Search results

  1. 1.
    0557947 - ÚOCHB 2023 RIV AE eng J - Journal Article
    Selvaraj, C. - Dinesh, Dhurvas Chandrasekaran - Krafčíková, Petra - Bouřa, Evžen - Aarthy, M. - Pravin, M. A. - Singh, S. K.
    Structural Understanding of SARS-CoV-2 Drug Targets, Active Site Contour Map Analysis and COVID-19 Therapeutics.
    Current Molecular Pharmacology. Roč. 15, č. 2 (2022), s. 418-433. ISSN 1874-4672. E-ISSN 1874-4702
    R&D Projects: GA MŠMT(CZ) EF16_019/0000729
    Institutional support: RVO:61388963
    Keywords : SARS-CoV-2 * COVID-19 * repurposing * FDA * drug targets * antivirales * active site * contour maps * medicinal plants * phytochemicals * TCM * natural products
    OECD category: Virology
    Impact factor: 2.7, year: 2022
    Method of publishing: Limited access
    https://doi.org/10.2174/1874467214666210906125959
    Permanent Link: http://hdl.handle.net/11104/0331831
     
     
  2. 2.
    0545100 - ÚMCH 2022 RIV CH eng J - Journal Article
    Studenovský, Martin - Rumlerová, Anna - Kostka, Libor - Etrych, Tomáš
    HPMA-based polymer conjugates for repurposed drug mebendazole and other imidazole-based therapeutics.
    Polymers. Roč. 13, č. 15 (2021), č. článku 2530. E-ISSN 2073-4360
    R&D Projects: GA ČR(CZ) GA19-01417S; GA ČR(CZ) GA19-05649S; GA MŠMT(CZ) LTAUSA18083
    Institutional support: RVO:61389013
    Keywords : mebendazole * drug delivery * drug repurposing
    OECD category: Polymer science
    Impact factor: 4.967, year: 2021
    Method of publishing: Open access
    https://www.mdpi.com/2073-4360/13/15/2530
    Permanent Link: http://hdl.handle.net/11104/0321902
     
     
  3. 3.
    0542558 - ÚOCHB 2022 RIV CH eng J - Journal Article
    Terrier, O. - Dilly, S. - Pizzorno, A. - Chalupská, Dominika - Humpolíčková, Jana - Bouřa, Evžen - Berenbaum, F. - Quideau, S. - Lina, B. - Fève, B. - Adnet, F. - Sabbah, M. - Rosa-Calatrava, M. - Maréchal, V. - Henri, J. - Slama-Schwok, A.
    Antiviral Properties of the NSAID Drug Naproxen Targeting the Nucleoprotein of SARS-CoV-2 Coronavirus.
    Molecules. Roč. 26, č. 9 (2021), č. článku 2593. E-ISSN 1420-3049
    Institutional support: RVO:61388963
    Keywords : antiviral * drug repurposing * SARS-CoV-2 * influenza * structure-based drug design * inflammation * nucleoprotein * oligomerization
    OECD category: Biochemistry and molecular biology
    Impact factor: 4.927, year: 2021
    Method of publishing: Open access
    https://doi.org/10.3390/molecules26092593
    Permanent Link: http://hdl.handle.net/11104/0319945
     
     
  4. 4.
    0522796 - ÚMG 2020 RIV CH eng J - Journal Article
    Mrkvova, Z. - Uldrijan, S. - Pombinho, António R. - Bartůněk, Petr - Slaninová, I.
    Benzimidazoles Downregulate Mdm2 and MdmX and Activate p53 in MdmX Overexpressing Tumor Cells.
    Molecules. Roč. 24, č. 11 (2019), č. článku 2152. E-ISSN 1420-3049
    Institutional support: RVO:68378050
    Keywords : benzimidazoles * drug repurposing * Mdm2 * MdmX * melanoma * p53
    OECD category: Biochemistry and molecular biology
    Impact factor: 3.267, year: 2019
    Method of publishing: Open access
    https://www.mdpi.com/1420-3049/24/11/2152
    Permanent Link: http://hdl.handle.net/11104/0307228
     
     


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