Search results
- 1.0586251 - BTÚ 2025 RIV CH eng J - Journal Article
Liatsou, I. - Assefa, B. - Liyanage, W. - Surasinghe, S. - Nováková, Zora - Bařinka, Cyril - Gabrielson, K. - Raman, V. - Artemov, D. - Hapuarachchige, S.
Development and therapeutic evaluation of 5D3(CC-MLN8237)3.2 antibody-theranostic conjugates for PSMA-positive prostate cancer therapy
.
Frontiers in Pharmacology. Roč. 15, MAY 1 2024 (2024), č. článku 1385598. ISSN 1663-9812. E-ISSN 1663-9812
Institutional support: RVO:86652036
Keywords : aurora kinase inhibitors * small-molecule inhibitor * membrane antigen psma * cell-cycle arrest * alisertib mln8237
OECD category: Pharmacology and pharmacy
Impact factor: 4.4, year: 2023
Method of publishing: Limited access
https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2024.1385598/full
Permanent Link: https://hdl.handle.net/11104/0354934 - 2.0531622 - ÚŽFG 2020 RIV eng P - Patent Document
Kollaredy, M. R. N. - Hajdúch, M. - Dzubak, P. - Srovnal, J. - Hrabáková, Rita - Kovářová, Hana
Method of determination of cancer cell drug sensitivity towards Aurora kinase inhibitors and overcoming their resistance.
2017. Owner: Palacky University Olomouc, Institute of Animal Physiology and Genetics, CAS. Date of the patent acceptance: 07.06.2017. Patent Number: JP6144696
R&D Projects: GA MŠMT(CZ) LO1609
Institutional support: RVO:67985904
Keywords : Aurora kinase inhibitors
OECD category: Cell biology
https://worldwide.espacenet.com/publicationDetails/biblio?CC=JP&NR=6144696B2&KC=B2&FT=D&ND=4&date=20170607&DB=&locale=en_EP#
Permanent Link: http://hdl.handle.net/11104/0310249 - 3.0531620 - ÚŽFG 2020 RIV eng P - Patent Document
Kollaredy, M. R. N. - Hajdúch, M. - Dzubak, P. - Srovnal, J. - Hrabáková, Rita - Kovářová, Hana
Method of determination of cancer cell drug sensitivity towards aurora kinase inhibitors.
2016. Owner: Palacký University Olomouc, Institute of Animal Physiology and Genetics CAS. Date of the patent acceptance: 17.08.2016. Patent Number: EP2788504
R&D Projects: GA MŠMT(CZ) LO1609
Institutional support: RVO:67985904
Keywords : aurora kinase inhibitors
OECD category: Cell biology
https://worldwide.espacenet.com/publicationDetails/originalDocument?FT=D&date=20160817&DB=&locale=en_EP&CC=EP&NR=2788504B1&KC=B1&ND=4#
Permanent Link: http://hdl.handle.net/11104/0310248 - 4.0498520 - ÚOCHB 2019 RIV US eng J - Journal Article
Tokarenko, Anna - Lišková, B. - Smolen, Sabina - Táborská, N. - Tichý, Michal - Gurská, S. - Perlíková, Pavla - Frydrych, I. - Tloušťová, Eva - Znojek, P. - Mertlíková-Kaiserová, Helena - Poštová Slavětínská, Lenka - Pohl, Radek - Klepetářová, Blanka - Khalid, N. U. A. - Wenren, Y. - Laposa, R. R. - Džubák, P. - Hajdúch, M. - Hocek, Michal
Synthesis and Cytotoxic and Antiviral Profiling of Pyrrolo- and Furo-Fused 7-Deazapurine Ribonucleosides.
Journal of Medicinal Chemistry. Roč. 61, č. 20 (2018), s. 9347-9359. ISSN 0022-2623. E-ISSN 1520-4804
R&D Projects: GA ČR(CZ) GA16-00178S; GA TA ČR(CZ) TE01020028; GA MŠMT(CZ) LO1304; GA MŠMT(CZ) LM2015064
Grant - others:AV ČR(CZ) AP1501
Program: Akademická prémie - Praemium Academiae
Institutional support: RVO:61388963
Keywords : hepatitis C virus * adenosine kinase inhibitors * mitochondrial RNA polymerase
OECD category: Organic chemistry
Impact factor: 6.054, year: 2018
https://pubs.acs.org/doi/full/10.1021/acs.jmedchem.8b01258
Permanent Link: http://hdl.handle.net/11104/0291128File Download Size Commentary Version Access 0498520.pdf 9 1.9 MB Publisher’s postprint open-access - 5.0483285 - ÚMG 2018 RIV GB eng J - Journal Article
Klein, O. - Ngo-Nyekel, F. - Stefanache, T. - Torres, R. - Salomonsson, M. - Hallgren, J. - Radinger, M. - Bambousková, Monika - Campbell, M. - Cohen-Mor, S. - Dema, B. - Rose, C.G. - Abrink, M. - Charles, N. - Ainooson, G. - Paivandy, A. - Pavlova, V.G. - Serrano-Candelas, E. - Yu, Y. - Hellman, L. - Jensen, B.M. - Van Anrooij, B. - Grootens, J. - Gura, H.K. - Stylianou, M. - Tobio, A. - Blank, U. - Ohrvik, H. - Maurer, M.
Identification of Biological and Pharmaceutical Mast Cell- and Basophil-Related Targets.
Scandinavian Journal of Immunology. Roč. 83, č. 6 (2016), s. 465-472. ISSN 0300-9475. E-ISSN 1365-3083
Institutional support: RVO:68378050
Keywords : tyrosine kinase inhibitors * fc-epsilon-ri * in-vivo * inflammatory diseases * dependent activation * midostaurin pkc412 * mediator release * murine basophils * animal-models * mouse models
OECD category: Immunology
Impact factor: 2.256, year: 2016
Permanent Link: http://hdl.handle.net/11104/0281310 - 6.0482957 - ÚEB 2018 RIV GB eng J - Journal Article
Malínková, Veronika - Řezníčková, Eva - Jorda, Radek - Gucký, T. - Kryštof, Vladimír
Trisubstituted purine inhibitors of PDGFR alpha and their antileukemic activity in the human eosinophilic cell line EOL-1.
Bioorganic & Medicinal Chemistry. Roč. 25, č. 24 (2017), s. 6523-6535. ISSN 0968-0896. E-ISSN 1464-3391
R&D Projects: GA MŠMT(CZ) LO1204
Institutional support: RVO:61389030
Keywords : dependent kinase inhibitors * src tyrosine kinase * 2,6,9-trisubstituted purines * therapeutic target * potent inhibitor * imatinib * leukemia * mutations * mutant * domain
OECD category: Hematology
Impact factor: 2.881, year: 2017
Permanent Link: http://hdl.handle.net/11104/0278331File Download Size Commentary Version Access 2017_Malinkova_Bioorganic & medicinal chemistry_6523.pdf 1 1.1 MB Other open-access - 7.0475217 - ÚOCHB 2018 RIV US eng J - Journal Article
Tichý, Michal - Smolen, Sabina - Tloušťová, Eva - Pohl, Radek - Oždian, T. - Hejtmánková, K. - Lišková, B. - Gurská, S. - Džubák, P. - Hajdúch, M. - Hocek, Michal
Synthesis and Cytostatic and Antiviral Profiling of Thieno-Fused 7-Deazapurine Ribonucleosides.
Journal of Medicinal Chemistry. Roč. 60, č. 6 (2017), s. 2411-2424. ISSN 0022-2623. E-ISSN 1520-4804
R&D Projects: GA ČR(CZ) GA16-00178S; GA TA ČR(CZ) TE01020028; GA MŠMT(CZ) LO1304
Institutional support: RVO:61388963
Keywords : adenosine kinase inhibitors * cross-coupling reactions * cytotoxic nucleoside analogs
OECD category: Organic chemistry
Impact factor: 6.253, year: 2017
http://pubs.acs.org/doi/full/10.1021/acs.jmedchem.6b01766
Permanent Link: http://hdl.handle.net/11104/0272060File Download Size Commentary Version Access 0475217.pdf 5 1.1 MB Publisher’s postprint open-access - 8.0459008 - ÚEB 2017 RIV FR eng J - Journal Article
Baltus, C.B. - Jorda, Radek - Marot, Ch. - Berka, K. - Bazgier, Václav - Kryštof, Vladimír - Prie, G. - Viaud-Massuard, M.C.
Synthesis, biological evaluation and molecular modeling of a novel series of 7-azaindole based tri-heterocyclic compounds as potent CDK2/Cyclin E inhibitors.
European Journal of Medicinal Chemistry. Roč. 108, JAN 27 (2016), s. 701-719. ISSN 0223-5234. E-ISSN 1768-3254
R&D Projects: GA MŠMT(CZ) LO1204
Institutional support: RVO:61389030
Keywords : Cyclin-dependent kinase 2 * Kinase inhibitors * Anti-tumor agent
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 4.519, year: 2016
Permanent Link: http://hdl.handle.net/11104/0259205File Download Size Commentary Version Access 2016_Baltus_EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY_701.pdf 2 1.9 MB Other open-access - 9.0429983 - ÚEB 2015 RIV US eng J - Journal Article
Holčáková, J. - Müller, P. - Tomasec, P. - Hrstka, R. - Nekulová, M. - Kryštof, Vladimír - Strnad, Miroslav - Wilkinson, G. W. G. - Vojtěšek, B.
Inhibition of Post-Transcriptional RNA Processing by CDK Inhibitors and Its Implication in Anti-Viral Therapy.
PLoS ONE. Roč. 9, č. 2 (2014). ISSN 1932-6203. E-ISSN 1932-6203
R&D Projects: GA ČR GBP206/12/G151
Institutional support: RVO:61389030
Keywords : IMMUNODEFICIENCY-VIRUS TYPE-1 * DEPENDENT KINASE INHIBITORS * LARGE T-ANTIGEN
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 3.234, year: 2014
Permanent Link: http://hdl.handle.net/11104/0234927File Download Size Commentary Version Access 2014_Holcakova_PLOS ONE_.pdf 1 1.6 MB Other open-access - 10.0427678 - ÚOCHB 2015 RIV US eng J - Journal Article
Nauš, Petr - Caletková, Olga - Konečný, P. - Džubák, P. - Bogdanová, K. - Kolář, M. - Vrbková, J. - Slavětínská, Lenka - Tloušťová, Eva - Perlíková, Pavla - Hajdúch, M. - Hocek, Michal
Synthesis, Cytostatic, Antimicrobial, and Anti-HCV Activity of 6-Substituted 7-(Het)aryl-7-deazapurine Ribonucleosides.
Journal of Medicinal Chemistry. Roč. 57, č. 3 (2014), s. 1097-1110. ISSN 0022-2623. E-ISSN 1520-4804
R&D Projects: GA ČR GAP207/11/0344; GA TA ČR(CZ) TE01020028
Grant - others:Operational Programme Research and Development for Innovations(XE) CZ.1.05/2.1.00/01.0030
Institutional support: RVO:61388963
Keywords : adenosine-kinase-inhibitors * cross-coupling reactions * cytotoxic nucleoside analogs
Subject RIV: CC - Organic Chemistry
Impact factor: 5.447, year: 2014
Permanent Link: http://hdl.handle.net/11104/0233200