Search results
- 1.0536187 - ÚFCH JH 2021 RIV CH eng J - Journal Article
Scollo, Federica - La Rosa, C.
Amyloidogenic Intrinsically Disordered Proteins: New Insights into Their Self-Assembly and Their Interaction with Membranes.
Life. Roč. 10, č. 8 (2020), č. článku 144. E-ISSN 2075-1729
R&D Projects: GA ČR(CZ) GX19-26854X
Institutional support: RVO:61388955
Keywords : alpha-synuclein aggregation * mammalian prion protein * in-vitro conversion * a-beta * precursor protein * lipid-membranes * parkinsons-disease * molecular-dynamics * fibril formation * nmr structure * intrinsically disordered proteins * lipid * membrane * cmc * amyloids
OECD category: Physical chemistry
Impact factor: 3.817, year: 2020
Method of publishing: Open access
Permanent Link: http://hdl.handle.net/11104/0313998File Download Size Commentary Version Access 0536187.pdf 1 1.9 MB open access Publisher’s postprint open-access - 2.0494335 - ÚMG 2019 RIV CH eng J - Journal Article
Seipold, L. - Altmeppen, H. - Koudelka, T. - Tholey, A. - Kašpárek, Petr - Sedláček, Radislav - Schweizer, M. - Baer, J. - Mikhaylova, M. - Glatzel, M. - Saftig, P.
In vivo regulation of the A disintegrin and metalloproteinase 10 (ADAM10) by the tetraspanin 15.
Cellular and Molecular Life Sciences. Roč. 75, č. 17 (2018), s. 3251-3267. ISSN 1420-682X. E-ISSN 1420-9071
R&D Projects: GA MŠMT ED2.1.00/19.0395
Institutional support: RVO:68378050
Keywords : adam10 * N-cadherin * Prion protein * Tetraspanin
OECD category: Biochemistry and molecular biology
Impact factor: 7.014, year: 2018
Permanent Link: http://hdl.handle.net/11104/0287562 - 3.0477495 - ÚOCHB 2018 RIV GB eng J - Journal Article
Šafařík, Martin - Moško, T. - Zawada, Zbigniew - Šafaříková, E. - Dračínský, Martin - Holada, K. - Šebestík, Jaroslav
Reactivity of 9-aminoacridine drug quinacrine with glutathione limits its antiprion activity.
Chemical Biology & Drug Design. Roč. 89, č. 6 (2017), s. 932-942. ISSN 1747-0277. E-ISSN 1747-0285
R&D Projects: GA ČR(CZ) GA14-00431S; GA ČR GA15-09072S; GA ČR(CZ) GA16-00270S
Institutional support: RVO:61388963
Keywords : antiprion activity * failure in clinical trials * nucleophilic displacement * prion protein binding * quinacrine
OECD category: Physical chemistry
Impact factor: 2.328, year: 2017
Permanent Link: http://hdl.handle.net/11104/0273837 - 4.0392499 - ÚOCHB 2014 RIV AT eng J - Journal Article
Zawada, Zbigniew - Šafařík, Martin - Dvořáková, E. - Janoušková, O. - Březinová, Anna - Stibor, Ivan - Holada, K. - Bouř, Petr - Hlaváček, Jan - Šebestík, Jaroslav
Quinacrine reactivity with prion proteins and prion-derived peptides.
Amino Acids. Roč. 44, č. 5 (2013), s. 1279-1292. ISSN 0939-4451. E-ISSN 1438-2199
R&D Projects: GA ČR GA203/07/1517
Institutional support: RVO:61388963
Keywords : quinacrine * prion protein and peptide model reactions * solid phase and recombinant synthesis
Subject RIV: CE - Biochemistry
Impact factor: 3.653, year: 2013
Permanent Link: http://hdl.handle.net/11104/0221352 - 5.0379984 - ÚOCHB 2013 RIV AT eng J - Journal Article
Šebestík, Jaroslav - Zawada, Zbigniew - Šafařík, Martin - Hlaváček, Jan
Comparative syntheses of peptides and peptide thioesters derived from mouse and human prion proteins.
Amino Acids. Roč. 43, č. 3 (2012), s. 1297-1309. ISSN 0939-4451. E-ISSN 1438-2199
R&D Projects: GA ČR GA203/07/1517
Institutional research plan: CEZ:AV0Z40550506
Keywords : prion protein segments * classical synthesis * chemical ligation synthesis * peptide thioesters
Subject RIV: CC - Organic Chemistry
Impact factor: 3.914, year: 2012
Permanent Link: http://hdl.handle.net/11104/0210822 - 6.0370683 - ÚOCHB 2012 CZ eng C - Conference Paper (international conference)
Zawada, Zbigniew - Šafařík, Martin - Šebestík, Jaroslav - Stibor, Ivan - Bouř, Petr
Reaction of prion protein with quinacrine.
Biologically Active Peptides. 12th Conference. Praha: Institute of Organic Chemistry and Biochemistry AS CR, v. v. i, 2011 - (Slaninová, J.), s. 163-165. Collection Symposium Series, 13. ISBN 978-80-86241-44-9.
[Biologically Active Peptides /12./. Praha (CZ), 27.04.2011-29.04.2011]
R&D Projects: GA ČR GA203/07/1517
Institutional research plan: CEZ:AV0Z40550506
Keywords : prion protein * quinacrine * transition state calculation * activation energy prediction
Subject RIV: CC - Organic Chemistry
Permanent Link: http://hdl.handle.net/11104/0204408 - 7.0359701 - ÚOCHB 2012 CZ eng A - Abstract
Zawada, Zbigniew - Šafařík, Martin - Březinová, Anna - Dvořáková, E. - Šebestík, Jaroslav - Hlaváček, Jan - Holada, K. - Stibor, Ivan - Bouř, Petr
Reaction of prion protein with quinacrine.
Biologically Active Peptides /12./. Praha: Ústav organické chemie a biochemie AV ČR, v.v.i, 2011 - (Slaninová, J.; Borovičková, L.). s. 73-73. ISBN 978-80-86241-36-4.
[Biologically Active Peptides /12./. 27.04.2011-29.04.2011, Praha]
R&D Projects: GA ČR GA203/07/1517
Institutional research plan: CEZ:AV0Z40550506
Keywords : prion protein * quinacrine
Subject RIV: CC - Organic Chemistry
Permanent Link: http://hdl.handle.net/11104/0197438 - 8.0346330 - ÚOCHB 2011 RIV AT eng J - Journal Article
Niederhafner, Petr - Gut, Vladimír - Ježek, Jan - Buděšínský, Miloš - Kašička, Václav - Wünsch, Erich - Hlaváček, Jan
Synthetic study on cystinyl peptides using solution and solid phase metodology: human IgG1 hinge region.
Amino Acids. Roč. 39, č. 3 (2010), s. 641-650. ISSN 0939-4451. E-ISSN 1438-2199
R&D Projects: GA ČR GA203/03/1362; GA ČR GA203/07/1517
Institutional research plan: CEZ:AV0Z40550506
Keywords : hinge region * immunoglobulin * prion protein * solution synthesis * solid phase synthesis
Subject RIV: CC - Organic Chemistry
Impact factor: 4.106, year: 2010
Permanent Link: http://hdl.handle.net/11104/0187389 - 9.0328840 - ÚOCHB 2010 AT eng A - Abstract
Zawada, Z. - Šebestík, Jaroslav - Bednárová, Lucie - Bouř, Petr - Hlaváček, Jan - Stibor, Ivan
Synthetic study on prion protein fragments using a SPPS and native chemical ligation.
[Syntetická studie o fragmentech prionové bílkoviny využívající SPPS a nativní.]
Amino Acids. Springer. Roč. 37, Suppl. 1 (2009), s. 44-44. ISSN 0939-4451. E-ISSN 1438-2199.
[International Congress on Amino Acids, Peptides and Proteins /11./. 03.08.2009-07.08.2009, Vienna]
Institutional research plan: CEZ:AV0Z40550506
Keywords : prion protein * SPPS * native chemical ligation * fragments
Subject RIV: CC - Organic Chemistry
Permanent Link: http://hdl.handle.net/11104/0175045 - 10.0314157 - ÚOCHB 2009 GB eng A - Abstract
Zawada, Zbigniew - Šebestík, Jaroslav - Bouř, Petr - Hlaváček, Jan - Stibor, Ivan
Novel synthetic approach to the prion protein: Kinetic study optimization of a native chemical ligation.
[Nový syntetický přístup k prionové bílkovině: Kinetická studie optimalizace přirozené chemické ligace.]
Journal of Peptide Science. Roč. 14, č. 8 (2008), s. 76-77. ISSN 1075-2617. E-ISSN 1099-1387.
[European Peptide Symposium /30./. 31.08.2008-05.09.2008, Helsinki]
R&D Projects: GA ČR GA203/07/1517
Institutional research plan: CEZ:AV0Z40550506
Keywords : prion protein * neurodegenerative diseases * chemical synthesis * ligation conditions
Subject RIV: CC - Organic Chemistry
Permanent Link: http://hdl.handle.net/11104/0164754