6352. E-ISSN 1473-5598
R&D Projects: GA ČR(CZ) GA15-07544S
Institutional support: RVO:67985823
Keywords : epoxyeicosatrienoic acid analogue * epoxyeicosatrienoic acid * infarct size * ischemic arrhythmia * kidney * renin–angiotensin system * soluble epoxide hydrolase inhibitor
OECD category: Physiology (including cytology)
Impact factor: 4.209, year: 2018
Permanent Link: http://hdl.handle.net/11104/0284155 - 6.0377329 - FGÚ 2013 RIV GB eng J - Journal Article
Neckář, Jan - Kopkan, L. - Husková, Z. - Kolář, František - Papoušek, František - Kramer, H. J. - Hwang, S.H. - Hammock, B.D. - Imig, J. D. - Malý, J. - Netuka, I. - Ošťádal, Bohuslav - Červenka, L.
Inhibition of soluble epoxide hydrolase by cis-4-[4-(3-adamantan-1-ylureido)cyclohexyl-oxy]benzoic acid exhibits antihypertensive and cardioprotective actions in transgenic rats with angiotensin II-dependent hypertension.
Clinical science. Roč. 122, č. 11 (2012), s. 513-525. ISSN 0143-5221. E-ISSN 1470-8736
R&D Projects: GA AV ČR(CZ) IAAX01110901; GA AV ČR(CZ) KAN200520703; GA MŠMT(CZ) 1M0510
Institutional research plan: CEZ:AV0Z50110509
Keywords : hypertension * angiotensin II * kidney * epoxyeicosatrienoic acids * soluble epoxide hydrolase inhibitor * myocardial ischemia/reperfusion injury
Subject RIV: FA - Cardiovascular Diseases incl. Cardiotharic Surgery
Impact factor: 4.859, year: 2012
Permanent Link: http://hdl.handle.net/11104/0209513 - 7.0365126 - FGÚ 2012 GB eng J - Journal Article
Čertíková - Chábová, V. - Walkowska, A. - Kompanowska - Jezierska, E. - Sadowski, J. - Kujal, P. - Vernerová, Z. - Vaňourková, Z. - Kopkan, L. - Kramer, H. J. - Falck, J. R. - Imig, J. D. - Hammock, B.D. - Vaněčková, Ivana - Červenka, L.
Combined inhibition of 20-hydroxyeicosatetraenoic acid formation and of epoxyeicosatrienoic acids degradation attenuates hypertension and hypertensioninduced end-organ damage in Ren-2 transgenic rats.
Clinical science. Roč. 118, č. 10 (2010), s. 617-632. ISSN 0143-5221. E-ISSN 1470-8736
Grant - others:GA ČR(CZ) GA305/07/0167; GA ČR(CZ) GC305/07/J004
Institutional research plan: CEZ:AV0Z50110509
Keywords : cytochrome P-450 metabolites * renin-angiotensin system * hypertension * end-organ damage * soluble epoxide hydrolase
Subject RIV: FA - Cardiovascular Diseases incl. Cardiotharic Surgery
Impact factor: 4.613, year: 2010
Permanent Link: http://hdl.handle.net/11104/0200441