Search results
- 1.0580041 - ÚOCHB 2024 RIV eng P - Patent Document
Slusher, B. - Rais, R. - Riggins, G. - Majer, Pavel - Tichý, Tomáš - Vávra, Jan - Jančařík, Andrej - Tenora, Lukáš
Mebendazole prodrugs with enhanced solubility and oral bioavailability.
2023. Owner: The Johns Hopkins University - Ústav organické chemie a biochemie AV ČR, v. v. i. Date of the patent acceptance: 14.09.2023. Patent Number: AU2019216757. Territorial Protection: národní patent v zemi mimo EU ,mezinárodní patentová ochrana dle Smlouvy o patentové spolupráci.
Institutional support: RVO:61388963
Keywords : mebendazole * prodrug * oral bioavailability
OECD category: Medicinal chemistry
https://worldwide.espacenet.com/patent/search/family/067549070/publication/AU2019216757B2?q=AU2019216757B2
Permanent Link: https://hdl.handle.net/11104/0348822 - 2.0577575 - ÚOCHB 2024 RIV eng P - Patent Document
Slusher, B. - Rais, R. - Riggins, G. - Majer, Pavel - Tichý, Tomáš - Vávra, Jan - Jančařík, Andrej - Tenora, Lukáš
Mebendazole prodrugs with enhanced solubility and oral bioavailability.
2023. Owner: The Johns Hopkins University - Ústav organické chemie a biochemie AV ČR, v. v. i. Date of the patent acceptance: 01.08.2023. Patent Number: US11712435. Territorial Protection: národní patent v zemi mimo EU ,mezinárodní patentová ochrana dle Smlouvy o patentové spolupráci.
Institutional support: RVO:61388963
Keywords : mebendazole * prodrug * oral bioavailability
OECD category: Medicinal chemistry
https://worldwide.espacenet.com/patent/search/family/067549070/publication/US11712435B2?q=US11712435B2
Permanent Link: https://hdl.handle.net/11104/0346694 - 3.0558143 - ÚMCH 2023 RIV CH eng J - Journal Article
Studenovský, Martin - Rumlerová, Anna - Kovářová, Jiřina - Dvořáková, Barbora - Sivák, Ladislav - Kostka, Libor - Berdár, Daniel - Etrych, Tomáš - Kovář, Marek
HPMA copolymer mebendazole conjugate allows systemic administration and possesses antitumour activity in vivo.
Pharmaceutics. Roč. 14, č. 6 (2022), č. článku 1201. E-ISSN 1999-4923
R&D Projects: GA ČR(CZ) GA19-05649S; GA MŠMT(CZ) LTAUSA18083
Grant - others:AV ČR(CZ) JSPS-22-01
Program: Bilaterální spolupráce
Institutional support: RVO:61389013 ; RVO:61388971
Keywords : mebendazole * drug delivery * cancer therapy
OECD category: Polymer science; Pharmacology and pharmacy (MBU-M)
Impact factor: 5.4, year: 2022
Method of publishing: Open access
https://www.mdpi.com/1999-4923/14/6/1201
Permanent Link: https://hdl.handle.net/11104/0333076 - 4.0553327 - ÚACH 2023 RIV GB eng J - Journal Article
Bogucka-Kocka, A. - Kolodziej, P. - Makuch-Kocka, A. - Rozycka, D. - Rykowski, S. - Nekvinda, Jan - Grüner, Bohumír - Olejniczak, A.
Nematicidal activity of naphthalimide-boron cluster conjugates.
Chemical Communications. Roč. 58, č. 15 (2022), s. 2528-2531. ISSN 1359-7345. E-ISSN 1364-548X
R&D Projects: GA ČR(CZ) GA21-14409S
Institutional support: RVO:61388980
Keywords : in-vitro * drug * anticancer * albendazole * mebendazole * pharmacophores * lipophilicity * resistance
OECD category: Inorganic and nuclear chemistry
Impact factor: 4.9, year: 2022
Method of publishing: Limited access
https://doi.org/10.1039/D1CC07075D
Permanent Link: http://hdl.handle.net/11104/0328285 - 5.0545100 - ÚMCH 2022 RIV CH eng J - Journal Article
Studenovský, Martin - Rumlerová, Anna - Kostka, Libor - Etrych, Tomáš
HPMA-based polymer conjugates for repurposed drug mebendazole and other imidazole-based therapeutics.
Polymers. Roč. 13, č. 15 (2021), č. článku 2530. E-ISSN 2073-4360
R&D Projects: GA ČR(CZ) GA19-01417S; GA ČR(CZ) GA19-05649S; GA MŠMT(CZ) LTAUSA18083
Institutional support: RVO:61389013
Keywords : mebendazole * drug delivery * drug repurposing
OECD category: Polymer science
Impact factor: 4.967, year: 2021
Method of publishing: Open access
https://www.mdpi.com/2073-4360/13/15/2530
Permanent Link: http://hdl.handle.net/11104/0321902 - 6.0490659 - ÚOCHB 2019 RIV US eng J - Journal Article
Zimmermann, S. C. - Tichý, Tomáš - Vávra, Jan - Dash, R. P. - Slusher, C. E. - Gadiano, A. J. - Wu, Y. - Jančařík, Andrej - Tenora, Lukáš - Monincová, Lenka - Prchalová, E. - Riggins, G. J. - Majer, Pavel - Slusher, B. S. - Rais, R.
N-Substituted Prodrugs of Mebendazole Provide Improved Aqueous Solubility and Oral Bioavailability in Mice and Dogs.
Journal of Medicinal Chemistry. Roč. 61, č. 9 (2018), s. 3918-3929. ISSN 0022-2623. E-ISSN 1520-4804
Institutional support: RVO:61388963
Keywords : anthelmintic drug mebendazole * water soluble prodrugs * in vivo
OECD category: Organic chemistry
Impact factor: 6.054, year: 2018
Permanent Link: http://hdl.handle.net/11104/0284815 - 7.0330803 - FGÚ 2010 RIV SK eng J - Journal Article
Tolstoy, V.A. - Lytvynets, Andrej - Langrová, I.
Increasing antioxidant protection during mebendazole and AKβ vitamin complex treatment of experimental trichinellosis in rats.
[Zvýšení antioxidantní ochrany u potkanů s experimentální trichinelózou během léčení mebendazolem a AKβ vitaminovým komplexem.]
Helminthologia. Roč. 46, č. 3 (2009), s. 145-150. ISSN 0440-6605. E-ISSN 1336-9083
Institutional research plan: CEZ:AV0Z50110509
Keywords : AKβ vitamin complex * lipid peroxidation process * mebendazole * Trichinella spiralis
Subject RIV: FP - Other Medical Disciplines
Impact factor: 0.951, year: 2009
Permanent Link: http://hdl.handle.net/11104/0176503 - 8.0306020 - FGÚ 2008 RIV DE eng J - Journal Article
Tolstoj, V. A. - Lytvynets, Andrej - Langrová, I.
Pro-oxidant effects of Mebendazole in albino rats experimentally infected with Trichinella spiralis.
[Pro-oxidační efekt při použiti mebendazolu u potkanů experimentálně infikovaných Trichinella spiralis.]
Parasitology Research. Roč. 100, č. 6 (2007), s. 1277-1280. ISSN 0932-0113. E-ISSN 1432-1955
Institutional research plan: CEZ:AV0Z50110509
Keywords : lipid peroxidation process * Mebendazole * Trichinella spiralis
Subject RIV: CE - Biochemistry
Impact factor: 1.512, year: 2007
Permanent Link: http://hdl.handle.net/11104/0159127