Search results
- 1.0557947 - ÚOCHB 2023 RIV AE eng J - Journal Article
Selvaraj, C. - Dinesh, Dhurvas Chandrasekaran - Krafčíková, Petra - Bouřa, Evžen - Aarthy, M. - Pravin, M. A. - Singh, S. K.
Structural Understanding of SARS-CoV-2 Drug Targets, Active Site Contour Map Analysis and COVID-19 Therapeutics.
Current Molecular Pharmacology. Roč. 15, č. 2 (2022), s. 418-433. ISSN 1874-4672. E-ISSN 1874-4702
R&D Projects: GA MŠMT(CZ) EF16_019/0000729
Institutional support: RVO:61388963
Keywords : SARS-CoV-2 * COVID-19 * repurposing * FDA * drug targets * antivirales * active site * contour maps * medicinal plants * phytochemicals * TCM * natural products
OECD category: Virology
Impact factor: 2.7, year: 2022
Method of publishing: Limited access
https://doi.org/10.2174/1874467214666210906125959
Permanent Link: http://hdl.handle.net/11104/0331831 - 2.0545100 - ÚMCH 2022 RIV CH eng J - Journal Article
Studenovský, Martin - Rumlerová, Anna - Kostka, Libor - Etrych, Tomáš
HPMA-based polymer conjugates for repurposed drug mebendazole and other imidazole-based therapeutics.
Polymers. Roč. 13, č. 15 (2021), č. článku 2530. E-ISSN 2073-4360
R&D Projects: GA ČR(CZ) GA19-01417S; GA ČR(CZ) GA19-05649S; GA MŠMT(CZ) LTAUSA18083
Institutional support: RVO:61389013
Keywords : mebendazole * drug delivery * drug repurposing
OECD category: Polymer science
Impact factor: 4.967, year: 2021
Method of publishing: Open access
https://www.mdpi.com/2073-4360/13/15/2530
Permanent Link: http://hdl.handle.net/11104/0321902 - 3.0542558 - ÚOCHB 2022 RIV CH eng J - Journal Article
Terrier, O. - Dilly, S. - Pizzorno, A. - Chalupská, Dominika - Humpolíčková, Jana - Bouřa, Evžen - Berenbaum, F. - Quideau, S. - Lina, B. - Fève, B. - Adnet, F. - Sabbah, M. - Rosa-Calatrava, M. - Maréchal, V. - Henri, J. - Slama-Schwok, A.
Antiviral Properties of the NSAID Drug Naproxen Targeting the Nucleoprotein of SARS-CoV-2 Coronavirus.
Molecules. Roč. 26, č. 9 (2021), č. článku 2593. E-ISSN 1420-3049
Institutional support: RVO:61388963
Keywords : antiviral * drug repurposing * SARS-CoV-2 * influenza * structure-based drug design * inflammation * nucleoprotein * oligomerization
OECD category: Biochemistry and molecular biology
Impact factor: 4.927, year: 2021
Method of publishing: Open access
https://doi.org/10.3390/molecules26092593
Permanent Link: http://hdl.handle.net/11104/0319945 - 4.0522796 - ÚMG 2020 RIV CH eng J - Journal Article
Mrkvova, Z. - Uldrijan, S. - Pombinho, António R. - Bartůněk, Petr - Slaninová, I.
Benzimidazoles Downregulate Mdm2 and MdmX and Activate p53 in MdmX Overexpressing Tumor Cells.
Molecules. Roč. 24, č. 11 (2019), č. článku 2152. E-ISSN 1420-3049
Institutional support: RVO:68378050
Keywords : benzimidazoles * drug repurposing * Mdm2 * MdmX * melanoma * p53
OECD category: Biochemistry and molecular biology
Impact factor: 3.267, year: 2019
Method of publishing: Open access
https://www.mdpi.com/1420-3049/24/11/2152
Permanent Link: http://hdl.handle.net/11104/0307228