Search results
- 1.0562658 - ÚOCHB 2023 RIV GB eng J - Journal Article
Misehe, Mbilo - Klíma, Martin - Matoušová, Marika - Chalupská, Dominika - Dejmek, Milan - Šála, Michal - Mertlíková-Kaiserová, Helena - Bouřa, Evžen - Nencka, Radim
Structure-based design and modular synthesis of novel PI4K class II inhibitors bearing a 4-aminoquinazoline scaffold.
Bioorganic and Medicinal Chemistry Letters. Roč. 76, November (2022), č. článku 129010. ISSN 0960-894X. E-ISSN 1464-3405
R&D Projects: GA MŠMT(CZ) EF16_019/0000729; GA MZd(CZ) NU20-05-00472
Institutional support: RVO:61388963
Keywords : phosphatidylinositol 4-kinase class II * PI4K2A inhibitor * quinazoline derivative * SAR investigation * ATP-binding site
OECD category: Biochemistry and molecular biology
Impact factor: 2.7, year: 2022
Method of publishing: Limited access
https://doi.org/10.1016/j.bmcl.2022.129010
Permanent Link: https://hdl.handle.net/11104/0334914
Research data: PDB - 2.0540793 - ÚOCHB 2022 RIV DE eng J - Journal Article
Junková, Petra - Neubergerová, M. - Kalachova, Tetiana - Valentová, O. - Janda, M.
Regulation of the microsomal proteome by salicylic acid and deficiency of phosphatidylinositol-4-kinases β1 and β2 in Arabidopsis thaliana.
Proteomics. Roč. 21, č. 5 (2021), č. článku 2000223. ISSN 1615-9853. E-ISSN 1615-9861
R&D Projects: GA ČR GA17-05151S; GA MŠMT(CZ) EF16_019/0000729; GA MŠMT(CZ) EF16_019/0000738
Institutional support: RVO:61388963 ; RVO:61389030
Keywords : Arabidopsis thaliana * label-free proteomics * microsomes * phosphatidylinositol-4-kinase * salicylic acid
OECD category: Biochemical research methods
Impact factor: 5.393, year: 2021
Method of publishing: Limited access
https://doi.org/10.1002/pmic.202000223
Permanent Link: http://hdl.handle.net/11104/0318393 - 3.0509290 - ÚEB 2020 RIV NL eng J - Journal Article
Kalachova, Tetiana - Leontovyčová, Hana - Iakovenko, Oksana - Pospíchalová, Romana - Maršík, P. - Klouček, P. - Janda, Martin - Valentová, O. - Kocourková, Daniela - Martinec, Jan - Burketová, Lenka - Ruelland, E.
Interplay between phosphoinositides and actin cytoskeleton in the regulation of immunity related responses in Arabidopsis thaliana seedlings.
Environmental and Experimental Botany. Roč. 167, NOV (2019), č. článku 103867. ISSN 0098-8472. E-ISSN 1873-7307
R&D Projects: GA ČR GA17-05151S; GA MŠMT(CZ) EF16_019/0000738
Grant - others:OPPK(XE) CZ.2.16/3.1.00/21519
Institutional support: RVO:61389030
Keywords : Actin * Callose * Latrunculin B * phosphatidylinositol-4-kinase * Salicylic acid
OECD category: Cell biology
Impact factor: 4.027, year: 2019
Method of publishing: Open access
http://dx.doi.org/10.1016/j.envexpbot.2019.103867
Permanent Link: http://hdl.handle.net/11104/0300111File Download Size Commentary Version Access 2019_Kalachova_ENVIRONMENTAL AND EXPERIMENTAL BOTANY_103867.pdf 5 1.8 MB Other open-access - 4.0470966 - ÚOCHB 2017 US eng A - Abstract
Nencka, Radim - Mejdrová, Ivana - Plačková, Pavla - Šála, Michal - Chalupská, Dominika - Strunin, Dmytro - Procházková, Eliška - Weber, Jan - Bouřa, Evžen - Müller, Ch. - Ziebuhr, J. - Birkuš, G.
Rational Design of Selective Phosphatidylinositol 4-Kinase IIIbeta Inhibitors as Highly Potent, Broad-Spectrum Antiviral Agents.
29th International Conference on Antiviral Research (ICAR). La Jolla: International Society for Antiviral Research, 2016. s. 81.
[International Conference on Antiviral Research (ICAR) /29./. 17.04.2016-21.04.2016, La Jolla]
Institutional support: RVO:61388963
Keywords : phosphatidylinositol 4-kinase * antivirals
Subject RIV: CC - Organic Chemistry
Permanent Link: http://hdl.handle.net/11104/0268478 - 5.0460249 - ÚOCHB 2017 RIV GB eng J - Journal Article
Šála, Michal - Kögler, Martin - Plačková, Pavla - Mejdrová, Ivana - Hřebabecký, Hubert - Procházková, Eliška - Strunin, Dmytro - Lee, G. - Birkuš, G. - Weber, Jan - Mertlíková-Kaiserová, Helena - Nencka, Radim
Purine analogs as phosphatidylinositol 4-kinase III beta inhibitors.
Bioorganic and Medicinal Chemistry Letters. Roč. 26, č. 11 (2016), s. 2706-2712. ISSN 0960-894X. E-ISSN 1464-3405
R&D Projects: GA ČR GA15-09310S; GA MŠMT LO1302
Institutional support: RVO:61388963
Keywords : phosphatidylinositol 4-kinase * purine * PI4K III beta * antiviral agent * hepatitis C virus
Subject RIV: CC - Organic Chemistry
Impact factor: 2.454, year: 2016
Permanent Link: http://hdl.handle.net/11104/0260372 - 6.0450522 - ÚOCHB 2016 DE eng A - Abstract
Bäumlová, Adriana - Bouřa, Evžen
Structural and functional analysis of the phosphatidylinositol 4-kinase IIalpha.
European Biophysics Journal With Biophysics Letters. Roč. 44, Suppl 1 (2015), S50. ISSN 0175-7571. E-ISSN 1432-1017.
[EBSA European Biophysics Congress /10./. 18.07.2015-22.07.2015, Dresden]
Institutional support: RVO:61388963
Keywords : phosphatidylinositol 4-kinase IIalpha * crystal structure
Subject RIV: CE - Biochemistry
Permanent Link: http://hdl.handle.net/11104/0251788 - 7.0449209 - ÚOCHB 2016 RIV US eng J - Journal Article
Bouřa, Evžen - Nencka, Radim
Phosphatidylinositol 4-kinases: Function, structure, and inhibition.
Experimental Cell Research. Roč. 337, č. 2 (2015), s. 136-145. ISSN 0014-4827. E-ISSN 1090-2422
R&D Projects: GA ČR GJ15-21030Y; GA MŠMT LO1302; GA ČR GA15-09310S
EU Projects: European Commission(XE) 333916 - STARPI4K
Institutional support: RVO:61388963
Keywords : phosphatidylinositol 4-kinase * inhibitor * crystal structure * virus
Subject RIV: CC - Organic Chemistry
Impact factor: 3.378, year: 2015
Permanent Link: http://hdl.handle.net/11104/0250870 - 8.0444785 - ÚOCHB 2016 RIV US eng J - Journal Article
Mejdrová, Ivana - Chalupská, Dominika - Kögler, Martin - Šála, Michal - Plačková, Pavla - Bäumlová, Adriana - Hřebabecký, Hubert - Procházková, Eliška - Dejmek, Milan - Guillon, Rémi - Strunin, Dmytro - Weber, Jan - Lee, G. - Birkuš, G. - Mertlíková-Kaiserová, Helena - Bouřa, Evžen - Nencka, Radim
Highly Selective Phosphatidylinositol 4-Kinase III beta Inhibitors and Structural Insight into Their Mode of Action.
Journal of Medicinal Chemistry. Roč. 58, č. 9 (2015), s. 3767-3793. ISSN 0022-2623. E-ISSN 1520-4804
R&D Projects: GA MŠMT LO1302; GA ČR GA15-09310S; GA ČR GJ15-21030Y
EU Projects: European Commission(XE) 333916 - STARPI4K
Institutional support: RVO:61388963
Keywords : phosphatidylinositol 4-kinase III beta * broad-spectrum antiviral agents * positive-sense RNA viruses
Subject RIV: CC - Organic Chemistry
Impact factor: 5.589, year: 2015
Permanent Link: http://hdl.handle.net/11104/0247293 - 9.0441351 - ÚEB 2015 RIV US eng J - Journal Article
Janda, Martin - Šašek, Vladimír - Ruelland, E.
The Arabidopsis pi4kIIIβ1β2 double mutant is salicylic acid-overaccumulating: A new example of salicylic acid influence on plant stature.
Plant Signaling & Behavior. Roč. 9, č. 12 (2014). ISSN 1559-2316. E-ISSN 1559-2324
R&D Projects: GA ČR(CZ) GAP501/11/1654
Institutional support: RVO:61389030
Keywords : phosphatidylinositol-4-kinase * plant growth * salicylic acid
Subject RIV: ED - Physiology
http://gateway.isiknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=Alerting&SrcApp=Alerting&DestApp=MEDLINE&DestLinkType=FullRecord&UT=25482755
Permanent Link: http://hdl.handle.net/11104/0244378File Download Size Commentary Version Access 2014_Janda_Plant Signaling & Behavior_e977210.pdf 1 71 KB Other open-access - 10.0430390 - ÚOCHB 2015 RIV DE eng J - Journal Article
Dejmek, Milan - Šála, Michal - Plačková, Pavla - Hřebabecký, Hubert - Borreda, L. M. - Neyts, J. - Dračínský, Martin - Procházková, Eliška - Jansa, Petr - Leyssen, P. - Mertlíková-Kaiserová, Helena - Nencka, Radim
Synthesis of Novel Purine-Based Coxsackievirus Inhibitors Bearing Polycylic Substituents at the N-9 Position.
Archiv der Pharmazie. Roč. 347, č. 7 (2014), s. 478-485. ISSN 0365-6233. E-ISSN 1521-4184
R&D Projects: GA ČR GAP303/11/1297
Institutional support: RVO:61388963
Keywords : antiviral * coxsackievirus B3 * enteroviruses * phosphatidylinositol 4-kinase (PI4K) * purines
Subject RIV: CC - Organic Chemistry
Impact factor: 1.531, year: 2014
Permanent Link: http://hdl.handle.net/11104/0235359