Search results
- 1.0556112 - BFÚ 2023 RIV NL eng J - Journal Article
Šimečková, P. - Pěnčíková, K. - Kováč, O. - Slavík, J. - Parenicova, M. - Vondráček, Jan - Machala, M.
In vitro profiling of toxic effects of environmental polycyclic aromatic hydrocarbons on nuclear receptor signaling, disruption of endogenous metabolism and induction of cellular stress.
Science of the Total Environment. Roč. 815, APR 1 2022 (2022), č. článku 151967. ISSN 0048-9697. E-ISSN 1879-1026
R&D Projects: GA ČR(CZ) GA21-00533S
Institutional support: RVO:68081707
Keywords : pregnane-x-receptor * primary human hepatocytes * aryl-hydrocarbon * estrogen-receptor * mediated activity * hepg2 cells * cross-talk * activation
OECD category: Ecology
Impact factor: 9.8, year: 2022
Method of publishing: Limited access
https://www.sciencedirect.com/science/article/pii/S0048969721070431?via%3Dihub
Permanent Link: https://hdl.handle.net/11104/0339759 - 2.0500086 - ÚEM 2019 RIV CZ eng M - Monography Chapter
Mareková, Dana - Jendelová, Pavla
Hepatocyte Growth on Smooth and Nanoporous Polymer Nanofiber Sheets.
Nanostructures in Biomedicine: Their Regenerative and toxic properties. Praha 3: Proxima Tisk, s.r.o., 2018 - (Pamula, E.), s. 129-136. ISBN 978-80-906655-7-6
R&D Projects: GA MŠMT(CZ) LO1309
Institutional support: RVO:68378041
Keywords : nanofibers * masenchymal stem cells * hepatocytes
OECD category: Biophysics
Permanent Link: http://hdl.handle.net/11104/0293712 - 3.0482673 - FGÚ 2018 RIV CZ eng J - Journal Article
Svoboda, Petr - Křížová, E. - Čeňková, K. - Vápenková, K. - Zídková, J. - Zídek, Václav - Škop, V.
Visfatin Is Actively Secreted In Vitro From U-937 Macrophages, but Only Passively Released From 3T3-L1 Adipocytes and HepG2 Hepatocytes.
Physiological Research. Roč. 66, č. 4 (2017), s. 709-714. ISSN 0862-8408. E-ISSN 1802-9973
R&D Projects: GA ČR(CZ) GA16-04859S; GA ČR(CZ) GA13-04580S
Institutional support: RVO:67985823
Keywords : Nampt * Visfatin * active secretion * adipocytes * hepatocytes * macrophages
OECD category: Endocrinology and metabolism (including diabetes, hormones)
Impact factor: 1.324, year: 2017
Permanent Link: http://hdl.handle.net/11104/0278203 - 4.0477884 - ÚI 2018 CZ eng J - Journal Article
Smutný, T. - Duintjer Tebbens, Jurjen - Pávek, P.
Bioinformatic analysis of miRNAs targeting the key nuclear receptors regulating CYP3A4 gene expression: The challenge of the CYP3A4 "missing heritability'' enigma.
Journal of Applied Biomedicine. Roč. 13, č. 3 (2015), s. 181-188. ISSN 1214-021X. E-ISSN 1214-0287
Keywords : pregnane x receptor * microrna binding-sites * vitamin-d-receptor * transcriptional regulation * human liver * cytochrome-p450 3a4 * human hepatocytes * factor 4-alpha * in-silico * identification * miRNA * Gene regulation * cyp3a4 * Cytochrome P450 * Metabolism
Subject RIV: FR - Pharmacology ; Medidal Chemistry
Impact factor: 1.509, year: 2015
Permanent Link: http://hdl.handle.net/11104/0274103 - 5.0471935 - BFÚ 2017 RIV GB eng J - Journal Article
Vondráček, Jan - Pěnčíková, K. - Neca, J. - Ciganek, M. - Grycová, A. - Dvořák, Z. - Machala, M.
Assessment of the aryl hydrocarbon receptor-mediated activities of polycyclic aromatic hydrocarbons in a human cell-based reporter gene assay.
Environmental Pollution. Roč. 220, JAN2017 (2017), s. 307-316. ISSN 0269-7491. E-ISSN 1873-6424
R&D Projects: GA ČR GA13-07711S
Institutional support: RVO:68081707
Keywords : rat primary hepatocytes * liver epithelial-cells * cancer-risk assessment
Subject RIV: BO - Biophysics
Impact factor: 4.358, year: 2017
Permanent Link: http://hdl.handle.net/11104/0269297 - 6.0457718 - FGÚ 2016 RIV CZ eng J - Journal Article
Sobotka, O. - Drahota, Zdeněk - Kučera, O. - Endlicher, R. - Rauchová, Hana - Červinková, Z.
The effect of alpha-tocopheryl succinate on succinate respiration in rat liver mitochondria.
Physiological Research. Roč. 64, Suppl.5 (2015), S609-S615. ISSN 0862-8408. E-ISSN 1802-9973
Institutional support: RVO:67985823
Keywords : tocopheryl succinate * Complex II * liver * mitochondria * homogenate * hepatocytes
Subject RIV: ED - Physiology
Impact factor: 1.643, year: 2015
Permanent Link: http://hdl.handle.net/11104/0258085 - 7.0428971 - FGÚ 2015 RIV CZ eng J - Journal Article
Garnol, T. - Endlicher, R. - Kučera, O. - Drahota, Zdeněk - Červinková, Z.
Impairment of mitochondrial function of rat hepatocytes by high fat diet and oxidative stress.
Physiological Research. Roč. 63, č. 2 (2014), s. 271-274. ISSN 0862-8408. E-ISSN 1802-9973
R&D Projects: GA MŠMT(CZ) LL1204
Grant - others:Univerzita Karlova(CZ) PRVOUK P37/02
Institutional support: RVO:67985823
Keywords : hepatocytes * high fat diet * mitochondrial activities * ROS
Subject RIV: ED - Physiology
Impact factor: 1.293, year: 2014
Permanent Link: http://hdl.handle.net/11104/0234191 - 8.0421049 - ÚEB 2014 RIV US eng J - Journal Article
Haider, C. - Grubinger, M. - Řezníčková, Eva - Weiss, T.S. - Rotheneder, H. - Miklos, W. - Berger, W. - Jorda, Radek - Zatloukal, M. - Gucký, T. - Strnad, Miroslav - Kryštof, Vladimír - Mikulits, W.
Novel Inhibitors of Cyclin-Dependent Kinases Combat Hepatocellular Carcinoma without Inducing Chemoresistance.
Molecular Cancer Therapeutics. Roč. 12, č. 10 (2013), s. 1947-1957. ISSN 1535-7163. E-ISSN 1538-8514
R&D Projects: GA ČR GAP305/12/0783; GA ČR GA301/08/1649
Institutional research plan: CEZ:AV0Z50380511
Keywords : PRIMARY HUMAN HEPATOCYTES * SELICICLIB R-ROSCOVITINE * CELL-CYCLE
Subject RIV: CE - Biochemistry
Impact factor: 6.107, year: 2013
Permanent Link: http://hdl.handle.net/11104/0227508File Download Size Commentary Version Access 2013_Haider_MOLECULAR CANCER THERAPEUTICS_1947-1957.pdf 11 1.6 MB Other open-access - 9.0420631 - ÚEM 2014 RIV GR eng J - Journal Article
Mareková, Dana - Lesný, Petr - Jendelová, Pavla - Michálek, Jiří - Kostecká, Petra - Přádný, Martin - Martinová, L. - Pantoflíček, T. - Ryska, M. - Syková, Eva
Hepatocyte growth on polycapronolactone and 2-hydroxyethylmethacrylate nanofiber sheets enhanced by bone marrow-derived mesenchymal stromal cells.
Hepato-Gastroenterology. Roč. 60, č. 125 (2013), s. 1156-1163. ISSN 0172-6390
R&D Projects: GA ČR GA304/07/1129; GA AV ČR KAN200520804; GA MŠMT 1M0538
Institutional research plan: CEZ:AV0Z50390703
Institutional support: RVO:61389013 ; RVO:68378041
Keywords : nanofibers * hepatocytes * Bioartificial Liver Assist Device
Subject RIV: FH - Neurology
Impact factor: 0.907, year: 2013
Permanent Link: http://hdl.handle.net/11104/0227160 - 10.0395422 - MBÚ 2014 RIV US eng J - Journal Article
Vrba, J. - Gažák, Radek - Kuzma, Marek - Papoušková, B. - Vacek, J. - Weiszenstein, M. - Křen, Vladimír - Ulrichová, J.
A Novel Semisynthetic Flavonoid 7-O-Galloyltaxifolin Upregulates Heme Oxygenase-1 in RAW264.7 Cells via MAPK/Nrf2 Pathway.
Journal of Medicinal Chemistry. Roč. 56, č. 3 (2013), s. 856-866. ISSN 0022-2623. E-ISSN 1520-4804
R&D Projects: GA ČR(CZ) GAP301/11/0767
Institutional support: RVO:61388971
Keywords : OXIDATIVE STRESS * HUMAN HEPATOCYTES * RESPONSE ELEMENT
Subject RIV: CE - Biochemistry
Impact factor: 5.480, year: 2013
Permanent Link: http://hdl.handle.net/11104/0223445