Search results
- 1.0555475 - ÚMG 2022 RIV CH eng J - Journal Article
Rimpelová, S. - Kolář, Michal - Strnad, Hynek - Rumlová, T. - Vítek, L. - Gbelcova, H.
Comparison of Transcriptomic Profiles of MiaPaCa-2 Pancreatic Cancer Cells Treated with Different Statins.
Molecules. Roč. 26, č. 12 (2021), č. článku 3528. E-ISSN 1420-3049
R&D Projects: GA MŠMT(CZ) EF16_019/0000785
Institutional support: RVO:68378050
Keywords : statins * pancreatic cancer * DNA microarray * pitavastatin * cerivastatin * simvastatin * fluvastatin * atorvastatin * pravastatin * HMG-CoA reductase inhibitors
OECD category: Biochemistry and molecular biology
Impact factor: 4.927, year: 2021
Method of publishing: Open access
https://www.mdpi.com/1420-3049/26/12/3528
Permanent Link: http://hdl.handle.net/11104/0329987 - 2.0486292 - ÚMG 2018 RIV GB eng J - Journal Article
Gbelcová, H. - Rimpelová, S. - Ruml, T. - Fenclova, M. - Kosek, V. - Hajslova, J. - Strnad, Hynek - Kolář, Michal - Vítek, L.
Variability in statin-induced changes in gene expression profiles of pancreatic cancer.
Scientific Reports. Roč. 7, jaro (2017), č. článku 44219. ISSN 2045-2322. E-ISSN 2045-2322
R&D Projects: GA MŠMT(CZ) LO1304
Institutional support: RVO:68378050
Keywords : hmg-coa reductase * lipid droplets * rho-gtpases * cell-death * in-vitro * risk * protein * association * simvastatin * apoptosis
OECD category: Pharmacology and pharmacy
Impact factor: 4.122, year: 2017
Permanent Link: http://hdl.handle.net/11104/0281153 - 3.0439661 - ÚMCH 2015 RIV GB eng J - Journal Article
Urbanová, Martina - Šturcová, Adriana - Kredatusová, Jana - Brus, Jiří
Structural insight into the physical stability of amorphous Simvastatin dispersed in pHPMA: enhanced dynamics and local clustering as evidenced by solid-state NMR and Raman spectroscopy.
International Journal of Pharmaceutics. Roč. 478, č. 2 (2015), s. 464-475. ISSN 0378-5173. E-ISSN 1873-3476
R&D Projects: GA ČR(CZ) GA14-03636S; GA MŠMT(CZ) LD14010
Grant - others:European Commission(XE) COST Action MP1202 HINT
Institutional support: RVO:61389013
Keywords : solid dispersions * simvastatin * pharmaceuticals
Subject RIV: CD - Macromolecular Chemistry
Impact factor: 3.994, year: 2015
Permanent Link: http://hdl.handle.net/11104/0245027 - 4.0425127 - FGÚ 2014 GB eng J - Journal Article
Gbelcová, H. - Sveda, M. - Laubertová, L. - Varga, I. - Vítek, L. - Kolář, M. - Strnad, H. - Zelenka, Jaroslav - Boehmer, D. - Ruml, T.
The effect of simvastatin on lipid droplets accumulation in human embryonic kidney cells and pancreatic cancer cells.
Lipids in Health and Disease. Roč. 12, AUG 21 (2013), s. 126. E-ISSN 1476-511X
Institutional support: RVO:67985823
Keywords : simvastatin * lipid droplets * DNA microarray
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 2.310, year: 2013
Permanent Link: http://hdl.handle.net/11104/0231056 - 5.0422934 - ÚMG 2014 RIV GB eng J - Journal Article
Gbelcová, H. - Sveda, M. - Laubertová, L. - Varga, I. - Vítek, L. - Kolář, Michal - Strnad, Hynek - Zelenka, J. - Boehmer, D. - Ruml, T.
The effect of simvastatin on lipid droplets accumulation in human embryonic kidney cells and pancreatic cancer cells.
Lipids in Health and Disease. Roč. 12, 21.8.2013 (2013), s. 126. E-ISSN 1476-511X
R&D Projects: GA MZd(CZ) NT13112
Grant - others:GA MŠk(CZ) EE2.3.30.0060
Program: EE
Institutional support: RVO:68378050
Keywords : simvastatin * lipid droplets * DNA microarray * Nile red * pancreatic cancer
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 2.310, year: 2013
Permanent Link: http://hdl.handle.net/11104/0229171 - 6.0394464 - ÚMCH 2014 CZ eng A - Abstract
Urbanová, Martina - Kredatusová, Jana - Šturcová, Adriana - Policianová, Olivia - Zhigunov, Alexander - Brus, Jiří
Structural analysis of solid dispersion of simvastatin.
19th European Symposium on Polymer Spectroscopy - ESOPS19. 77th Prague Meeting on Macromolecules. Prague: Institute of Macromolecular Chemistry AS CR, v. v. i, 2013. s. 112. ISBN 978-80-85009-77-4.
[European Symposium on Polymer Spectroscopy /19./ - ESOPS19. Prague Meeting on Macromolecules /77./. 07.07.2013-11.07.2013, Prague]
R&D Projects: GA ČR GPP106/11/P426
Institutional support: RVO:61389013
Keywords : simvastatin * structural analysis
Subject RIV: FR - Pharmacology ; Medidal Chemistry
Permanent Link: http://hdl.handle.net/11104/0222773 - 7.0385630 - ÚMCH 2013 CZ eng A - Abstract
Brus, Jiří - Urbanová, Martina - Policianová, Olivia - Husak, M.
NMR crystallography - structure refinement (simvastatin).
Program a abstrakta. Praha: Ústav makromolekulární chemie AV ČR, v. v. i, 2012. s. 14.
[Workshop on Solid-State NMR and Computational Methods /6./. 04.12.2012, Praha]
Institutional support: RVO:61389013
Keywords : NMR * simvastatin
Subject RIV: CD - Macromolecular Chemistry
Permanent Link: http://hdl.handle.net/11104/0216052 - 8.0370014 - ÚOCHB 2012 CZ eng A - Abstract
Mandlíková, J. - Volková, M. - Nový, Z. - Pávek, P. - Janeba, Zlatko - Trejtnar, F.
In vitro study of potential of selected drugs to interact with antivirals on human organic anion transporter 1.
61. Farmakologické dny a Ephar Symposium. Brno: -, 2011. -.
[Farmakologické dny a Ephar Symposium /61./. 14.09.2011-16.09.2011, Brno]
Institutional research plan: CEZ:AV0Z40550506
Keywords : human organic anion transporter (hOAT1) * antivirals * adefovir * entecavir * simvastatin
Subject RIV: CC - Organic Chemistry
Permanent Link: http://hdl.handle.net/11104/0203936 - 9.0343202 - ÚMCH 2011 RIV US eng J - Journal Article
Hušák, M. - Kratochvíl, B. - Jegorov, A. - Brus, Jiří - Maixner, J. - Rohlíček, J.
Simvastatin: structure solution of two new low-temperature phases from synchrotron powder diffraction and ss-NMR.
Structural Chemistry. Roč. 21, č. 3 (2010), s. 511-518. ISSN 1040-0400. E-ISSN 1572-9001
R&D Projects: GA AV ČR IAA400500602; GA MŠMT 2B08021
Institutional research plan: CEZ:AV0Z40500505
Keywords : crystal structure * simvastatin * powder diffraction
Subject RIV: CD - Macromolecular Chemistry
Impact factor: 1.727, year: 2010
Permanent Link: http://hdl.handle.net/11104/0005900 - 10.0321245 - FGÚ 2009 RIV CZ eng J - Journal Article
Szárszoi, Ondrej - Malý, J. - Ošťádal, P. - Netuka, I. - Bešík, J. - Kolář, František - Ošťádal, Bohuslav
Effect of acute and chronic simvastatin treatment on post-ischemic contractile dysfunction in isolated rat heart.
[Vliv akutního a chronického podání simvastatinu na post-ischemickou kontraktilní dysfunkci isolovaného srdce potkana.]
Physiological Research. Roč. 57, č. 5 (2008), s. 793-796. ISSN 0862-8408. E-ISSN 1802-9973
R&D Projects: GA MŠMT(CZ) 1M0510
Institutional research plan: CEZ:AV0Z50110509
Keywords : simvastatin * contractile dysfunction * protection
Subject RIV: FA - Cardiovascular Diseases incl. Cardiotharic Surgery
Impact factor: 1.653, year: 2008
Permanent Link: http://hdl.handle.net/11104/0169864