Search results

  1. 1.
    0556112 - BFÚ 2023 RIV NL eng J - Journal Article
    Šimečková, P. - Pěnčíková, K. - Kováč, O. - Slavík, J. - Parenicova, M. - Vondráček, Jan - Machala, M.
    In vitro profiling of toxic effects of environmental polycyclic aromatic hydrocarbons on nuclear receptor signaling, disruption of endogenous metabolism and induction of cellular stress.
    Science of the Total Environment. Roč. 815, APR 1 2022 (2022), č. článku 151967. ISSN 0048-9697. E-ISSN 1879-1026
    R&D Projects: GA ČR(CZ) GA21-00533S
    Institutional support: RVO:68081707
    Keywords : pregnane-x-receptor * primary human hepatocytes * aryl-hydrocarbon * estrogen-receptor * mediated activity * hepg2 cells * cross-talk * activation
    OECD category: Ecology
    Impact factor: 9.8, year: 2022
    Method of publishing: Limited access
    https://www.sciencedirect.com/science/article/pii/S0048969721070431?via%3Dihub
    Permanent Link: https://hdl.handle.net/11104/0339759
     
     
  2. 2.
    0500086 - ÚEM 2019 RIV CZ eng M - Monography Chapter
    Mareková, Dana - Jendelová, Pavla
    Hepatocyte Growth on Smooth and Nanoporous Polymer Nanofiber Sheets.
    Nanostructures in Biomedicine: Their Regenerative and toxic properties. Praha 3: Proxima Tisk, s.r.o., 2018 - (Pamula, E.), s. 129-136. ISBN 978-80-906655-7-6
    R&D Projects: GA MŠMT(CZ) LO1309
    Institutional support: RVO:68378041
    Keywords : nanofibers * masenchymal stem cells * hepatocytes
    OECD category: Biophysics
    Permanent Link: http://hdl.handle.net/11104/0293712
     
     
  3. 3.
    0482673 - FGÚ 2018 RIV CZ eng J - Journal Article
    Svoboda, Petr - Křížová, E. - Čeňková, K. - Vápenková, K. - Zídková, J. - Zídek, Václav - Škop, V.
    Visfatin Is Actively Secreted In Vitro From U-937 Macrophages, but Only Passively Released From 3T3-L1 Adipocytes and HepG2 Hepatocytes.
    Physiological Research. Roč. 66, č. 4 (2017), s. 709-714. ISSN 0862-8408. E-ISSN 1802-9973
    R&D Projects: GA ČR(CZ) GA16-04859S; GA ČR(CZ) GA13-04580S
    Institutional support: RVO:67985823
    Keywords : Nampt * Visfatin * active secretion * adipocytes * hepatocytes * macrophages
    OECD category: Endocrinology and metabolism (including diabetes, hormones)
    Impact factor: 1.324, year: 2017
    Permanent Link: http://hdl.handle.net/11104/0278203
     
     
  4. 4.
    0477884 - ÚI 2018 CZ eng J - Journal Article
    Smutný, T. - Duintjer Tebbens, Jurjen - Pávek, P.
    Bioinformatic analysis of miRNAs targeting the key nuclear receptors regulating CYP3A4 gene expression: The challenge of the CYP3A4 "missing heritability'' enigma.
    Journal of Applied Biomedicine. Roč. 13, č. 3 (2015), s. 181-188. ISSN 1214-021X. E-ISSN 1214-0287
    Keywords : pregnane x receptor * microrna binding-sites * vitamin-d-receptor * transcriptional regulation * human liver * cytochrome-p450 3a4 * human hepatocytes * factor 4-alpha * in-silico * identification * miRNA * Gene regulation * cyp3a4 * Cytochrome P450 * Metabolism
    Subject RIV: FR - Pharmacology ; Medidal Chemistry
    Impact factor: 1.509, year: 2015
    Permanent Link: http://hdl.handle.net/11104/0274103
     
     
  5. 5.
    0471935 - BFÚ 2017 RIV GB eng J - Journal Article
    Vondráček, Jan - Pěnčíková, K. - Neca, J. - Ciganek, M. - Grycová, A. - Dvořák, Z. - Machala, M.
    Assessment of the aryl hydrocarbon receptor-mediated activities of polycyclic aromatic hydrocarbons in a human cell-based reporter gene assay.
    Environmental Pollution. Roč. 220, JAN2017 (2017), s. 307-316. ISSN 0269-7491. E-ISSN 1873-6424
    R&D Projects: GA ČR GA13-07711S
    Institutional support: RVO:68081707
    Keywords : rat primary hepatocytes * liver epithelial-cells * cancer-risk assessment
    Subject RIV: BO - Biophysics
    Impact factor: 4.358, year: 2017
    Permanent Link: http://hdl.handle.net/11104/0269297
     
     
  6. 6.
    0457718 - FGÚ 2016 RIV CZ eng J - Journal Article
    Sobotka, O. - Drahota, Zdeněk - Kučera, O. - Endlicher, R. - Rauchová, Hana - Červinková, Z.
    The effect of alpha-tocopheryl succinate on succinate respiration in rat liver mitochondria.
    Physiological Research. Roč. 64, Suppl.5 (2015), S609-S615. ISSN 0862-8408. E-ISSN 1802-9973
    Institutional support: RVO:67985823
    Keywords : tocopheryl succinate * Complex II * liver * mitochondria * homogenate * hepatocytes
    Subject RIV: ED - Physiology
    Impact factor: 1.643, year: 2015
    Permanent Link: http://hdl.handle.net/11104/0258085
     
     
  7. 7.
    0428971 - FGÚ 2015 RIV CZ eng J - Journal Article
    Garnol, T. - Endlicher, R. - Kučera, O. - Drahota, Zdeněk - Červinková, Z.
    Impairment of mitochondrial function of rat hepatocytes by high fat diet and oxidative stress.
    Physiological Research. Roč. 63, č. 2 (2014), s. 271-274. ISSN 0862-8408. E-ISSN 1802-9973
    R&D Projects: GA MŠMT(CZ) LL1204
    Grant - others:Univerzita Karlova(CZ) PRVOUK P37/02
    Institutional support: RVO:67985823
    Keywords : hepatocytes * high fat diet * mitochondrial activities * ROS
    Subject RIV: ED - Physiology
    Impact factor: 1.293, year: 2014
    Permanent Link: http://hdl.handle.net/11104/0234191
     
     
  8. 8.
    0421049 - ÚEB 2014 RIV US eng J - Journal Article
    Haider, C. - Grubinger, M. - Řezníčková, Eva - Weiss, T.S. - Rotheneder, H. - Miklos, W. - Berger, W. - Jorda, Radek - Zatloukal, M. - Gucký, T. - Strnad, Miroslav - Kryštof, Vladimír - Mikulits, W.
    Novel Inhibitors of Cyclin-Dependent Kinases Combat Hepatocellular Carcinoma without Inducing Chemoresistance.
    Molecular Cancer Therapeutics. Roč. 12, č. 10 (2013), s. 1947-1957. ISSN 1535-7163. E-ISSN 1538-8514
    R&D Projects: GA ČR GAP305/12/0783; GA ČR GA301/08/1649
    Institutional research plan: CEZ:AV0Z50380511
    Keywords : PRIMARY HUMAN HEPATOCYTES * SELICICLIB R-ROSCOVITINE * CELL-CYCLE
    Subject RIV: CE - Biochemistry
    Impact factor: 6.107, year: 2013
    Permanent Link: http://hdl.handle.net/11104/0227508
    FileDownloadSizeCommentaryVersionAccess
    2013_Haider_MOLECULAR CANCER THERAPEUTICS_1947-1957.pdf111.6 MBOtheropen-access
     
     
  9. 9.
    0420631 - ÚEM 2014 RIV GR eng J - Journal Article
    Mareková, Dana - Lesný, Petr - Jendelová, Pavla - Michálek, Jiří - Kostecká, Petra - Přádný, Martin - Martinová, L. - Pantoflíček, T. - Ryska, M. - Syková, Eva
    Hepatocyte growth on polycapronolactone and 2-hydroxyethylmethacrylate nanofiber sheets enhanced by bone marrow-derived mesenchymal stromal cells.
    Hepato-Gastroenterology. Roč. 60, č. 125 (2013), s. 1156-1163. ISSN 0172-6390
    R&D Projects: GA ČR GA304/07/1129; GA AV ČR KAN200520804; GA MŠMT 1M0538
    Institutional research plan: CEZ:AV0Z50390703
    Institutional support: RVO:61389013 ; RVO:68378041
    Keywords : nanofibers * hepatocytes * Bioartificial Liver Assist Device
    Subject RIV: FH - Neurology
    Impact factor: 0.907, year: 2013
    Permanent Link: http://hdl.handle.net/11104/0227160
     
     
  10. 10.
    0395422 - MBÚ 2014 RIV US eng J - Journal Article
    Vrba, J. - Gažák, Radek - Kuzma, Marek - Papoušková, B. - Vacek, J. - Weiszenstein, M. - Křen, Vladimír - Ulrichová, J.
    A Novel Semisynthetic Flavonoid 7-O-Galloyltaxifolin Upregulates Heme Oxygenase-1 in RAW264.7 Cells via MAPK/Nrf2 Pathway.
    Journal of Medicinal Chemistry. Roč. 56, č. 3 (2013), s. 856-866. ISSN 0022-2623. E-ISSN 1520-4804
    R&D Projects: GA ČR(CZ) GAP301/11/0767
    Institutional support: RVO:61388971
    Keywords : OXIDATIVE STRESS * HUMAN HEPATOCYTES * RESPONSE ELEMENT
    Subject RIV: CE - Biochemistry
    Impact factor: 5.480, year: 2013
    Permanent Link: http://hdl.handle.net/11104/0223445
     
     

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