Search results
- 1.0574027 - FGÚ 2024 RIV CH eng J - Journal Article
Holendová, Blanka - Plecitá-Hlavatá, Lydie
Cysteine residues in signal transduction and its relevance in pancreatic beta cells.
Frontiers in Endocrinology. Roč. 14, Jun 29 (2023), č. článku 1221520. ISSN 1664-2392. E-ISSN 1664-2392
R&D Projects: GA MŠMT(CZ) LX22NPO5104; GA ČR(CZ) GA22-11439S
Institutional support: RVO:67985823
Keywords : cysteine * thiol * pancreatic beta cells * posttranslational modifications * redox signaling
OECD category: Endocrinology and metabolism (including diabetes, hormones)
Impact factor: 5.2, year: 2022
Method of publishing: Open access
https://doi.org/10.3389/fendo.2023.1221520
Permanent Link: https://hdl.handle.net/11104/0344388File Download Size Commentary Version Access 23_0071_0574027.pdf 0 2.3 MB Publisher’s postprint open-access 23_0071_correction_2024.pdf 1 221.2 KB Publisher’s postprint open-access - 2.0570547 - FGÚ 2024 RIV DE eng J - Journal Article
Pavluch, Vojtěch - Engstová, Hana - Špačková, Jitka - Ježek, Petr
Deficiency of transcription factor Nkx6.1 does not prevent insulin secretion in INS-1E cells.
Scientific Reports. Roč. 13, č. 1 (2023), č. článku 683. ISSN 2045-2322. E-ISSN 2045-2322
R&D Projects: GA MŠMT(CZ) LX22NPO5104; GA ČR(CZ) GA20-00408S
Institutional support: RVO:67985823
Keywords : Nkx6.1 * pancreatic-beta-cells * GLUT2 * pyruvate carboxylase * glucose-stimulated insulin secretion
OECD category: Endocrinology and metabolism (including diabetes, hormones)
Impact factor: 4.6, year: 2022
Method of publishing: Open access
https://doi.org/10.1038/s41598-023-27985-7
Permanent Link: https://hdl.handle.net/11104/0341847File Download Size Commentary Version Access 23_0021_0570547.pdf 0 4.4 MB Publisher’s postprint open-access - 3.0551050 - FGÚ 2022 RIV GB eng M - Monography Chapter
Ježek, Petr - Holendová, Blanka - Jabůrek, Martin - Tauber, Jan - Dlasková, Andrea - Plecitá-Hlavatá, Lydie
Redox Signaling is Essential for Insulin Secretion.
Type 2 Diabetes - From Pathophysiology to Cyber Systems. London: IntechOpen, 2021 - (Stoian Pantea, A.), s. 33-63. ISBN 978-1-83881-905-7
R&D Projects: GA ČR(CZ) GA20-00408S
Institutional support: RVO:67985823
Keywords : pancreatic beta-cells * insulin secretion * redox signaling * NADPH oxidase 4 * branched chain ketoacid oxidation * fatty acid beta-oxidation * ATP-sensitive K+ channel * GLP1 * GPR40
OECD category: Endocrinology and metabolism (including diabetes, hormones)
https://www.intechopen.com/chapters/73867
Permanent Link: http://hdl.handle.net/11104/0326368 - 4.0542431 - FGÚ 2022 RIV CH eng J - Journal Article
Benáková, Štěpánka - Holendová, Blanka - Plecitá-Hlavatá, Lydie
Redox Homeostasis in Pancreatic beta-Cells: From Development to Failure.
Antioxidants. Roč. 10, č. 4 (2021), č. článku 526. E-ISSN 2076-3921
R&D Projects: GA ČR(CZ) GA20-00408S
Institutional support: RVO:67985823
Keywords : redox signaling * oxidative stress * redox homeostasis * pancreatic beta-cells * de/differentiation * inflammation
OECD category: Endocrinology and metabolism (including diabetes, hormones)
Impact factor: 7.675, year: 2021
Method of publishing: Open access
https://www.mdpi.com/2076-3921/10/4/526
Permanent Link: http://hdl.handle.net/11104/0319840 - 5.0541624 - FGÚ 2022 RIV CH eng J - Journal Article
Ježek, Petr - Holendová, Blanka - Jabůrek, Martin - Tauber, Jan - Dlasková, Andrea - Plecitá-Hlavatá, Lydie
The Pancreatic beta-Cell: The Perfect Redox System.
Antioxidants. Roč. 10, č. 2 (2021), č. článku 197. E-ISSN 2076-3921
R&D Projects: GA ČR(CZ) GA20-00408S
Institutional support: RVO:67985823
Keywords : pancreatic beta-cells * insulin secretion * redox signaling * NADPH oxidase 4 * branched-chain ketoacid oxidation * fatty-acid-stimulated insulin secretion * TRPM channels * ATP-sensitive K+ channel * GLP-1 * GPR40
OECD category: Endocrinology and metabolism (including diabetes, hormones)
Impact factor: 7.675, year: 2021
Method of publishing: Open access
https://www.mdpi.com/2076-3921/10/2/197
Permanent Link: http://hdl.handle.net/11104/0319157 - 6.0532352 - FGÚ 2021 RIV US eng J - Journal Article
Plecitá-Hlavatá, Lydie - Engstová, Hana - Holendová, Blanka - Tauber, Jan - Špaček, Tomáš - Petrásková, Lucie - Křen, Vladimír - Špačková, Jitka - Gotvaldová, Klára - Ježek, Jan - Dlasková, Andrea - Smolková, Katarína - Ježek, Petr
Mitochondrial Superoxide Production Decreases on Glucose-Stimulated Insulin Secretion in Pancreatic beta Cells Due to Decreasing Mitochondrial Matrix NADH/NAD(+) Ratio.
Antioxidants & Redox Signaling. Roč. 33, č. 12 (2020), s. 789-815. ISSN 1523-0864. E-ISSN 1557-7716
R&D Projects: GA ČR(CZ) GA16-06700S; GA ČR(CZ) GA17-01813S; GA ČR(CZ) GA20-00408S
Institutional support: RVO:67985823 ; RVO:61388971
Keywords : mitochondrial superoxide generation * pancreatic beta cells * glucose-stimulated insulin secretion * Complex I * NADH/NAD(+) ratio * fluorescence lifetime imaging
OECD category: Endocrinology and metabolism (including diabetes, hormones); Analytical chemistry (MBU-M)
Impact factor: 8.401, year: 2020
Method of publishing: Open access
https://www.liebertpub.com/doi/10.1089/ars.2019.7800
Permanent Link: http://hdl.handle.net/11104/0310854 - 7.0510404 - FGÚ 2020 RIV US eng J - Journal Article
Ježek, Petr - Jabůrek, Martin - Plecitá-Hlavatá, Lydie
Contribution of Oxidative Stress and Impaired Biogenesis of Pancreatic beta-Cells to Type 2 Diabetes.
Antioxidants & Redox Signaling. Roč. 31, č. 10 (2019), s. 722-751. ISSN 1523-0864. E-ISSN 1557-7716
R&D Projects: GA ČR(CZ) GA16-06700S; GA ČR(CZ) GA17-01813S
Institutional support: RVO:67985823
Keywords : pancreatic beta-cells * type 2 diabetes * oxidative stress * impaired redox signaling * beta-cell identity self-checking * dedifferentiation
OECD category: Endocrinology and metabolism (including diabetes, hormones)
Impact factor: 7.040, year: 2019
Method of publishing: Open access
https://doi.org/10.1089/ars.2018.7656
Permanent Link: http://hdl.handle.net/11104/0300914 - 8.0506716 - FGÚ 2020 RIV US eng J - Journal Article
Plecitá-Hlavatá, Lydie - Engstová, Hana - Ježek, Jan - Holendová, Blanka - Tauber, Jan - Petrásková, Lucie - Křen, Vladimír - Ježek, Petr
Potential of Mitochondria-Targeted Antioxidants to Prevent Oxidative Stress in Pancreatic beta-cells.
Oxidative Medicine and Cellular Longevity. Roč. 2019, č. 2019 (2019), č. článku 1826303. ISSN 1942-0900. E-ISSN 1942-0994
R&D Projects: GA ČR(CZ) GA16-06700S; GA ČR(CZ) GA17-01813S; GA ČR(CZ) GA18-00121S
Institutional support: RVO:67985823 ; RVO:61388971
Keywords : pancreatic beta cells * pancreatic islets * mitochondria- targeted antioxidants * oxidative stress * SkQ * S3QEL * S1QEL
OECD category: Cell biology; Physiology (including cytology) (MBU-M)
Impact factor: 5.076, year: 2019
Method of publishing: Open access
https://doi.org/10.1155/2019/1826303
Permanent Link: http://hdl.handle.net/11104/0297909 - 9.0493406 - FGÚ 2019 RIV CH eng J - Journal Article
Ježek, Petr - Jabůrek, Martin - Holendová, Blanka - Plecitá-Hlavatá, Lydie
Fatty Acid-Stimulated Insulin Secretion vs. Lipotoxicity.
Molecules. Roč. 23, č. 6 (2018), č. článku 1483. E-ISSN 1420-3049
R&D Projects: GA ČR(CZ) GA16-06700S
Institutional support: RVO:67985823
Keywords : fatty acids * fatty acid-stimulated insulin secretion * GPR40 * pancreatic beta-cells * oxidative stress * lipotoxicity * type 2 diabetes * low-grade inflammation
OECD category: Endocrinology and metabolism (including diabetes, hormones)
Impact factor: 3.060, year: 2018
Permanent Link: http://hdl.handle.net/11104/0286770 - 10.0463585 - ÚOCHB 2017 RIV US eng J - Journal Article
Frank, J. A. - Yushchenko, Dmytro A. - Hodson, D. J. - Lipstein, N. - Nagpal, J. - Rutter, G. A. - Rhee, J. S. - Gottschalk, A. - Brose, N. - Schultz, C. - Trauner, D.
Photoswitchable diacylglycerols enable optical control of protein kinase C.
Nature Chemical Biology. Roč. 12, č. 9 (2016), s. 755-762. ISSN 1552-4450. E-ISSN 1552-4469
Institutional support: RVO:61388963
Keywords : pancreatic beta cells * Caenorhabditis elegans * insulin secretion
Subject RIV: CE - Biochemistry
Impact factor: 15.066, year: 2016
Permanent Link: http://hdl.handle.net/11104/0262736