Search results
- 1.0583492 - BFÚ 2024 RIV NL eng J - Journal Article
Sladekova, L. - Zgarbova, E. - Vrzal, R. - Vanda, D. - Soural, M. - Jakubcová, Klára - Vazquez-Gomez, Gerardo - Vondráček, Jan - Dvořák, Z.
Switching on/off aryl hydrocarbon receptor and pregnane X receptor activities by chemically modified tryptamines.
Toxicology Letters. Roč. 387, SEP 15 2023 (2023), s. 63-75. ISSN 0378-4274. E-ISSN 1879-3169
R&D Projects: GA ČR(CZ) GA22-00355S
Institutional support: RVO:68081707
Keywords : nuclear receptors * pxr * ahr * activation * antagonists * metabolism * tryptophan * ligands * target
OECD category: Toxicology
Impact factor: 3.5, year: 2022
Method of publishing: Limited access
https://www.sciencedirect.com/science/article/pii/S037842742301055X?via%3Dihub
Permanent Link: https://hdl.handle.net/11104/0351455 - 2.0579804 - ÚMG 2024 RIV US eng J - Journal Article
Mejdrova, I. - Dušek, J. - Škach, K. - Štefela, A. - Škoda, J. - Chalupský, Karel - Dohnalová, Klára - Pávková, I. - Kronenberger, T. - Rashidian, A. - Smutná, L. - Duchoslav, V. - Smutný, T. - Pávek, P. - Nencka, R.
Discovery of Novel Human Constitutive Androstane Receptor Agonists with the Imidazo[1,2-a]pyridine Structure.
Journal of Medicinal Chemistry. Roč. 66, č. 4 (2023), s. 2422-2456. ISSN 0022-2623. E-ISSN 1520-4804
R&D Projects: GA MŠMT(CZ) LM2015040; GA ČR GA22-05167S; GA MŠMT ED2.1.00/19.0395
Institutional support: RVO:68378050
Keywords : pregnane-x-receptor * car * activation * pxr * ligand * derivatives * identification * artemisinin * metabolites * expression
OECD category: Cell biology
Impact factor: 7.3, year: 2022
Method of publishing: Open access
https://pubs.acs.org/doi/10.1021/acs.jmedchem.2c01140
Permanent Link: https://hdl.handle.net/11104/0348603 - 3.0531243 - MBÚ 2021 RIV GB eng J - Journal Article
Zemanová, N. - Anzenbacher, P. - Zapletalová, I. - Jourová, L. - Hermanová, Petra - Hudcovic, Tomáš - Kozáková, Hana - Vodička, Martin - Pácha, Jiří - Anzenbacherová, E.
The role of the microbiome and psychosocial stress in the expression and activity of drug metabolizing enzymes in mice.
Scientific Reports. Roč. 10, č. 1 (2020), č. článku 8529. ISSN 2045-2322. E-ISSN 2045-2322
R&D Projects: GA ČR(CZ) GA17-09869S; GA ČR(CZ) GA19-08294S; GA ČR(CZ) GA18-02993S
Institutional support: RVO:61388971 ; RVO:67985823
Keywords : inflammation * health * PXR
OECD category: Microbiology; Physiology (including cytology) (FGU-C)
Impact factor: 4.380, year: 2020
Method of publishing: Open access
https://www.nature.com/articles/s41598-020-65595-9
Permanent Link: http://hdl.handle.net/11104/0309942 - 4.0474191 - ÚOCHB 2018 RIV IE eng J - Journal Article
Carazo, A. - Hyršová, L. - Dušek, J. - Chodounská, Hana - Horvátová, A. - Berka, K. - Bazgier, V. - Gan-Schreier, H. - Chamulitrat, W. - Kudová, Eva - Pávek, P.
Acetylated deoxycholic (DCA) and cholic (CA) acids are potent ligands of pregnane X (PXR) receptor.
Toxicology Letters. Roč. 265, Jan 4 (2017), s. 86-96. ISSN 0378-4274. E-ISSN 1879-3169
R&D Projects: GA TA ČR(CZ) TE01020028
Institutional support: RVO:61388963
Keywords : PXR * metabolism * bile acids * nuclear receptors * FXR
OECD category: Organic chemistry
Impact factor: 3.166, year: 2017
Permanent Link: http://hdl.handle.net/11104/0271341