Search results
- 1.0562611 - BC 2023 RIV GB eng J - Journal Article
Duraisamy, G.S. - Jo, E. - Huvarová, I. - Park, K. H. - Heger, Z. - Adam, V. - Růžek, Daniel - Windisch, M.P. - Miller, A. D.
Selected ginsenosides interfere efficiently with hepatitis B virus mRNA expression levels and suppress viral surface antigen secretion.
Heliyon. Roč. 8, č. 9 (2022), č. článku e10465. ISSN 2405-8440. E-ISSN 2405-8440
Institutional support: RVO:60077344
Keywords : Ginsenoside * Hepatitis B virus * Lamivudine * Nucleoside/nucleotide analogues * Hepatitis B surface protein * Hepatitis B surface antigen * Chronic hepatitis B virus * Drug combinations
OECD category: Microbiology
Impact factor: 4, year: 2022
Method of publishing: Open access
https://www.sciencedirect.com/science/article/pii/S2405844022017534?via%3Dihub
Permanent Link: https://hdl.handle.net/11104/0338676 - 2.0556926 - ÚOCHB 2023 RIV CH eng J - Journal Article
Andrei, G. - Fiten, P. - Krečmerová, Marcela - Opdenakker, G. - Topalis, D. - Snoeck, R.
Poxviruses Bearing DNA Polymerase Mutations Show Complex Patterns of Cross-Resistance.
Biomedicines. Roč. 10, č. 3 (2022), č. článku 580. E-ISSN 2227-9059
R&D Projects: GA MŠMT(CZ) LM2018133
Institutional support: RVO:61388963
Keywords : vaccinia virus * DNA polymerase * drug resistance * nucleotide analogues * cidofovir * acyclic nucleoside phosphonates * phosphonoacetic acid
OECD category: Biochemistry and molecular biology
Impact factor: 4.7, year: 2022
Method of publishing: Open access
https://doi.org/10.3390/biomedicines10030580
Permanent Link: http://hdl.handle.net/11104/0331038 - 3.0545555 - ÚOCHB 2022 RIV FR eng J - Journal Article
Kalčic, Filip - Frydrych, Jan - Doleželová, Eva - Slapničková, Martina - Pachl, Petr - Poštová Slavětínská, Lenka - Dračínský, Martin - Hocková, Dana - Zíková, Alena - Janeba, Zlatko
C1′-Branched acyclic nucleoside phosphonates mimicking adenosine monophosphate: Potent inhibitors of Trypanosoma brucei adenine phosphoribosyltransferase.
European Journal of Medicinal Chemistry. Roč. 225, Dec 5 (2021), č. článku 113798. ISSN 0223-5234. E-ISSN 1768-3254
R&D Projects: GA MŠMT(CZ) EF16_019/0000759; GA ČR(CZ) GA19-07707S
Institutional support: RVO:61388963 ; RVO:60077344
Keywords : trypanosomiasis * purine salvage pathway * APRT * nucleotide analogues * phosphonates * enzyme inhibitors
OECD category: Organic chemistry; Microbiology (BC-A)
Impact factor: 7.088, year: 2021
Method of publishing: Limited access
https://doi.org/10.1016/j.ejmech.2021.113798
Permanent Link: http://hdl.handle.net/11104/0322237 - 4.0519289 - ÚOCHB 2020 US eng A - Abstract
Procházková, Eliška - Navrátil, R. - Janeba, Zlatko - Roithová, J. - Baszczyňski, O.
ProTide Activation Pathway: Trapping the Reactive Cyclic Phosphorus Intermediates.
32nd International Conference on Antiviral Research (ICAR). Baltimore: International Society for Antiviral Research, 2019. s. 75.
[International Conference on Antiviral Research (ICAR) /32./. 12.05.2019-15.05.2019, Baltimore]
Grant - others:AV ČR(CZ) L200551701
Institutional support: RVO:61388963
Keywords : nucleotide analogues * ProTide activation
OECD category: Organic chemistry
Permanent Link: http://hdl.handle.net/11104/0304285 - 5.0518502 - ÚOCHB 2020 CZ eng A - Abstract
Hocková, Dana - Doleželová, Eva - Terán, D. - Špaček, Petr - Česnek, Michal - Gahura, Ondřej - Kotrbová, Zuzana - Keough, D. T. - Zíková, Alena - Guddat, L. W.
Acyclic nucleoside phosphonates as inhibitors of Trypanosoma brucei 6-oxopurine phosphoribosyltransferases.
Liblice 2019. 54th Advances in Organic, Bioorganic and Pharmaceutical Chemistry. Praha: Czech Chemical Society, 2019. s. 89.
[Liblice 2019. Advances in Organic, Bioorganic and Pharmaceutical Chemistry /54./. 06.11.2019-08.11.2019, Špindlerův Mlýn]
R&D Projects: GA ČR(CZ) GA16-06049S; GA MŠMT(CZ) LL1205
Institutional support: RVO:61388963 ; RVO:60077344
Keywords : nucleotide analogues * enzyme inhibitors * HG(X)PRT
OECD category: Organic chemistry
Permanent Link: http://hdl.handle.net/11104/0303896 - 6.0518500 - ÚOCHB 2020 CZ eng A - Abstract
Klejch, Tomáš - Keough, D. T. - Travis, J. - Janeba, Zlatko - Guddat, L. W. - Hocková, Dana
Alkene Approach to Acyclic Nucleoside Phosphonates: Inhibitors of 6-Oxopurine Phosphoribosyltransferases.
Liblice 2019. 54th Advances in Organic, Bioorganic and Pharmaceutical Chemistry. Praha: Czech Chemical Society, 2019. s. 79.
[Liblice 2019. Advances in Organic, Bioorganic and Pharmaceutical Chemistry /54./. 06.11.2019-08.11.2019, Špindlerův Mlýn]
R&D Projects: GA ČR(CZ) GA16-06049S
Institutional support: RVO:61388963
Keywords : nucleotide analogues * enzyme inhibitors * HG(X)PRT
OECD category: Organic chemistry
Permanent Link: http://hdl.handle.net/11104/0303892 - 7.0518497 - ÚOCHB 2020 TH eng A - Abstract
Hocková, Dana - Zíková, Alena - Keough, D. T. - Guddat, L. W.
Modular synthesis of N-branched acyclic nucleoside phosphonates (aza-ANPs) designed as inhibitors of 6-oxopurine phosphoribosyltransferases.
20th Tetrahedron Symposium. Bangkok: Elsevier, 2019. P1.104, „P1014“.
[Tetrahedron Symposium /20./. 18.06.2019-21.06.2019, Bangkok]
Institutional support: RVO:61388963 ; RVO:60077344
Keywords : nucleotide analogues * enzyme inhibitors * HG(X)PRT
OECD category: Organic chemistry
Permanent Link: http://hdl.handle.net/11104/0303883 - 8.0509500 - ÚOCHB 2020 RIV DE eng J - Journal Article
Blindauer, C. A. - Holý, Antonín - Operschall, B. P. - Sigel, A. - Song, B. - Sigel, H.
Metal Ion-Coordinating Properties in Aqueous Solutions of the Antivirally Active Nucleotide Analogue (S)-9-[3-Hydroxy-2-(phosphonomethoxy)propyl]adenine (HPMPA) - Quantification of Complex Isomeric Equilibria.
European Journal of Inorganic Chemistry. Roč. 2019, č. 35 (2019), s. 3892-3903. ISSN 1434-1948. E-ISSN 1099-0682
Institutional support: RVO:61388963
Keywords : acyclic nucleoside phosphonates * antiviral agents * isomeric equilibria * coordination modes * nucleotide analogues
OECD category: Organic chemistry
Impact factor: 2.529, year: 2019
Method of publishing: Limited access
https://onlinelibrary.wiley.com/doi/abs/10.1002/ejic.201900620
Permanent Link: http://hdl.handle.net/11104/0300238 - 9.0500128 - ÚOCHB 2019 JP eng A - Abstract
Hocková, Dana - Zíková, Alena - Keough, D. T. - Guddat, L. W.
Modular Synthesis of N-Branched Acyclic Nucleoside Phosphonates (aza-ANPs) Designed as Inhibitors of 6-Oxopurine Phosphoribosyltransferases.
IKCOC-14. 14th International Kyoto Conference on New Aspects of Organic Chemistry. Kyoto: Kyoto University, 2018. s. 80.
[IKCOC-14. International Kyoto Conference on New Aspects of Organic Chemistry /14./. 12.11.2018-16.11.2018, Kyoto]
R&D Projects: GA ČR(CZ) GA16-06049S
Institutional support: RVO:61388963 ; RVO:60077344
Keywords : nucleotide analogues * enzyme inhibitors * HG(X)PRT
OECD category: Organic chemistry
Permanent Link: http://hdl.handle.net/11104/0292312 - 10.0500089 - ÚOCHB 2019 CZ eng A - Abstract
Klejch, Tomáš - Keough, D. T. - Sun, M. - Janeba, Zlatko - Guddat, L. W. - Hocková, Dana
Sulfur Bridged Acyclic Nucleoside Phosphonates as Potential Inhibitors of 6-Oxopurine Phosphoribosyltransferases.
Liblice 2018. 53rd Advances in Organic, Bioorganic and Pharmaceutical Chemistry. Praha: Czech Chemical Society, 2018. s. 91.
[Liblice 2018. Advances in Organic, Bioorganic and Pharmaceutical Chemistry /53./. 02.11.2018-04.11.2018, Lázně Bělohrad]
R&D Projects: GA ČR(CZ) GA16-06049S
Institutional support: RVO:61388963
Keywords : nucleotide analogues * enzyme inhibitors * HG(X)PRT * sulfur oxidation
OECD category: Organic chemistry
Permanent Link: http://hdl.handle.net/11104/0292307