Search results
- 1.0583206 - BFÚ 2024 RIV GB eng J - Journal Article
Kratochvilová, Libuše - Vojsovič, Matůš - Valková, Natalia - Šislerová, Lucie - El Rashed, Z. - Inga, A. - Monti, P. - Brázda, Václav
The presence of a G-quadruplex prone sequence upstream of a minimal promoter increases transcriptional activity in the yeasti Saccharomyces/i cerevisiae.
Bioscience Reports. Roč. 43, č. 12 (2023), č. článku BSR20231348. ISSN 0144-8463. E-ISSN 1573-4935
R&D Projects: GA ČR(CZ) GA22-21903S
Institutional support: RVO:68081707
Keywords : small-molecule * thioflavin t * dna * p53 * transactivation * visualization * specificities * evolution * region
OECD category: Biochemistry and molecular biology
Impact factor: 4, year: 2022
Method of publishing: Limited access
https://portlandpress.com/bioscirep/article/43/12/BSR20231348/233764/The-presence-of-a-G-quadruplex-prone-sequence
Permanent Link: https://hdl.handle.net/11104/0351205 - 2.0579255 - FZÚ 2024 RIV NL eng J - Journal Article
Vávra, J. - Sergunin, A. - Pompach, P. - Savchenko, Dariia - Hraníček, J. - Šloufová, I. - Shimizu, T. - Martinková, M.
Characterization of the interaction between the tumour suppressor p53 and heme and its role in the protein conformational dynamics studied by various spectroscopic techniques and hydrogen/deuterium exchange coupled with mass spectrometry.
Journal of Inorganic Biochemistry. Roč. 243, June (2023), č. článku 112180. ISSN 0162-0134. E-ISSN 1873-3344
R&D Projects: GA MŠMT(CZ) EF16_019/0000760
Grant - others:OP VVV - SOLID21(XE) CZ.02.1.01/0.0/0.0/16_019/0000760
Institutional support: RVO:68378271
Keywords : conformational dynamics * intrinsically disordered regions * Heme interaction * Heme-responsive sensor * p53 transcription factor * signal transduction
OECD category: Inorganic and nuclear chemistry
Impact factor: 3.9, year: 2022
Method of publishing: Limited access
https://doi.org/10.1016/j.jinorgbio.2023.112180
Permanent Link: https://hdl.handle.net/11104/0348102 - 3.0578776 - ÚMG 2024 RIV DE eng J - Journal Article
Burocziová, Monika - Daněk, Petr - Oravetzová, Anna - Chalupová, Zuzana - Alberich-Jorda, Meritxell - Macůrek, Libor
Ppm1d truncating mutations promote the development of genotoxic stress-induced AML.
Leukemia. Roč. 37, Sep (2023), s. 2209-2220. ISSN 0887-6924. E-ISSN 1476-5551
R&D Projects: GA ČR GA20-11931S; GA MŠMT LX22NPO5102; GA MŠMT(CZ) LM2018129; GA MŠMT(CZ) EF18_046/0016045
Institutional support: RVO:68378050
Keywords : cell self-renewal * stem-cell * phosphatase wip1 * p53 * cycle * hematopoiesis * tumorigenesis * quiescence * maturation * proteins
OECD category: Biochemistry and molecular biology
Impact factor: 11.4, year: 2022
Method of publishing: Open access
https://www.nature.com/articles/s41375-023-02030-8
Permanent Link: https://hdl.handle.net/11104/0347691File Download Size Commentary Version Access Buroziova_2023.pdf 1 2.4 MB Publisher’s postprint open-access - 4.0578357 - ÚMG 2025 RIV US eng J - Journal Article
Martiníková, Andra Stefania - Stoyanov, Miroslav - Oravetzová, Anna - Kok, Y. P. - Yu, S. - Dobrovolná, Jana - Janščák, Pavel - van Vugt, M. - Macůrek, Libor
PPM1D activity promotes the replication stress caused by cyclin E1 overexpression.
Molecular Oncology. Roč. 18, č. 1 (2024), s. 6-20. ISSN 1574-7891. E-ISSN 1878-0261
R&D Projects: GA MŠMT LX22NPO5102; GA MŠMT(CZ) LM2018129; GA ČR GX21-22593X; GA MŠMT(CZ) EF18_046/0016045
Institutional support: RVO:68378050
Keywords : dna-damage response * wip1 phosphatase * p53 * cancer * mutations * barrier * tumorigenesis * instability * inhibition * chromatin * cancer * cell cycle * cyclin E1 * PPM1D phosphatase * replication stress
OECD category: Biochemistry and molecular biology
Impact factor: 6.6, year: 2022
Method of publishing: Open access
https://febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13433
Permanent Link: https://hdl.handle.net/11104/0349661File Download Size Commentary Version Access Molecular Oncology - 2023 - Martinikova - PPM1D activity promotes the replication stress caused by cyclin E1 overexpression.pdf 2 1.9 MB Publisher’s postprint open-access - 5.0574514 - BFÚ 2024 RIV NL eng J - Journal Article
Goswami, Pratik - Šislerová, Lucie - Dobrovolná, Michaela - Havlík, J. - Šťastný, J. - Brázda, Václav
Interaction of C-terminal p53 isoforms depends strongly upon DNA sequence and topology.
Biochimie. Roč. 208, MAY 2023 (2023), s. 93-99. ISSN 0300-9084. E-ISSN 1638-6183
R&D Projects: GA ČR(CZ) GA22-21903S
Institutional support: RVO:68081707
Keywords : p53 isoforms * G-quadruplex * Atomic force microscopy * p53-DNA binding * Supercoiled DNA
OECD category: Biochemistry and molecular biology
Impact factor: 3.9, year: 2022
Method of publishing: Limited access
https://www.sciencedirect.com/science/article/pii/S0300908422003352?via%3Dihub
Permanent Link: https://hdl.handle.net/11104/0350064 - 6.0572133 - BFÚ 2024 RIV NL eng J - Journal Article
Ostatná, Veronika - Černocká, Hana - Galicová, Tatiana - Hasoň, Stanislav
Electrochemical analysis of proteins important in cancer: Behavior of anterior gradient receptors, p53 protein and their complexes at charged surfaces.
Current Opinion in Electrochemistry. Roč. 39, JUN 2023 (2023), č. článku 101269. ISSN 2451-9103. E-ISSN 2451-9103
R&D Projects: GA ČR(CZ) GA22-26590S
Institutional support: RVO:68081707
Keywords : Cancer proteins * Anterior gradient receptor * Chronopotentiometric stripping * p53 protein * Cancer biomarkers * Protein at charged surfaces
OECD category: Electrochemistry (dry cells, batteries, fuel cells, corrosion metals, electrolysis)
Impact factor: 8.5, year: 2022
Method of publishing: Limited access
https://www.sciencedirect.com/science/article/pii/S2451910323000625?via%3Dihub
Permanent Link: https://hdl.handle.net/11104/0350460 - 7.0569719 - BFÚ 2024 RIV NL eng J - Journal Article
Legartová, Soňa - Fagherazzi, Paolo - Goswami, Pratik - Brázda, Václav - Lochmanová, G. - Koutná, I. - Bártová, Eva
Irradiation potentiates p53 phosphorylation and p53 binding to the promoter and coding region of the TP53 gene.
Biochimie. Roč. 204, č. 2023 (2023), s. 154-168. ISSN 0300-9084. E-ISSN 1638-6183
Grant - others:AV ČR(CZ) StrategieAV21/7
Institutional support: RVO:68081707
Keywords : p53 * 53bp1 * DNA damage * Epigenetics * Mass spectrometry * flim-fret * afm
OECD category: Biochemistry and molecular biology
Impact factor: 3.9, year: 2022
Method of publishing: Limited access
https://www.sciencedirect.com/science/article/abs/pii/S0300908422002498?via%3Dihub
Permanent Link: https://hdl.handle.net/11104/0344343 - 8.0556576 - FGÚ 2023 RIV US eng J - Journal Article
Mandal, R. - Kohoutová, Klára - Petrvalská, Olivia - Horváth, M. - Srb, Pavel - Veverka, Václav - Obšilová, Veronika - Obšil, Tomáš
FOXO4 interacts with p53 TAD and CRD and inhibits its binding to DNA.
Protein Science. Roč. 31, č. 5 (2022), č. článku e4287. ISSN 0961-8368. E-ISSN 1469-896X
R&D Projects: GA ČR(CZ) GA21-02080S
Research Infrastructure: CIISB II - 90127
Institutional support: RVO:67985823 ; RVO:61388963
Keywords : DNA binding * forkhead box O 4 * nuclear magnetic resonance * protein-protein interaction * senescence * transcription factor p53
OECD category: Biochemistry and molecular biology
Impact factor: 8, year: 2022
Method of publishing: Limited access
https://doi.org/10.1002/pro.4287
Permanent Link: http://hdl.handle.net/11104/0330737 - 9.0552054 - FZÚ 2022 RIV US eng J - Journal Article
Yang, X.X. - Song, C. - Zhang, L. - Wang, J. - Yu, X. - Yu, B. - Zablotskii, Vitalii - Zhang, X.
An upward 9.4 T static magnetic field inhibits DNA synthesis and increases ROS-P53 to suppress lung cancer growth.
Translational Oncology. Roč. 14, č. 7 (2021), č. článku 101103. ISSN 1936-5233. E-ISSN 1936-5233
Institutional support: RVO:68378271
Keywords : 9.4 T static magnetic field * lung cancer * cell cycle * P53 * ROS
OECD category: Particles and field physics
Impact factor: 4.803, year: 2021
Method of publishing: Open access
Permanent Link: http://hdl.handle.net/11104/0327221File Download Size Commentary Version Access 0552054.pdf 1 4.4 MB CC BY-NC-ND licence Publisher’s postprint open-access - 10.0544903 - ÚMG 2022 RIV GB eng J - Journal Article
Štorchová, Radka - Burdová, Kamila - Palek, Matouš - Medema, R.H. - Macůrek, Libor
A novel assay for screening WIP1 phosphatase substrates in nuclear extracts.
FEBS Journal. Roč. 288, č. 20 (2021), s. 6035-6051. ISSN 1742-464X. E-ISSN 1742-4658
R&D Projects: GA ČR GA19-15962S; GA MŠMT LO1220; GA MŠMT LM2015063; GA MŠMT(CZ) EF18_046/0016045
Institutional support: RVO:68378050
Keywords : acetylation * phosphorylation * ppm1d * activation * p300 * acetylation * DNA damage response * p53 * protein phosphatase
OECD category: Biochemistry and molecular biology
Impact factor: 5.622, year: 2021
Method of publishing: Limited access
https://febs.onlinelibrary.wiley.com/doi/10.1111/febs.15965
Permanent Link: http://hdl.handle.net/11104/0321699