Search results
- 1.0586126 - MBÚ 2025 RIV NL eng J - Journal Article
Weber, P. - Bojarová, Pavla - Brouzdová, Jitka - Křen, Vladimír - Kulik, Natalia - Stütz, A.E. - Thonhofer, M. - Wrodnigg, T.M.
Diaminocyclopentane – l-Lysine Adducts: Potent and selective inhibitors of human O-GlcNAcase.
Bioorganic Chemistry. Roč. 148, July 2024 (2024), č. článku 107452. ISSN 0045-2068. E-ISSN 1090-2120
R&D Projects: GA ČR(CZ) GF21-01948L; GA MŠMT(CZ) EH22_008/0004597
Research Infrastructure: e-INFRA CZ - 90140; CERIT-SC - 90085; CESNET II - 90042
Institutional support: RVO:61388971
Keywords : Glycosidase * Inhibition * Inhibition * O-GlcNAcase * Hexosaminidase * Diaminocyclopentane * Tau protein * Alzheimer’s disease
OECD category: Biochemistry and molecular biology
Impact factor: 5.1, year: 2022
Method of publishing: Open access
https://www.sciencedirect.com/science/article/pii/S0045206824003572
Permanent Link: https://hdl.handle.net/11104/0353722File Download Size Commentary Version Access Diaminocyclopentane – l-Lysine Adducts.pdf 0 7.4 MB Publisher’s postprint open-access - 2.0585623 - ÚEB 2025 RIV CH eng J - Journal Article
Smolko, A. - Repar, J. - Matković, F. - Pavlović, Iva - Pěnčík, Aleš - Novák, Ondřej - Ludwig-Müller, J. - Salopek-Sondi, B.
Application of Long-Chained Auxin Conjugates Influenced Auxin Metabolism and Transcriptome Response in Brassica rapa L. ssp. pekinensis.
International Journal of Molecular Sciences. Roč. 25, č. 1 (2024), č. článku 447. ISSN 1661-6596
R&D Projects: GA MŠMT(CZ) EF16_019/0000827
Institutional support: RVO:61389030
Keywords : amino acid auxin conjugates * auxin metabolome * Brassica rapa * indole-3-acetic acid * indole-3-butyric acid * indole-3-propionic acid * root growth inhibition * transcriptome
OECD category: Biochemistry and molecular biology
Impact factor: 5.6, year: 2022
Method of publishing: Open access
https://doi.org/10.3390/ijms25010447
Permanent Link: https://hdl.handle.net/11104/0353303File Download Size Commentary Version Access 2024_Smolko_INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES_447.pdf 1 6.9 MB Other open-access - 3.0585354 - FGÚ 2025 RIV NL eng J - Journal Article
Hojná, Silvie - Malínská, H. - Hüttl, M. - Vaňourková, Z. - Marková, I. - Miklánková, D. - Hrdlička, Jaroslav - Papoušek, František - Neckář, Jan - Kujal, P. - Behuliak, Michal - Rauchová, Hana - Kadlecová, Michaela - Sedmera, D. - Neffeová, Kristýna - Zábrodská, E. - Olejníčková, V. - Zicha, Josef - Vaněčková, Ivana
Hepatoprotective and cardioprotective effects of empagliflozin in spontaneously hypertensive rats fed a high-fat diet.
Biomedicine & Pharmacotherapy. Roč. 174, May (2024), č. článku 116520. ISSN 0753-3322. E-ISSN 1950-6007
R&D Projects: GA MŠMT(CZ) LX22NPO5104; GA MZd(CZ) NU21J-02-00039
Institutional support: RVO:67985823
Keywords : cardiac function * kidney function * liver steatosis * metabolic parameters * SGLT-2 inhibition
OECD category: Cardiac and Cardiovascular systems
Impact factor: 7.5, year: 2022
Method of publishing: Open access
https://doi.org/10.1016/j.biopha.2024.116520
Permanent Link: https://hdl.handle.net/11104/0353075File Download Size Commentary Version Access 24_0042_0585354.pdf 0 6.8 MB Publisher’s postprint open-access - 4.0585051 - FZÚ 2025 RIV CH eng J - Journal Article
Neshat, A. - Mahdavi, A. - Yousefshahi, M.R. - Cheraghi, M. - Mohammadi, S. - Eigner, Václav - Kučeráková, Monika - Dušek, Michal - Kaboudin, B. - Halvagar, M.R.
Heterobimetallic Fe(II)-Cu(I) complexes supported with 1,1′-Bis (diphenylphosphino)ferrocene and chelating sulfur donor ligands: biological studies.
Journal of Organometallic Chemistry. Roč. 1005, Feb (2024), č. článku 122972. ISSN 0022-328X. E-ISSN 1872-8561
R&D Projects: GA MŠMT(CZ) EF16_019/0000760
Grant - others:OP VVV - SOLID21(XE) CZ.02.1.01/0.0/0.0/16_019/0000760
Institutional support: RVO:68378271
Keywords : heterobimetallic complexes * dialkyldithiophosphates * single crystal X Ray diffraction * cytotoxic * tyrosinase inhibition * density functional theory
OECD category: Condensed matter physics (including formerly solid state physics, supercond.)
Impact factor: 2.3, year: 2022
Permanent Link: https://hdl.handle.net/11104/0352827 - 5.0583653 - BC 2024 RIV US eng J - Journal Article
Schwark, M. - Yerena, Jose Alberto Martinez - Roehrborn, K. - Hrouzek, P. - Divoká, P. - Štenclová, Lenka - Delawská, K. - Enke, H. - Vorreiter, C. - Wiley, F. - Sippl, W. - Sobotka, R. - Saha, S. - Wilde, S. B. - Mareš, Jan - Niedermeyer, T. H. J.
More than just an eagle killer: The freshwater cyanobacterium iAetokthonos hydrillicola/i produces highly toxic dolastatin derivatives.
Proceedings of the National Academy of Sciences of the United States of America. Roč. 120, č. 40 (2023), č. článku e2219230120. ISSN 0027-8424. E-ISSN 1091-6490
R&D Projects: GA ČR(CZ) GC19-21649J
Institutional support: RVO:60077344
Keywords : antineoplastic agents * anticancer * inhibition * tubulin * cyanotoxin * cytotoxicity * aetokthonostatin * dolastatin
OECD category: Marine biology, freshwater biology, limnology
Impact factor: 11.1, year: 2022
Method of publishing: Open access
https://doi.org/10.1073/pnas.2219230120
Permanent Link: https://hdl.handle.net/11104/0351681 - 6.0582787 - ÚMG 2025 RIV GB eng J - Journal Article
Tykvartova, T. - Miklovic, M. - Kotrc, M. - Škaroupková, P. - Kazdová, L. - Trnovská, J. - Skop, V. - Kolář, Michal - Novotný, Jiří - Melenovský, V.
The impact of phosphodiesterase-5 inhibition or angiotensin-converting enzyme inhibition on right and left ventricular remodeling in heart failure due to chronic volume overload.
PHARMACOL RES PERSPE. Roč. 12, č. 1 (2024), č. článku e1172. ISSN 2052-1707. E-ISSN 2052-1707
Institutional support: RVO:68378050
Keywords : transgenic hypertensive-rats * soluble epoxide hydrolase * natriuretic-peptide * myocardial-infarction * renal dysfunction * sildenafil * expression * pressure * type-5 * model * heart failure * phosphodiesterase-5 inhibition * rats * right ventricle * volume overload
OECD category: Biochemistry and molecular biology
Impact factor: 2.6, year: 2022
Method of publishing: Open access
https://bpspubs.onlinelibrary.wiley.com/doi/10.1002/prp2.1172
Permanent Link: https://hdl.handle.net/11104/0352873 - 7.0582359 - MBÚ 2024 RIV US eng J - Journal Article
Schwark, M. - Martinez Yerena, Jose A. - Roehrborn, K. - Hrouzek, Pavel - Divoká, Petra - Štenclová, L. - Delawská, Kateřina - Enke, H. - Vorreiter, C. - Wiley, F. - Sippl, W. - Sobotka, Roman - Saha, Subhasish - Wilde, Susan B. - Mareš, Jan - Niedermeyer, T. H. J.
More than just an eagle killer: The freshwater cyanobacterium Aetokthonos hydrillicola produces highly toxic dolastatin derivatives.
Proceedings of the National Academy of Sciences of the United States of America. Roč. 120, č. 40 (2023), č. článku e2219230120. ISSN 0027-8424. E-ISSN 1091-6490
R&D Projects: GA ČR(CZ) GC19-21649J
Institutional support: RVO:61388971
Keywords : antineoplastic agents * marine * anticancer * analog * inhibition * tubulin * biosynthesis * efficacy * targets * binding * cyanotoxin * cytotoxicity * aetokthonostatin * dolastatin * biosynthesis
OECD category: Microbiology
Impact factor: 11.1, year: 2022
Method of publishing: Open access
https://www.pnas.org/doi/10.1073/pnas.2219230120
Permanent Link: https://hdl.handle.net/11104/0350572 - 8.0581691 - ÚOCHB 2025 RIV NL eng J - Journal Article
Chrudinová, M. - Kirk, N. S. - Chuard, A. - Venugopal, H. - Zhang, F. - Lubos, Marta - Gelfanov, V. - Páníková, Terezie - Žáková, Lenka - Cutone, J. - Mojares, M. - DiMarchi, R. - Jiráček, Jiří - Altindis, E.
A viral insulin-like peptide inhibits IGF-1 receptor phosphorylation and regulates IGF1R gene expression.
Molecular Metabolism. Roč. 80, February (2024), s. 101863. ISSN 2212-8778. E-ISSN 2212-8778
R&D Projects: GA MŠMT(CZ) LX22NPO5104
Institutional support: RVO:61388963
Keywords : viral insulin/IGF-1 like peptides (VILPs) * IGF-1 * insulin * IGF1 receptor * IGF1 receptor inhibition * biased signaling * iridoviridae
Impact factor: 8.1, year: 2022
Method of publishing: Open access
https://doi.org/10.1016/j.molmet.2023.101863
Permanent Link: https://hdl.handle.net/11104/0349880File Download Size Commentary Version Access 10.1016j.molmet.2023.101863.pdf 0 4 MB Publisher’s postprint open-access - 9.0581090 - ÚOCHB 2024 RIV heb P - Patent Document
Šimková, Adéla - Šácha, Pavel - Sidej, Natan - Ormsby, Tereza - Konvalinka, Jan
תרכובות לעיכוב חלבון הפעלת פיברובלסט.
[Compounds for inhibition of fibroblast activation protein.]
2023. Owner: Ústav organické chemie a biochemie AV ČR, v. v. i. Date of the patent acceptance: 03.04.2023. Patent Number: IL295197. Territorial Protection: národní patent v zemi mimo EU ,mezinárodní patentová ochrana dle Smlouvy o patentové spolupráci.
R&D Projects: GA ČR(CZ) GA19-10280S; GA MZd(CZ) NV15-31379A; GA MŠMT(CZ) EF16_019/0000729; GA MŠMT(CZ) LM2015064; GA MZd(CZ) NU22-03-00318; GA MŠMT LX22NPO5102
Institutional support: RVO:61388963
Keywords : FAP * protease * inhibition
OECD category: Medicinal chemistry
https://israelpatents.justice.gov.il/search/en/patent-extract/295197
Permanent Link: https://hdl.handle.net/11104/0349646File Download Size Commentary Version Access IL295197.pdf 1 202.4 KB Publisher’s postprint open-access - 10.0581089 - ÚOCHB 2024 RIV eng P - Patent Document
Šimková, Adéla - Šácha, Pavel - Sidej, Natan - Ormsby, Tereza - Konvalinka, Jan
Compounds for inhibition of fibroblast activation protein.
2023. Owner: Ústav organické chemie a biochemie AV ČR, v. v. i. Date of the patent acceptance: 06.04.2023. Patent Number: AU2021248368. Territorial Protection: národní patent v zemi mimo EU ,mezinárodní patentová ochrana dle Smlouvy o patentové spolupráci.
R&D Projects: GA ČR(CZ) GA19-10280S; GA MZd(CZ) NV15-31379A; GA MŠMT(CZ) EF16_019/0000729; GA MŠMT(CZ) LM2015064; GA MZd(CZ) NU22-03-00318; GA MŠMT LX22NPO5102
Institutional support: RVO:61388963
Keywords : FAP * protease * inhibition
OECD category: Medicinal chemistry
https://worldwide.espacenet.com/patent/search/family/075953813/publication/AU2021248368B2?q=AU2021248368B2
Permanent Link: https://hdl.handle.net/11104/0349645File Download Size Commentary Version Access AU2021248368B2.pdf 2 5.9 MB Publisher’s postprint open-access