Search results
- 1.0585153 - ÚOCHB 2025 RIV NL eng J - Journal Article
Feidakis, C. P. - Křivák, Radoslav - Hoksza, D. - Novotný, M.
AHoJ-DB: A PDB-wide Assignment of apo & holo Relationships Based on Individual Protein-Ligand Interactions.
Journal of Molecular Biology. (2024), č. článku 168545. ISSN 0022-2836. E-ISSN 1089-8638
R&D Projects: GA MŠMT(CZ) LM2018131
Research Infrastructure: e-INFRA CZ II - 90254
Institutional support: RVO:61388963
Keywords : apo-holo * protein structure * ligands * binding sites * drug design
Impact factor: 5.6, year: 2022
Method of publishing: Limited access
https://doi.org/10.1016/j.jmb.2024.168545
Permanent Link: https://hdl.handle.net/11104/0352895 - 2.0582851 - ÚOCHB 2025 RIV CH eng J - Journal Article
Matoušková, Zuzana - Orsághová, Katarína - Srb, Pavel - Pytelková, Jana - Kukačka, Zdeněk - Buša, Michal - Hajdušek, Ondřej - Šíma, Radek - Fábry, Milan - Novák, Petr - Horn, Martin - Kopáček, Petr - Mareš, Michael
An Unusual Two-Domain Thyropin from Tick Saliva: NMR Solution Structure and Highly Selective Inhibition of Cysteine Cathepsins Modulated by Glycosaminoglycans.
International Journal of Molecular Sciences. Roč. 25, č. 4 (2024), č. článku 2240. ISSN 1661-6596
R&D Projects: GA ČR(CZ) GA21-08826S; GA ČR(CZ) GA22-27695S; GA MŠMT(CZ) EF16_019/0000759; GA ČR(CZ) GA22-30920S; GA MŠMT(CZ) LUC23037
Institutional support: RVO:61388963 ; RVO:61388971 ; RVO:60077344
Keywords : cathepsin * cysteine protease * tick * parasite * saliva * thyropin * protease inhibitor * protein structure
Impact factor: 5.6, year: 2022
Method of publishing: Open access
https://doi.org/10.3390/ijms25042240
Permanent Link: https://hdl.handle.net/11104/0350903 - 3.0580493 - BC 2024 RIV CH eng J - Journal Article
Martins, Larissa Almeida - Buša, Michal - Chlastáková, A. - Kotál, Jan - Beránková, Z. - Stergiou, N. - Jmel, Mohamed Amine - Schmitt, E. - Chmelař, J. - Mareš, Michael - Kotsyfakis, Michalis
Protease-bound structure of Ricistatin provides insights into the mechanism of action of tick salivary cystatins in the vertebrate host.
Cellular and Molecular Life Sciences. Roč. 80, č. 11 (2023), č. článku 339. ISSN 1420-682X. E-ISSN 1420-9071
R&D Projects: GA ČR(CZ) GA19-07247S; GA MŠMT(CZ) EF16_019/0000759; GA MŠMT(CZ) EF16_019/0000729; GA MŠMT(CZ) LTAUSA19109
Institutional support: RVO:60077344 ; RVO:61388963
Keywords : ray crystal-structure * sialostatin-l * functional expression * cysteine cathepsins * mammalian legumain * ixodes-scapularis * inhibitors * stefin * generation * peptidase * Ixodes ricinus * Tick saliva * Cystatins * Protease inhibition * Protein structure * Host-parasite interactions
OECD category: Biochemistry and molecular biology; Biochemistry and molecular biology (UOCHB-X)
Impact factor: 8, year: 2022
Method of publishing: Limited access
https://link.springer.com/article/10.1007/s00018-023-04993-4
Permanent Link: https://hdl.handle.net/11104/0349268 - 4.0580418 - MBÚ 2024 RIV US eng M - Monography Chapter
Kalaninová, Zuzana - Fojtík, Lukáš - Chmelík, Josef - Novák, Petr - Volný, Michael - Man, Petr
Probing Antibody Structures by Hydrogen/Deuterium Exchange Mass Spectrometry.
Mass Spectrometry-Based Proteomics. New York: Humana, 2023 - (Gevaert, K.), s. 303-334. Methods in Molecular Biology. ISBN 978-1-0716-3456-1
R&D Projects: GA ČR(CZ) GA22-27695S; GA MŠMT(CZ) ED1.1.00/02.0109
EU Projects: European Commission(XE) 823839 - EPIC-XS
Institutional support: RVO:61388971
Keywords : Antibody * Hydrogen/deuterium exchange * Mass spectrometry * Proteolysis * Protein structure and dynamics * Biosimilars
OECD category: Biochemistry and molecular biology
https://link.springer.com/protocol/10.1007/978-1-0716-3457-8_17
Permanent Link: https://hdl.handle.net/11104/0349200 - 5.0574113 - ÚOCHB 2024 RIV GB eng J - Journal Article
Koudelková, Lenka - Pelantová, M. - Brůhová, Z. - Sztacho, M. - Pavlík, V. - Pánek, D. - Gemperle, J. - Talacko, P. - Brábek, J. - Rösel, D.
Phosphorylation of tyrosine 90 in SH3 domain is a new regulatory switch controlling Src kinase.
eLife. Roč. 12, July (2023), č. článku e82428. ISSN 2050-084X. E-ISSN 2050-084X
R&D Projects: GA MŠMT LX22NPO5102
Research Infrastructure: Czech-BioImaging II - 90129
Institutional support: RVO:61388963
Keywords : biochemistry * cell biology * cell transformation * chemical biology * invasiveness * mouse * phosphorylation * protein structure * SH3 domain * Src
OECD category: Biochemistry and molecular biology
Impact factor: 7.7, year: 2022
Method of publishing: Open access
https://doi.org/10.7554/eLife.82428
Permanent Link: https://hdl.handle.net/11104/0344468File Download Size Commentary Version Access 10.7554eLife.82428.pdf 0 3 MB Publisher’s postprint open-access - 6.0573702 - MBÚ 2024 RIV DE eng J - Journal Article
Mori, T. - Sun, X. - Kadlčík, Stanislav - Janata, Jiří - Abe, I.
Structure-Function Analysis of the S-Glycosylation Reaction in the Biosynthesis of Lincosamide Antibiotics.
Angewandte Chemie - International Edition. Roč. 62, č. 29 (2023), č. článku e2023049. ISSN 1433-7851. E-ISSN 1521-3773
R&D Projects: GA ČR(CZ) GJ20-09811Y; GA MŠMT(CZ) LX22NPO5103
Grant - others:AV ČR(CZ) LQ200202002
Program: Prémie Lumina quaeruntur
Institutional support: RVO:61388971
Keywords : LmbT * S-glycosyltransferase * lincomycin * ergothioneine * protein structure
OECD category: Microbiology
Impact factor: 16.6, year: 2022
Method of publishing: Open access
https://onlinelibrary.wiley.com/doi/10.1002/anie.202304989
Permanent Link: https://hdl.handle.net/11104/0344076File Download Size Commentary Version Access Mori - Structure‐Function Analysis of the S‐Glycosylation Reaction in the Biosynthesis of.pdf 1 3.9 MB Publisher’s postprint open-access - 7.0571673 - MBÚ 2024 RIV GB eng J - Journal Article
Pacheco-Garcia, J. L. - Anoz-Carbonell, E. - Loginov, Dmitry Sergej - Kavan, Daniel - Salido, E. - Man, Petr - Medina, M. - Pey, A. L.
Counterintuitive structural and functional effects due to naturally occurring mutations targeting the active site of the disease-associated NQO1 enzyme.
FEBS Journal. Roč. 290, č. 7 (2023), s. 1855-1873. ISSN 1742-464X. E-ISSN 1742-4658
R&D Projects: GA MŠMT(CZ) ED1.1.00/02.0109
EU Projects: European Commission(XE) 731077 - EU_FT-ICR_MS
Research Infrastructure: CIISB II - 90127
Institutional support: RVO:61388971
Keywords : catalytic mechanism * genotype-phenotype correlations * protein structure-function * structural stability
OECD category: Biochemistry and molecular biology
Impact factor: 5.4, year: 2022
Method of publishing: Open access
https://febs.onlinelibrary.wiley.com/doi/10.1111/febs.16677
Permanent Link: https://hdl.handle.net/11104/0343503 - 8.0571080 - ÚOCHB 2024 RIV GB eng J - Journal Article
Voitsitskyi, T. - Stratiichuk, R. - Koleiev, I. - Popryho, L. - Ostrovsky, Z. - Henitsoi, P. - Khropachov, I. - Vozniak, V. - Zhytar, R. - Nechepurenko, D. - Yesylevskyy, Semen - Nafiiev, A. - Starosyla, S.
3DProtDTA: a deep learning model for drug-target affinity prediction based on residue-level protein graphs.
RSC Advances. Roč. 13, č. 15 (2023), s. 10261-10272. E-ISSN 2046-2069
Institutional support: RVO:61388963
Keywords : drug-target affinity prediction * protein structure
OECD category: Physical chemistry
Impact factor: 3.9, year: 2022
Method of publishing: Open access
https://doi.org/10.1039/D3RA00281K
Permanent Link: https://hdl.handle.net/11104/0342384
Research data: GitHub - 9.0570585 - ÚOCHB 2024 RIV US eng J - Journal Article
Buša, Michal - Matoušková, Zuzana - Bartošová-Sojková, Pavla - Pachl, Petr - Řezáčová, Pavlína - Eichenberger, R. M. - Deplazes, P. - Horn, Martin - Štefanić, S. - Mareš, Michael
An evolutionary molecular adaptation of an unusual stefin from the liver fluke Fasciola hepatica redefines the cystatin superfamily.
Journal of Biological Chemistry. Roč. 299, č. 3 (2023), č. článku 102970. ISSN 0021-9258. E-ISSN 1083-351X
R&D Projects: GA MŠMT(CZ) EF16_019/0000729; GA ČR(CZ) GA19-17269S; GA ČR(CZ) GA21-16565S; GA MŠMT(CZ) LTAUSA19109
Institutional support: RVO:61388963 ; RVO:60077344
Keywords : cystatin * stefin * protease inhibitor * cysteine cathepsin * protein structure * protein evolution * helminth parasite
OECD category: Biochemistry and molecular biology
Impact factor: 4.8, year: 2022
Method of publishing: Open access
https://doi.org/10.1016/j.jbc.2023.102970
Permanent Link: https://hdl.handle.net/11104/0341888
Research data: RCSB PDB - 10.0562671 - BC 2023 RIV CH eng J - Journal Article
Alama-Bermejo, Gema - Bartošová-Sojková, Pavla - Atkinson, S.D. - Holzer, Astrid S. - Bartholomew, J.L.
Proteases as Therapeutic Targets Against the Parasitic Cnidarian Ceratonova shasta: Characterization of Molecules Key to Parasite Virulence In Salmonid Hosts.
Frontiers in Cellular and Infection Microbiology. Roč. 11, JAN 7 2022 (2022), č. článku 804864. ISSN 2235-2988. E-ISSN 2235-2988
R&D Projects: GA ČR(CZ) GX19-28399X; GA MŠMT(CZ) LTAUSA17201; GA ČR(CZ) GA21-16565S
Institutional support: RVO:60077344
Keywords : myxozoa * cysteine protease * aspartic protease * aminopeptidase * stefin * 3D protein structure * gene expression * homologous search
OECD category: Biochemistry and molecular biology
Impact factor: 5.7, year: 2022
Method of publishing: Open access
https://www.frontiersin.org/articles/10.3389/fcimb.2021.804864/full
Permanent Link: https://hdl.handle.net/11104/0335956