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- 1.0580809 - ÚOCHB 2024 RIV CZ cze J - Journal Article
Bouřa, Evžen
Strukturní biologie v antivirovém výzkumu na příbězích kinas lipidů, proteinu STING a virových methyltransferas.
[Structural Biology in Antiviral Research – A Story Illustrated by the Tales of Lipid Kinases, STING and Viral Methyltransferases.]
Chemické listy. Roč. 117, č. 12 (2023), s. 755-763. ISSN 0009-2770. E-ISSN 1213-7103
R&D Projects: GA MŠMT(CZ) LX22NPO5103
Institutional support: RVO:61388963
Keywords : antivirals * lipid kinase * STING * methyltransferase * virus
OECD category: Virology
Impact factor: 0.6, year: 2022
Method of publishing: Open access
https://doi.org/10.54779/chl20230755
Permanent Link: https://hdl.handle.net/11104/0349574File Download Size Commentary Version Access 10.54779chl20230755.pdf 0 1.5 MB Publisher’s postprint open-access - 2.0576137 - ÚOCHB 2024 RIV US eng J - Journal Article
Inniss, N. L. - Kozic, Ján - Li, F. - Rosas-Lemus, M. - Minasov, G. - Rybáček, Jiří - Zhu, Y. - Pohl, Radek - Shuvalova, L. - Rulíšek, Lubomír - Brunzelle, J. S. - Bednárová, Lucie - Štefek, Milan - Kormaník, Ján Michael - Andris, Erik - Šebestík, Jaroslav - Li, A. S. M. - Brown, P. J. - Schmitz, U. - Saikatendu, K. - Chang, E. - Nencka, Radim - Vedadi, M. - Satchell, K. J. F.
Discovery of a Druggable, Cryptic Pocket in SARS-CoV-2 nsp16 Using Allosteric Inhibitors.
ACS Infectious Diseases. Roč. 9, č. 10 (2023), s. 1918-1931. ISSN 2373-8227
R&D Projects: GA MŠMT(CZ) EF16_019/0000729; GA MZd(CZ) NU20-05-00472
Institutional support: RVO:61388963
Keywords : coronavirus * NSP16 methyltransferase * covalent inhibitors * structural biology * antiviral
OECD category: Virology
Impact factor: 5.3, year: 2022
Method of publishing: Limited access
https://doi.org/10.1021/acsinfecdis.3c00203
Permanent Link: https://hdl.handle.net/11104/0345731 - 3.0574061 - ÚOCHB 2024 RIV NL eng J - Journal Article
Škvára, Petr - Chalupská, Dominika - Klíma, Martin - Kozic, Ján - Šilhán, Jan - Bouřa, Evžen
Structural basis for RNA-cap recognition and methylation by the mpox methyltransferase VP39.
Antiviral Research. Roč. 216, August (2023), č. článku 105663. ISSN 0166-3542. E-ISSN 1872-9096
R&D Projects: GA MŠMT(CZ) LX22NPO5103
Institutional support: RVO:61388963
Keywords : messenger-RNA * virus methyltransferase
OECD category: Virology
Impact factor: 7.6, year: 2022
Method of publishing: Open access
https://doi.org/10.1016/j.antiviral.2023.105663
Permanent Link: https://hdl.handle.net/11104/0344428File Download Size Commentary Version Access 10.1016j.antiviral.2023.105663.pdf 1 3 MB Publisher’s postprint open-access
Research data: PDB - 4.0569149 - ÚOCHB 2024 RIV NL eng J - Journal Article
Li, F. - Ghiabi, P. - Hajian, T. - Klíma, Martin - Li, A. S. M. - Yazdi, A. K. - Chau, I. - Loppnau, P. - Kutera, M. - Seitova, A. - Bolotokova, A. - Hutchinson, A. - Perveen, S. - Bouřa, Evžen - Vedadi, M.
SS148 and WZ16 inhibit the activities of nsp10-nsp16 complexes from all seven human pathogenic coronaviruses.
Biochimica et Biophysica Acta-General Subjects. Roč. 1867, č. 4 (2023), č. článku 130319. ISSN 0304-4165. E-ISSN 1872-8006
R&D Projects: GA MŠMT(CZ) EF16_019/0000729
Institutional support: RVO:61388963
Keywords : RNA methyltransferase * viral protein * enzyme purification * enzyme kinetics * RNA virus * nsp10-nsp16 complex * coronavirus
OECD category: Biochemistry and molecular biology
Impact factor: 3, year: 2022
Method of publishing: Open access
https://doi.org/10.1016/j.bbagen.2023.130319
Permanent Link: https://hdl.handle.net/11104/0340473 - 5.0568951 - BTÚ 2024 RIV US eng J - Journal Article
Oh, S. - Jo, S. - Kim, H. S. - Mai, V. - Endaya, B. - Neužil, Jiří - Jung, K. H. - Hong, S. - Kim, J. - Park, S.
Chemical Biopsy for GNMT as Noninvasive and Tumorigenesis-Relevant Diagnosis of Liver Cancer.
Analytical Chemistry. Roč. 95, č. 2 (2023), s. 1184-1192. ISSN 0003-2700. E-ISSN 1520-6882
Institutional support: RVO:86652036
Keywords : GLYCINE N-METHYLTRANSFERASE * INFILTRATIVE HEPATOCELLULAR-CARCINOMA * FOLATE-BINDING-PROTEIN
OECD category: Analytical chemistry
Impact factor: 7.4, year: 2022
Method of publishing: Limited access
https://pubs.acs.org/doi/full/10.1021/acs.analchem.2c03944
Permanent Link: https://hdl.handle.net/11104/0347904 - 6.0567310 - ÚOCHB 2023 RIV CZ eng A - Abstract
Bouřa, Evžen
Structural and functional studies of coronaviral RNA-methyltransferases.
Czech Chemical Society Symposium Series. Roč. 20, č. 6 (2022), s. 352-352. ISSN 2336-7202.
[Annual meeting of the National Institute of Virology and Bacteriology (NIVB) /1./. 30.11.2022-02.12.2022, Kutná Hora]
R&D Projects: GA MŠMT(CZ) LX22NPO5103
Institutional support: RVO:61388963
Keywords : RNA-methyltransferase * antiviral * coronavirus
OECD category: Virology
http://www.ccsss.cz/index.php/ccsss/issue/view/37/67
Permanent Link: https://hdl.handle.net/11104/0338570File Download Size Commentary Version Access L-06 UOCHB_Boura.pdf 3 186.7 KB Publisher’s postprint open-access - 7.0567306 - ÚOCHB 2023 RIV CZ eng A - Abstract
Nencka, Radim - Otava, Tomáš - Krafčíková, Petra - Klíma, Martin - Li, F. - Eyer, Luděk - Devkota, K. - Perveen, S. - Dejmek, Milan - Šála, Michal - Allan, Anthony - Štefek, Milan - Vedadi, M. - Růžek, Daniel - Bouřa, Evžen
Exploring non-traditional targets for antiviral therapy – novel inhibitors of viral methyltransferases.
Czech Chemical Society Symposium Series. Roč. 20, č. 6 (2022), s. 349-349. ISSN 2336-7202.
[Annual meeting of the National Institute of Virology and Bacteriology (NIVB) /1./. 30.11.2022-02.12.2022, Kutná Hora]
R&D Projects: GA MŠMT(CZ) LX22NPO5103
Institutional support: RVO:61388963 ; RVO:60077344
Keywords : methyltransferase * antiviral * RNA viruses
OECD category: Virology
http://www.ccsss.cz/index.php/ccsss/issue/view/37/67
Permanent Link: https://hdl.handle.net/11104/0338566File Download Size Commentary Version Access L-03 UOCHB_Nencka.pdf 2 89.2 KB Publisher’s postprint open-access - 8.0553668 - BFÚ 2022 RIV CH eng J - Journal Article
Stixová, Lenka - Komůrková, Denisa - Kovaříková, Alena - Fagherazzi, Paolo - Bártová, Eva
Localization of METTL16 at the Nuclear Periphery and the Nucleolus Is Cell Cycle-Specific and METTL16 Interacts with Several Nucleolar Proteins.
Life. Roč. 11, č. 7 (2021), č. článku 669. E-ISSN 2075-1729
Grant - others:AV ČR(CZ) StrategieAV21/7
Program: StrategieAV
Institutional support: RVO:68081707
Keywords : m(6)a methyltransferase * rna * methylation * substrate
OECD category: Microbiology
Impact factor: 3.253, year: 2021
Method of publishing: Open access
https://www.mdpi.com/2075-1729/11/7/669/htm
Permanent Link: http://hdl.handle.net/11104/0328417 - 9.0544643 - ÚOCHB 2022 RIV CH eng J - Journal Article
Horová, Vladimíra - Landová, Barbora - Hodek, Jan - Chalupský, Karel - Krafčíková, Petra - Chalupská, Dominika - Duchoslav, Vojtěch - Weber, Jan - Bouřa, Evžen - Klíma, Martin
Localization of SARS-CoV-2 Capping Enzymes Revealed by an Antibody against the nsp10 Subunit.
Viruses. Roč. 13, č. 8 (2021), č. článku 1487. E-ISSN 1999-4915
R&D Projects: GA MŠMT(CZ) EF16_019/0000729; GA ČR(CZ) GA21-25280S
Institutional support: RVO:61388963
Keywords : coronavirus * SARS-CoV-2 * methyltransferase * nsp10 * nsp16 * nsp14 * capping enzyme
OECD category: Virology
Impact factor: 5.818, year: 2021
Method of publishing: Open access
https://doi.org/10.3390/v13081487
Permanent Link: http://hdl.handle.net/11104/0321475 - 10.0544555 - ÚOCHB 2022 RIV US eng J - Journal Article
Otava, Tomáš - Šála, Michal - Li, F. - Fanfrlík, Jindřich - Devkota, K. - Perveen, S. - Chau, I. - Pakarian, P. - Hobza, Pavel - Vedadi, M. - Bouřa, Evžen - Nencka, Radim
The Structure-Based Design of SARS-CoV-2 nsp14 Methyltransferase Ligands Yields Nanomolar Inhibitors.
ACS Infectious Diseases. Roč. 7, č. 8 (2021), s. 2214-2220. ISSN 2373-8227
R&D Projects: GA MŠMT(CZ) EF16_019/0000729; GA MZd(CZ) NU20-05-00472
Institutional support: RVO:61388963
Keywords : COVID-19 * SARS-CoV-2 * methyltransferase * nsp14 nsp10 * structure-based design * inhibitors
OECD category: Microbiology
Impact factor: 5.578, year: 2021
Method of publishing: Limited access
https://doi.org/10.1021/acsinfecdis.1c00131
Permanent Link: http://hdl.handle.net/11104/0321402